Acetylcholine release from dissociated striatal cells.

abstract：:Evidence is presented for the occurrence of a unique opiate alkaloid-selective, opioid peptide-insensitive binding site in N18TG2 mouse neuroblastoma cells and in late passage hybrid F-11 cells, derived from N18TG2 neuroblastoma cells and rat dorsal root ganglion cells. Those cells lacked classical opioid peptide-sens...

journal_title：Brain research

authors： Cruciani RA,Dvorkin B,Klinger HP,Makman MH

更新日期：1994-12-26 00:00:00

abstract：:Neuropeptide Y (NPY) has been detected immunocytochemically in cerebral cortex and subcortical white matter of the primate frontal, parietal, temporal, and occipital lobes. Because little is known about NPY in the primate insular lobe and because peptides play an important role in normal neuronal functioning and alter...

journal_title：Brain research

authors： Augustine JR,Mascagni F,McDonald AJ,Blake CA

更新日期：1993-02-19 00:00:00

abstract：:The effects of apamin on rat locus coeruleus (LC) neurons were studied in a brain slice preparation with intracellular recording. Bath application of apamin (2-500 nM) reduced the amplitude of an intermediate component of the afterhyperpolarization (AHP) following single spontaneous action potentials, but did not chan...

journal_title：Brain research

authors： Osmanović SS,Shefner SA,Brodie MS

更新日期：1990-10-22 00:00:00

abstract：:BW 1003C87, 5-(2,3,5-trichlorophenyl)-2,4-diaminopyrimidine ethane sulphonic acid, has been tested for its in vitro and in vivo effects on glutamate release in rat brain tissue, and for its cerebro-protective action in two rodent models of cerebral ischemia. In rat brain slices the release of glutamate evoked by verat...

journal_title：Brain research

authors： Meldrum BS,Swan JH,Leach MJ,Millan MH,Gwinn R,Kadota K,Graham SH,Chen J,Simon RP

更新日期：1992-10-09 00:00:00

abstract：:It has been well established that the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) opener, diazoxide, has protective effects on the heart and brain following ischemia/reperfusion injury. However, the mechanism of the neuroprotective effects of diazoxide remains unclear. This study highlights the anti-apo...

journal_title：Brain research

authors： Zhang H,Wang ZQ,Zhao DY,Zheng DM,Feng J,Song LC,Luo Y

更新日期：2011-01-25 00:00:00

abstract：:The stress-related neurohormone, corticotropin-releasing factor (CRF), also acts as a neurotransmitter to activate the brain noradrenergic nucleus, locus coeruleus (LC). Previous electrophysiological findings demonstrating that tonic CRF secretion in the LC is increased in adrenalectomized rats suggest that activity o...

journal_title：Brain research

authors： Lechner SM,Valentino RJ

更新日期：1999-01-16 00:00:00

abstract：:Experiments were performed to test the hypothesis that subarachnoid hemorrhage (SAH) causes functionally relevant perturbations of cyclooxygenase activity in cerebral arteries. Four groups of rabbits were formed: (I) controls; (II) sham injected animals (2 ml physiological solution in the cisterna magna); (III) SAH gr...

journal_title：Brain research

authors： Tran Dinh YR,Roche S,Debdi M,Seylaz J,Sercombe R

更新日期：1998-04-20 00:00:00

abstract：:These experiments examined the effects of intra-amygdala injections of NMDA receptor antagonists on the acquisition and retention of inhibitory avoidance. In Expt. I, rats received bilateral intra-amygdala injections of the NMDA antagonists D,L-AP5 (1-10 micrograms), D-AP5 (0.03-1 micrograms), CPP (0.125 or 0.375 micr...

journal_title：Brain research

authors： Kim M,McGaugh JL

更新日期：1992-07-10 00:00:00

abstract：:Sequential effects--reduced behavioral interference after incongruent trials-provide a unique opportunity to examine the influence of previous experience on current attentional processing. We conducted a theoretical analysis of performance in the Simon paradigm to distinguish an attention account (conflict adaptation)...

journal_title：Brain research

authors： Chen S,Melara RD

更新日期：2009-11-10 00:00:00

abstract：:Using [3H]para-aminoclonidine, alpha 2 adrenergic binding sites have been mapped in the rat and human CNS using in vitro labeling autoradiographic techniques. In both the rat and human thoracic spinal cord, high densities of alpha 2 binding sites were associated with the substantia gelatinosa and the intermediolateral...

journal_title：Brain research

authors： Unnerstall JR,Kopajtic TA,Kuhar MJ

更新日期：1984-03-01 00:00:00

abstract：:For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...

journal_title：Brain research

authors： Ding R,Asada H,Obata K

更新日期：1998-07-27 00:00:00

abstract：:Twelve weeks after focal ventrolateral cerebrocortical suction lesions (ca. 12 X 4 mm) were made in rats, concentrations of the monoamines norepinephrine (NE), dopamine (DA), and serotonin (5-HT) and their metabolites were measured in several cortical and subcortical brain regions using high performance liquid chromat...

journal_title：Brain research

authors： Finklestein S,Campbell A,Baldessarini RJ,Moya KL,Haber SN

更新日期：1985-10-07 00:00:00

abstract：:Our previous study [32] indicated that blockade of kappa-opioid receptors with nor-binaltorphimine (nor-BNI) in the medial preoptic area (MPOA) produced two different LH responses during midpregnancy in the rat: an increase in basal pulsatile LH secretion, followed in many cases by a larger and/or sustained increase i...

journal_title：Brain research

authors： Zhen S,Gallo RV

更新日期：1995-11-06 00:00:00

abstract：:Tyrosine hydroxylase phenotype expression was investigated in the catecholaminergic population of the locus coeruleus neurons of two pure inbred mouse strains, Balb/C and C57Black/6. Therefore, we have characterized the precise organization of tyrosine hydroxylase-expressing perikarya population, in control animals an...

journal_title：Brain research

authors： Ginovart N,Marcel D,Bezin L,Garcia C,Gagne C,Pujol JF,Weissmann D

更新日期：1996-05-20 00:00:00

abstract：:The petrosal ganglia contain the somata of the sensory fibers of the glossopharyngeal nerves, innervating structures of the tongue, pharynx, carotid sinus and carotid body. Petrosal ganglia were excised from adult cats and their neurons were dissociated and kept in tissue culture for 7-12 days. Intracellular recording...

journal_title：Brain research

authors： Varas R,Alcayaga J,Zapata P

更新日期：2000-11-03 00:00:00

abstract：:Hirschsprung's disease (HSCR) is a congenital malformation characterized by the absence of enteric ganglia in the distal intestine and gut obstruction. Some HSCR patients also have associated neurological symptoms. We studied a rat model of HSCR, also known as spotting lethal (sl/sl) rat, which carries a spontaneous d...

journal_title：Brain research

authors： Xie D,Croaker GDH,Li J,Song ZM

更新日期：2016-07-01 00:00:00

abstract：:Individuals are found to have better recall for self-referent information than other types of information. However, attribution research has shown that self-reference is highly correlated with emotional valence. The present study attempted to identify and separate the processing of self-reference and emotional valence...

journal_title：Brain research

authors： Watson LA,Dritschel B,Obonsawin MC,Jentzsch I

更新日期：2007-06-04 00:00:00

abstract：:The purpose of this study was to investigate autofluorescent pigment granules (lipofuscin, ceroid) in the trigeminal neurons (TN) during aging and streptozotocin-induced diabetes. Four young adult male rats were injected with streptozotocin (STZ; 50 mg/kg) to produce diabetes (DM), for comparison with four young uninj...

journal_title：Brain research

authors： Sugaya A,Sugimioto H,Mogi N,Tsujigami H,Deguchi S

更新日期：2004-02-27 00:00:00

abstract：:The present study was undertaken to examine the differential effect of estrogen (E) on the expression of tyrosine hydroxylase (TH) in the substantia nigra compacta (SNc) and in two subdivisions of the ventral tegmental area in ovariectomized (ovx) and ovx plus estradiol benzoate (ovx+E)-treated female rats. Cell count...

journal_title：Brain research

authors： Zsarnovszky A,Scalise TJ,Horvath TL,Naftolin F

更新日期：2000-06-23 00:00:00

abstract：:A microdialysis technique for the in vivo assessment of the monoaminergic and GABAergic levels in the ventromedial (VMN) and paraventricular nuclei (PVN) of the hypothalamus was used in order to examine the activities of neurons that project to the hypothalamic regions and are implicated in the regulation of ingestive...

journal_title：Brain research

authors： Ohtani N,Sugano T,Ohta M

更新日期：1999-09-18 00:00:00

abstract：:[125I]CGP 42112, first developed to identify angiotensin II receptor subtype 2 (AT2), was recently shown to bind to a novel non-angiotensin binding site in injured rat brain tissue. We addressed the question whether non-angiotensin [125I]CGP 42112 binding appears after kainic acid induced hippocampal neurodegeneration...

journal_title：Brain research

authors： Jöhren O,Viswanathan M,Saavedra JM

更新日期：1995-12-08 00:00:00

abstract：:Cultures of mouse spinal cord were used to visualize binding sites for [125I]angiotensin II (AII) by autoradiography. Visualization by light microscopy shows that neurones, but also glial cells possess angiotensin II binding sites which are located both on soma and processes. These findings open a new field of investi...

journal_title：Brain research

authors： Simonnet G,Legendre P,Laribi C,Allard M,Vincent JD

更新日期：1988-03-08 00:00:00

abstract：:We developed a rat spinal cord injury model and investigated whether endogenous endothelin (ET)-1 plays a role in astrocytic growth after injury. Immunohistochemical study showed that the number of immature astrocytes (ACs) exhibiting strong reactivity to the monoclonal antibody, RC1, markedly increased 24 h after the...

journal_title：Brain research

authors： Uesugi M,Kasuya Y,Hama H,Yamamoto M,Hayashi K,Masaki T,Goto K

更新日期：1996-07-29 00:00:00

abstract：:Hippocampal cholinergic neurostimulating peptide (HCNP), originally isolated from soluble fraction of young rat hippocampus and released from hippocampus by the stimulation of N-methyl-d-aspartate (NMDA) receptors, enhances the cholinergic phenotype development in vitro. HCNP precursor protein (HCNP-pp) has multiple f...

journal_title：Brain research

authors： Yamada K,Matsukawa N,Yuasa H,Hattori M,Nakazawa H,Borlongan CV,Ojika K

更新日期：2007-07-16 00:00:00

abstract：:We have investigated the role of NMDA receptors in the rat dorsal horn in mediating neuronal responses to noxious hindlimb ischemia, induced by acute occlusion of the femoral artery, as well as in the hyperalgesia evident when noxious mechanical stimuli were applied to the ischemic limb. Two specific NMDA antagonists,...

journal_title：Brain research

authors： Sher GD,Mitchell D

更新日期：1990-07-02 00:00:00

abstract：:The normal patterns of the occurrence of tryptophan, 5-hydroxytryptamine (5-HT), 5-hydroxyindoleacetic acid (5-HIAA) and monoamine oxidase (MAO) activity in chick brain during development were investigated. Tryptophan level in the brain on the 7th day of embryonic development was rather high and decreased gradually un...

journal_title：Brain research

authors： Suzuki O,Nagase F,Yagi

更新日期：1975-08-15 00:00:00

abstract：:Most functional neuroimaging techniques rely on activation-flow coupling (AFC) to detect changes in regional brain function, but AFC responses may also be altered during pathophysiological conditions such as ischemia. To define the relationship between progressive ischemia and the AFC response, graded levels of cerebr...

journal_title：Brain research

authors： Burnett MG,Detre JA,Greenberg JH

更新日期：2005-06-14 00:00:00

abstract：:When clonal rat pheochromocytoma PC12h cells were cultured in a 50% O2 atmosphere, cells gradually died during the cultivation. On the other hand, the addition of NGF at the final concentration of 50 ng/ml could rescue the cells from death. The culture in a 40% O2 atmosphere had little effect on the growth of PC12h ce...

journal_title：Brain research

authors： Enokido Y,Hatanaka H

更新日期：1990-12-17 00:00:00

abstract：:The present study examines age-related changes in the subcellular localization of cathepsin B (cath B) and cathepsin D (cath D), as well as morphological features of the cathepsin-immunoreactive (ir) neurons in rat cerebral cortex. Sprague-Dawley rats were studied at 3 and 26 months. By immunoelectron microscopy cath ...

journal_title：Brain research

authors： Jung H,Lee EY,Lee SI

更新日期：1999-10-09 00:00:00

abstract：:Sera from patients with multiple sclerosis (MS) frequently produce demyelination of central nervous system tissue cultures. The nature of the factors responsible for demyelination is not as yet clearly established. However, several authors previously reported, in in vivo and in vitro models, demyelinating activity in ...

journal_title：Brain research

authors： Grundke-Iqbal I,Bornstein MB

更新日期：1979-01-19 00:00:00