Responsiveness to ATP with an increase in intracellular free Ca2+ is not a distinctive feature of calbindin-D28 immunoreactive neurons in myenteric ganglia.

abstract：:Traumatic brain injury (TBI) contributes to morbidity in children, and more boys experience TBI. Cerebral autoregulation is impaired after TBI, contributing to poor outcome. Cerebral Perfusion Pressure (CPP) is often normalized by use of vasoactive agents to increase mean arterial pressure (MAP). In prior studies of n...

journal_title：Brain research

authors： Curvello V,Hekierski H,Pastor P,Vavilala MS,Armstead WM

更新日期：2017-09-01 00:00:00

abstract：:Effects of inhibition of nitric oxide (NO) synthesis on the cerebrovascular autoregulatory vasodilator response to hypotension were studied in conscious rats. Cerebral blood flow (CBF) was determined with [14C]iodoantipyrine in a saline-treated control group and in three groups following inhibition of NO synthase acti...

journal_title：Brain research

authors： Takahashi S,Cook M,Jehle J,Kennedy C,Sokoloff L

更新日期：1995-04-24 00:00:00

abstract：:Experimental studies and clinical observations show that spinal cord lesions are greatly enlarged by a process called secondary cell death. A detailed understanding of the molecular and cellular processes underlying these events is still lacking. In clinical studies using methylprednisolone in spinal cord injured pati...

journal_title：Brain research

authors： Bartholdi D,Schwab ME

更新日期：1995-02-20 00:00:00

abstract：:The temporal and spatial distribution of immunocytochemically identified reactive astrocytes is described following a cerebral stab wound in adult rats. Different patterns of reactivity were observed in the cerebral cortex, the corpus callosum and the deep structures of the hemisphere. In the cerebral cortex, the zone...

journal_title：Brain research

authors： Mathewson AJ,Berry M

更新日期：1985-02-18 00:00:00

abstract：:The formation of reactive oxygen species (ROS) has been suggested to be associated with excitotoxicity but the involvement of cytoplasmic enzymes in ROS formation is not clearly known. In the present study, we examined the role of xanthine oxidase (XO), nitric oxide synthase (NOS) and phospholipase A(2) (PLA(2)) in gl...

journal_title：Brain research

authors： Sanganahalli BG,Joshi PG,Joshi NB

更新日期：2005-03-10 00:00:00

abstract：:The purpose of this study was to examine whether endothelium-mediated dilation is responsible for the cortical hyperemia that occurs during cortical spreading depression (CSD) in rats using three different approaches. The first approach taken was the acute pharmacological inhibition of the predominant endothelium-cent...

journal_title：Brain research

authors： Shimizu K,Miller AW,Erdös B,Bari F,Busija DW

更新日期：2002-02-22 00:00:00

abstract：:We have sought to determine if changes in arterial and gastric pressure occurred with selective chemical stimulation of the dorsomedial NTS. Substance P (SP) and L-glutamate (L-glu), but not acetylcholine (ACh), elicited a dose-dependent decrease in tonic gastric pressure and inhibited gastric phasic activity. As prev...

journal_title：Brain research

authors： Spencer SE,Talman WT

更新日期：1986-10-22 00:00:00

abstract：:Rat pinealocytes use L-glutamate as a modulator for melatonin synthesis. Upon binding of L-glutamate to the class II metabotropic glutamate receptor, norepinephrine (NE)-dependent formation of cAMP was inhibited, resulting in decreased serotonin-N-acetyltransferase (NAT) activity and melatonin output. Although L-gluta...

journal_title：Brain research

authors： Ishio S,Yamada H,Craft CM,Moriyama Y

更新日期：1999-12-11 00:00:00

abstract：:We have developed a serum-free chemically defined medium which allows the obtainment of a primary culture highly enriched in ciliated ependymal cells. Serum was never used. Mechanically dissociated neonatal rat brain hemisphere cells were seeded on a fibronectin substratum. Culture medium was minimum Eagle's medium un...

journal_title：Brain research

authors： Weibel M,Pettmann B,Artault JC,Sensenbrenner M,Labourdette G

更新日期：1986-03-01 00:00:00

abstract：:The role of nicotinic cholinergic transmission in cold stress-induced alterations in rat adrenomedullary tyrosine hydroxylase (TH) mRNA was investigated by RNA dot-blot hybridization, using a cloned TH cDNA probe. Chlorisondamine, a ganglionic blocking agent, greatly attenuated the induction of TH mRNA levels caused b...

journal_title：Brain research

authors： Stachowiak M,Stricker EM,Zigmond MJ,Kaplan BB

更新日期：1988-04-01 00:00:00

abstract：:Ouabain binds to the catalytic subunit of Na+,K+-ATPase and specific [3H]ouabain binding can be used as a measure of the number of active enzyme molecules present in a given tissue. Specific [3H]ouabain binding can be demonstrated in frozen, cryostat sections from rat brain and pineal and these sites have the characte...

journal_title：Brain research

authors： Caspers ML,Schwartz RD,Labarca R,Paul SM

更新日期：1987-04-21 00:00:00

abstract：:The blood-brain interface in elasmobranchs was examined using physiological and anatomical techniques. Electrolyte analyses of plasma and cerebrospinal fluid (CSF) in control fish and in fish with elevated plasma cation concentration (Ca, Mg or K) demonstrated homeostasis of CSF calcium and magnesium concentrations in...

journal_title：Brain research

authors： Bundgaard M,Cserr H

更新日期：1981-12-07 00:00:00

abstract：:The mesolimbic dopamine (DA) system has long been known to be involved in reward behaviors. As with other substances of abuse, it has been extensively reported that ethanol influences the dopaminergic system. The present study examined whether selectively bred Sardinian-alcohol-preferring (sP) and Sardinian alcohol no...

journal_title：Brain research

authors： Casu MA,Colombo G,Gessa GL,Pani L

更新日期：2002-01-11 00:00:00

abstract：:The ontogeny of muscarinic cholinergic receptors was studied in primary cultures of dissociated rat hippocampal cells. The specific [3H]quinuclidinyl benzilate [( 3H]QNB) to intact cells was detected after two days in culture. Scatchard analysis revealed only a unique binding site at all of the days tested, with a ver...

journal_title：Brain research

authors： Fernandez-Tomé P,Segal M

更新日期：1987-09-01 00:00:00

abstract：:This study examined the effects of stria terminalis (ST) lesions on glucocorticoid-induced modulation of memory formation for inhibitory avoidance training and spatial learning in a water maze. Systemic (s.c.) posttraining injections of the glucocorticoid receptor agonist dexamethasone (0.3 or 1.0 mg/kg) enhanced memo...

journal_title：Brain research

authors： Roozendaal B,McGaugh JL

更新日期：1996-02-19 00:00:00

abstract：:The effects of a conditioning lesion on the rate of sudomotor axon regeneration were judged by the recovery of sweat gland (SG) secretion after cholinergic stimulation. Three groups of mice were given a conditioning lesion by crushing the sciatic nerve at mid-thigh 4, 7, and 14 days before a test lesion. A 4th group r...

journal_title：Brain research

authors： Navarro X,Kennedy WR

更新日期：1990-02-19 00:00:00

abstract：:At various times after spinal nerve injury, dorsal root ganglia (DRGs) from injured segments were removed with attached dorsal roots and spinal nerves. In an in vitro recording chamber, spontaneously active units were recorded from teased dorsal root fascicles. Sustained spontaneous activity could first be recorded at...

journal_title：Brain research

authors： Liu X,Chung K,Chung JM

更新日期：1999-12-04 00:00:00

abstract：:Most experimental spinal cord injury studies described to date have relied on a limited number of injury gradations, and have tacitly assumed that outcome (functional, histological, and/or neurophysiological) is a monotonically graded function of injury severity. In contrast, the present study provides evidence that f...

journal_title：Brain research

authors： Gruner JA,Yee AK,Blight AR

更新日期：1996-08-05 00:00:00

abstract：:Chronically demyelinated lesions of cat dorsal columns were created by focal injection of the glial toxin ethidium bromide. Freeze-fracture studies show that the center of the lesion, which is devoid of glial cells and processes, contains axons having neither node-like nor paranodal-type membrane specializations. Near...

journal_title：Brain research

authors： Rosenbluth J,Tao-Cheng JH,Blakemore WF

更新日期：1985-12-09 00:00:00

abstract：:The recent indications of specialized lateralization of cardiovascular regulation within the right and left posterior insular cortex of the rat, suggest the possibility of transcallosal connectivity between these regions. This has not been previously demonstrated using physiological techniques. Extracellular neural re...

journal_title：Brain research

authors： Zhang Z,Oppenheimer SM

更新日期：2000-04-28 00:00:00

abstract：:There is a sizeable literature concerning basal ganglia (BG) functioning that is based on data from experiments employing a method of analysis that is traditionally used with other motor areas. A brief review of this literature is presented and the following conclusion is reached: as compared to the success of traditi...

journal_title：Brain research

authors： Lidsky TI,Manetto C,Schneider JS

更新日期：1985-06-01 00:00:00

abstract：:Neurons containing immunoreactivity to the endogenous lactose-binding lectin, RL-29, were examined in the L4 segment of the spinal cord of rats with an experimental neuropathy. The cells appeared by 5 days and were also present at 14 and 28 days postoperatively. All neurons were found in the dorsal horn ipsilateral to...

journal_title：Brain research

authors： Cameron AA,Dougherty PM,Garrison CJ,Willis WD,Carlton SM

更新日期：1993-08-20 00:00:00

abstract：:Effects of taurine on endogenous aspartic acid (Asp), glutamic acid (Glu) and gamma-aminobutyric acid (GABA) release has been investigated using synaptosomes prepared from rat cerebral cortex. Although basal release of these amino acids was not affected, taurine inhibited KCl (30 mM)-evoked overflow of Asp, Glu and GA...

journal_title：Brain research

authors： Kamisaki Y,Maeda K,Ishimura M,Omura H,Itoh T

更新日期：1993-11-12 00:00:00

abstract：:Ultrastructural localization of a calcium-binding protein, calretinin, in the cerebellar cortex of the rat was examined with an immunoperoxidase method. The cerebellar lobule V was investigated in detail. In the molecular layer, calretinin immunoreactivity was found in parallel fibers and in their varicosities that fo...

journal_title：Brain research

authors： Arai R,Jacobowitz DM,Deura S

更新日期：1993-06-11 00:00:00

abstract：:Intraperitoneal (i.p.) administration of sulfated CCK octapeptide (CCK-8S) has been shown to induce changes in neuronal activity in the nucleus of the solitary tract (NTS) and area postrema (AP), sensory parts of the dorsal vagal complex (DVC), and in the paraventricular nucleus of the hypothalamus (PVN), as determine...

journal_title：Brain research

authors： Mönnikes H,Lauer G,Arnold R

更新日期：1997-10-03 00:00:00

abstract：:Systemic administration of kainic acid in the rat results in the development of a characteristic excitotoxic syndrome, consisting of automatisms (wet dog shakes, WDS), sustained limbic seizures and brain damage. Since kainate increases the release of excitatory amino acid neurotransmitters such as glutamate, this synd...

journal_title：Brain research

authors： Baran H,Löscher W,Mevissen M

更新日期：1994-08-01 00:00:00

abstract：:We have characterized the effects of retinoic acid (RA) on the growth, morphology and biosynthesis of cytoskeletal proteins in NB2a mouse neuroblastoma cells. In addition, the morphological and biochemical changes were compared to those induced by dibutyryl cyclic AMP (db cAMP). Growth inhibition by RA was concentrati...

journal_title：Brain research

authors： Shea TB,Fischer I,Sapirstein VS

更新日期：1985-08-01 00:00:00

abstract：:Methylenedioxymethamphetamine (MDMA, Ecstasy) is a powerful releaser of serotonin. Increasing recreational use of this stimulant and hallucinogenic drug has raised concerns about its potential to produce brain damage. The vast majority of previous research studies have focused on the compound's ability to deplete sero...

journal_title：Brain research

authors： Schmued LC

更新日期：2003-06-06 00:00:00

abstract：:This study evaluated the effect of stress during puberty on sexual motivation and the correlation between serum testosterone levels (T) and the absolute power of the theta electroencephalographic rhythms, recorded in the medial prefrontal cortex (mPFC) and basolateral amygdala (BLA) of adult male rats. Thirty males of...

journal_title：Brain research

authors： Hernández-Arteaga E,Hernández-González M,Bonilla-Jaime H,Guevara MA,Ågmo A

更新日期：2020-10-15 00:00:00

abstract：:Hyperprolinemia type II is an autosomal recessive disorder caused by the severe deficiency of delta(1)-pyrroline-5-carboxylate dehydrogenase activity leading to tissue accumulation of proline (Pro). Most patients detected so far show neurological manifestations including epilepsy and mental retardation, whose pathophy...

journal_title：Brain research

authors： Delwing D,Bavaresco CS,Chiarani F,Wannmacher CM,Wajner M,Dutra-Filho CS,de Souza Wyse AT

更新日期：2003-11-21 00:00:00