Abstract：
:The distribution of neurocalcin-immunoreactive (NC-ir) primary sensory neurons was examined in the trigeminal ganglion (TG), mesencephalic trigeminal tract nucleus (Mes5) and intraoral structures. NC-ir primary sensory neurons were located in the TG but not the Mes5. The coexpression study demonstrated that virtually all NC-ir TG neurons exhibited S100-immunoreactivity (-ir). In the tooth pulp, NC-ir nerve fibers were observed in the subodontoblastic and odontoblastic layers. Immunoelectron microscopic and retrograde tracing methods revealed that myelinated pulpal axons derived from the TG mostly exhibited the ir. In the periodontal ligament, bush-like endings showed NC-ir. These endings were morphologically identical to Ruffini-like endings. The present study suggests that NC-ir trigeminal primary sensory neurons have their cell bodies in the TG. Their peripheral axons are probably myelinated. Such neurons include pulpal nociceptors and low-threshold mechanoreceptors.
journal_name
Brain Resjournal_title
Brain researchauthors
Ichikawa H,Hidaka H,Sugimoto Tdoi
10.1016/s0006-8993(00)02175-2subject
Has Abstractpub_date
2000-05-02 00:00:00pages
152-6issue
1eissn
0006-8993issn
1872-6240pii
S0006-8993(00)02175-2journal_volume
864pub_type
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