On the relation between cerebral cysteinyl-leukotriene formation and epileptic seizures.

abstract：:The density of protein gene product 9.5- and tyrosine hydroxylase-immunoreactive nerve fibers innervating circumvallate papillae of the tongue was substantially increased in transgenic mice that overexpressed nerve growth factor (NGF) when compared with age-matched controls. The fiber density was age-dependent. Only t...

journal_title：Brain research

authors： Takami S,Getchell ML,Albers KM,Getchell TV

更新日期：1996-01-29 00:00:00

abstract：:Dehydroepiandrosterone (DHEA) modulates neurogenesis, neuronal function, neuronal survival and metabolism, enhancing mitochondrial oxidative capacity. Glucose deprivation and hypometabolism have been implicated in the mechanisms that mediate neuronal damage in neurological disorders, and some studies have shown that t...

journal_title：Brain research

authors： Vieira-Marques C,Arbo BD,Ruiz-Palmero I,Ortiz-Rodriguez A,Ghorbanpoor S,Kucharski LC,Arevalo MA,Garcia-Segura LM,Ribeiro MF

更新日期：2016-08-01 00:00:00

abstract：:Following single injections of horseradish peroxidase (HRP) in the superior colliculus (SC) and [3H]proline in the striate cortex of rats, a close correspondence was observed in the topographical arrangements of extrastriate cortical fields of HRP retrograde label and of isotope anterograde label. These results suppor...

journal_title：Brain research

authors： Olavarria J,Van Sluyters RC

更新日期：1982-06-24 00:00:00

abstract：:The distribution of antidiabetic sulfonylurea [( 3H]glibenclamide) binding sites is heterogeneous in rat brain. Pyramidal and extrapyramidal motor system contain the highest densities of sites, particularly in the substantia nigra and in the globus pallidus. Only low levels are present in the hypothalamic nuclei and t...

journal_title：Brain research

authors： Mourre C,Ben Ari Y,Bernardi H,Fosset M,Lazdunski M

更新日期：1989-05-01 00:00:00

abstract：:The ability to adapt a variety of motor acts to compensate for persistent natural or artificially induced errors in movement accuracy requires the cerebellum. For adaptation of the rapid shifts in the direction of gaze called saccades, the oculomotor vermis (OMV) of the cerebellum must be intact. We disrupted the neur...

journal_title：Brain research

authors： Kojima Y,Soetedjo R,Fuchs AF

更新日期：2011-07-15 00:00:00

abstract：:Data are presented which show that background electric activity of the human brain is reduced by visual stimulation. Occipital EEG amplitude decreases 5-15% for all frequencies analyzed (0.2-40 Hz) upon pattern stimulation. The reduction is stimulus-specific, i.e. is the strongest for stimuli that activate a large num...

journal_title：Brain research

authors： Vijn PC,van Dijk BW,Spekreijse H

更新日期：1991-05-31 00:00:00

abstract：:Rapid skin indentations can produce strong tap-like sensations that contain little information about skin indentation depth. Although slower stimuli produce weaker sensations, subjects can more accurately identify how the position of the skin surface changes with respect to the deeper tissues. This dissociation betwee...

journal_title：Brain research

authors： Horch KW,Tuckett RP,Burgess PR

更新日期：1984-09-10 00:00:00

abstract：:Anesthetized Sprague-Dawley rats fitted with intracerebroventricular (i.c.v.) cannulas were infused with one of the aminopeptidase inhibitors, amastatin or bestatin, over a 5-min period. After infusion, 1-2 X 10(6) cpm of [125I]angiotensin II ([125I]AII) or [125I]angiotensin III ([125I]AIII) was injected through the s...

journal_title：Brain research

authors： Dewey AL,Wright JW,Hanesworth JM,Harding JW

更新日期：1988-05-17 00:00:00

abstract：:The effects of the serotonin precursor 5-HTP, were determined in a behavioral DNIC paradigm (increase in vocalization threshold after intraperitoneal injection of the algogenic agent, phenylbenzoquinone). This counter-irritation phenomenon was strongly potentiated by 5-HTP, such potentiation being blocked by the 5-HT ...

journal_title：Brain research

authors： Kraus E,Besson JM,Le Bars D

更新日期：1982-01-14 00:00:00

abstract：:The object of this study was to quantify and compare the degree of control monkeys may assert over firing patterns of normal and epileptic neurons. Thirty-seven epileptic and 70 normal neurons were studied in detail. The operant task was for the monkey to generate specified consecutive interspike intervals (ISI). The ...

journal_title：Brain research

authors： Wyler AR,Finch CA,Burchiel KJ

更新日期：1978-08-04 00:00:00

abstract：:We have shown earlier that nicotinic agonists induce the release of noradrenaline from chick sympathetic neurons in culture in two ways: (a) by activating the postsynaptic nicotinic receptors on nerve cell bodies, giving rise to spreading electrical activity and opening of voltage operated calcium channels in neuronal...

journal_title：Brain research

authors： Dolezal V,Lee K,Schobert A,Hertting G

更新日期：1996-11-18 00:00:00

abstract：:Early environmental factors can modulate the development of the hypothalamic-pituitary-adrenal (HPA) axis response to stress, together with subsequent brain functions and emotional behaviors. Two rat strains, Sprague-Dawley (SD) and Fischer 344 (F344), are known to exhibit differences in HPA axis reactivity and anxiet...

journal_title：Brain research

authors： Uchida S,Hara K,Kobayashi A,Otsuki K,Hobara T,Yamagata H,Watanabe Y

更新日期：2010-02-26 00:00:00

abstract：:Stereotaxic microinjections of the excitotoxin, ibotenic acid, were made into the striatum, hippocampus or cerebellum of the immature (7-day-old) rat. Two days later, pups were decapitated and the brains processed for light microscopic examination or neurochemical analyses. 10 micrograms ibotenate caused a complete lo...

journal_title：Brain research

authors： Steiner HX,McBean GJ,Köhler C,Roberts PJ,Schwarcz R

更新日期：1984-07-30 00:00:00

abstract：:Converging evidence suggests that compromised motor abilities in hemiparetic cerebral palsy are not solely due to impairments in motor execution, but are also related to deficits in action planning. The present study had two aims. First, we compared grip planning in a sequential task between participants with left-sid...

journal_title：Brain research

authors： Crajé C,van der Kamp J,Steenbergen B

更新日期：2009-03-19 00:00:00

abstract：:We previously reported that aquaporin 4 (AQP4) played a critical role in formation of brain edema and the altered expression of dystroglycan (DG) could relate with AQP4 expression after traumatic brain injury (TBI). However the mechanisms of this process remain unclear. DG was showed could act as a scaffold involved i...

journal_title：Brain research

authors： Zhang G,Ma P,Wan S,Xu J,Yang M,Qiu G,Zhuo F,Xu S,Huo J,Ju Y,Liu H

更新日期：2019-10-15 00:00:00

abstract：:5-Hydroxytryptamine (5-HT, serotonin), synthesized in midbrain raphe nuclei and released in various hypothalamic sites, decreases food intake but the specific 5-HT receptor subtypes involved are controversial. Here, we have studied changes in the regional density of binding to 5-HT receptors and transporters and the l...

journal_title：Brain research

authors： Park S,Harrold JA,Widdowson PS,Williams G

更新日期：1999-11-13 00:00:00

abstract：:The 2009 influenza A(H1N1) pandemic led to a particularly high risk of morbidity and mortality among pregnant women. Therefore, inactivated influenza vaccines have been widely recommended for women in any period of gestation. Recent studies have shown that the peripheral adaptive immune system plays an important role ...

journal_title：Brain research

authors： Xia Y,Qi F,Zou J,Yao Z

更新日期：2014-12-10 00:00:00

abstract：:Transplanted embryonic stem (ES) cells can be integrated into the retinas of adult mice as well-differentiated neuronal cells. However, the integrated ES cells also have a tumorigenic effect just because they have the ability for multipotential differentiation to various types of tissues. Thus, control of neoplastic p...

journal_title：Brain research

authors： Hara A,Niwa M,Kumada M,Aoki H,Kunisada T,Oyama T,Yamamoto T,Kozawa O,Mori H

更新日期：2006-04-26 00:00:00

abstract：:Immunohistochemistry was used to examine the co-occurrence of nicotinic acetylcholine receptor subunits with calcium-binding proteins in ganglion cells of the chick retina. The alpha3 subunit was rarely observed in ganglion cells containing calbindin, calretinin, or parvalbumin. On the other hand, the alpha8 subunit w...

journal_title：Brain research

authors： Araki CM,Pires RS,Britto LR,Lindstrom JM,Karten HJ,Hamassaki-Britto DE

更新日期：1997-11-07 00:00:00

abstract：:Cannabinoids are promising therapies to support neurogenesis and decelerate disease progression in neuroinflammatory and degenerative disorders. Whether neuroprotective effects of cannabinoids are sustainable during persistent viral infection of the CNS is not known. Using a rodent model of chronic viral encephalitis ...

journal_title：Brain research

authors： Solbrig MV,Fan Y,Hazelton P

更新日期：2013-11-06 00:00:00

abstract：:The DNA content and activity of acid and alkaline deoxyribonucleases (DNases) were measured through age 60 days in the hypothalamus of female rats injected s.c. with 1.25 mg testosterone propionate 48 h after birth. DNA significantly increases through age 60 days, however, androgenization does not affect the DNases or...

journal_title：Brain research

authors： Litteria M

更新日期：1985-02-01 00:00:00

abstract：:The effects of the dopamine transporter (DAT) inhibitors cocaine and GBR12909 on DAT and dopamine D(2) receptors were evaluated in the brains under awake and isoflurane-anesthetized monkeys using high-resolution positron emission tomography (PET) in combination with microdialysis. The striatal DAT availability and dop...

journal_title：Brain research

authors： Tsukada H,Nishiyama S,Kakiuchi T,Ohba H,Sato K,Harada N,Nakanishi S

更新日期：1999-12-04 00:00:00

abstract：:Our recent researches have identified increased expression of miR-21-5p in rats brain following traumatic brain injury (TBI), which protected against blood-brain barrier (BBB) damage. To further study the mechanism underlying the role of miR-21-5p on alleviating BBB damage after TBI, we performed the scratch injury mo...

journal_title：Brain research

authors： Ge X,Huang S,Gao H,Han Z,Chen F,Zhang S,Wang Z,Kang C,Jiang R,Yue S,Lei P,Zhang J

更新日期：2016-11-01 00:00:00

abstract：:The transcription factor cAMP responsive element binding protein (CREB) is important in regulating immediate-early genes and some late-effector genes involved in neuroplasticity in response to peripheral injury and stressful insults. Partial nerve injury elicited neuropathic pain is accompanied by increased phosphoryl...

journal_title：Brain research

authors： Ma W,Hatzis C,Eisenach JC

更新日期：2003-10-24 00:00:00

abstract：:The effects of intracerebroventricular administration of 6-hydroxydopamine (6-OHDA) and 5,7-dihydroxytryptamine (5,7-DHT) on sodium-sensitive [3H]mazindol binding were investigated in the rat hypothalamus and corpus striatum. In the hypothalamus, specific [3H]mazindol binding was inhibited by low concentrations of sod...

journal_title：Brain research

authors： Angel I,Janowsky A,Paul SM

更新日期：1989-12-04 00:00:00

abstract：:Serial ion-exchange and high-performance liquid chromatography separations were employed for the tissue extraction and purification of kynurenic acid (KYNA). Subsequently, the compound isolated from postmortem human brain tissue was unequivocally identified as KYNA by nuclear magnetic resonance and mass spectrometric ...

journal_title：Brain research

authors： Turski WA,Nakamura M,Todd WP,Carpenter BK,Whetsell WO Jr,Schwarcz R

更新日期：1988-06-28 00:00:00

abstract：:Previous electrophysiological as well as imaging research has contributed to the understanding of impairments in attention, executive functions, and memory in patients with attention-deficit/hyperactivity disorder (ADHD). However, there is a lack of studies investigating ADHD related differences in the gamma range of ...

journal_title：Brain research

authors： Lenz D,Krauel K,Schadow J,Baving L,Duzel E,Herrmann CS

更新日期：2008-10-15 00:00:00

abstract：:In the brain, nitric oxide (NO) has been identified as a messenger molecule and a mediator of excitatory amino acid-induced neurotoxicity. In this study, the effects of NO on serum-induced mitogenesis and cell proliferation of the cerebellar glial cells were assessed. NO-generating agent, S-nitroso-N-acetylpenicillami...

journal_title：Brain research

authors： Garg UC,Devi L,Turndorf H,Goldfrank LR,Bansinath M

更新日期：1992-10-02 00:00:00

abstract：:A cluster of trigeminal nociceptive neurons was located in the lateral sulcus on the upper bank of the frontoparietal operculum in a region bordering between cortical areas SII and 7b. These neurons were isolated in cortical cell layers IV and V-VI. All nociceptive neurons responded exclusively to noxious mechanical s...

journal_title：Brain research

authors： Dong WK,Salonen LD,Kawakami Y,Shiwaku T,Kaukoranta EM,Martin RF

更新日期：1989-04-10 00:00:00

abstract：:The distribution of calretinin containing neurons examined by in situ hybridization mapping was compared with that obtained by immunocytochemistry in the brain of octopus. Results revealed a close correspondence between the two types of investigations. Western blot analysis disclosed a 29 kDa protein immunostained wit...

journal_title：Brain research

authors： Altobelli GG,Cimini V

更新日期：2007-02-09 00:00:00