Changes in the central canal area of immature rats following spinal cord injury.

abstract：:The role of astrocytes in glutamate toxicity has been controversial. Here, we show that astrocytes in neuron-astrocyte co-cultures increased neuronal sensitivity to chronic glutamate exposure but not to acute exposure. Enhanced neuronal toxicity by chronic exposure was dependent on astrocyte cell numbers. A reduced ge...

journal_title：Brain research

authors： Ha JS,Dho SH,Youm TH,Kwon KS,Park SS

更新日期：2014-11-24 00:00:00

abstract：:Systemic administration of the protein synthesis inhibitor, cycloheximide, induced both phase advances and phase delays in the circadian rhythm of wheel-running activity in hamsters (Mesocricetus auratus) maintained in constant darkness or constant light. The magnitude and direction of the phase shifts were dependent ...

journal_title：Brain research

authors： Wollnik F,Turek FW,Majewski P,Takahashi JS

更新日期：1989-09-04 00:00:00

abstract：:Available evidence suggests that regular, moderate-intensity exercise has beneficial effects on neural health, perhaps including neuroprotection. To evaluate this idea further, we compared the severity of kainate-induced neuronal loss in exercised versus sedentary female rats. Stereological estimations of neuron numbe...

journal_title：Brain research

authors： Ramsden M,Berchtold NC,Patrick Kesslak J,Cotman CW,Pike CJ

更新日期：2003-05-09 00:00:00

abstract：:This study examined the spatial organization of corticotropin-releasing factor (CRF) immunopositive climbing fibers in the mouse cerebellum by whole mount immunohistochemistry. A striking pattern of parasagittal stripes of CRF staining was revealed. Cryosections of whole mount CRF stained cerebellum showed that anti-C...

journal_title：Brain research

authors： Sawada K,Fukui Y,Hawkes R

更新日期：2008-07-30 00:00:00

abstract：:Dynamin-1 is a multi-domain GTPase that is crucial for the fission stage of synaptic vesicle recycling and vesicle trafficking. In this study, we constructed prokaryotic expression plasmids for the four functional domains of dynamin-1, which are pGEX-4T-2-PH, pGEX-4T-2-PRD, pGEX-4T-2-GED and pGEX-4T-2-GTPase. Glutathi...

journal_title：Brain research

authors： Zhang C,Omran AG,He F,Deng X,Wu L,Peng J,Yin F

更新日期：2014-01-16 00:00:00

abstract：:The ability of hippocampal serotonergic (5-HT) axons to proliferate in response to damage by para-chloroamphetamine (PCA) was examined in this study. Synaptosomal uptake of 5-HT in the hippocampal formation was decreased to 40% of control 3 days after systemic administration of PCA. Six weeks after PCA, uptake values ...

journal_title：Brain research

authors： Haring JH,Meyerson L,Hoffman TL

更新日期：1992-04-17 00:00:00

abstract：:Aquaporin-4 (AQP4), the prominent water channel in the brain, is particularly concentrated in astrocytic endfeet membranes lining the capillaries and the pia. This localisation pattern makes it well suited to regulate the flow of water and the homeostasis of the interstitial fluid surrounding the neurons. Using immuno...

journal_title：Brain research

authors： Medici V,Frassoni C,Tassi L,Spreafico R,Garbelli R

更新日期：2011-01-07 00:00:00

abstract：:The subfornical organ of the brain has a role in the regulation of fluid balance in higher animals. In this study the effects of salt loading and water deprivation on specific proteins in this organ were investigated. For 4 days, 3 groups of rats were given an appropriate fluid diet (control, 2% NaCl and water deprive...

journal_title：Brain research

authors： Santer DM,Heydorn WE,Creed GJ,Klein DC,Jacobowitz DM

更新日期：1986-04-30 00:00:00

abstract：:ASIC3-immunoreactivity (ir) was examined in the rat vagal and glossopharyngeal sensory ganglia. In the jugular, petrosal and nodose ganglia, 24.8%, 30.8% and 20.6% of sensory neurons, respectively, were immunoreactive for ASIC3. These neurons were observed throughout the ganglia. A double immunofluorescence method dem...

journal_title：Brain research

authors： Fukuda T,Ichikawa H,Terayama R,Yamaai T,Kuboki T,Sugimoto T

更新日期：2006-04-07 00:00:00

abstract：:Coupling between lumbar motoneurons in the isolated frog spinal cord was studied by using intracellular recordings and intracellular injections of Lucifer Yellow CH. Physiological studies revealed intra- and intersegmental, short latency electrical interactions between many motoneurons. Injections of Lucifer Yellow in...

journal_title：Brain research

authors： Brenowitz GL,Collins WF 3rd,Erulkar SD

更新日期：1983-09-12 00:00:00

abstract：:The blood-brain interface in elasmobranchs was examined using physiological and anatomical techniques. Electrolyte analyses of plasma and cerebrospinal fluid (CSF) in control fish and in fish with elevated plasma cation concentration (Ca, Mg or K) demonstrated homeostasis of CSF calcium and magnesium concentrations in...

journal_title：Brain research

authors： Bundgaard M,Cserr H

更新日期：1981-12-07 00:00:00

abstract：:Two high molecular weight surface glycoproteins of cerebellar cells which are selectively labeled by lactoperoxidase-catalyzed iodination of monolayer cultures from the developing mouse cerebellum, have been identified and partially characterised. Both molecules, called peak 2 and peak 3 proteins, were the major glyco...

journal_title：Brain research

authors： Goridis C,Hirsch M,Dossetto M,Baechler E

更新日期：1980-01-27 00:00:00

abstract：:Aging is accompanied by an impairment of associative memory. The medial temporal lobe and fronto-striatal network, both involved in associative memory, are known to decline functionally and structurally with age, leading to the so-called associative binding deficit and the resource deficit. Because the MTL and fronto-...

journal_title：Brain research

authors： Meulenbroek O,Kessels RP,de Rover M,Petersson KM,Rikkert MG,Rijpkema M,Fernández G

更新日期：2010-02-22 00:00:00

abstract：:Previous electrophysiological as well as imaging research has contributed to the understanding of impairments in attention, executive functions, and memory in patients with attention-deficit/hyperactivity disorder (ADHD). However, there is a lack of studies investigating ADHD related differences in the gamma range of ...

journal_title：Brain research

authors： Lenz D,Krauel K,Schadow J,Baving L,Duzel E,Herrmann CS

更新日期：2008-10-15 00:00:00

abstract：:The subfornical organ, along with other regions of the lamina terminalis, may contain osmoreceptors and is likely to be a site of action of blood-borne angiotensin II. The neural pathways by which these stimuli lead to vasopressin secretion, have been suggested to extend from the subfornical organ to hypothalamic site...

journal_title：Brain research

authors： Oldfield BJ,Hards DK,McKinley MJ

更新日期：1991-08-30 00:00:00

abstract：:The response of trunk neural crest cells taken from precise levels of the neural axis and cultured together with adjacent somites to Brain-derived neurotrophic factor (BDNF), was examined in cultures grown in a chemically defined medium. In control cultures, the number of neural crest-derived neurons expressing the HN...

journal_title：Brain research

authors： Kalcheim C,Gendreau M

更新日期：1988-06-01 00:00:00

abstract：:Intraperitoneal (i.p.) administration of sulfated CCK octapeptide (CCK-8S) has been shown to induce changes in neuronal activity in the nucleus of the solitary tract (NTS) and area postrema (AP), sensory parts of the dorsal vagal complex (DVC), and in the paraventricular nucleus of the hypothalamus (PVN), as determine...

journal_title：Brain research

authors： Mönnikes H,Lauer G,Arnold R

更新日期：1997-10-03 00:00:00

abstract：OBJECTIVE:Recent research has shown dissociation between changes in brain and muscle signals during voluntary muscle fatigue, which may suggest weakening of functional corticomuscular coupling. However, this weakening of brain-muscle coupling has never been directly evaluated. The purpose of this study was to address t...

journal_title：Brain research

authors： Yang Q,Fang Y,Sun CK,Siemionow V,Ranganathan VK,Khoshknabi D,Davis MP,Walsh D,Sahgal V,Yue GH

更新日期：2009-01-23 00:00:00

abstract：:1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) was used to lesion the substantia nigra of rodents to look for changes in various animal models of epilepsy and seizures. MPTP, acutely administered to C57BL/6J mice, could cause seizures at high doses and enhanced maximal electroshock seizures at lower doses. Older ...

journal_title：Brain research

authors： Van Ness PC,Olsen RW,Verity MA

更新日期：1989-12-18 00:00:00

abstract：:Synaptosomes prepared from fresh human cerebral cortex were shown to be morphologically similar to those from other species. On incubation, they took up oxygen at a high and linear rate and accumulated potassium against a concentration gradient. In response to depolarization by raised extracellular K+ or addition of v...

journal_title：Brain research

authors： Dodd P,Hardy JA,Oakley AE,Strong AJ

更新日期：1981-11-16 00:00:00

abstract：:In extracellular recordings from chloral hydrate anesthetized rats the 5-HT3 antagonist, BRL 46470A, failed to prevent or reverse the increase in dopamine cell firing rate produced by systemic or iontophoretically applied morphine. A second 5-HT3 antagonist, tropesitron, was similarly found to be ineffective in antago...

journal_title：Brain research

authors： Gifford AN,Wang RY

更新日期：1994-02-28 00:00:00

abstract：:This study shows that permanent cell lines can be established from rat and mouse brain by direct tissue culture methodology without the aid of exogenous chemical or viral transforming agents. These cells were derived from specific areas of the brain, such as the cerebellum and hippocampus, at chosen times during fetal...

journal_title：Brain research

authors： Bulloch K,Stallcup WB,Cohn M

更新日期：1977-10-21 00:00:00

abstract：:Previous electrophysiological experiments have shown that brain noradrenaline neurons in the locus ceruleus are activated by thermal cutaneous stimuli. In the present study a putative involvement of excitatory amino acids (EAA) in cutaneous LC activation was analyzed. Intraventricular administration of kynurenic acid ...

journal_title：Brain research

authors： Hajós M,Engberg G

更新日期：1990-06-25 00:00:00

abstract：:The presence of corticotropin releasing factor (CRF)-immunoreactive nerve fibers and cell bodies in the spinal cord is demonstrated. Immunopositive fibers were found in the lateral column of the white matter, in laminae I, V-VII, X, and in the intermediolateral column of the spinal cord. Complete transection of the sp...

journal_title：Brain research

authors： Merchenthaler I,Hynes MA,Vigh S,Shally AV,Petrusz P

更新日期：1983-09-26 00:00:00

abstract：:Recent evidence indicates that the superior colliculus (SC), in addition to its functions in sensory detection, also participates in controlling the generalized activation state of the forebrain, as measured by the electroencephalogram (EEG) or electrocorticogram (ECoG). The mechanisms by which the SC modulates forebr...

journal_title：Brain research

authors： Dringenberg HC,Vanderwolf CH,Noseworthy PA

更新日期：2003-02-21 00:00:00

abstract：:Endothelins are potent vasoconstrictors and signaling molecules. Their effects are broad, impacting processes ranging from neurovascular and cardiovascular health to cell migration and survival. In stroke, traumatic brain injury or subarachnoid hemorrhage, endothelin-1 (ET-1) is induced resulting in cerebral vasospasm...

journal_title：Brain research

authors： Bickford JS,Ali NF,Nick JA,Al-Yahia M,Beachy DE,Doré S,Nick HS,Waters MF

更新日期：2014-11-07 00:00:00

abstract：:Parkin Co-Regulated Gene (PACRG) is a novel gene that is oriented in a head-to-head array with parkin, and expression of the two genes is regulated by a shared bi-directional promoter. Mutations in parkin are the most common cause of early-onset autosomal recessive Parkinson's disease, however the function of PACRG an...

journal_title：Brain research

authors： Brody KM,Taylor JM,Wilson GR,Delatycki MB,Lockhart PJ

更新日期：2008-03-27 00:00:00

abstract：:The aim of this work was to investigate the modulation of the cardiovascular effects of neuropeptide Y (NPY) in the nucleus tractus solitarii (NTS) by angiotensin II (Ang II) and to determine the NPY receptor subtype involved in this modulation. Anesthesized Sprague-Dawley rats received microinjections in the NTS of A...

journal_title：Brain research

authors： Díaz-Cabiale Z,Fuxe K,Coveñas R,González-Barón S,Narváez JA

更新日期：2003-09-05 00:00:00

abstract：:Computer-assisted morphometrics were used to characterize mature somatodendritic architecture in Golgi-stained neurons of the entopeduncular nucleus (EN) of the adult cat. Only one form of adult EN neuron was apparent and characterized by common features including: relatively large conical somata, long aspiny and mode...

journal_title：Brain research

authors： Dvergsten CL,Hull CD,Levine MS,Adinolfi AM,Fisher RS,Buchwald NA

更新日期：1986-06-11 00:00:00

abstract：:Double-pulse stimulation of the perforant path input to the dentate gyrus was used in the following experiments to produce paired pulse depression in that site. This effect provided an estimate of GABA-mediated recurrent inhibition. The depression was enhanced by drugs that facilitate or mimic GABA action and attenuat...

journal_title：Brain research

authors： Tuff LP,Racine RJ,Adamec R

更新日期：1983-10-24 00:00:00