Reduced responsiveness of touch (SA I) receptors in the cat following close arterial infusion of neomycin.

Abstract:

:Electrophysiological recordings were made from afferent nerve fibres supplying slowly adapting type I (SA I) cutaneous mechano-receptors in the cat during application of mechanical stimuli (20 mN constant force, 0.2 s rise time and 2 s plateau phase, every 30 s). Close arterial infusion of neomycin (2.5 mg/min for 5 min) strongly depressed the responsiveness of SA I receptors. A direct effect on the receptor is thought to be the mode of action.

journal_name

Brain Res

journal_title

Brain research

authors

Baumann KI,Hamann W,Leung MS

doi

10.1016/0006-8993(86)91201-1

subject

Has Abstract

pub_date

1986-07-02 00:00:00

pages

160-2

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(86)91201-1

journal_volume

377

pub_type

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