Abstract：
:In rats under urethane, iontophoretic applications of GABA (30-60 nA) in the str. pyramidale of CA1, showed a rapidly fading inhibitory effect. By contrast, GABA had a well-maintained inhibitory effect in str. radiatum. During iontophoresis of nipecotic acid (30-85 nA) identical applications of GABA in str. pyramidale caused a more prominent depression without fading, which suggests that removal of GABA, by uptake, can at least in part account for 'fading'. Nipecotic acid also prolonged the paired-pulse inhibition, presumably by prolonging the duration of inhibitory postsynaptic potentials.
journal_name
Brain Resjournal_title
Brain researchauthors
Dalkara Tdoi
10.1016/0006-8993(86)91309-0subject
Has Abstractpub_date
1986-02-26 00:00:00pages
314-9issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(86)91309-0journal_volume
366pub_type
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