Effects of rat ventral and dorsal hippocampus temporal inactivation on delayed alternation task.

Abstract:

:To determine the involvement of the hippocampal regions in a operant-type delayed alternation task of short delay or long delay, microinjections of muscimol into the hippocampus were used for temporal inactivation during the behavioral test in each rat. Dorsal hippocampal inactivation impaired the correct ratio of long delay. Ventral hippocampal inactivation showed no changes in the correct ratio, however, it increased the tendency of perseveration in long delay. These findings suggest hippocampus has regional differentiation in delayed alternation task.

journal_name

Brain Res

journal_title

Brain research

authors

Maruki K,Izaki Y,Hori K,Nomura M,Yamauchi T

doi

10.1016/s0006-8993(01)02084-4

subject

Has Abstract

pub_date

2001-03-23 00:00:00

pages

273-6

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(01)02084-4

journal_volume

895

pub_type

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