7-Nitroindazole upregulates phosphorylated cAMP response element binding protein, polysialylated-neural cell adhesion molecule and tryptophan hydroxylase expression in the adult rat hippocampus.

abstract：:When female golden hamsters are maintained on a photoperiod of less than 12.5 h of light per day, they go into a pineal gland-induced anestrus in 6-10 weeks. This acyclicity is similar in certain respects to the testicular regression which occurs in male golden hamsters maintained on a short photoperiod. A recent stud...

journal_title：Brain research

authors： Pieper DR,Samyn MM,Heverly RN

更新日期：1986-08-13 00:00:00

abstract：:The trace elemental concentrations, including iron, in the substantia nigra (SN) of a 6-OHDA induced rat model of Parkinson's disease were measured using nuclear microscopy. Only rats that exhibited amphetamine induced rotation of more than 7 turns/min were used. The results showed that the iron levels were significan...

journal_title：Brain research

authors： He Y,Thong PS,Lee T,Leong SK,Shi CY,Wong PT,Yuan SY,Watt F

更新日期：1996-09-30 00:00:00

abstract：:Injury of peripheral nerves often results in hyperalgesia (an increased sensitivity to painful stimuli). This hyperalgesia is mediated in part by sympathetic neurotransmitters. We examined the effect of neuropeptide Y (NPY), specific Y1 and Y2 agonists, and an NPY antagonist on peripheral hyperalgesia in rats whose sc...

journal_title：Brain research

authors： Tracey DJ,Romm MA,Yao NN

更新日期：1995-01-16 00:00:00

abstract：:The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...

journal_title：Brain research

authors： Watanabe Y,Watanabe T,Kitagawa M,Taya Y,Nakayama K,Motoyama N

更新日期：1999-09-25 00:00:00

abstract：:Endothelins are potent vasoconstrictors and signaling molecules. Their effects are broad, impacting processes ranging from neurovascular and cardiovascular health to cell migration and survival. In stroke, traumatic brain injury or subarachnoid hemorrhage, endothelin-1 (ET-1) is induced resulting in cerebral vasospasm...

journal_title：Brain research

authors： Bickford JS,Ali NF,Nick JA,Al-Yahia M,Beachy DE,Doré S,Nick HS,Waters MF

更新日期：2014-11-07 00:00:00

abstract：:Bombesin-like immunoreactivity occurs in a dense network of nerve fibres in the rat coeliac-superior mesenteric ganglion. No bombesin immunoreactive cell bodies have been observed in this ganglion. An origin outside the ganglion was therefore assumed for the bombesin immunoreactive fibres. Ligation of the mesenteric n...

journal_title：Brain research

authors： Schultzberg M,Dalsgaard CJ

更新日期：1983-06-13 00:00:00

abstract：:The carotid body of the mouse is ideally suited for in vitro photometric and fluorometric studies using transillumination. It is small, thin and translucent. Photometric recordings were made by using a dual wavelength method. Wavelengths of 550 nm (maximal absorbance, MA) and 540 nm (isosbestic point, IP) were employe...

journal_title：Brain research

authors： Acker H,Eyzaguirre C,Goldman WF

更新日期：1985-03-18 00:00:00

abstract：:Previous evidence suggests that preterm newborns with intrauterine growth restriction (IUGR) have specific neurostructural and neurodevelopmental anomalies, but it is unknown whether these effects persist in early childhood. We studied a sample of 18 preterm IUGR, 15 preterm AGA - born between 26 and 34 weeks of gesta...

journal_title：Brain research

authors： Padilla N,Falcón C,Sanz-Cortés M,Figueras F,Bargallo N,Crispi F,Eixarch E,Arranz A,Botet F,Gratacós E

更新日期：2011-03-25 00:00:00

abstract：:Extracellular signal-regulated kinase 1/2 (ERK1/2) plays diverse roles in the central nervous system. Activation of ERK1/2 has been observed in various types of neuronal excitation, including seizure activity in vivo and in vitro. However, studies examining ERK1/2 activity and its substrate phosphorylation in parallel...

journal_title：Brain research

authors： Yamagata Y,Nairn AC

更新日期：2015-11-02 00:00:00

abstract：:This study attempted to ascertain whether heatstroke-induced ischemia is associated with augmented striatal glutamate release and can be attenuated by NMDA receptor antagonists. Mean arterial pressure (MAP), striatal cerebral blood flow (CBF), striatal glutamate release and striatal neuronal damage score were assessed...

journal_title：Brain research

authors： Yang YL,Pan WH,Chiu TH,Lin MT

更新日期：1998-06-08 00:00:00

abstract：:Inflammation and immune response have been implicated in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH). Recently, increased TLR4 expression has been associated with the development of cerebral vasospasm in a rabbit model of SAH. Peroxisome proliferator-activated receptor gamma (PPARgamma) ...

journal_title：Brain research

authors： Wu Y,Zhao XD,Zhuang Z,Xue YJ,Cheng HL,Yin HX,Shi JX

更新日期：2010-03-31 00:00:00

abstract：:Patients with sickle cell disease (SCD) can develop strokes and as a result, present neurologic and neurocognitive deficits. However, recent studies show that even without detectable cerebral parenchymal abnormalities on imaging studies, SCD patients can have significant cognitive and motor dysfunction, which can pres...

journal_title：Brain research

authors： Almeida LEF,Wang L,Kamimura S,Zerfas PM,Smith ML,Neto OLA,Vale T,Quezado MM,Horkayne-Szakaly I,Wakim P,Quezado ZMN

更新日期：2020-11-01 00:00:00

abstract：:When observing bistable stimuli, the percept can change in the absence of changes in the stimulus itself. When intermittently presenting a bistable stimulus, the number of perceptual alternations can increase or decrease, depending on the duration of the period that the stimulus is removed from screen between stimulus...

journal_title：Brain research

authors： Raemaekers M,van der Schaaf ME,van Ee R,van Wezel RJ

更新日期：2009-02-03 00:00:00

abstract：:Individual vulnerability to the reinforcing effects of drugs appear to be a crucial factor in the development of addiction in humans. In the rat, individuals at risk for psychostimulant self-administration (SA) may be identified from their locomotor reactivity to a stress situation such as exposure to a novel environm...

journal_title：Brain research

authors： Piazza PV,Rougé-Pont F,Deminière JM,Kharoubi M,Le Moal M,Simon H

更新日期：1991-12-13 00:00:00

abstract：:Ouabain binds to the catalytic subunit of Na+,K+-ATPase and specific [3H]ouabain binding can be used as a measure of the number of active enzyme molecules present in a given tissue. Specific [3H]ouabain binding can be demonstrated in frozen, cryostat sections from rat brain and pineal and these sites have the characte...

journal_title：Brain research

authors： Caspers ML,Schwartz RD,Labarca R,Paul SM

更新日期：1987-04-21 00:00:00

abstract：:We have recently reported spinal blood flow-metabolism uncoupling in an amyotrophic lateral sclerosis (ALS) animal model using Cu/Zn-superoxide dismutase 1 (SOD1)-transgenic (Tg) mice, suggesting a relative hypoxia in the spinal cord. However, the hypoxic stress sensor pathway has not been well studied in ALS. Here, w...

journal_title：Brain research

authors： Sato K,Morimoto N,Kurata T,Mimoto T,Miyazaki K,Ikeda Y,Abe K

更新日期：2012-09-14 00:00:00

abstract：:This study determined if vasopressin generates superoxide anion (O2(-)) in a cyclooxygenase dependent manner and if such production contributes to impairment of dilation to activators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid percussion brain injury (FPI) in newborn pig...

journal_title：Brain research

authors： Armstead WM

更新日期：2001-08-10 00:00:00

abstract：:The known neurochemical effect of most currently available antidepressants is the enhancement of the synaptic levels of monoamine neurotransmitters. However, the existence of other mechanisms has been suggested to justify the significant delay between the modulation of the monoaminergic system and the clinical effects...

journal_title：Brain research

authors： Cecconi D,Mion S,Astner H,Domenici E,Righetti PG,Carboni L

更新日期：2007-03-02 00:00:00

abstract：:Previous work had indicated that animals that were sleep-deprived and then trained on a passive avoidance task show poor retention of the task 24 h later after being allowed to sleep freely again. Cholinergic involvement is suggested by the fact that this effect is prevented by treatment with the muscarinic agonist pi...

journal_title：Brain research

authors： Moreira KM,Hipólide DC,Nobrega JN,Bueno OF,Tufik S,Oliveira MG

更新日期：2003-07-04 00:00:00

abstract：:The effects of escapable and yoked inescapable electric tailshocks on extracellular levels of serotonin (5-HT) in the basolateral amygdala were measured by in vivo microdialysis. Inescapable, but not escapable, shock increased extracellular 5-HT in the amygdala relative to restrained controls. Basal levels of 5-HT wer...

journal_title：Brain research

authors： Amat J,Matus-Amat P,Watkins LR,Maier SF

更新日期：1998-11-23 00:00:00

abstract：:The effects of repetitive pilocarpine-induced status epilepticus (SE) in the hippocampal Na(+)/K(+)ATPase activity were studied in developing rat. Na(+)/K(+)ATPase is a membrane-bound enzyme responsible for the active transport of sodium and potassium ions through the membrane. It is necessary to maintain neuronal exc...

journal_title：Brain research

authors： Reime Kinjo E,Arida RM,Mara de Oliveira D,da Silva Fernandes MJ

更新日期：2007-03-23 00:00:00

abstract：:Our recent researches have identified increased expression of miR-21-5p in rats brain following traumatic brain injury (TBI), which protected against blood-brain barrier (BBB) damage. To further study the mechanism underlying the role of miR-21-5p on alleviating BBB damage after TBI, we performed the scratch injury mo...

journal_title：Brain research

authors： Ge X,Huang S,Gao H,Han Z,Chen F,Zhang S,Wang Z,Kang C,Jiang R,Yue S,Lei P,Zhang J

更新日期：2016-11-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that ATP elevates cytosolic free Ca2+ levels ([Ca2+]i) in myenteric neurons expressing the Ca2+ binding protein, calbindin-D28. A laser microbeam marked the location of cultured neurons on coverslips and provided unequivocal relocation of ATP-responsive neurons after im...

journal_title：Brain research

authors： Christofi FL,Guan Z,Lucas JH,Rosenberg-Schaffer LJ,Stokes BT

更新日期：1996-07-01 00:00:00

abstract：:The present study attempts to elucidate the possible role of adenosine 3',5'-monophosphate (cAMP) and prostaglandin E2 (PGE2) in the function of the neural luteinizing hormone-releasing hormone (LH-RH) apparatus. To this end, in vitro LH-RH release from superfused hypothalamic fragments and cAMP production by hypothal...

journal_title：Brain research

authors： Kim K,Ramirez VD

更新日期：1986-10-29 00:00:00

abstract：:Acetylcholinesterase (AChE) histochemical staining occurred in neurons of the dentate gyrus at the day of birth and steadily increased in intensity and distribution during the first 3 postnatal weeks until the adult pattern was reached. Granule cells failed to display AChE staining; however, the somata of most non-pri...

journal_title：Brain research

authors： Seress L,Robertson RT,Ribak CE

更新日期：1987-11-01 00:00:00

abstract：:MabQ155, a monoclonal antibody against synaptophysin, has been used to conduct a light microscopic survey of synaptogenesis in the suprachiasmatic nucleus of the perinatal rat. Synaptophysin is an integral component of synaptic vesicle membranes which is expressed in growth cones and growth cone filopodia as well as i...

journal_title：Brain research

authors： Laemle LK,Repke KB,Hawkes R,Rice FL

更新日期：1991-03-22 00:00:00

abstract：:For the purpose of obtaining chemical information about the physiological role of N-acetylaspartylglutamate (NAAG), the release of endogenous NAAG from and the uptake of [3H]NAAG by Guinea pig cerebellar slices were investigated in comparison with L-aspartate (Asp) and L-glutamate (Glu). Although endogenous NAAG was f...

journal_title：Brain research

authors： Sekiguchi M,Okamoto K,Sakai Y

更新日期：1989-03-13 00:00:00

abstract：:6-[18F]Fluoro-L-DOPA (FDOPA) is an imaging agent used in the study of dopamine terminals in the living brain using positron emission tomography (PET). To better understand the role of tracer metabolism in dynamic FDOPA PET studies, the pharmacokinetics of individual FDOPA metabolites in extracellular space in the stri...

journal_title：Brain research

authors： DeJesus OT,Haaparanta M,Solin O,Nickles RJ

更新日期：2000-09-15 00:00:00

abstract：:Alteration in the blood-nerve barrier may be of primary importance in the development of experimental lead neuropathy. Using quantitative track autoradiography, we have directly demonstrated that there is a 15-fold increase in the rate of 210Pb accumulation in the endoneurium 70 days after the onset of chronic intoxic...

journal_title：Brain research

authors： Windebank AJ,Dyck PJ

更新日期：1981-11-23 00:00:00

abstract：:The effect of intracerebroventricular (i.c.v.) infusion of various iso- and hypertonic saccharide solutions on water intake stimulated by intracarotid (i.c.) infusion of hypertonic NaCl was studied in sheep. Without an i.c.v. infusion, water intake during a 10-min period following an i.c. infusion of 4 M NaCl (1.4 ml/...

journal_title：Brain research

authors： Park R,Denton DA,McKinley MJ,Pennington G,Weisinger RS

更新日期：1989-07-24 00:00:00