The effect of raphe lesion on sleep in the rat.

abstract：:The effects of indomethacin (10 mg/kg) on the release of the transmitter amino acids, glutamate, aspartate, GABA, and of the purines, adenosine and inosine, from the cerebral cortex was studied in a four-vessel occlusion rat model of cerebral ischemia/reperfusion. In comparison with the control group, indomethacin sig...

journal_title：Brain research

authors： Phillis JW,Smith-Barbour M,Perkins LM,O'Regan MH

更新日期：1994-08-01 00:00:00

abstract：:In vitro quantitative autoradiography of high-affinity [3H]desmethylimipramine (DMI) binding sites was performed on 24 human brains postmortem. Highest densities of binding sites were found in portions of the amygdala, the granular layer of the dentate gyrus, the pyramidal layer of CA4. Next, in descending order were ...

journal_title：Brain research

authors： Gross-Isseroff R,Israeli M,Biegon A

更新日期：1988-07-19 00:00:00

abstract：:Previously brain norepinephrine (NE) neurons in the locus coeruleus (LC) have been shown to respond profoundly to external, environmental stimuli and are thought to be involved in behavioral functions such as vigilance, alarm and anxiety reactions to novel and, especially, threatening stimuli. Here we have used electr...

journal_title：Brain research

authors： Elam M,Thorén P,Svensson TH

更新日期：1986-06-04 00:00:00

abstract：:The effect of bilateral lesion of the accessory olfactory bulb (AOB) on the mating-induced enhancement of sexual receptivity was investigated in ovariectomized (OVX) female rats. Lesions of the AOB significantly reduced the lordosis-to-mount (L/M) ratio in mating tests conducted 20 to 50 days after the lesion but L/M ...

journal_title：Brain research

authors： Dudley CA,Moss RL

更新日期：1994-04-11 00:00:00

abstract：:Immunohistochemistry was used to examine the co-occurrence of nicotinic acetylcholine receptor subunits with calcium-binding proteins in ganglion cells of the chick retina. The alpha3 subunit was rarely observed in ganglion cells containing calbindin, calretinin, or parvalbumin. On the other hand, the alpha8 subunit w...

journal_title：Brain research

authors： Araki CM,Pires RS,Britto LR,Lindstrom JM,Karten HJ,Hamassaki-Britto DE

更新日期：1997-11-07 00:00:00

abstract：:The binding characteristics of [3H]cytisine, a putative CNS nicotinic receptor ligand, were examined in 4 regions of the human brain. [3H]Cytisine was found to bind non-cooperatively with high affinity to a single site in tissue homogenates and to exhibit low non-specific association. The binding characteristics of th...

journal_title：Brain research

authors： Hall M,Zerbe L,Leonard S,Freedman R

更新日期：1993-01-08 00:00:00

abstract：:To determine whether postmitotic neurons can be immortalized by oncogenic transduction, we used two approaches involving conditional expression of a temperature-sensitive SV40 large T antigen (Tts). Initially, Tts was introduced into E17 rat embryonal hippocampal cells that were then cultured at the non-permissive tem...

journal_title：Brain research

authors： Eves EM,Kwon J,Downen M,Tucker MS,Wainer BH,Rosner MR

更新日期：1994-09-12 00:00:00

abstract：:Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This...

journal_title：Brain research

authors： Garnett S,Firnau G,Nahmias C,Chirakal R

更新日期：1983-11-28 00:00:00

abstract：:Morphological, electrophysiological and behavioral studies were carried out in cats after unilateral kainic acid injection in the substantia nigra. A forced contralateral head turning and compulsive circling was observed after surgery. Fifteen days after, when asymmetry disappeared, apomorphine induced an ipsilateral ...

journal_title：Brain research

authors： Motles E,Saavedra H,Infante C,Leiva J,Gonzalez M

更新日期：1987-03-03 00:00:00

abstract：:Chronic administration of guanethidine to adult rats induces a selective autoimmune adrenergic neuropathy. Physiological and biochemical features of this disorder in the peripheral nervous system were explored in young adult Sprague-Dawley rats given daily intraperitoneal guanethidine monosulfate for 5 weeks. Control ...

journal_title：Brain research

authors： Zochodne DW,Ward KK,Low PA

更新日期：1988-09-27 00:00:00

abstract：:The reactivity of dopaminergic (DA) terminals in the nucleus accumbens was investigated in male rats submitted to tail-pinch or various social interactions. The DA activity was assessed by measurement of the presynaptic metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) by using differential pulse voltammetry in free m...

journal_title：Brain research

authors： Louilot A,Le Moal M,Simon H

更新日期：1986-11-12 00:00:00

abstract：:We examined the effect of CP-154,526 on cardiovascular changes elicited in conscious rabbits by stressful stimuli (loud sound, cage move, pinprick, formaldehyde vapour and air-jet stress). CP-154,526 substantially reduced pressor and heart rate responses to these stimuli (both vagally and sympathetically mediated), an...

journal_title：Brain research

authors： Nalivaiko E,Blessing WW

更新日期：2004-08-13 00:00:00

abstract：:In rat models of absence epilepsy, epileptic spike-wave discharges appeared in EEG spontaneously, and the incidence of epileptic activity increases with age. Spike-wave discharges and sleep spindles are known to share common thalamo-cortical mechanism, suggesting that absence seizures might affect some intrinsic prope...

journal_title：Brain research

authors： Sitnikova E,Hramov AE,Grubov V,Koronovsky AA

更新日期：2014-01-16 00:00:00

abstract：:The particular vulnerability of hippocampal CA3/CA4 neurons to intracerebroventricularly administered kainate did not occur in rats until postnatal day 16. Glutamate applied in the same way failed to show comparable neurodegenerative signs, even when administered in large doses to adult animals. Alternatively, both ka...

journal_title：Brain research

authors： Wolf G,Keilhoff G

更新日期：1984-05-01 00:00:00

abstract：:Previous immunocytochemical studies have shown immunological differences between neurofilaments in axons and those in dendrites and perikarya of many mature neuron types: it is now known that non-phosphorylated epitopes are normally seen in cell bodies and dendrites of mature neurons, whereas phosphorylated epitopes a...

journal_title：Brain research

authors： Shaw G,Winialski D,Reier P

更新日期：1988-09-20 00:00:00

abstract：:Structures of the medial temporal lobes are recognized to play a central role in memory processing and to be the primary sites of deterioration in Alzheimer disease (AD). Mild cognitive impairment (MCI) represents potentially an intermediate state between normal aging and AD. Proton magnetic resonance spectroscopy (MR...

journal_title：Brain research

authors： Chantal S,Braun CM,Bouchard RW,Labelle M,Boulanger Y

更新日期：2004-04-02 00:00:00

abstract：:Patches excised from fields CA1 and CA3 of the hippocampus were used to study AMPA receptor responses to repetitive application of brief pulses of agonist. AMPA receptors in field CA1 exhibited a larger degree of paired-pulse depression and a slower recovery rate from desensitization than those from CA3 patches. Respo...

journal_title：Brain research

authors： Arai A,Lynch G

更新日期：1996-04-15 00:00:00

abstract：:Myelin is probably one of the most fascinating and innovative biological acquisition: a glia plasma membrane tightly wrapped around an axon and insulating it. Chondrichthyans (cartilaginous fishes) form a large group of vertebrates, and they are among oldest extant jawed vertebrate lineage. It has been known from stud...

journal_title：Brain research

authors： de Bellard ME

更新日期：2016-06-15 00:00:00

abstract：:Binding sites of atrial natriuretic peptide in the cerebral microvessels and choroid plexus of spontaneously hypertensive rats (SHR) and Wistar Kyoto control rats (WKY) were measured. In the microvessels, the number of ANP binding sites was lower in SHR than WKY, but there was no difference in affinity of binding site...

journal_title：Brain research

authors： Okazaki M,Kobayashi H,Kuroiwa A,Izumi F

更新日期：1990-06-04 00:00:00

abstract：:The importance of Na+/Ca2+ exchangers in the regulation of the physiological and pathological functions of the nervous system has been widely recognized. In this study, we used primary cultured E14.5 cortical neurons as a model system to study the possible roles of the reverse mode Na+/Ca2+ exchange activity in neurot...

journal_title：Brain research

authors： Wu MP,Kao LS,Liao HT,Pan CY

更新日期：2008-03-27 00:00:00

abstract：:Sheep with guide tubes implanted over the brain lateral ventricles, in order to facilitate episodic sampling of cerebrospinal fluid (CSF), were used to determine the effects of increasing cranial blood osmolality or electroconvulsive shock (ECS) on the permeability of the blood-brain barrier (BBB) to zinc. Zinc acetat...

journal_title：Brain research

authors： Blair-West JR,Denton DA,Gibson AP,McKinley MJ

更新日期：1990-01-15 00:00:00

abstract：:The rat hippocampus contains an acidic macromolecular neurotrophic factor (NTF) which supports the survival of cultured chick ciliary ganglion cells. Hippocampal NTF increases approximately 2-fold from birth to adulthood with no further change with aging. Disruption of extrinsic inputs to the hippocampus from the ento...

journal_title：Brain research

authors： Heacock AM,Schonfeld AR,Katzman R

更新日期：1986-01-22 00:00:00

abstract：:To study the regulation of hypothalamic vasopressin (VP) and oxytocin (OT) gene expression in relation to the development of hypertension, levels of VP mRNA and OT mRNA were determined in spontaneously hypertensive rats (SHR). Differences in VP and OT mRNA content of the supraoptic nucleus (SON) and paraventricular nu...

journal_title：Brain research

authors： van Tol HH,van den Buuse M,de Jong W,Burbach JP

更新日期：1988-12-01 00:00:00

abstract：:An in vitro radioenzymatic assay and purification procedure by thin-layer chromatography were used to study the metabolism of dihydrotestosterone (DHT) into 3 alpha- and 3 beta-androstanediols by the brain and cloacal gland of Japanese quail. Kinetic studies showed that these 2 metabolites are produced in a linear fas...

journal_title：Brain research

authors： Deviche P,Delville Y,Balthazart J

更新日期：1987-09-22 00:00:00

abstract：:Electrophysiological recordings were made from afferent nerve fibres supplying slowly adapting type I (SA I) cutaneous mechano-receptors in the cat during application of mechanical stimuli (20 mN constant force, 0.2 s rise time and 2 s plateau phase, every 30 s). Close arterial infusion of neomycin (2.5 mg/min for 5 m...

journal_title：Brain research

authors： Baumann KI,Hamann W,Leung MS

更新日期：1986-07-02 00:00:00

abstract：:Recent evidence has suggested that cholecystokinin (CCK) may act as a physiological opiate antagonist. Both the overlap of CCK and opiate systems within the central nervous system and the fact that exogenous CCK can antagonize opiate analgesia suggest that endogenous CCK systems interact with opiate-mediated pain inhi...

journal_title：Brain research

authors： Watkins LR,Kinscheck IB,Mayer DJ

更新日期：1985-02-18 00:00:00

abstract：:The trace elemental concentrations, including iron, in the substantia nigra (SN) of a 6-OHDA induced rat model of Parkinson's disease were measured using nuclear microscopy. Only rats that exhibited amphetamine induced rotation of more than 7 turns/min were used. The results showed that the iron levels were significan...

journal_title：Brain research

authors： He Y,Thong PS,Lee T,Leong SK,Shi CY,Wong PT,Yuan SY,Watt F

更新日期：1996-09-30 00:00:00

abstract：:Antisense oligodeoxynucleotides (ODNs) are used for the selective inhibition of gene expression. Antisense ODNs are promising tools for the investigation of physiological implications of proteins in the central nervous system of rodents in vivo. We have previously demonstrated that a phosphorothioate antisense ODN to ...

journal_title：Brain research

authors： Karle J,Witt MR,Nielsen M

更新日期：1997-08-08 00:00:00

abstract：:The potential shifts (delta Vo) associated with spreading depression (SD) were analysed with the help of multiple extracellular recording and ion-selective microelectrodes in the CA1 region of the dorsal hippocampus of anesthetized rats. Recurrent waves of SD were induced by perfusing high K+ solution through microdia...

journal_title：Brain research

authors： Herreras O,Somjen GG

更新日期：1993-05-07 00:00:00

abstract：:Temporal changes in cholinergic functions following transient cerebral ischemia (10 min) were studied in the hippocampus of awake unrestrained gerbils using in vivo microdialysis. These data were compared with the results for temporal change in the area of each CA1 cell soma, measured with a microcomputer imaging devi...

journal_title：Brain research

authors： Ishimaru H,Takahashi A,Ikarashi Y,Maruyama Y

更新日期：1994-03-07 00:00:00