VIP-like immunoreactivity in the anterior hypothalamic area of a hibernating bat varies with physiological state.

abstract：:The density of protein gene product 9.5- and tyrosine hydroxylase-immunoreactive nerve fibers innervating circumvallate papillae of the tongue was substantially increased in transgenic mice that overexpressed nerve growth factor (NGF) when compared with age-matched controls. The fiber density was age-dependent. Only t...

journal_title：Brain research

authors： Takami S,Getchell ML,Albers KM,Getchell TV

更新日期：1996-01-29 00:00:00

abstract：:The purpose of this study was to determine which myelinated cutaneous receptor populations in cat are responsive to a stimulus (cowhage) that produces unambiguous pruritus in human subjects. Initial experiments using electrocutaneous stimuli demonstrated that fibers conducting as slowly as 1.5 m/s could be recorded fr...

journal_title：Brain research

authors： Tuckett RP,Wei JY

更新日期：1987-06-09 00:00:00

abstract：:On the day of birth, female rats received either a thoraco-lumbar spinal transection or sham operation, followed by administration of either testosterone propionate (TP) or oil immediately after surgery and again on the third day of life. Upon sacrifice at 30 days of age examination of spinal cords revealed that TP ma...

journal_title：Brain research

authors： Fishman RB,Breedlove SM

更新日期：1985-12-01 00:00:00

abstract：:The VIIIth cranial nerve projections in the hagfish, which has only one circular canal in the ear, were studied by transganglionic HRP transport. This nerve has two branches, the nervus utricularis (N. utr.) and the nervus saccularis (N. sac.), each with its own ganglion, the ganglion utriculare (G. utr.) and the gang...

journal_title：Brain research

authors： Amemiya F,Kishida R,Goris RC,Onishi H,Kusunoki T

更新日期：1985-06-24 00:00:00

abstract：:Only recently, d-amino acids have been identified in mammals. Of these, d-serine has been most extensively studied. d-Serine was found to play an important role as a neurotransmitter in the human central nervous system (CNS) by binding to the N-methyl-d-aspartate receptor (NMDAr), similar to glycine. Therefore, d-seri...

journal_title：Brain research

authors： Fuchs SA,Berger R,de Koning TJ

更新日期：2011-07-15 00:00:00

abstract：:Repeated doses of estradiol benzoate (10 micrograms/kg, s.c., once a day for 2, 5 or 8 days) to male rats decreased gamma-aminobutyric acid (GABA) content and glutamate decarboxylase (GAD) activity in substantia nigra (SN) but failed to change these parameters in hippocampus, cerebral cortex, cerebellum, lateral septu...

journal_title：Brain research

authors： Nicoletti F,Meek JL

更新日期：1985-04-15 00:00:00

abstract：:Branches of the facial nerve were transected in newborn mice, resulting in paralysis of whisking of the mystacial vibrissae. After maturation, the brains were examined in Nissl preparations for alterations in the barrel field of the primary somatosensory cortex. There were no evident changes as a result of this interv...

journal_title：Brain research

authors： Rice FL

更新日期：1984-11-26 00:00:00

abstract：:Intracerebral injection of kainic acid (KA) in rat brain was previously found to cause altered immunohistochemical recognition of connexin-43 (Cx43) epitopes (epitope masking) with different sequence-specific antibodies against this gap junction protein. We demonstrate here that similar alterations occur when nitrocel...

journal_title：Brain research

authors： Sawchuk MA,Hossain MZ,Hertzberg EL,Nagy JI

更新日期：1995-06-12 00:00:00

abstract：BACKGROUND:Sex-specific trajectories in white matter development during adolescence may help explain cognitive and behavioral divergences between males and females. Knowledge of sex differences in typically developing adolescents can provide a basis for interpreting sexual dimorphisms in abilities and actions. METHOD:...

journal_title：Brain research

authors： Bava S,Boucquey V,Goldenberg D,Thayer RE,Ward M,Jacobus J,Tapert SF

更新日期：2011-02-23 00:00:00

abstract：:The central type benzodiazepine receptor (BDZr), an allosteric modulatory site of the GABAA receptor-anion channel, has been shown in vitro to respond to drugs with positive efficacy (agonists), zero efficacy (competitive antagonists) and drugs with negative efficacy (inverse agonists). However, this general concept o...

journal_title：Brain research

authors： Brouillet E,Chavoix C,Bottlaender M,Khalili-Varasteh M,Hantraye P,Fournier D,Dodd RH,Mazière M

更新日期：1991-08-23 00:00:00

abstract：:Chronic-intermittent hypoxia (CIH) was postulated to evoke c-fos expression in cortical regions that modulate sympathetic discharge. Animals exposed to CIH for 30 days exhibited c-fos labeling in medial prefrontal, cingulate, retrosplenial, and insular cortices. Our findings strongly suggest activation of cortical cir...

journal_title：Brain research

authors： Sica AL,Greenberg HE,Scharf SM,Ruggiero DA

更新日期：2000-07-07 00:00:00

abstract：:Neonatal rats were exposed to lead from parturition to weaning via the milk of dams drinking 0.2% lead acetate solution. The alterations of long-term potentiation (LTP) and paired-pulse facilitation (PPF) of hippocampal dentate gyrus in adult rats (90-115 days) following developmental lead exposure were studied in viv...

journal_title：Brain research

authors： Ruan DY,Chen JT,Zhao C,Xu YZ,Wang M,Zhao WF

更新日期：1998-09-28 00:00:00

abstract：:We recently reported that peripheral nerve injury produced by sciatic nerve transection induces a persistent increase in the expression of the immunoreactive Fos protein product of the c-fos proto-oncogene, an indicator of neuronal activity, in the lumbar spinal cord of the rat and that local anesthetic blockade of th...

journal_title：Brain research

authors： Chi SI,Levine JD,Basbaum AI

更新日期：1993-07-23 00:00:00

abstract：:Partial sciatic nerve ligation in mice caused a marked and persistent decrease in the latency of paw withdrawal from a thermal stimulus only on the ipsilateral side. This thermal hyperalgesia was abolished by repeated intrathecal pretreatment with a specific antibody to brain-derived neurotrophic factor (BDNF), but no...

journal_title：Brain research

authors： Yajima Y,Narita M,Narita M,Matsumoto N,Suzuki T

更新日期：2002-12-27 00:00:00

abstract：:In anaesthetized cats, medial gastrocnemius motor units (MUs) were stimulated with random sequences (mean rates between 6 and 12 pps) of electrical pulses delivered to their axons in small ventral root filaments. Muscle tension was recorded under isometric conditions, and spike trains of muscle spindle afferents were ...

journal_title：Brain research

authors： Christakos CN,Windhorst U

更新日期：1986-02-19 00:00:00

abstract：:Opiates and cannabinoids are among the most widely consumed habit-forming drugs in humans. Several studies have demonstrated the existence of interactions between both kind of drugs in a variety of effects and experimental models. The present study has been focused to determine whether perinatal delta9-tetrahydrocanna...

journal_title：Brain research

authors： Vela G,Martín S,García-Gil L,Crespo JA,Ruiz-Gayo M,Fernández-Ruiz JJ,García-Lecumberri C,Pélaprat D,Fuentes JA,Ramos JA,Ambrosio E

更新日期：1998-10-05 00:00:00

abstract：:The role of the central noradrenergic system in the supraoptic neuroendocrine regulation was investigated using slices of the guinea pig hypothalamus. Noradrenaline produced a complex membrane effect comprising two distinct depolarizations: one, associated with a moderate increase in input resistance and resulting in ...

journal_title：Brain research

authors： Ogata N,Matsuo T

更新日期：1986-10-15 00:00:00

abstract：:The hypothesis that protein kinase C activation can modulate excitatory amino acid-induced dopamine release was tested by investigating effects of phorbol esters, direct activators of protein kinase C, on dopamine release stimulated by N-methyl-D-aspartate (NMDA) and non-NMDA sub-types of excitatory amino acid agonist...

journal_title：Brain research

authors： Boksa P,Mount H,Chaudieu I

更新日期：1992-03-06 00:00:00

abstract：:The purpose of this review is to provide strategies and their rationale which can facilitate scientifically productive investigations into genetic, neuronal, brain functional and clinical aspects of bipolar disorder. The presentation addresses both factors that have impeded and those that have facilitated landmark adv...

journal_title：Brain research

authors： Bowden CL

更新日期：2008-10-15 00:00:00

abstract：:An object recognition task was used to determine if chronic restraint stress (6 h/day for 21 days) impairs non-spatial memory, since chronic restraint is known to impair spatial memory. In addition, food deprivation was tested as a possible modulating factor of any stress effect in this non-reward-dependent task. Foll...

journal_title：Brain research

authors： Beck KD,Luine VN

更新日期：1999-05-29 00:00:00

abstract：:We have previously found that the amyloid precursor protein (APP) of Alzheimer's disease is present on the surface of rat cortical neurons in culture, in a segmental pattern which first becomes evident after 24 hours and is fully developed by five days. As APP has previously been reported to have a short half-life in ...

journal_title：Brain research

authors： Storey E,Spurck T,Pickett-Heaps J,Beyreuther K,Masters CL

更新日期：1996-09-30 00:00:00

abstract：:(1)The brain stem of anaesthetized cats has been mapped between Horsley-Clark planes APO and P8.5 with electrical stimuli of low intensity in order to determine the areas which can produce excitatory of inhibitory influences on the spontaneously contracting, sympathetically denervated, urinary bladder. (2) Two inhibit...

journal_title：Brain research

authors： McMahon SB,Spillane K

更新日期：1982-02-25 00:00:00

abstract：:Brain capillaries form a selective interface, the blood-brain barrier (BBB), between the neural parenchyma and the blood. The factors which regulate this interface are poorly understood. Both the iris and retina possess vascular beds that express some BBB characteristics; therefore, they provide attractive models to f...

journal_title：Brain research

authors： Holash JA,Stewart PA

更新日期：1993-12-03 00:00:00

abstract：:We have previously shown that systemic administration of ondansetron, a selective serotonin type-3 (5-HT3) receptor antagonist, attenuates cholecystokinin (CCK)-induced suppression of food intake. The exact location of 5-HT3 receptors mediating this action is not clear and may involve hindbrain 5-HT3 receptors. In thi...

journal_title：Brain research

authors： Hayes MR,Covasa M

更新日期：2006-08-04 00:00:00

abstract：:The effects of retinoic acid (RA), a naturally occurring metabolite of vitamin A, on the growth, morphology and neurochemical differentiation of the PC12 clone of rat pheochromocytoma cells were investigated. RA added to the medium inhibited the growth of PC12 cells in a dose-dependent manner up to 10 microM without a...

journal_title：Brain research

authors： Matsuoka I,Mizuno N,Kurihara K

更新日期：1989-11-13 00:00:00

abstract：:Transforming growth factor alpha (TGF alpha) has been immunocytochemically localized in neuronal perikarya throughout the adult rat central nervous system (CNS). In order to determine if any TGF alpha-immunoreactive (TGF alpha-I) cell bodies have long axonal projections, indirect immunofluorescence was used in combina...

journal_title：Brain research

authors： Code RA,Seroogy KB,Fallon JH

更新日期：1987-09-22 00:00:00

abstract：:Hypophysiotropic thyrotropin-releasing hormone (TRH)-synthesizing neurons, the central regulators of the hypothalamic-pituitary-thyroid axis, are located in the paraventricular nucleus of the hypothalamus (PVN). These neurons are well-known to be stimulated by cold exposure through activation of ascending brainstem pa...

journal_title：Brain research

authors： Füzesi T,Wittmann G,Lechan RM,Liposits Z,Fekete C

更新日期：2009-10-19 00:00:00

abstract：:Chronic administration of caffeine (s.c. for a period of 14 days in escalating doses of 10-70 mg/kg) increased the sensitivity of rat cerebral cortical neurons to the inhibitory action of microiontophoretically applied adenosine. The sensitivity of spontaneously firing rat cerebral cortical neurons in caffeine-treated...

journal_title：Brain research

authors： Lin Y,Phillis JW

更新日期：1990-06-18 00:00:00

abstract：:Intraventricular injections of kainic acid were used to destroy the hippocampal CA3-CA4 cells, thus denervating the inner third of the molecular layer of the fascia dentata and stratum radiatum and stratum oriens of area CA1. The responses of intact afferents to such lesions were then examined histologically. The hipp...

journal_title：Brain research

authors： Nadler JV,Perry BW,Cotman CW

更新日期：1980-01-20 00:00:00

abstract：:Smoking is considered the leading cause of preventable death in the United States, but studies in animals suggest that nicotine is only weakly reinforcing. The maintenance of a dangerous habit by a weakly reinforcing agent has been the topic of some dispute. Using a two-lever "choice" self-administration procedure dev...

journal_title：Brain research

authors： Manzardo AM,Stein L,Belluzzi JD

更新日期：2002-01-04 00:00:00