Escapable and inescapable stress differentially alter extracellular levels of 5-HT in the basolateral amygdala of the rat.

abstract：:Using biochemical techniques we determined concentrations of the AMPA-selective glutamate receptor subunits GluR1 and GluR2/3 in the entorhinal cortex of patients with Alzheimer's disease pathology and age-matched controls. Tangle density was also determined in anatomically matched samples and correlated with GluR1 an...

journal_title：Brain research

authors： Yasuda RP,Ikonomovic MD,Sheffield R,Rubin RT,Wolfe BB,Armstrong DM

更新日期：1995-04-24 00:00:00

abstract：:alpha-Motoneurons innervating the triceps surae and short plantar muscles were stained intracellularly with horseradish peroxidase (HRP) in 0-44-day-old kittens and adult cats. The terminal arborizations of the recurrent axon collaterals in the spinal cord were studied in the light microscope (LM). The short plantar m...

journal_title：Brain research

authors： Cullheim S,Ulfhak B

更新日期：1985-01-01 00:00:00

abstract：:For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...

journal_title：Brain research

authors： Ding R,Asada H,Obata K

更新日期：1998-07-27 00:00:00

abstract：:Cytotoxic effects of L-glutamate and related compounds were investigated on rat glioma C6 cells in vitro. Within 12-24 h, addition of glutamate to the culture medium, resulted in degeneration of the C6 cells. The ED50 for glutamate-induced damage was about 4 mM. Seventeen structural analogues of glutamate, including a...

journal_title：Brain research

authors： Kato S,Higashida H,Higuchi Y,Hatakenaka S,Negishi K

更新日期：1984-06-15 00:00:00

abstract：:We investigated the effects of a novel Na(+)/H(+) exchanger-1 (NHE-1) inhibitor KR-33028 on glutamate excitotoxicity in cultured neuron cells in vitro and cerebral infarct in vivo by comparing its potency with that of zoniporide, a well-known, highly potent NHE-1 inhibitor. KR-33028 inhibited NHE-1 activation in a con...

journal_title：Brain research

authors： Lee BK,Lee DH,Park S,Park SL,Yoon JS,Lee MG,Lee S,Yi KY,Yoo SE,Lee KH,Kim YS,Lee SH,Baik EJ,Moon CH,Jung YS

更新日期：2009-01-12 00:00:00

abstract：:Stimuli such as noise or hypoxia can induce a release of ATP into the cochlear fluid spaces. At nanomolar concentrations, ATP affects neurotransmission and electrochemical regulation of sound transduction. At higher concentrations, ATP may exert cytotoxicity acting on specific P2X(7) receptor subunits, thus contributi...

journal_title：Brain research

authors： Vlajkovic SM,Vinayagamoorthy A,Thorne PR,Robson SC,Wang CJ,Housley GD

更新日期：2006-08-09 00:00:00

abstract：:To assess the role of androgen-dependent brain vasopressinergic transmission in the modulation of social recognition, castrated male rats which are deficient in vasopressin were implanted intracerebroventricularly with an Accurel collodion mini-device containing 10 micrograms vasopressin (AVP) whereas intact male rats...

journal_title：Brain research

authors： Bluthé RM,Dantzer R

更新日期：1992-02-14 00:00:00

abstract：:Pituitary adenylate cyclase-activating peptide (PACAP) is a 38-amino-acid polypeptide, first isolated from hypothalamus, which directly stimulates in vitro the production of cAMP as well as the release of several pituitary hormones, such as growth hormone and luteinizing hormone. In vivo, PACAP has been shown to stimu...

journal_title：Brain research

authors： Grinevich V,Fournier A,Pelletier G

更新日期：1997-10-31 00:00:00

abstract：:Horeradish peroxidase was injected at multiple sites in the mandibular and sublingual salivary glands in order to label the preganglionic salivatory neurons in the brain stem. The same injections resulted in retrograde labeling of the sympathetic and sensory neurons that project to these glands. Labeled fusiform and m...

journal_title：Brain research

authors： Chibuzo GA,Cummings JF

更新日期：1980-05-12 00:00:00

abstract：:Neuropeptide- and serotonin-like immunoreactivities were studied in the lumbar spinal cord of the cat after a longitudinal incision in the ventral funiculus. This lesion, which accomplishes a central axotomy of motoneurons, was accompanied by increased level of Met-enkephalin-like immunoreactivity in nerve endings in ...

journal_title：Brain research

authors： Lindå H,Cullheim S,Risling M,Arvidsson U,Mossberg K,Ulfhake B,Terenius L,Hökfelt T

更新日期：1990-11-26 00:00:00

abstract：:The duration of the sensitive period of the kitten visual cortex to the effects of monocular deprivation was explored by studies of the behavioral and physiological recovery from extended periods of monocular occlusion imposed from birth, and by examination of the physiological effects of a 3 month period of monocular...

journal_title：Brain research

authors： Cynader M,Timney BN,Mitchell DE

更新日期：1980-06-09 00:00:00

abstract：:Calretinin-immunoreactive structures in the anterior olfactory nucleus of the rat were studied using a polyclonal antibody, which does not cross-react with the highly homologous calcium-binding protein calbindin-D28k, and the avidin-biotin-peroxidase technique. Calretinin-immunopositive neurons were found in all regio...

journal_title：Brain research

authors： García-Ojeda E,Alonso JR,Briñón JG,Rogers J,Weruaga E,Arévalo R,Aijón J

更新日期：1998-04-06 00:00:00

abstract：:Recent research has shown that familiarity contributes to associative memory when the to-be-associated stimuli are unitized during encoding. However, the specific processes underlying familiarity-based recognition of unitized representations are still indefinite. In this study, we present electrophysiologically dissoc...

journal_title：Brain research

authors： Wiegand I,Bader R,Mecklinger A

更新日期：2010-11-11 00:00:00

abstract：:In the present study, the role of medial septal receptors in behaviour-induced increase in acetylcholine (ACh) release in hippocampus was investigated using dual-probe microdialysis in combination with a simple behavioural procedure. gamma-Aminobutyric acid (GABA) and glutamate receptor agonists and antagonists were a...

journal_title：Brain research

authors： Moor E,Schirm E,Jacsó J,Westerink BH

更新日期：1998-04-06 00:00:00

abstract：:Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study effects of minocycline, an anti-inflammatory agent, alone or in combination with mild hypothermia, on focal embolic brain ischemia have been examined. Focal ischemic injury was induced by embolizing a ...

journal_title：Brain research

authors： Wang CX,Yang T,Shuaib A

更新日期：2003-02-14 00:00:00

abstract：:Thyroid hormone effects on brain somatostatin-like immunoreactivity (SRIF-LI) were studied in an in vitro model system. Serum was removed from the nutrient culture medium of fetal day-18 rat cerebral cortex cells maintained in primary, long-term, dispersed monolayer culture. Chronic administration of either T3 or T4 i...

journal_title：Brain research

authors： Peterfreund RA,Sawchenko PE,Vale W

更新日期：1985-03-04 00:00:00

abstract：:Glucocorticoids exacerbate aging-induced cell death, but relatively little is known about other CNS effects in senescence. We examined noradrenergic/adenylyl cyclase signaling in the cerebellum, which is a brain region that is susceptible to deterioration of synaptic function in aging. Aged control rats had increased ...

journal_title：Brain research

authors： Slotkin TA,Zhang J,McCook EC,Seidler FJ

更新日期：1998-08-03 00:00:00

abstract：:In the present study we have examined the effects of changes in potassium and calcium concentration on the early adaptation of the slowly adapting stretch receptor of the crayfish using intracellular recordings including the potential clamp technique. This was because previous studies had suggested that the early adap...

journal_title：Brain research

authors： Ottoson D,Swerup C

更新日期：1985-06-10 00:00:00

abstract：:Radioautography was used to study the intraneuronal distribution of [3H]-serotonin (5-HT) and/or its derivatives selectively taken up by the olfactory bulb (OB) serotonergic terminals and subsequently transported to their parent cell bodies in the midbrain raphe nuclei. This was done 24 h after injection of [3H]5-HT i...

journal_title：Brain research

authors： Araneda S,Gamrani H,Font C,Calas A,Pujol JF,Bobillier P

更新日期：1980-09-08 00:00:00

abstract：:Intracerebral injections of 6-hydroxydopamine (6-OHDA) which produce deficits in locomotor behaviour and motor performance cause localized accumulation of monoamines as well as depletion of central catecholamines (CA). To determine whether the localized increases in monoamines could be contributing to the behavioural ...

journal_title：Brain research

authors： Willis GL,Smith GC,McGrath BP

更新日期：1983-05-05 00:00:00

abstract：:'Spontaneous' and visually evoked action potentials were recorded from single neurons in cytoarchitectonic area 17 (striate cortex, area V1) of anaesthetized and immobilized cats, prior to, during and after brief reversible inactivation of the ipsilateral postero-temporal visual (PTV) cortex (presumed homologue of pri...

journal_title：Brain research

authors： Huang JY,Wang C,Dreher B

更新日期：2007-03-23 00:00:00

abstract：:This study examined the hypothesis that the subfornical organ (SFO), a circumventricular organ with both osmosensitive elements and dipsogenic receptors for circulating angiotensin (ANG) II, is important for the water drinking response that follows an intragastric (ig) load of hypertonic NaCl. A 2-ml saline load was a...

journal_title：Brain research

authors： Starbuck EM,Fitts DA

更新日期：1998-06-08 00:00:00

abstract：:This study investigated the effects of the calcium channel blockers nicardipine, calcicludine, omega-conotoxin GVIA, omega-agatoxin IVA, SNX-482, and NiCl on spontaneous muscle action potential of a rat spinal cord-muscle co-culture system. Spontaneous muscle action potential of the innervated muscle cells was blocked...

journal_title：Brain research

authors： Taguchi K,Shiina M,Shibata K,Utsunomiya I,Miyatake T

更新日期：2005-02-09 00:00:00

abstract：:In the present study, the light responses of ganglion cells to chromatic stimulus were recorded from isolated retina of neonatal chick. It was found that for some non-color-opponent ganglion cells, the spatiotemporal patterns of the cells' light responses were related to the chromatic information that they received. W...

journal_title：Brain research

authors： Zhou Y,Chen AH,Gong HQ,Liang PJ

更新日期：2005-10-12 00:00:00

abstract：:A novel and convenient assay was used to determine the effect of recombinant Interleukin-2 (IL-2) on the function of the blood-brain barrier (BBB). The assay is based on a variant of the West Nile virus, WN-25, which had lost its neuroinvasiveness but not its neurovirulence. WN-25, when injected intravenously, can cau...

journal_title：Brain research

authors： Kobiler D,Lustig S,Gozes Y,Ben-Nathan D,Akov Y

更新日期：1989-09-04 00:00:00

abstract：:In freely-moving female rats the effects of intraventricular infusion of norepinephrine (NE) on multiunit activity (MUA) were examined in the Diagonal Band of Broca (DBB), medial preoptic area (MPOA) and anterior hypothalamic area (AHA), regions containing neurons producing luteinizing hormone-releasing hormone (LHRH)...

journal_title：Brain research

authors： Leung PC,Whitmoyer DI,Arendash GW,Sawyer CH

更新日期：1981-12-07 00:00:00

abstract：:Nitric oxide (NO) is a neuronal messenger that it is thought to be involved in the nociceptive transmission modulation. The activity of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) was shown to be identical to NOS activity in the brain. Since the periaqueductal gray matter (PAG) plays an important ...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1998-05-18 00:00:00

abstract：:A large body of evidence shows that methamphetamine (METH) causes sustained damage to the brain in animal models and human METH users. In chronic users there are indications of cognitive and motor deficits. Striatal neuropeptides are in a position to modulate the neurochemical effects of METH and consequently striatal...

journal_title：Brain research

authors： Afanador L,Mexhitaj I,Diaz C,Ordonez D,Baker L,Angulo JA

更新日期：2013-05-13 00:00:00

abstract：:Glucose modulates substantia nigra (SN) dopamine (DA) neuronal activity and GABA axon terminal transmitter release by actions on an ATP-sensitive potassium channel (K(ATP)). Here, the effect of altering SN glucose levels on striatal DA release was assessed by placing microdialysis probes into both the SN and striatum ...

journal_title：Brain research

authors： Levin BE

更新日期：2000-08-25 00:00:00

abstract：:The protective activity of trimetazidine (TMZ) against cochlear neurotoxicity induced by intraperitoneal and intracochlear administration of kainic acid (KA) has been analyzed. The amplitude of the CAP N1 wave was significantly higher in KA rats pretreated with TMZ, independently of the administration route, than in t...

journal_title：Brain research

authors： Gil-Loyzaga P,Hernández E,Carricondo F,Simón F,Poch-Broto J

更新日期：1999-04-24 00:00:00