Abstract：
:Sustained seizure activity can be induced in rabbit olfactory bulb by application of brief low-level current via chronically implanted micro-electrodes. Sensitivity to such stimulation is markedly augmented by prior surgical isolation of the ipsilateral or contralateral bulb. The isolated rabbit olfactory bulb apparently possesses an intrinsic system sufficient to acquire and retain altered neuronal excitability of an epileptiform kind. The preparation described here offers promise as a model for further studies of electrophysiological plasticity in a simple cortical system.
journal_name
Brain Resjournal_title
Brain researchauthors
Deluca AM,Chorover SLdoi
10.1016/0006-8993(75)90056-6subject
Has Abstractpub_date
1975-08-29 00:00:00pages
185-97issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(75)90056-6journal_volume
94pub_type
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