An age-dependent novel hyperinnervation of circumvallate papillae by tyrosine hydroxylase-containing nerve fibers in NGF-overexpressing transgenic mice.

abstract：:Although norepinephrine-containing nerve terminals in the spinal cord synapse in the vicinity of sympathetic preganglionic cells, their effect on sympathetic outflow has remained unclear. Since survival during hypotension necessitates sustaining maximal sympathetic activity, we used experimental hypotension as a physi...

journal_title：Brain research

authors： Conlay LA,Maher TJ,Godley BF,Wurtman RJ

更新日期：1986-06-04 00:00:00

abstract：:The present in vitro study was performed to characterize neurons within dorsal regions of the nucleus tractus solitarii (NTS), principally at the level of area postrema, and known to receive inputs predominantly from cardiovascular and respiratory afferents (i.e. cardiorespiratory NTS). This report describes 4 classes...

journal_title：Brain research

authors： Paton JF,Foster WR,Schwaber JS

更新日期：1993-02-26 00:00:00

abstract：:We have found that daily subcutaneous injection with a maximum tolerated dose (MTD) of the mGluR2/3 agonist LY379268 (20mg/kg) beginning at 4 weeks dramatically improves the phenotype in R6/2 mice. For example, we observed normalization of motor function in distance traveled, speed, the infrequency of pauses, and the ...

journal_title：Brain research

authors： Reiner A,Wang HB,Del Mar N,Sakata K,Yoo W,Deng YP

更新日期：2012-09-14 00:00:00

abstract：:The effects of 17beta-estradiol (17betaE2) on spontaneous and excitatory amino acid (EAA) induced nucleus tractus solitarius (NTS) neuronal activity were investigated by electrophysiological and immunohistochemical experiments in ovariectomized female Sprague-Dawley rats. Out of 62 NTS neurons tested, 42 were inhibite...

journal_title：Brain research

authors： Xue B,Hay M

更新日期：2003-06-20 00:00:00

abstract：:Normal adult albino and Sprague-Dawley rats, under intraperitoneal Nembutal anesthesia, were used to demonstrate enzymatic activity in the choroid plexus and ventricular ependyma. The brain tissues were perfused or immersed with cold 2% glutaraldehyde and 8% sucrose in 0.1 M cacodylate buffer (pH 7.2-7.4) for 30 min a...

journal_title：Brain research

authors： Masuzawa T,Saito T,Sato F

更新日期：1981-10-19 00:00:00

abstract：:Antisera against rat-liver S-adenosylhomocysteine hydrolase (SAH-hydrolase) and calf intestinal mucosal adenosine deaminase (ADA) were raised in rabbits and subsequently used to determine the distribution of the corresponding enzymes in rat-brain using the peroxidase-antiperoxidase immunohistochemical procedure. SAH-h...

journal_title：Brain research

authors： Patel BT,Tudball N

更新日期：1986-04-09 00:00:00

abstract：:Adipose-derived stem cells (ASCs) are readily accessible multipotent mesenchymal stem cells and are known to secrete multiple growth factors, and thereby to have cytoprotective effects in various injury models. In the present study, the authors investigated the neuroprotective effect of ASCs in an intracerebral hemorr...

journal_title：Brain research

authors： Kim JM,Lee ST,Chu K,Jung KH,Song EC,Kim SJ,Sinn DI,Kim JH,Park DK,Kang KM,Hyung Hong N,Park HK,Won CH,Kim KH,Kim M,Kun Lee S,Roh JK

更新日期：2007-12-05 00:00:00

abstract：:We have previously described a rodent model of brief (30 min) middle cerebral artery occlusion followed by reperfusion, in which infarction develops gradually, reaching completion more than 3 days after ischemia, accompanied by morphological, biochemical, and pharmacological evidence of apoptosis. In the present study...

journal_title：Brain research

authors： Snider BJ,Du C,Wei L,Choi DW

更新日期：2001-11-02 00:00:00

abstract：:Neonatal hypoxia-ischemia (HI) has been extensively studied in a rat model characterized by unilateral brain damage (Rice-Vannucci Model). However, as well as in humans, each rat brain hemisphere is distinctly involved in cognitive functions, as for example retrieval of emotionally based memory, and neurochemical asym...

journal_title：Brain research

authors： Arteni NS,Salgueiro J,Torres I,Achaval M,Netto CA

更新日期：2003-05-30 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study analyzed whether administration of sulindac, a non-steroidal anti-inflammatory drug (NSAID) would prevent, attenuate or repair ischemia induced brain injury and reverse functional impairment in a focal ischemia model of stroke. METHODS:Male Sprague-Dawley rats (weight 250-300 g...

journal_title：Brain research

authors： Modi JP,Gharibani PM,Ma Z,Tao R,Menzie J,Prentice H,Wu JY

更新日期：2014-08-12 00:00:00

abstract：:There is evidence that acute exposure to kainic acid (KA) induces the release of endogenous ligands for opioid receptors and that mu-opioid agonists intensify KA-induced neurodegeneration. The aim of the present study was to investigate any acute toxic effects of KA upon mu-opioid receptors labelled with [3H]-DAMGO. 2...

journal_title：Brain research

authors： Ridd MJ,Fosbraey P,Kitchen I

更新日期：1998-12-14 00:00:00

abstract：:Histamine is one of the neurotransmitters suppressing appetite, but the interactions of histaminergic neurons with other neurons in satiety centers have not been clarified. Noradrenaline in the para-ventricular nucleus (PVN) has been shown to stimulate feeding. This study was designed to determine whether histamine mo...

journal_title：Brain research

authors： Kurose Y,Terashima Y

更新日期：1999-05-15 00:00:00

abstract：:Previous work has demonstrated that 3 pharmacologically and neuroanatomically distinct analgesia systems can be sequentially activated by increasing numbers of transcutaneous tail-shock. To date, the categorization of the early (after 2 tail-shocks) and late (after 80-100 tail-shocks) analgesias as opiate-mediated has...

journal_title：Brain research

authors： Watkins LR,Wiertelak EP,Maier SF

更新日期：1992-06-05 00:00:00

abstract：:The effect of chronic ethanol administration on the fine structure of the hippocampal CA1 stratum oriens was examined in two lines of mice selectively bred for their differential sensitivity to acute ethanol exposure (long-sleep, LS and short-sleep, SS mice). Two experiments were performed. In the first experiment, mi...

journal_title：Brain research

authors： Scheetz AJ,Markham JA,Fifková E

更新日期：1987-04-21 00:00:00

abstract：:Early brain injury (EBI) plays a pivotal role in the prognosis of patients with subarachnoid haemorrhage (SAH). Dexmedetomidine (DEX), a highly selective α2 receptor agonist, is reported to exert multiple protective effects in many neurological diseases. This study was designed to investigate whether DEX had neuroprot...

journal_title：Brain research

authors： Yin D,Zhou S,Xu X,Gao W,Li F,Ma Y,Sun D,Wu Y,Guo Q,Liu H,Han L,Wang Z,Wang Y,Zhang J

更新日期：2018-11-01 00:00:00

abstract：:Microinfusions of the benzodiazepine anxiolytic midazolam into the central or basolateral amygdaloid nuclei produced different anxiolytic effects in two tests of rat 'anxiety'. Infusions into the basolateral nucleus impaired open-arm avoidance in the elevated plus-maze test, but did not impair shock-probe avoidance in...

journal_title：Brain research

authors： Pesold C,Treit D

更新日期：1995-02-13 00:00:00

abstract：:The impact of hyperglycemia after traumatic brain injury (TBI), and even the administration of glucose-containing solutions to head injured patients, remains controversial. In the current study adult male Sprague-Dawley rats were tested on behavioral tasks and then underwent surgery to induce sham injury or unilateral...

journal_title：Brain research

authors： Shijo K,Ghavim S,Harris NG,Hovda DA,Sutton RL

更新日期：2015-07-21 00:00:00

abstract：:A classification of the parietal corticofugal neurons was performed in cats under Nembutal anesthesia. Eighty-eight neurons were identified with antidromic activation by the pontine stimulation. Thirteen neurons were furthermore identified with intracellular HRP staining. In these neurons, we found the close correlati...

journal_title：Brain research

authors： Samejima A,Yamamoto T,Ito J,Oka H

更新日期：1985-11-11 00:00:00

abstract：:Three experiments were conducted to test the hypothesis that brain corticotropin-releasing hormone (CRH) systems mediate stress-induced freezing behavior, an index of a rat's level of fear. We administered i.c.v. 0-50 micrograms of alpha-helical CRH9-41 (a specific CRH antagonist) before foot shock and showed that thi...

journal_title：Brain research

authors： Kalin NH,Sherman JE,Takahashi LK

更新日期：1988-08-02 00:00:00

abstract：:In the adult rabbit, the somatostatin-immunoreactive neurons are seen in all visual cortical layers, with the majority of them being found in layers II-III, V and VI. During postnatal development, we can see labeled cells in layer VI at birth and in layers V and VI on the 3rd day. The labeled cells are seen in layers ...

journal_title：Brain research

authors： Ramón y Cajal-Agüeras S,Contamina P,Parra P,Martinez-Millán L,De Carlos JA,Ramo C

更新日期：1985-12-16 00:00:00

abstract：:By using the modified detection method, favored patterns can be detected in a total of 44 spontaneous spike trains. Among these the 'periodical burst' discharge of one sympathetic preganglionic neuron and the 'fast-slow' alternative discharge of some hypothalamic neurons have visible characteristics, hence we use them...

journal_title：Brain research

authors： Ku YH,Wang XQ

更新日期：1991-09-20 00:00:00

abstract：:Our previous single unit and ultrastructural studies of visual cortex of dark-reared rats revealed an impairment of intracortical inhibitory mechanisms [2,3,5]. Neurochemical changes in inhibitory neurotransmitter and/or neuropeptides, such as gamma-aminobutyric acid (GABA) and somatostatin (SS), respectively, may con...

journal_title：Brain research

authors： Benevento LA,Bakkum BW,Cohen RS

更新日期：1995-08-21 00:00:00

abstract：:In the present study, we investigated the co-localization pattern of the delta subunit with other subunits of GABA(A) receptors in the rat brain using immunoprecipitation and Western blotting techniques. Furthermore, we investigated whether low concentrations of ethanol affect the delta-subunit-containing GABA(A) rece...

journal_title：Brain research

authors： Mehta AK,Marutha Ravindran CR,Ticku MK

更新日期：2007-08-24 00:00:00

abstract：:Bilateral intranigral administration of the selective NK-1 tachykinin receptor agonist [AcArg6, Sar9, Met(O2)11]SP6-11 (0-1 nmol total bilateral dose) selectively induced grooming in rats. This response was blocked by concurrent intranigral administration of the NK-1 tachykinin receptor antagonist RP 67580 (2 nmol), b...

journal_title：Brain research

authors： Stoessl AJ,Brackstone M,Rajakumar N,Gibson CJ

更新日期：1995-11-27 00:00:00

abstract：:Interactive-activation models posit that visual word recognition involves co-activation of orthographic neighbors (e.g., note, node) and competition among them via lateral inhibitory connections. Behavioral evidence of this lexical competition comes from masked priming paradigms, in which target words elicit slower re...

journal_title：Brain research

authors： Meade G,Grainger J,Midgley KJ,Emmorey K,Holcomb PJ

更新日期：2018-04-15 00:00:00

abstract：:Focal adhesion kinase (FAK) and proline-rich tyrosine kinase (PYK2) are two related non-receptor tyrosine kinases which are thought to play a role in transducing extracellular matrix (ECM)-derived survival signals into cells. The functions of FAK and PYK2 are linked to autophosphorylation of their specific tyrosine re...

journal_title：Brain research

authors： Ziemka-Nalecz M,Jaworska J,Sypecka J,Zalewska T

更新日期：2015-05-05 00:00:00

abstract：:Temporo-nasal asymmetry in visual responses has been observed in many behavioural studies. These observations have typically been attributed to the anatomical asymmetry of fibres projecting to the Superior Colliculus (SC), even though this attribution is debated. The present study investigates temporo-nasal asymmetry ...

journal_title：Brain research

authors： Bertini C,Leo F,Làdavas E

更新日期：2008-11-25 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by upper and lower motor neuron death with ascending paralysis leading to death. In a transgenic mouse model of ALS (SOD1-G93A) weakness appears at 3 months of age, and because of progressive paralysis leads to death by 5 months. Cyclospo...

journal_title：Brain research

authors： Keep M,Elmér E,Fong KS,Csiszar K

更新日期：2001-03-16 00:00:00

abstract：:Marmoset monkeys (Callithrix jacchus) with bilateral transections of the anterior temporal stem, amygdala and fornix were unable to relearn a 2-choice object discrimination first learnt prior to surgery, and were very severely impaired at relearning a concurrent object discrimination task which they had learnt and rel...

journal_title：Brain research

authors： Maclean CJ,Gaffan D,Baker HF,Ridley RM

更新日期：2001-01-05 00:00:00

abstract：:Using the teased fiber recording method, we have compared pathophysiological properties of afferent axons injured in the infraorbital nerve (ION) vs the sciatic nerve in rats. Both myelinated and unmyelinated axons ending in ION neuromas produced much less ongoing discharge than those ending in sciatic nerve neuromas....

journal_title：Brain research

authors： Tal M,Devor M

更新日期：1992-05-01 00:00:00