Abstract:
:Axotomy produced an increase in the spike width and a decrease in amplitude of the afterhyperpolarization which followed the action potential in C-cells of bullfrog sympathetic ganglia. Although no change in B-cell conduction velocity was noted, C-cell conduction velocity increased significantly and approached that of B-cells. This change may reflect a process of dedifferentiation prior to the initiation of regrowth following axotomy.
journal_name
Brain Resjournal_title
Brain researchauthors
Shapiro J,Gurtu S,Gordon T,Smith PAdoi
10.1016/s0006-8993(87)80044-6subject
Has Abstractpub_date
1987-04-28 00:00:00pages
186-8issue
1eissn
0006-8993issn
1872-6240pii
S0006-8993(87)80044-6journal_volume
410pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The distribution of cortical neurons which project to the spinal cord was investigated in the developing and adult rat using the retrograde transport of horseradish peroxidase (HRP). Following injections of HRP into the cervical spinal cord of a postnatal day 4 rat, retrogradely labeled neurons are located in layer Vb...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(84)90161-5
更新日期:1984-04-01 00:00:00
abstract::Mouse brain expresses three principal glucose transporters. Glut1 is an endothelial marker and is the principal glucose transporter of the blood-brain barrier. Glut3 and Glut6 are expressed in glial cells and neural cells. A mouse line with a null allele for Glut3 has been developed. The Glut3(-/-) genotype is intraut...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.02.014
更新日期:2011-04-12 00:00:00
abstract::An in vitro method has been developed to determine quantitatively the permeability of the perineurium to radiotracers at room temperature. The permeability to [14C]sucrose of the isolated perineurium of the sciatic nerve of the frog, Rana pipiens, was measured at rest length, when the perineurium was stretched and aft...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90244-0
更新日期:1979-09-21 00:00:00
abstract::Administration of sheep red blood cells (10(6) cells, i.p.) resulted in central norepinephrine (NE) and dopamine (DA) changes which corresponded with the time of the peak immune response. These amine variations, however, appeared to be specific to certain brain regions. The increased accumulation of the NE metabolite,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90117-e
更新日期:1991-08-23 00:00:00
abstract::Aspartate-immunoreactivity (ir) was examined in the mouse trigeminal ganglion (TG). The ir was detected in 34% of TG neurons and their cell bodies were of various sizes (mean +/- S.D. = 1,234 +/- 543 microm(2)). A triple immunofluorescence method revealed the co-expression of aspartate with calcitonin gene-related pep...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.01.092
更新日期:2006-04-12 00:00:00
abstract:BACKGROUND:Irritable Bowel Syndrome (IBS) is a common functional gastrointestinal disorder which is characterized by altered bowel habits. A growing number of studies investigate the association between IBS and cognitive impairments. Current studies report conflicting results regarding cognitive impairment in IBS patie...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.05.036
更新日期:2019-09-15 00:00:00
abstract::Microinfusions of the benzodiazepine anxiolytic midazolam into the central or basolateral amygdaloid nuclei produced different anxiolytic effects in two tests of rat 'anxiety'. Infusions into the basolateral nucleus impaired open-arm avoidance in the elevated plus-maze test, but did not impair shock-probe avoidance in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01318-c
更新日期:1995-02-13 00:00:00
abstract::MicroRNAs (miRNAs) are a class of non-coding small RNAs that regulate the expression of target genes. They derive from pre-miRNAs that are enzymatically processed by dicer to ∼22 nucleotide mature miRNAs. Members of the pre-miRNA lethal-7 (let-7) are known to regulate cell proliferation and apoptosis. Here, we showed ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.01.032
更新日期:2018-04-15 00:00:00
abstract::Opioid-binding cell adhesion molecule (OBCAM) is the member of the IgLON family, a subgroup of the immunoglobulin superfamily. In the present study, the functions and dynamics of OBCAM were investigated in hippocampal neurons in vitro. Western blotting revealed that OBCAM expression was low at early stages of culture ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.04.062
更新日期:2007-08-24 00:00:00
abstract::By means of an immunohistochemical technique, we examined the neuronal induction of 72-kDa heat shock protein (HSP72) in response to methamphetamine-induced hyperthermia in the mouse hippocampus. Strong HSP72 immunoreactivity (ir) was found in the neurons of hippocampus proper, particularly in the CA1/2 and medical CA...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90602-j
更新日期:1993-10-29 00:00:00
abstract::The nigrostriatal projection was studied with a retrograde tracing method (Evans blue, EB) combined with a technique for dopamine histofluorescence. The study, realized in control rats and in animals with 6-hydroxydopamine-induced lesions of the dopaminergic pathway, yielded the following results. (1) In 3 control rat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90235-3
更新日期:1981-06-01 00:00:00
abstract::Hypoxia-induced apoptosis of retinal ganglion cells (RGCs) is the major cause of progressive vision loss in numerous retinal diseases, including glaucoma and diabetic retinopathy. Taurine is a naturally occurring free amino acid that has been shown to have neurotrophic and neuroprotective properties in the retina. We ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.04.054
更新日期:2009-07-07 00:00:00
abstract::The density of protein gene product 9.5- and tyrosine hydroxylase-immunoreactive nerve fibers innervating circumvallate papillae of the tongue was substantially increased in transgenic mice that overexpressed nerve growth factor (NGF) when compared with age-matched controls. The fiber density was age-dependent. Only t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01336-9
更新日期:1996-01-29 00:00:00
abstract::Catecholamine concentrations were determined at central and peripheral level in high blood pressure (HBP), low blood pressure (LBP) and random bred (RB) mice. In HBP mice compared to LBP, the noradrenaline concentration was lower in the locus coeruleus, medullary A1-C1 and A2-C2 areas, thoracic spinal cord, posteroven...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90784-x
更新日期:1985-08-05 00:00:00
abstract::This study examines projection to the cerebellar flocculus of eye movement-related neurons in the median and paramedian part of the cat pontine tegmentum between the trochlear and the abducens nucleus. They were identified by rhythmic activity related to horizontal vestibular nystagmus induced by sinusoidal rotation. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90465-5
更新日期:1980-02-10 00:00:00
abstract::Protease-activated receptors (PARs), G-protein-coupled receptors, are widely expressed in various tissues, where they participate in physiological and pathological processes, such as hemostasis, proliferation, tissue repair, and inflammation. Recently, we found that PARs were upregulated in the rat retina following op...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.04.040
更新日期:2005-06-21 00:00:00
abstract::Confocal microscopy and the Ca(2+)-sensitive fluorescent dye fluo-3 were used to study subcellular Ca2+ signals in embryonic, neonatal, and adult dorsal root ganglion (DRG) neurons in excised dorsal root ganglia. Optical images obtained from isolated whole embryonic and neonatal ganglia revealed a marked variability i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91444-3
更新日期:1994-01-28 00:00:00
abstract::The identification of biologically important and chemically well-defined substances that can promote axon and dendrite formation would improve present understanding of the development of the nervous system. Physiological concentrations of insulin and insulin-like growth factor-II (IGF-II) reversibly enhanced neurite o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90246-4
更新日期:1984-06-08 00:00:00
abstract::A commissural-associational entorhino-entorhinal projection in the guinea pig was analyzed using anterograde and retrograde axonal tracing techniques. The projection originated in layer II and terminated in layer Ia of both the medial entorhinal area (MEA) and the lateral entorhinal area (LEA). A few cells in other la...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90117-0
更新日期:1989-12-25 00:00:00
abstract::The present study was designed to investigate the distribution of serotonin 5-HT1A receptor protein (5-HT1A-immunoreactivity) and its localization within cortical pyramidal neurons of the rat cingulate cortex. This experimental direction was inspired by recent data showing the role of 5-HT1A receptors in the pathology...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)03352-3
更新日期:2003-10-31 00:00:00
abstract::Basal sleep amounts in adrenalectomized rats (AdX), as compared to intact animals, exhibit a significant increase in slow-wave sleep (SWS), a tendency towards an increase in paradoxical sleep (PS), and circadian rhythms (SWS and PS) flattened in amplitude. An immobilization stress (IS) of 1 h, imposed on AdX rats at t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)02313-6
更新日期:2000-01-24 00:00:00
abstract::We studied whether K+, a potent cerebrovasodilator released by active neurons, participates in the increase in cortical cerebral blood flow (CBF) elicited by stimulation of the cerebellar fastigial nucleus (FN). Rats were anesthetized by continuous administration of halothane (1-3%), paralyzed and artificially ventila...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91544-b
更新日期:1991-11-01 00:00:00
abstract::Recordings were made from single neurons in the rat's central nucleus of the inferior colliculus (ICc). Binaural responses were studied when dichotic tone bursts with various interaural-level differences were presented simultaneously or with a contralateral delay. These dichotic tone bursts allowed us to probe tempora...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.09.059
更新日期:2009-12-15 00:00:00
abstract::We have previously reported the first successful production of monoclonal antibodies against the cholinergic neuronal marker, choline acetyltransferase (ChAT). We now report some inter-and intraspecies cross-reactivity studies of the monoclonal antibody AB1. This antibody reacted most strongly with bovine ChAT and wea...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90889-7
更新日期:1982-02-25 00:00:00
abstract::During the early postnatal development of the rat large numbers of pyramidal tract neurons are present in layer V of the occipital cortex, but by the end of the third postnatal week the distribution of pyramidal tract neurons becomes restricted to the more rostral cortical areas. This restriction is brought about by s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90661-4
更新日期:1985-06-17 00:00:00
abstract::The effects of alpha-bungarotoxin from Bungarus multicinctus and Bungarus caeruleus were studied on three types of cholinergic response in Aplysia central neurones. These responses are the result of three distinct changes in ionic permeability: selective increases in permeabiliyt to Na, Cl and K, respectively. It was ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90142-6
更新日期:1976-05-14 00:00:00
abstract::We have developed a novel imaging system "real-time bioradiography", which is able to estimate the dynamic changes of physiological function and metabolism in living tissues using positron emitter-labeled tracers and chemiluminescence probes. The apparatus is comprised of a photon-counting camera, image-controller, cu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.11.034
更新日期:2006-03-10 00:00:00
abstract::The organization and representation of conceptual knowledge in the brain remains a controversial issue in terms of both neuropsychological and imaging evidence. We report the results of a functional magnetic resonance study in which the role of the most debated dimensions (domain and feature type) was evaluated throug...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.11.070
更新日期:2008-02-15 00:00:00
abstract::The postnasal development of the Na-independent [3H]glutamate binding sites, which exhibit some characteristics of postsynaptic glutamate receptors, has been studied in rat hippocampal membranes. The amount of binding sites (expressed in pmol/hippocampus) represents 4% of the adult level at postnatal day (PND) 4, incr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(81)90092-4
更新日期:1981-01-01 00:00:00
abstract::Solid pieces of the fetal septal region (SG) or hippocampus (HPC) were implanted in a cavity formed by aspiration of the fimbria fornix (FF) and the overlying cingulate cortex on one side in adult rats. In other lesioned animals cell suspensions obtained from the fetal septal area (SS) or the locus coeruleus region of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90632-9
更新日期:1987-01-06 00:00:00