The projection from striate and extrastriate cortical areas to the superior colliculus in the rat.

abstract：:Recently, much attention has focused on the role of the melanocortin system in the regulation of energy homeostasis, especially the satiety effects of the pro-opiomelanocortin (POMC)-derived peptide alpha-melanocyte stimulating hormone (alpha-MSH). We have found that POMC mRNA levels are similar in fat and thin sheep ...

journal_title：Brain research

authors： Henry BA,Rao A,Ikenasio BA,Mountjoy KG,Tilbrook AJ,Clarke IJ

更新日期：2001-11-09 00:00:00

abstract：:Release of Ca(2+) from intracellular Ca(2+) stores (ICS) is involved in age-related changes in the induction of long-term potentiation. However, the role of this Ca(2+) source for the increased susceptibility to long-term depression (LTD) with advanced age is unknown. Extracellular excitatory postsynaptic field potent...

journal_title：Brain research

authors： Kumar A,Foster TC

更新日期：2005-01-07 00:00:00

abstract：:The senescence-accelerated mouse prone 8 (SAMP8) is a novel aging model characterized by early onset and rapid advancement of senescence. In the present study, 6-month-old male SAMP8 mice were orally administered icariin (75, 150mg/kg) for 15weeks. Mice were submitted to passageway water maze test and step-down passiv...

journal_title：Brain research

authors： He XL,Zhou WQ,Bi MG,Du GH

更新日期：2010-06-02 00:00:00

abstract：:The suspected functional role of dendritic spines as loci of neuronal plasticity (possibly memory and learning) is greatly enriched when active membrane properties are assumed at the spine head. Computations with reasonable electrical and structural parameter values (corresponding to an optimal range for spine stem re...

journal_title：Brain research

authors： Miller JP,Rall W,Rinzel J

更新日期：1985-01-28 00:00:00

abstract：:The compound m-chlorophenylpiperazine (m-CPP) is used clinically to manipulate serotonergic function, though its precise mechanisms of actions are not well understood. m-CPP alters synaptic transmission and neuronal function in vertebrates by non-selective agonistic actions on 5-HT(1) and 5-HT(2) receptors. In this st...

journal_title：Brain research

authors： Sparks GM,Brailoiu E,Brailoiu GC,Dun NJ,Tabor J,Cooper RL

更新日期：2003-04-18 00:00:00

abstract：:Previous reports of the distribution of calbindin, a 28 kDa vitamin D-induced calcium-binding protein, in the mammalian peripheral vestibular system postulated that this protein was involved in the calcium-dependent mechanisms occurring in the hair cells and ganglion cells. In this study, we examined the possibility o...

journal_title：Brain research

authors： Dechesne CJ,Thomasset M

更新日期：1988-05-16 00:00:00

abstract：:The effect of intracerebroventricular administration of dizocilpine on feeding behaviour and adrenal corticrotropic hormone (ACTH)-induced anorexia in elevated plus maze was examined. Dizocilpine (10, 20 and 40 nmol/rat, i.c.v.) showed a dose-dependent increase in food intake in 16 h food deprived rats. Dopamine recep...

journal_title：Brain research

authors： Ninan I,Kulkarni SK

更新日期：1998-11-23 00:00:00

abstract：:The effects of acetylcholine (ACh) and physostigmine (PHY) on thoracic ganglion neurons of Locusta migratoria were investigated using whole-cell and cell-attached voltage clamp. ACh activated whole-cell currents with variable amplitudes, time course and ion channel block between cells, suggesting differential expressi...

journal_title：Brain research

authors： van den Beukel I,van Kleef RG,Zwart R,Oortgiesen M

更新日期：1998-04-13 00:00:00

abstract：:Angiotensin converting enzyme (ACE) is Zn2+ metallopeptidase which plays an important role in blood pressure homeostasis in mammals and other vertebrates. Homologues of ACE involved in the biosynthesis of mammalian peptide hormones have also been identified in the insects, Musca domestica, Drosophila melanogaster and ...

journal_title：Brain research

authors： Schoofs L,Veelaert D,De Loof A,Huybrechts R,Isaac E

更新日期：1998-03-02 00:00:00

abstract：:The potential evoked at the surface of the cerebral cortex of a guinea pig, by stimulation of the contralateral forepaw, usually consists of an initial double positive wave whose waveform remains unchanged during rapid stimulation. In a guinea pig with experimental allergic encephalomyelitis (EAE) the response is atte...

journal_title：Brain research

authors： Lumsden CE,Howard L,Aparicio SR

更新日期：1975-08-08 00:00:00

abstract：:Sustained neuroinflammation contributes to the pathogenesis of postoperative cognitive dysfunction. Dexmedetomidine, a selective α-2 adrenergic receptor agonist, exhibits a protective role in the brain. This study investigated whether dexmedetomidine pretreatment attenuates neuroinflammation induced by tibial fracture...

journal_title：Brain research

authors： Zhu YJ,Peng K,Meng XW,Ji FH

更新日期：2016-08-01 00:00:00

abstract：:Cerebral amyloid angiopathy (CAA) might disturb the sensitive mechanism of cerebral pressure autoregulation. This study examines whether dynamic cerebral autoregulation (CA) is impaired in the posterior or anterior circulation of CAA patients. Fifteen patients with known CAA on magnetic resonance imaging (MRI) and 14 ...

journal_title：Brain research

authors： Reinhard M,Lorenz L,Sommerlade L,Allignol A,Urbach H,Weiller C,Egger K

更新日期：2019-08-15 00:00:00

abstract：:Research supports the effectiveness of acupuncture for conditions such as chronic low back and knee pain. In a five-patient pilot study the modality also improved the symptoms of chemotherapy-induced neuropathic pain. Using an established rat model of paclitaxel-induced peripheral neuropathy, we evaluated the effect o...

journal_title：Brain research

authors： Meng X,Zhang Y,Li A,Xin J,Lao L,Ren K,Berman BM,Tan M,Zhang RX

更新日期：2011-09-26 00:00:00

abstract：:The effects of alpha-bungarotoxin from Bungarus multicinctus and Bungarus caeruleus were studied on three types of cholinergic response in Aplysia central neurones. These responses are the result of three distinct changes in ionic permeability: selective increases in permeabiliyt to Na, Cl and K, respectively. It was ...

journal_title：Brain research

authors： Kehoe J,Sealock R,Bon C

更新日期：1976-05-14 00:00:00

abstract：:The phenomenon of unidirectional non-cross tolerance (UNCT) to etorphine was observed in adult male rats tolerant to morphine. Using a morphine pellet (four 75 mg morphine pellets) implantation protocol, a 10-fold increase in the analgesic ED50 value, obtained by tail-flick assay, was observed for morphine sulfate, wi...

journal_title：Brain research

authors： Roerig SC,Fujimoto JM,Franklin RB,Lange DG

更新日期：1985-02-18 00:00:00

abstract：:We examined the effect of nitric oxide (NO) on the expression of phosphorylated cAMP response element binding (pCREB) protein and on the polysialylated form of the neural cell adhesion molecule (PSA-NCAM), in the hippocampus of the adult rat, by administering 7-nitroindazole (7-NI) for 5 days, to block neuronal nitric...

journal_title：Brain research

authors： Park C,Cho K,Ryu JH,Shin KS,Kim J,Ahn H,Huh Y

更新日期：2004-05-15 00:00:00

abstract：:3,4-Dihydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A metabolite of norepinephrine and epinephrine. DOPEGAL, but not other metabolites, kills differentiated PC-12 cells. However, the type of DOPEGAL induced cell death, whether necrosis or apoptosis, is not known. To determine the type of cell death tr...

journal_title：Brain research

authors： Burke WJ,Schmitt CA,Miller C,Li SW

更新日期：1997-06-20 00:00:00

abstract：:We assessed the effects of simulated weightlessness, hindlimb unloading (HU) by 7 days of tail suspension, on noxious mechanically and heat evoked spinal withdrawal reflexes and spinal Fos expression during muscle nociception elicited by intramuscular (i.m.) injection of hypertonic (HT; 5.8%) saline into gastrocnemius...

journal_title：Brain research

authors： Lei J,Pertovaara A,You HJ

更新日期：2015-01-12 00:00:00

abstract：:Transforming growth factor beta (TGFbeta) modulates a variety of growth related functions following traumatic injury. The cellular response to TGFbeta is predominantly mediated through TGFbeta receptor I (TGFbetaRI) and receptor II (TGFbetaRII) on the cell surface and SMAD proteins intracellularly. We investigated the...

journal_title：Brain research

authors： Fee DB,Sewell DL,Andresen K,Jacques TJ,Piaskowski S,Barger BA,Hart MN,Fabry Z

更新日期：2004-06-25 00:00:00

abstract：:We previously reported that the level of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) alpha and beta proteins increases with postnatal age. In the present study, we investigated the developmental changes in whole protein substrates of CaM kinase II as compared with those of cAMP-dependent protein kinase...

journal_title：Brain research

authors： Sugiura H,Yamauchi T

更新日期：1994-10-03 00:00:00

abstract：:Glycans are components of glycoconjugates and function in odorant recognition and cell signaling in the olfactory mucosa. However, little is known about glycan expression in the olfactory mucosa in the presence of neuroinflammatory disorders, which can influence olfaction. We evaluated the changes in glycan in the olf...

journal_title：Brain research

authors： Park C,Kim J,Ahn M,Choi Y,Shin T

更新日期：2020-04-01 00:00:00

abstract：:A small, unilateral, penetrating wound was placed in the dorsolateral portion of the lumbosacral spinal cord in immature rats. Although this wound did not extend into the central canal area, some cells forming the walls of this canal underwent proliferative activity as demonstrated by [3H]thymidine autoradiography. Th...

journal_title：Brain research

authors： Gilmore SA,Leiting JE

更新日期：1980-11-10 00:00:00

abstract：:The effects of the possible metabolites of taurine--taurocyamine and hypotaurine--and of homotaurine on spike discharge frequency of guinea pig cerebellar Purkinje cells were investigated in comparison with taurine and GABA. Taurocyamine, hypotaurine and homotaurine all dose-dependently suppressed the spike frequency ...

journal_title：Brain research

authors： Okamoto K,Sakai Y

更新日期：1981-02-16 00:00:00

abstract：:The aim of this study was to determine the effect of different concentrations of normobaric oxygen (NBO) on neurological function and the expression of caspase-3 and -9 in a rat model of acute cerebral ischaemia. Sprague-Dawley rats (n=120) were randomly divided into four groups (n=30 per group), including 3 groups gi...

journal_title：Brain research

authors： Chen S,Peng H,Rowat A,Gao F,Zhang Z,Wang P,Zhang W,Wang X,Qu L

更新日期：2015-08-27 00:00:00

abstract：:Stroke is the third leading cause of death in the US, with a prevalence of 750,000 patients per year, and a social cost estimated at $50 billion. Current therapeutics are targeted at restoring blood flow rather than on preventing the actual mechanisms associated with neuronal cell death. Here, we show that, following ...

journal_title：Brain research

authors： Yoshimoto T,Kanakaraj P,Ying Ma J,Cheng M,Kerr I,Malaiyandi L,Watson JA,Siesjö BK,Maples KR

更新日期：2002-08-30 00:00:00

abstract：:Brain capillaries form a selective interface, the blood-brain barrier (BBB), between the neural parenchyma and the blood. The factors which regulate this interface are poorly understood. Both the iris and retina possess vascular beds that express some BBB characteristics; therefore, they provide attractive models to f...

journal_title：Brain research

authors： Holash JA,Stewart PA

更新日期：1993-12-03 00:00:00

abstract：:The effects of undernutrition during pregnancy and/or lactation periods on cortical structures have already been reported. However, its effect on non-cortical areas like the hypothalamic, that participates in the regulation of the autonomic nervous system or food intake, has not been extensively investigated. We studi...

journal_title：Brain research

authors： González-Pardo H,Gutiérrez-Sánchez JM,Menéndez-Patterson A,Arias JL

更新日期：1994-08-15 00:00:00

abstract：:Intracisternal (i.c.) administration of the glutamate-receptor antagonist kynurenate to halothane-anesthetized rats (paralyzed, ventilated) produced an initial hypertension associated with an increase in lumbar sympathetic nerve discharge. Kynurenate (i.c.) blocked or greatly reduced all sympathetic reflexes investiga...

journal_title：Brain research

authors： Sun MK,Hackett JT,Guyenet PG

更新日期：1988-01-12 00:00:00

abstract：:Extracellular action potentials were recorded from 691 neurons in the ventromedial hypothalamus (VMH) of urethane anesthetized female rats under acute and chronic sham-operated and hyperprolactinemic conditions. Hyperprolactinemia was produced by transplanting pituitaries under the kidney capsules. Neuronal excitabili...

journal_title：Brain research

authors： Moss RL,Chan A,Dudley CA

更新日期：1985-11-04 00:00:00

abstract：:Extracellular recordings were carried out in the primary visual cortex of behaving monkeys. Neurons were activated by moving a visual stimulus on their receptive fields during periods of steady fixation and by moving their receptive fields (smooth pursuit eye movements) on a motionless visual stimulus. Regarding non-o...

journal_title：Brain research

authors： Galletti C,Squatrito S,Battaglini PP,Maioli MG

更新日期：1983-01-31 00:00:00