Abstract：
:These experiments examine the dependence of medial hypothalamic alpha 2-receptor binding on the availability of circulating glucose. Food deprivation and tolbutamide-induced hypoglycemia both diminished alpha 2-binding. These binding results were highly correlated with serum glucose levels. Prevention of tolbutamide hypoglycemia by concomitant injections of dextrose blocked the effects on alpha 2-binding. Injection of norepinephrine into the medial hypothalamic sites that normally elicit feeding behavior elevated serum glucose. These results suggest a homeostasis for control of glucose in a hypothalamic feeding system.
journal_name
Brain Resjournal_title
Brain researchauthors
Chafetz MD,Parko K,Diaz S,Leibowitz SFdoi
10.1016/0006-8993(86)91182-0subject
Has Abstractpub_date
1986-10-08 00:00:00pages
404-8issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)91182-0journal_volume
384pub_type
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