Abstract:
:The effects of the serotonin precursor 5-HTP, were determined in a behavioral DNIC paradigm (increase in vocalization threshold after intraperitoneal injection of the algogenic agent, phenylbenzoquinone). This counter-irritation phenomenon was strongly potentiated by 5-HTP, such potentiation being blocked by the 5-HT receptor blocker, cinanserin. These results are in keeping with those of our recent single unit work in dorsal horn convergent neurons.
journal_name
Brain Resjournal_title
Brain researchauthors
Kraus E,Besson JM,Le Bars Ddoi
10.1016/0006-8993(82)90384-5subject
Has Abstractpub_date
1982-01-14 00:00:00pages
461-5issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(82)90384-5journal_volume
231pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The retrograde transport of fluorescent substances was used in order to investigate divergent axon collaterals of neurons in the nucleus prepositus hypoglossi (Ph). Fast blue (FB) was injected into the flocculus, paraflocculus and/or the vermis, while nuclear yellow (NY) was injected into the oculomotor nucleus alone ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90150-0
更新日期:1982-08-19 00:00:00
abstract::In this study intracellular recording techniques were used to study the synaptic events related to phase-locking of cochlear nucleus cells to low frequency stimuli. A variable degree of phase-locking was noted even with units of the same low characteristic frequency. With low frequency phase-locking units an excitator...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90286-9
更新日期:1976-08-13 00:00:00
abstract::Previous studies have shown that one of the genetic variants BDNF val66met polymorphism is associated with drug addiction. Age at onset for drugs abuse has also been regularly cited as a factor associated with high genetic predispositions. We conducted an exploratory research to investigate the association of BDNF val...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.07.022
更新日期:2010-09-24 00:00:00
abstract::The sexually dimorphic nucleus of the preoptic area (SDN-POA) is the most striking structure displaying a morphological sex difference in the rat brain. A potentially homologous nucleus has been identified in the human hypothalamus. The objective of the present study was to pursue the putative homology of the rat and ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(96)01005-0
更新日期:1996-12-02 00:00:00
abstract::Efflux of choline from the rat cerebral cortex in vivo was investigated using the cup technique. After removal of the dura mater, the cup was placed on the cortex. Transmission and scanning electron microscopy revealed that the cortex was separated from the cup solution (100-300 microliter) by basal lamina, pia mater,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91007-8
更新日期:1985-10-21 00:00:00
abstract::Interactions between brain alpha2- and beta-adrenoceptors are of interest in physiological (aging) and pathological (major depression) processes involving both receptors. In this study, total beta-adrenoceptors and beta1/2-subtypes were quantitated in postmortem human brains to investigate their relationships with alp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02190-4
更新日期:2001-04-20 00:00:00
abstract::Proliferative response of astrocytes to unilateral injury of the cerebral hemisphere was investigated in 30-day-old rats using a combination of [3H]thymidine autoradiography and immunocytochemical staining for glial fibrillary acidic protein. At different intervals following injury the animals were injected with [3H]t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90566-0
更新日期:1989-04-24 00:00:00
abstract::Lithium is known to potentiate the ability of pilocarpine to induce status epilepticus in rats. The goal of this study was to determine whether lithium could potentiate pilocarpine-induced seizures in developing animals. Behavioral, electroencephalographic (EEG), and histopathological changes induced by systemic admin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(10)80015-0
更新日期:1992-06-26 00:00:00
abstract::We tested the hypothesis that intravenous infusion of human marrow stromal cells (hMSC) with a nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) aminio] diazen-1-ium-1,2-diolate (DETA/NONOate), enhances angiogenesis, neurogenesis and neurological functional recovery after stroke in rats compared to indivi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.11.080
更新日期:2004-04-16 00:00:00
abstract::Transfer learning is an immanent feature of perceptual learning. Yet, despite the increasingly widespread application of transcranial direct current stimulation (tDCS) to study learning, transfer effects in response to tDCS have not been studied. Therefore, the present study investigated the transfer of tactile acuity...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.03.031
更新日期:2018-06-15 00:00:00
abstract::In this report, using a push-pull perfusion technique, we examined in vivo the effects of exogenous dopamine (DA) on the output of neurochemical substances from the caudate nucleus (CN) of freely behaving rats. Exogenous DA, at concentrations of 10(-5) M, 5 x 10(-5) M and 10(-4) M, in modified Krebs-Ringer phosphate m...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90803-2
更新日期:1989-03-06 00:00:00
abstract::Eye and head movements during tracking of a smoothly moving visual target were recorded in trained monkeys. The head movement clearly followed the target, although with considerable variability from cycle to cycle. The eye stayed relatively near the primary position and moved in an apparently irregular fashion; howeve...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(78)91127-7
更新日期:1978-09-15 00:00:00
abstract::Circling training during rat striatum postnatal critical period (PN30 to 37 days) induces a life-lasting co-reduction of muscarinic acetylcholine receptors (mAChR) and dopamine D2 receptors (D2R) binding. Here, we evaluated the expression of D1R and D2R under similar experimental conditions. Trained rats showed a decr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.01.050
更新日期:2004-04-09 00:00:00
abstract::The effects of intracerebroventricular injections of 8-OH-DPAT (a 5-HT1A agonist; 3, 15 or 30 nmol) or GR46611 (a 5-HT1B/1D agonist; 3, 15 or 30 nmol) on feeding, drinking, preening and sleep-like behaviors were investigated in free-feeding (FF) pigeons. The effects of these 5-HT agonists on blood glucose and free fat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.08.031
更新日期:2004-11-12 00:00:00
abstract::We have found that daily subcutaneous injection with a maximum tolerated dose (MTD) of the mGluR2/3 agonist LY379268 (20mg/kg) beginning at 4 weeks dramatically improves the phenotype in R6/2 mice. For example, we observed normalization of motor function in distance traveled, speed, the infrequency of pauses, and the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2012.07.026
更新日期:2012-09-14 00:00:00
abstract::During retinal development, common precursors give rise to various types of cells in a time course specific to each cell type. Previously, we demonstrated that the bHLH gene Hes1 inhibits neuronal differentiation whereas, in Hes1-null retina, precursors prematurely differentiate into neurons and form abnormal rosette-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.01.045
更新日期:2004-04-09 00:00:00
abstract::Calcium currents were studied in morphologically identified pyramidal and stellate neurons acutely isolated from layer II/III of rat entorhinal cortex, using the whole-cell patch-clamp configuration. The peak amplitude of high-voltage activated current (HVA) measured at +10 mV was not different in both neuron populati...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)01234-7
更新日期:1999-01-23 00:00:00
abstract::Granule cell progenitors in the dentate gyrus of the hippocampal formation have the unusual capacity to be able to divide in the brains of adult rats and primates. The basal proliferation rate of granule cell progenitors in the adult rat is low compared with development, however, it is possible that this rate may beco...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00030-4
更新日期:1998-04-20 00:00:00
abstract::The possibility of retinotopic organization of pathways of retinal fibers within the optic tract and the tectum of the frog was studied by selective labeling of the retinal fibers with horseradish peroxidase. Within the optic tract the pathways of the ventral, temporal and dorsal retinal fibers were ordered from the d...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90097-4
更新日期:1981-02-09 00:00:00
abstract::An autoradiographic determination of the time of origin of the lateral motor columns (LMC) of the chick embryo has been made. The first motor neurons of the brachial LMC are born at stage 15; the earliest birthdates of lumbar LMC neurons are at stage 17. At least 95% of the motor neurons of both brachial and lumbar co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90416-4
更新日期:1977-08-26 00:00:00
abstract::The neurite promoting factors in the astroglial conditioned medium (As-CM) were characterized by using primary cultures of embryonic rat neocortical neurons. The factors in the As-CM bind to lectins such as wheat germ agglutinin (WGA), suggesting that they contain sugar moieties. When the WGA-bound fractions were appl...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91059-p
更新日期:1990-09-10 00:00:00
abstract::While it is generally assumed that cocaine self-administration (SA) is determined and maintained by the pharmacological actions of cocaine in the brain, it is also a drug-motivated and drug-reinforced goal-directed behavior, which is determined by concurrent learning and behavioral performance. To dissociate the contr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.01.038
更新日期:2004-04-16 00:00:00
abstract::We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.07.051
更新日期:2015-10-22 00:00:00
abstract::Recurrent exposure to intermittent electrical foot-shock (30 min, twice daily) for 7 days caused an increase in immunoreactive (ir) dynorphin and ir-alpha-neo-endorphin in lumbar and cervical (but not thoracic) spinal cord as measured 16 h following the final session. At this time the level of ir-Met-enkephalin-Arg6-G...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91012-2
更新日期:1987-06-16 00:00:00
abstract::Repeated cocaine exposure alters medial prefrontal cortex (mPFC) function to allow for enhanced excitatory transmission to the nucleus accumbens and ventral tegmental area (VTA). Previous studies have demonstrated changes in receptor function in the mPFC in animals repeatedly exposed to cocaine that produced increased...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.07.029
更新日期:2018-11-01 00:00:00
abstract::An immunohistochemical investigation of the bovine pineal gland was performed using both a rabbit polyclonal antibody and a rat monoclonal antibody against choline acetyltransferase (ChAT). A network of ChAT-immunoreactive (IR) nerve fibers was located throughout the pineal gland, both in the perivascular spaces and b...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91268-6
更新日期:1991-04-05 00:00:00
abstract::Fast axonal transport and neuronal protein synthesis was studied in the isolated nervous system of Aplysia californica. The abdominal ganglion with attached pleural-abdominal connectives (PAC) was removed and the ganglion pulse-labelled with [35S]methionine for 30 min in vitro. The axon containing connectives were lig...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90388-9
更新日期:1985-04-15 00:00:00
abstract::Dual-labeling immunohistochemical or in situ hybridization studies for the recently cloned epsilon-subunit and several neuropeptides were performed in the rat hypothalamus. We revealed an extensive co-expression (>90%) with hypocretin (Hcrt), oxytocin (OT), the gonadotropin-releasing hormone (GnRH), and the melanin-co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)04270-1
更新日期:2003-03-28 00:00:00
abstract::In the course of pulse-label studies on the axonal transport of the small, basic, actin-binding proteins--actin depolymerizing factor, cofilin and profilin--in chicken motor neurones, we observed a heavily labelled protein of M(r) 18 kDa and pI 8.2 on fluorographs of two-dimensional polyacrylamide gels. On the basis o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00766-x
更新日期:1997-10-17 00:00:00
abstract::To characterize optical responses (ORs) evoked by white matter (WM) stimulation in slices of rat visual cortex (VC) stained with voltage sensitive dyes, time course of ORs in each layer was investigated by recording ORs with a linearly aligned photodiode array, and the spatial patterns of the ORs at specified time aft...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00767-6
更新日期:1996-10-28 00:00:00