Calcitonin gene-related peptide projection from the ventromedial thalamic nucleus to the insular cortex: a combined retrograde transport and immunocytochemical study.

Abstract:

:We employed a highly sensitive combination method of retrograde tracing and immunohistochemistry to identify calcitonin gene-related peptide (CGRP)-containing fiber pathways in the rat from the ventrolateral part of the ventrolateral thalamic nucleus (vl-vl) and the caudal continuation to the insular cortex. Biotin-wheat germ agglutinin (B-WGA) injected into the insular cortex labeled numerous neurons in the vl-vl and the caudal continuation ipsilaterally; simultaneous staining with CGRP antiserum revealed that some of these neurons are CGRP positive.

journal_name

Brain Res

journal_title

Brain research

authors

Shimada S,Shiosaka S,Hillyard CJ,Girgis SI,MacIntyre I,Emson PC,Tohyama M

doi

10.1016/0006-8993(85)91211-9

subject

Has Abstract

pub_date

1985-09-30 00:00:00

pages

200-4

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(85)91211-9

journal_volume

344

pub_type

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