Abstract:
:Synaptosomes prepared from fresh human cerebral cortex were shown to be morphologically similar to those from other species. On incubation, they took up oxygen at a high and linear rate and accumulated potassium against a concentration gradient. In response to depolarization by raised extracellular K+ or addition of veratrine, they showed increased respiration, lowered tissue potassium, and enhanced release of glutamate, aspartate and GABA. The preparation may be of value for studies of neurological disorders.
journal_name
Brain Resjournal_title
Brain researchauthors
Dodd P,Hardy JA,Oakley AE,Strong AJdoi
10.1016/0006-8993(81)90871-4subject
Has Abstractpub_date
1981-11-16 00:00:00pages
419-25issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(81)90871-4journal_volume
224pub_type
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