Abstract:
:In teleosts, the fasciculus medialis tractus optici departs the optic tract and follows an aberrant path towards the midbrain tectum. To determine the retinal origin of the fascicle, horseradish peroxidase was injected into localized lesions of either the optic nerve or the retina. The fasciculus medialis axons of adult goldfish derive selectively from ganglion cells residing in the dorsotemporal portion of the central retina. The fasciculus medialis appears to be an integral part of the chronotopic ordering of fibers in the optic tract.
journal_name
Brain Resjournal_title
Brain researchauthors
Fraley SM,Sharma SCdoi
10.1016/0006-8993(85)90082-4subject
Has Abstractpub_date
1985-07-01 00:00:00pages
392-5issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(85)90082-4journal_volume
337pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The synchronization of circadian rhythms in sleep, endocrine and metabolic functions with the environmental light cycle is essential for health, and dysfunction of this synchrony is thought to play a part in the development of many neurological disorders. There is a demonstrable need to develop new therapeutics for th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.08.034
更新日期:2014-10-17 00:00:00
abstract::Saccadic eye tracking was studied in a monkey given i.v. injections of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The Parkinson-like symptoms which appeared in the animal's general motor behavior (akinesia, bradykinesia, hypokinesia) were also observed in its eye tracking. Similar oculomotor deficits are see...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90049-1
更新日期:1986-09-24 00:00:00
abstract::Subnanomolar concentrations of melatonin inhibit cyclic AMP and cyclic GMP accumulation in neonatal rat anterior pituitary stimulated in vitro with luteinizing-hormone releasing-hormone. Melatonin also inhibited forskolin-stimulated cyclic AMP accumulation in pars tuberalis. Inhibition of cyclic AMP accumulation is sp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90129-7
更新日期:1989-12-25 00:00:00
abstract::We measured the effects of acute or chronic administration of fenfluramine and phentermine, alone or in combination, on brain dopamine and serotonin release into striatal dialysates of freely moving rats. Samples collected every 30 min were assayed in a single run by high-pressure liquid chromatography. Acute or chron...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)01003-8
更新日期:1998-11-30 00:00:00
abstract::The suprachiasmatic nucleus (SCN) of the anterior hypothalamus is implicated in the temporal organization of circadian rhythms in a variety of physiological, endocrine and behavioral processes. There is a great deal of evidence indicating that aging is characterized by a progressive deterioration of circadian timekeep...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90689-0
更新日期:1994-07-18 00:00:00
abstract::The organization and representation of conceptual knowledge in the brain remains a controversial issue in terms of both neuropsychological and imaging evidence. We report the results of a functional magnetic resonance study in which the role of the most debated dimensions (domain and feature type) was evaluated throug...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.11.070
更新日期:2008-02-15 00:00:00
abstract::Recently generated knockout mice with disrupted genes encoding endothelin (ET)-1 showed an elevation of arterial blood pressure (AP) and supplied an evidence for intrinsic ET-1 as one of the physiological regulators of systemic AP. Little is yet known, however, why deficiency of ET-1, which was originally found as a p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00848-8
更新日期:1998-10-19 00:00:00
abstract::Brain/kidney (B/K) protein is a new protein of 474 amino acids, which contains two C2 domains structurally homologous to those present in synaptotagmins. The expression of B/K protein was identified in the rat retina and B/K protein immunoreactivity was localized to a number of ganglion cells, a few amacrine cells and...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02014-x
更新日期:2000-03-31 00:00:00
abstract::The relationship between seizure propensity and the vascular anatomy of the anterior cerebral arteries, or stroke induced by unilateral ligation of the common carotid artery, was investigated utilizing well differentiated colonies of seizure-prone (SP) and non-seizure-prone (NSP) gerbils. Twenty SP and 20 NSP gerbils ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90867-8
更新日期:1982-02-25 00:00:00
abstract::The motor unit discharges in human hand muscles were recorded during voluntary isometric contraction. Bipolar wire electrodes were inserted in the right adductor pollicis muscle (AP) and first dorsal interosseous muscle (FDI) for the recordings. Motor unit activities from these muscles were investigated when subjects ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91461-7
更新日期:1986-04-30 00:00:00
abstract::The purpose of this experiment was to determine whether increased secretion of somatostatin or alterations in its molecular form contribute to the age-related decline in growth hormone secretion. Median eminences were removed from male Sprague-Dawley rats (3-4 and 21-24 months of age) and superfused with Krebs-Ringer ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90217-9
更新日期:1986-08-20 00:00:00
abstract::The impact of maternal nutrition on neurodevelopment and neonatal neuroprotection is a research topic with increasing interest. Maternal diet can also have deleterious effects on fetal brain development. Fetal exposure to alcohol is responsible for poor neonatal global development, and may increase brain vulnerability...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2020.146798
更新日期:2020-07-01 00:00:00
abstract::Pituitary adenylate-cyclase activating polypeptide (PACAP) is a neuropeptide originally isolated from the hypothalamus and located in many neuronal systems in both the central and peripheral nervous system. PACAP is also found in nerve fibers innervating the pineal gland, where it stimulates the secretion of the pinea...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)03127-5
更新日期:2003-09-12 00:00:00
abstract::Using the rapid Golgi method, the morphology of dendritic spines was quantified in the calyxes of groups of newly emerged, nurse, and forager honeybees. These groups were studied because they represented distinct stages of behavioral development and cumulative experience which, according to recent vertebrate findings,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91007-0
更新日期:1980-06-16 00:00:00
abstract::Glutamic acid decarboxylase (GAD)- and gamma-aminobutyric acid (GABA)-like immunoreactivity was examined in the retina of the 13-lined ground squirrel (Spermophilus tridecemlineatus). Labeling was observed in the inner nuclear layer (INL), inner plexiform layer (IPL) and ganglion cell layer (GCL). The immunoreactive c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91346-3
更新日期:1991-11-08 00:00:00
abstract::Neurons are distinctive in that they are generally considered to be permanently post-mitotic cells. The oncoprotein p53 is a key regulator in neuronal development, notably in cell proliferation and neuronal death. We hypothesize that p53 maintains the post-mitotic characteristic of differentiated neurons. New lines of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)04119-7
更新日期:2003-03-07 00:00:00
abstract::The enzymes catalyzing the breakdown of TRH are soluble and dependent upon active sulfhydryl groups. One of these enzymes is a pyroglutamyl aminopeptidase (EC 3.4.11.8) (apparent molecular weight 60,000 daltons) with a specificity restricted to pyroglutamyl peptide bonds. The second enzyme is a prolyl endopeptidase (a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90309-2
更新日期:1982-06-24 00:00:00
abstract::A substantial part of language understanding depends on our previous experiences, but part of it consists of the creation of new meanings. Such new meanings cannot be retrieved from memory but still have to be constructed. The goals of this article were: first, to explore the nature of new meaning creation, and second...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.09.014
更新日期:2007-12-05 00:00:00
abstract::Intrinsic versus extrinsic determinants of age-related alterations in hippocampal noradrenergic transmission were investigated using intraocular allografts in rats. Three groups of animals were examined: young hippocampal transplants in young hosts, old transplants in old hosts and young transplants in old hosts. Post...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91507-2
更新日期:1989-01-30 00:00:00
abstract::Neurofilament expression in peripheral olfactory neurons of adult rats was investigated by immunoblotting and immunohistochemistry using monoclonal antibodies specific for each of the 3 neurofilament proteins. Immunoblotting analysis of olfactory epithelium extracts demonstrated the presence of only the 200 kDa (NFH) ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90416-s
更新日期:1991-05-31 00:00:00
abstract::The effect of the protein kinase C enzyme inhibitor H-7 was examined on the brain edema formation evoked by bilateral occlusion of the common carotid arteries in Sprague-Dawley rats of CFY strain. Brain edema was assessed by measurement of water and electrolyte contents of the brain. The results showed that pretreatme...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90439-3
更新日期:1989-06-19 00:00:00
abstract::Corticosterone influences emotion and cognition via actions in a diversity of corticolimbic structures, including the amygdala. Since extracellular levels of corticosterone in brain have rarely been studied, we characterized a specific and sensitive enzymatic immunoassay for microdialysis quantification of corticoster...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2012.01.010
更新日期:2012-05-03 00:00:00
abstract::Despite insights into an increasingly significant role for delta opioid receptors in thermoregulation, it is unclear whether delta receptors located in the brain or periphery play the more critical role in body temperature regulation. Moreover, it is not entirely clear which delta receptor phenotype, delta1 or delta2,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.04.074
更新日期:2005-07-05 00:00:00
abstract::Studies have demonstrated defects of DA and 5HT neurotransmission in dietary fat induced obese animals. In the present study, we used a perfusion system to assay the release of DA and 5HT from striatal slices preloaded with [(3)H]-DA or [(3)H]-5HT. The release of both DA and 5HT from striatal slices of rats fed a high...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.06.036
更新日期:2010-08-19 00:00:00
abstract::Previous studies have clearly shown that the progressive decrease of growth hormone (GH) secretion occurring during ageing is coupled with a reduced responsiveness of pituitary GHRH receptors both in terms of GH secretion and activation of the adenylyl cyclase (AC), in the presence of increased basal values of the enz...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90340-9
更新日期:1994-04-25 00:00:00
abstract::The organization of the wing component of the dorsal column-medial lemniscal pathway, and somatosensory projections from the thalamus to the Wulst, are described for an oscine member of the major group of birds, the Passeriformes. Wing primary afferents terminate throughout the cervical spinal cord, but between the br...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00253-9
更新日期:1997-06-06 00:00:00
abstract::The properties of inward-rectifying membrane currents in immature rat olfactory cortex neurones (postnatal day (P) 10-22) were analysed using whole-cell patch-clamp recordings. In 78% of cells (40/51), injection of hyperpolarizing current pulses elicited graded electrotonic potentials showing a slowly developing sag i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)01067-1
更新日期:1998-12-14 00:00:00
abstract::Based on electrophysiological data showing that repeated cocaine administration produces persistent enhancement of D1 dopamine (DA) receptor-mediated responses in nucleus accumbens (NAc), we investigated whether changes in neurochemical properties of these receptors resulted when rats were injected with cocaine (15 mg...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90783-6
更新日期:1992-02-28 00:00:00
abstract::Monoamine uptake inhibitors block the neurotoxic effects of methamphetamine (MA) upon dopaminergic and serotonergic neurons in the rat. The neurotoxic effects of MA upon dopaminergic neurons have previously been suggested to be mediated via formation of 6-hydroxydopamine (6-OHDA) from endogenous stores of dopamine (DA...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90889-j
更新日期:1990-05-14 00:00:00
abstract::The tumor promoting compound 12-O-tetradecanoyl-phorbol-13-acetate (TPA) specifically binds to and activates protein kinase C (PKC). This enzyme is widely distributed in the brain. It plays a pivotal role in transmembrane signalling. Arachidonic acid conversion is a common cellular response to membrane perturbation. W...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90461-6
更新日期:1987-08-11 00:00:00