Glycine response in isolated dorsal cochlear nucleus of C57BL/6J mouse.

abstract：:A new compound, 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), has been evaluated as an excitatory amino acid receptor antagonist using electrophysiological assays and radioligand binding. In autoradiographic preparations, CPP reduces L-[3H]glutamate binding in regions of the hippocampus rich in N-m...

journal_title：Brain research

authors： Harris EW,Ganong AH,Monaghan DT,Watkins JC,Cotman CW

更新日期：1986-09-10 00:00:00

abstract：:We examined the effect of gangliosides on Schwann cell cultures isolated from neonatal rat sciatic nerves. Addition of gangliosides (GM1, GM3, and ganglioside mixture) at concentrations between 0.25 and 2 mg/ml significantly diminished both the baseline rate of proliferation of the Schwann cells and their response to ...

journal_title：Brain research

authors： Sobue G,Taki T,Yasuda T,Mitsuma T

更新日期：1988-12-06 00:00:00

abstract：:This study deals with the synaptology, morphologically identified postsynaptic targets, and origin of somatostatin (SOM) fibers in the rat lateral septal area (LSA) with special reference to those forming pericellular baskets. Septal vibratome sections were immunostained for SOM-14 in 3 experimental groups: control an...

journal_title：Brain research

authors： Jakab RL,Leranth C

更新日期：1991-11-22 00:00:00

abstract：:The influence of emotion on cognition plays an important role in people's everyday life as well as in psychiatric and neurological disorders. The present study used fMRI to examine the neural correlates of cognitive-emotional interactions and its inter-individual differences. Twenty-one healthy males performed a 0-bac...

journal_title：Brain research

authors： Habel U,Koch K,Pauly K,Kellermann T,Reske M,Backes V,Seiferth NY,Stöcker T,Kircher T,Amunts K,Jon Shah N,Schneider F

更新日期：2007-06-04 00:00:00

abstract：:The localization of the receptor for apamin, a specific toxin for one class of sensitive Ca2+-dependent K+ channel, was studied in rat brain using an in vitro autoradiographic technique. Radiolabeled monoiodoapamin binds specifically to rat brain sections with a high affinity (Kd = 25 pM) to a single class of sites. A...

journal_title：Brain research

authors： Mourre C,Hugues M,Lazdunski M

更新日期：1986-09-24 00:00:00

abstract：:The distribution of carbonic anhydrase (CA) activity was determined histochemically using Hansson's cobalt phosphate method in cross-sections of peripheral nerves from rats. As the studied nerves contain either efferent, proprioceptive or exteroceptive myelinated fibres, our survey particularly focused on the question...

journal_title：Brain research

authors： Szabolcs MJ,Kopp M,Schaden GE

更新日期：1989-07-17 00:00:00

abstract：:The olfactory sensory neurons are unique in the vertebrate nervous system in that they are replaced following experimentally induced degeneration. Unilateral removal of the olfactory bulb in hamster results in degeneration of all mature receptor neurons followed by a neurogenesis and partial replacement of the recepto...

journal_title：Brain research

authors： Costanzo RM

更新日期：1984-07-30 00:00:00

abstract：:We investigated the brain-stem pathway(s) by which electrical stimulation of the central cut end of the lingual nerve (LN) evokes parasympathetic reflex vasodilatation in the palate contralateral to the stimulated side. This occurs in artificially ventilated, cervically vagosympathectomized cats deeply anesthetized wi...

journal_title：Brain research

authors： Mizuta K,Izumi H

更新日期：2004-09-10 00:00:00

abstract：:Application of 4-aminopyridine (4-AP) has previously been reported to produce different patterns of epileptiform discharges in entorhinal cortex (EC)-hippocampal slices: recurrent short discharges (RSDs) in hippocampal area CA1, seizure-like events (SLEs) and negative-going potentials (NGPs) in the medial entorhinal c...

journal_title：Brain research

authors： Brückner C,Heinemann U

更新日期：2000-03-17 00:00:00

abstract：:This study was done in urethane anesthetized, ovariectomized (OVX) female rats that were either implanted or not implanted with silastic capsules containing17β-estradiol (E2) to investigate the effect of systemic changes in E2 on the discharge rate of subfornical organ (SFO) neurons that projected to supraoptic nucleu...

journal_title：Brain research

authors： Ciriello J,Roder S

更新日期：2013-08-14 00:00:00

abstract：:L-[35S]Methionine was injected into the dorsal root ganglion (L5) of the adult rat, and migration of the neurofilament polypeptides (the triplet with molecular weights of 200,000, 160,000 and 68,000 daltons), alpha- and beta-tubulins and actin in the sciatic nerve and the dorsal root was quantitatively determined and ...

journal_title：Brain research

authors： Komiya Y,Kurokawa M

更新日期：1980-05-26 00:00:00

abstract：:Proliferative response of astrocytes to unilateral injury of the cerebral hemisphere was investigated in 30-day-old rats using a combination of [3H]thymidine autoradiography and immunocytochemical staining for glial fibrillary acidic protein. At different intervals following injury the animals were injected with [3H]t...

journal_title：Brain research

authors： Janeczko K

更新日期：1989-04-24 00:00:00

abstract：:Unilateral visual cortex ablations in neonatal rabbits produced no detectable loss of ganglion cells in the contralateral retina following a survival period of 3, 4 or 8 months. Analysis of neuron size distributions and neuron densities from whole-mounted retinas indicate that transneuronal retrograde degeneration doe...

journal_title：Brain research

authors： Wilkes M,Zingaro G,Murphy EH

更新日期：1985-08-01 00:00:00

abstract：:We have found that daily subcutaneous injection with a maximum tolerated dose (MTD) of the mGluR2/3 agonist LY379268 (20mg/kg) beginning at 4 weeks dramatically improves the phenotype in R6/2 mice. For example, we observed normalization of motor function in distance traveled, speed, the infrequency of pauses, and the ...

journal_title：Brain research

authors： Reiner A,Wang HB,Del Mar N,Sakata K,Yoo W,Deng YP

更新日期：2012-09-14 00:00:00

abstract：:Degeneration of noradrenergic neurons in the locus coeruleus (LC) and dysfunction of the prefrontal cortex were regarded as playing a specific role in the occurrence of non-motor symptoms in Parkinson's disease. The present study examined the spontaneous firing rate and firing pattern of medial prefrontal cortex (mPFC...

journal_title：Brain research

authors： Wang Y,Zhang QJ,Liu J,Ali U,Gui ZH,Hui YP,Wang T,Chen L,Li Q

更新日期：2010-04-09 00:00:00

abstract：:The effect of five daily intraperitoneal (i.p.) injections of NT69L on in vitro dopamine release, uptake, and [(3)H]NT binding in rat striatal tissue was investigated. NT69L perfusion increased K(+)-evoked and electrically evoked [(3)H]DA release. NT receptor-1 antagonist SR48692 inhibited the stimulatory effect of NT...

journal_title：Brain research

authors： Wang R,Boules M,Tiner W,Richelson E

更新日期：2004-10-29 00:00:00

abstract：:We investigated the bilateral organization of the descending spinal sympathetic projections that subserve adrenomedullary stimulation caused by insulin hypoglycemia or 2-deoxyglucose (2DG) cellular glucopenia in adult rats with right-sided hemisection of the cord at C6-C7 (i.e. above the site of origin of the adrenal ...

journal_title：Brain research

authors： Gagner JP,Gauthier S,Sourkes TL

更新日期：1985-01-28 00:00:00

abstract：:Mice of the BALB/c strain were bilaterally implanted with electrodes in the lateral entorhinal cortex (EC) in order to study the influence of post-trial EC stimulation on memory. The learning task was a food reinforced operant conditioning. At one of several time intervals after a first learning session, the experimen...

journal_title：Brain research

authors： Gauthier M,Destrade C,Soumireu-Mourat B

更新日期：1982-02-11 00:00:00

abstract：:The levels of PLCgamma, a phospholipase C (PLC) isozyme, were higher in the cytosol fraction than in the membrane fraction in several control brain regions. The levels of PLCgamma were significantly elevated in the membrane, but not in the cytosolic fraction of the hippocampus of AD subjects. In the superior and middl...

journal_title：Brain research

authors： Zhang D,Dhillon H,Prasad MR,Markesbery WR

更新日期：1998-11-16 00:00:00

abstract：:In order to obtain further insight into the interactions between the purinergic and dopaminergic pathways in the striatum, we studied both metabolisms simultaneously, using a microdialysis technique in 1-methyl-1,4-phenylpyridinium ion (MPP+) unilaterally-denervated conscious rats. In these rats the contralateral side...

journal_title：Brain research

authors： Ballarin M,Reiriz J,Ambrosio S,Camps M,Blesa R,Mahy N

更新日期：1989-03-27 00:00:00

abstract：:When female golden hamsters are maintained on a photoperiod of less than 12.5 h of light per day, they go into a pineal gland-induced anestrus in 6-10 weeks. This acyclicity is similar in certain respects to the testicular regression which occurs in male golden hamsters maintained on a short photoperiod. A recent stud...

journal_title：Brain research

authors： Pieper DR,Samyn MM,Heverly RN

更新日期：1986-08-13 00:00:00

abstract：:The characteristics of [3H]sulpiride binding to the D2 dopamine receptor in rat striatal membranes were examined under several conditions. In the absence of sodium ions, the specific binding of [3H]sulpiride could not be detected. In the direct binding experiment, at 25 degrees C, the affinity of [3H]sulpiride for D2 ...

journal_title：Brain research

authors： Imafuku J

更新日期：1987-02-03 00:00:00

abstract：:Arginase-1, a marker for M2 phenotype alternatively activated macrophages, inhibits inflammation and is associated with phagocytosis of cell debris and apoptotic cells. We analyzed the expression of arginase-1, a competitive enzyme of inducible nitric oxide synthase (iNOS), in the spinal cords of Lewis rats with exper...

journal_title：Brain research

authors： Ahn M,Yang W,Kim H,Jin JK,Moon C,Shin T

更新日期：2012-05-09 00:00:00

abstract：:Lesions to the ventromedial hypothalamus (VMH) inhibit receptive sexual behavior in the whiptail lizard, Cnemidophorus uniparens, an all-female species. All lesions to the VMH that effectively abolished receptivity specifically damaged the dorsal lateral VMH, an area containing high concentrations of estrogen receptor...

journal_title：Brain research

authors： Kendrick AM,Rand MS,Crews D

更新日期：1995-05-22 00:00:00

abstract：:Hypothalamic stimulation generally inhibits baroreflex-induced bradycardia. However, we have noted discrete areas of the rat hypothalamus which facilitate reflex bradycardia. The effects of hypothalamic stimulation on baroreflex-induced changes in heart rate were investigated in urethane-anesthetized rats (1.2 g/kg, i...

journal_title：Brain research

authors： Pardini BJ,Patel KP,Schmid PG,Lund DD

更新日期：1986-10-08 00:00:00

abstract：:Arg-vasopressin (AVP) containing neurons are one of the output paths from the suprachiasmatic nucleus (SCN), the center of the biological clock. AVP mRNA transcription is controlled by a negative feedback loop of clock genes. Circadian rhythm of melatonin release from the pineal gland is regulated by the SCN via the p...

journal_title：Brain research

authors： Isobe Y,Nishino H

更新日期：2004-07-09 00:00:00

abstract：:A newly discovered cell-to-cell communication system involves small, membrane-enveloped nanovesicles, called exosomes. We describe here how these extracellular nanoparticles were discovered and how it became gradually apparent that they play fundamental roles in regulation of physiological functions and pathological p...

journal_title：Brain research

authors： Kawikova I,Askenase PW

更新日期：2015-08-18 00:00:00

abstract：:In the companion study (Dev. Brain Res., 34 (1987) 223-233), we showed that a monocular injection of antibodies against ox large retinal ganglion cells produces a 53% (low concentration) to 82% (high concentration) loss of Y-cells in lateral geniculate nucleus (LGN) layers A and A1 that receive inputs from the antibod...

journal_title：Brain research

authors： McCall MA,Spear PD,Crabtree JW,Kornguth SE

更新日期：1987-08-01 00:00:00

abstract：:Decision making is commonly conceived to reflect the interplay of mutually antagonistic systems: executive processes must inhibit affective information to make adaptive choices. Consistent with this interpretation, prior studies have shown that the dorsolateral prefrontal cortex (dlPFC) is activated by executive proce...

journal_title：Brain research

authors： Mullette-Gillman OA,Detwiler JM,Winecoff A,Dobbins I,Huettel SA

更新日期：2011-06-13 00:00:00

abstract：:Monkeys were trained to depress a hold key for a period of 2 sec. After this hold period, either a red or a green cue lamp appeared in random sequence. The red lamp required the monkey to move his hand from the hold key to a target button within 1 sec of the cue presentation. The green lamp required continued depressi...

journal_title：Brain research

authors： Otero JB

更新日期：1976-01-09 00:00:00