Abstract:
:A study was made of the release of excitatory, inhibitory and other amino acids from epileptic foci induced in the sensorimotor cortex of rats by cobalt implantation. A new in vivo superfusion method was employed which gives free movement to the animals and allows study over periods of days and weeks. Most amino acids showed maximum release rates during the first 2 or 3 days after surgery. Glutamate showed maximum release rates during days 3-6 when epileptic limb jerks were at a maximum. This pattern was not seen for other physiologically active amino acids.
journal_name
Brain Resjournal_title
Brain researchauthors
Dodd PR,Bradford HFdoi
10.1016/0006-8993(76)90781-2subject
Has Abstractpub_date
1976-07-30 00:00:00pages
377-88issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(76)90781-2journal_volume
111pub_type
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