Abstract:
:The role of nicotinic cholinergic transmission in cold stress-induced alterations in rat adrenomedullary tyrosine hydroxylase (TH) mRNA was investigated by RNA dot-blot hybridization, using a cloned TH cDNA probe. Chlorisondamine, a ganglionic blocking agent, greatly attenuated the induction of TH mRNA levels caused by cold exposure, whereas carbachol and nicotine, cholinergic agonists, increased TH mRNA in control animals. These results suggest that cholinergic nicotinic receptors play a key role in the transsynaptic induction of adrenal TH gene expression.
journal_name
Brain Resjournal_title
Brain researchauthors
Stachowiak M,Stricker EM,Zigmond MJ,Kaplan BBdoi
10.1016/0169-328x(88)90066-6subject
Has Abstractpub_date
1988-04-01 00:00:00pages
193-5issue
2eissn
0006-8993issn
1872-6240journal_volume
427pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The immunolocalization of the 14-3-3 eta isoform in the anterior horn cells (AHCs) of patients with sporadic amyotrophic lateral sclerosis (ALS) and controls was examined. Compared with the immunolocalization of other 14-3-3 isoforms, the immunolocalization of the 14-3-3 eta isoform was either synaptic at the peripher...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.05.051
更新日期:2016-09-01 00:00:00
abstract::The influence of extracellular sinusoidal electric fields on the amplitude of population spikes evoked by single test pulses in excitatory pathways to CA1 pyramidal neurons was studied in rat hippocampal slices. The fields in the tissue were of the order of EEG gradients. Stimulation at 5 Hz, a frequency representativ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90293-2
更新日期:1984-12-10 00:00:00
abstract::The aim of the present study was to investigate the anxiolytic effects of long-term treatment with fluoxetine in rats. Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, are used to treat anxiety and panic disorders, in addition to treating depression. A major concern with SSRIs is a 2-3-week delay i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)02289-1
更新日期:2000-02-07 00:00:00
abstract::Our previous studies indicated that L-type calcium channel blocker diltiazem could potentiate pentobarbital-induced hypnosis through serotonergic system. In view of the important role of dorsal raphe nucleus (DRN) on the sleep regulation and the pharmacological actions of calcium channel blocker, we presumed that Ca(2...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.05.064
更新日期:2011-07-27 00:00:00
abstract::Placental Opioid-Enhancing Factor (POEF) is a substance found in amniotic fluid (AF) that, when ingested, potentiates opioid-mediated, but not non-opioid-mediated, hypoalgesia. Vaginal-cervical stimulation (VCS) produces a stimulus-bound, partially opioid-mediated hypoalgesia that previous research has shown to be pot...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.12.055
更新日期:2011-02-28 00:00:00
abstract::Binding sites of atrial natriuretic peptide in the cerebral microvessels and choroid plexus of spontaneously hypertensive rats (SHR) and Wistar Kyoto control rats (WKY) were measured. In the microvessels, the number of ANP binding sites was lower in SHR than WKY, but there was no difference in affinity of binding site...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90984-j
更新日期:1990-06-04 00:00:00
abstract::A push-pull perfusion technique was employed for in vivo study of adenosine 3',5'-monophosphate (cAMP) and guanosine 3',5'-monophosphate (cGMP) in the rat caudate nucleus. Addition of dopamine to the perfusion fluid elicited dose-dependent increases of both cAMP and cGMP perfusate concentrations. In separate experimen...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90495-5
更新日期:1979-12-21 00:00:00
abstract::Oxidative stress and massive production of nitric oxide (NO) have been implicated in the neuropathogenesis following peripheral nerve injury. This study was aimed to ascertain whether melatonin would exert its neuroprotective effect on the lesioned hypoglossal neurons after peripheral axotomy, since it is known to red...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02489-6
更新日期:2000-08-11 00:00:00
abstract::Astaxanthin (AST) is a powerful antioxidant that occurs naturally in a wide variety of living organisms. Much experimental evidence has proved that AST has the function of eliminating oxygen free radicals and can protect organisms from oxidative damage. The present study was carried out to further investigate the neur...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.09.016
更新日期:2010-11-11 00:00:00
abstract::The neurotransmitter GABA exerts a biphasic effect on alpha-melanocyte-stimulating hormone (alpha-MSH) secretion from pars intermedia cells: GABA induces a rapid and transient stimulation followed by a sustained inhibition of alpha-MSH release. In the present study, we have investigated the effect of GABA on the elect...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91020-h
更新日期:1990-05-28 00:00:00
abstract::Initial studies found glutamate injury to murine spinal cultures (14-17 days in vitro) to reflect contributions of both NMDA and AMPA/kainate receptors. Subsequent experiments found the spinal cultures to be more sensitive than cortical cultures to injury from prolonged low level kainate exposures, and, unlike cortica...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00532-u
更新日期:1995-08-21 00:00:00
abstract::In previous studies on Alzheimer's patients it was shown that, in frontal and parietal locations, delta and theta responses of AD patients were greatly reduced. The present study analyzed coherence functions in these highly affected frontal and parietal areas. Visual sensory and event related coherences of patients wi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.08.054
更新日期:2010-10-21 00:00:00
abstract::Mammalian neostriatum is composed of two neurochemically and neuroanatomically defined compartments, called the patches and matrix. The present study concerns a search for neurochemical molecules involved in formation of the striatal compartments. Using the monoclonal antibody CR-50, we here disclose a transient expre...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)02136-8
更新日期:1999-12-11 00:00:00
abstract::Infusion of 1 microgram of carbachol, a potent cholinergic agonist, into the lateral septum of the urethane-anaesthetized rat systematically caused the induction of clear-cut hippocampal theta (theta). However, infusion of an equivalent amount of the drug into the hippocampus, close to the recording electrode, failed ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91551-3
更新日期:1993-12-24 00:00:00
abstract::The active and passive membrane properties of developing Purkinje neurons in control cultures and cultures chronically treated with 20 or 40 mM ethanol for 1 or 2 weeks were examined using whole-cell current-clamp techniques. The membrane properties were characterized by the features of the voltage responses evoked by...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90707-3
更新日期:1991-08-30 00:00:00
abstract::Previous electrophysiological experiments have shown that brain noradrenaline neurons in the locus ceruleus are activated by thermal cutaneous stimuli. In the present study a putative involvement of excitatory amino acids (EAA) in cutaneous LC activation was analyzed. Intraventricular administration of kynurenic acid ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91560-4
更新日期:1990-06-25 00:00:00
abstract::The light and electron microscopic localization of leucine-enkephalin-containing terminals in the facial nucleus of the rat were investigated by means of the peroxidase-antiperoxidase (PAP) immunocytochemical technique. By light microscopy, leucine-enkephalin-like immunoreactive (LEI) terminals were unevenly distribut...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90517-6
更新日期:1983-09-05 00:00:00
abstract::The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91305-9
更新日期:1987-09-22 00:00:00
abstract::The present experiments were aimed to determine the extent to which differentiated neuroblastoma cells may serve as a donor source for neural transplantation studies. Rodent-derived C1300 and human-derived LA-N-2 cells stained positively for choline acetyltransferase in vitro whether left untreated or rendered amitoti...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90182-x
更新日期:1987-08-04 00:00:00
abstract::Cultured cells derived from Tay-Sachs disease (TSD) fetal cerebellum were shown to accumulate GM2 ganglioside when compared with control cultures. In contrast, fibroblasts derived from TSD fetal lung do not contain GM2. GM2 was identified by thin-layer chromatography (TLC) and confirmed by gas-liquid chromatography (G...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)91052-0
更新日期:1976-07-23 00:00:00
abstract::Nitric oxide (NO) is an endothelium-derived relaxing factor and its main mechanism of action is activation of soluble guanylyl cyclase. NO and NO-related compounds have been reported to affect several neuronal functions in the central nervous system. In this study, we investigated the effects of NO donors (sodium nitr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00291-6
更新日期:1997-06-20 00:00:00
abstract::Event-related potentials (ERPs) were recorded using a large electrode array while subjects engaged in tasks designed to dissociate control from storage/maintenance processes in verbal working memory (WM). Increased ERP negativity (450-900 ms post-stimulus onset) over left frontal regions emerged only when required dyn...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.06.083
更新日期:2007-10-03 00:00:00
abstract::The effects of the intraventricular administration of aluminum chloride (AlCl3) on high affinity choline transport (HAChT) and norepinephrine concentration were examined in the hippocampus of the rat. Controlling for osmolarity and pH, the intraventricular administration of AlCl3 resulted in a dose-related reduction i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91121-9
更新日期:1989-10-02 00:00:00
abstract::Infusion of carbachol into the lateral ventricles of rats at rates of 400 or 2000 ng/h for 6 h produced dose-related natriuresis, kaliuresis, and water drinking but no consumption of hypertonic NaCl solution. Electrolyte excretion and water intake were maximal during the first 2 h, and no further increases occurred af...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90593-1
更新日期:1985-04-22 00:00:00
abstract::Aluminum (Al) concentrations of the rat frontal cortex, parietal cortex, and hippocampus were measured by atomic absorption spectroscopy 16 days after a unilateral intracerebroventricular injection of Na gluconate, Al gluconate, or the cholinotoxin AF64A. A fourth group of rats were injected with AF64A 6 days before i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90946-8
更新日期:1988-03-22 00:00:00
abstract::The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90342-8
更新日期:1987-05-05 00:00:00
abstract::Autism spectrum disorders (ASD) are associated with disturbances of neural connectivity. Functional connectivity between neural structures is typically examined within the context of a cognitive task, but also exists in the absence of a task (i.e., "rest"). Connectivity during rest is particularly active in a set of s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.11.057
更新日期:2010-02-08 00:00:00
abstract::An autoradiographic determination of the time of origin of the lateral motor columns (LMC) of the chick embryo has been made. The first motor neurons of the brachial LMC are born at stage 15; the earliest birthdates of lumbar LMC neurons are at stage 17. At least 95% of the motor neurons of both brachial and lumbar co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90416-4
更新日期:1977-08-26 00:00:00
abstract::The primary olfactory cortex of mouse embryos varying in age from the 13th to the 15th day of gestation is investigated with the aid of several techniques: Nissl and Golgi preparations, autoradiography and electron microscopy. It is observed that the earliest cells to complete their migrations are diffusely scattered ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90641-2
更新日期:1977-03-04 00:00:00
abstract::Ibogaine, an indolalkylamine, has been proposed for use in treating stimulant addiction. In the present study we sought to determine if ibogaine had any effects on the neurochemical and motor changes induced by D-amphetamine that would substantiate the anti-addictive claim. Ibogaine (40 mg/kg, i.p.) injected 19 h prio...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90745-u
更新日期:1992-05-01 00:00:00