Abstract：
:The relationship between seizure propensity and the vascular anatomy of the anterior cerebral arteries, or stroke induced by unilateral ligation of the common carotid artery, was investigated utilizing well differentiated colonies of seizure-prone (SP) and non-seizure-prone (NSP) gerbils. Twenty SP and 20 NSP gerbils were perfused with a latex dye and the vascular patterns of the anterior cerebral arteries (ACA) were analyzed. In addition, 30 SP and 30 NSP gerbils were subjected to unilateral ligation of the common carotid artery and the number developing stroke (determined by clinical observation as well as by microscopic examination of the brain) was recorded. We found that in all animals the ACAs formed a fused-central vessel which vascularized the olfactory bulbs, as well as two lateral vessels (rostral arteries) that vascularized a previously undescribed nasal plexus. Neither the vascular pattern of the ACA, nor the frequency of occurrence of stroke following unilateral ligation was related to seizure propensity.
journal_name
Brain Resjournal_title
Brain researchauthors
Donadio MF,Kozlowski PB,Kaplan H,Wisniewski HM,Majkowski Jdoi
10.1016/0006-8993(82)90867-8subject
Has Abstractpub_date
1982-02-25 00:00:00pages
263-73issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(82)90867-8journal_volume
234pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:We have previously reported that intracerebroventricular injection of prostaglandin E2 (PGE2) induces hyperthermia possibly through EP1 receptors in the rat. In the present study, to determine the sites in the brain where PGE2 induces hyperthermia through EP1 receptors, we microinjected an EP1 receptor agonist, 17-phe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00562-3
更新日期：1997-08-29 00:00:00
abstract：:The respiratory role of GABA(A), GABA(B) and glycine receptors within the Bötzinger complex (BötC) and the pre-Bötzinger complex (preBötC) was investigated in alpha-chloralose-urethane anesthetized, vagotomized, paralysed and artificially ventilated rabbits by using bilateral microinjections (30-50 nl) of GABA and gly...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.05.032
更新日期：2010-07-16 00:00:00
abstract：:An endogenous asymmetry in striatal dopaminergic function has been identified in rats, and related to spontaneous and drug-induced circling (rotation, turning). We have developed an electronic device for measuring in humans the same kinds of rotational movements observed in rats. Our data indicate that, without being ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91074-2
更新日期：1987-05-19 00:00:00
abstract：:We used double-barreled pH-sensitive microelectrodes to study the mechanisms by which the intracellular pH is regulated in the connective glial cells of the medicinal leech. The experiments indicate that a Cl(-)- and HCO3(-)-dependent mechanism mediates some recovery from intracellular alkalosis even in the absence of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91144-4
更新日期：1994-11-28 00:00:00
abstract：:Circling training during rat striatum postnatal critical period (PN30 to 37 days) induces a life-lasting co-reduction of muscarinic acetylcholine receptors (mAChR) and dopamine D2 receptors (D2R) binding. Here, we evaluated the expression of D1R and D2R under similar experimental conditions. Trained rats showed a decr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.01.050
更新日期：2004-04-09 00:00:00
abstract：:In the electrophysiologic test of the hindlimb withdrawal reflex where the long latency component is found to be dependent on noradrenaline (NA), implants of fetal NA tissue in lesioned animals result in a recovery of NA dependent function proportional to the number of catecholamine fluorescent cells in the implants. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90396-s
更新日期：1990-02-05 00:00:00
abstract：:Horseradish peroxidase (HRP) in slow-release gel was unilaterally implanted in the transected dorsolateral funiculus (DLF) of either cervical, midthoracic, lumbar or sacral spinal cord levels of adult male rats. Cell mappings were made of all brain areas projecting through the DLF. Following cervical implants, dense l...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)91139-2
更新日期：1981-11-02 00:00:00
abstract：:Excitatory amino acid neurotoxicity and the inflammatory response are suspected as mediators of some of the pathological sequelae occurring as a result of spinal cord injury. Here we report temporal and regional increases of the NMDA receptor agonist, quinolinic acid (QUIN), in an experimental model of spinal contusio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91560-1
更新日期：1994-01-07 00:00:00
abstract：:Using a perifusion culture technique, the pattern of vasopressin release from the suprachiasmatic nucleus was studied in vitro under basal and stimulated conditions. Individual rat suprachiasmatic explants released vasopressin in a rhythmic fashion and these rhythms persisted with a circadian period for up to 4 cycles...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90952-8
更新日期：1987-10-06 00:00:00
abstract：:Steps of torque were applied to the human forearm during intentional flexion movements with peak velocities of 40-500 degrees/sec and during ballistically initiated flexion movements. The question asked was whether or not the motor ouput to both agonist and antagonist muscles is independent of sensory input data or is...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90656-x
更新日期：1978-07-07 00:00:00
abstract：:This study explores the longitudinal assessment of visual evoked potentials (VEPs) in the rabbit as a method for defining factors underlying functional and structural changes associated with optic neuritis and the inflammatory demyelinating diseases. In rabbits with experimental autoimmune encephalomyelitis (EAE) indu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90557-4
更新日期：1988-10-18 00:00:00
abstract：:Inhibitory GABAergic synaptic transmission in the mammalian hippocampus depends upon a hyperpolarized reversal potential for Cl(-) (ECl). To examine the regulation of ECl hyperpolarization we cultured hippocampal neurons for two weeks in either a low- or a high-concentration of KCl (2.6 or 18.7 mM, respectively). Neur...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.02.038
更新日期：2008-04-18 00:00:00
abstract：:Brain-derived neurotrophic factor (BDNF) is a well neurotrophic factor with neuroprotective potentials for various diseases in the central nervous system. However several previous studies demonstrated that BDNF might deteriorate symptoms for epilepsy model of animals by progression of abnormal neurogenesis. We hypothe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.10.054
更新日期：2011-01-12 00:00:00
abstract：:In order to analyze the mechanism of burst discharges intracellular recordings were made from 27 somatosensory thalamic reticular (S-TR) neurons in urethane-anesthetized rats. Burst discharges, composed of 2-7 spikes, were always superposed on a slow depolarization (SD) lasting for 40-60 ms, which appeared only when t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90539-8
更新日期：1989-03-13 00:00:00
abstract：:Application of horseradish peroxidase (HRP) to the proximal stump of the transected infraorbital (IO) nerve in the orbit was employed in normal adult rats to demonstrate the ganglionic representation of and brainstem innervation by the trigeminal (V) branch which supplies primarily the mystacial vibrissae. In the V ga...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90970-8
更新日期：1983-06-13 00:00:00
abstract：:Previous studies have reported that schizophrenia (SZ) patients showed selective reinforcement learning deficits and abnormal feedback-related event-related potential (ERP) components. However, how the brain networks and their topological properties evolve over time during transient feedback-related cognition processi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146979
更新日期：2020-11-01 00:00:00
abstract：:We have previously observed that chronic cocaine administration increases levels of adenylyl cyclase and cAMP-dependent protein kinase (PKA) in the nucleus accumbens (NAc). In the present work we directly examined the involvement of the cAMP system at the level of the NAc in cocaine-induced locomotor activity and sens...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00030-t
更新日期：1995-03-20 00:00:00
abstract：:Infusion of 1 microgram of carbachol, a potent cholinergic agonist, into the lateral septum of the urethane-anaesthetized rat systematically caused the induction of clear-cut hippocampal theta (theta). However, infusion of an equivalent amount of the drug into the hippocampus, close to the recording electrode, failed ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91551-3
更新日期：1993-12-24 00:00:00
abstract：:Membrane properties of rat magnocellular neuroendocrine cells (MNCs) were examined during intracellular recordings in vivo. Current-clamp experiments revealed sustained outward rectification positive to -55 mV and transient outward rectification of depolarizing responses elicited from negative holding potentials. Trai...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90535-4
更新日期：1991-02-01 00:00:00
abstract：:Geranylgeranylacetone (GGA), more commonly known as an antiulcer agent, reportedly induces the heat shock protein 70 (HSP70) family in the gastric mucosa, liver and heart of rats. However, it has not been reported whether HSPs, and other factors that contribute to neuroprotection, are inducible in the brain following ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)03540-6
更新日期：2003-11-21 00:00:00
abstract：:Bismuth (Bi) can produce neurotoxic effects in both humans and animals under certain dosing conditions, but little else is known about the effects of Bi in the brain. In the present study we determined the distribution of Bi in the brains of adult female Swiss-Webster mice 4, 7, 14, 21 and 28 days after a single 2500 ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00146-1
更新日期：1996-07-01 00:00:00
abstract：:Leukocyte behavior in the cerebral microvasculature following vessel occlusion has not been fully elucidated. The purpose of this study was to investigate the effects of cilostazol on leukocyte behavior (rolling and adhesion) in murine cerebral microvessels following transient bilateral carotid artery occlusion using ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.11.017
更新日期：2014-01-16 00:00:00
abstract：:The central myelin sheaths of the recessive autosomal mutant mouse, Shiverer, were investigated by electron microscopy with special reference to the pattern of myelin formation. The results obtained may be summarized as follows: (1) the major dense line of myelin lamellae generally failed to be formed, but the axons w...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90269-9
更新日期：1981-08-24 00:00:00
abstract：:An in vitro model was used to study the cytokinetics of astroglial cells derived from neonatal rat cerebellum. Confluent monolayers of astrocytes (85% astroglial as assessed by GFAP immunoreactivity) were subcultured at low cell density and after 2-3 days growth were rendered quiescent by shifting them to low serum me...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91485-0
更新日期：1988-01-26 00:00:00
abstract：:Kainic acid (KA) injections destroy hippocampal pyramidal cells, induce recurrent collateral sprouting of the hilar mossy fibers (MFs), and lead to chronic seizures. In the present study, rats were injected systemically with KA (14 mg/kg) to determine whether the subsequent occurrence of seizures was correlated with M...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90681-6
更新日期：1988-11-22 00:00:00
abstract：:The aim of the present study was to elucidate the effects of granulocyte colony-stimulating factor (G-CSF)-mediated mobilization of bone marrow-derived stem cells on the injured spinal cord. Bone marrow cells of green fluorescent protein (GFP) transgenic mice were transplanted into lethally irradiated C57BL/6 mice. Fo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.02.058
更新日期：2007-05-29 00:00:00
abstract：:The purpose of this study was to examine mechanisms involved in the coupling of neuronal activity to cerebral blood flow (CBF). CBF was measured in rat cerebellum using laser-Doppler flowmetry during stimulus-evoked neuronal activity and related to the distribution of the extracellular field potential. Local electrica...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01354-7
更新日期：1996-02-26 00:00:00
abstract：:Rarely do we encounter a single odorant in our environment. Perception of odours, therefore, usually depends on the reception and neural processing of many components. However, little is known about how and where odour mixtures are processed. Evidence is presented here that suppression of one odour by another, a commo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90419-7
更新日期：1987-11-17 00:00:00
abstract：:The response of two populations of neurones in the substantia nigra (nigro-striatal compacta neurones and reticulata neurones) to microelectrophoretically administered putative neurotransmitters and stimulation of the ipsilateral striatum has been investigated in anaesthetized rats. There were marked differences betwe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90467-4
更新日期：1981-05-18 00:00:00
abstract：:The mechanism(s) underlying age-associated diminutions in the rat striatal D2 dopamine receptor (D2-receptor) number was investigated. The levels of D2-receptor mRNA in 4-, 12- and 18-month-old rat striata were found not to change. In contrast, the levels of 110 kDa protein, labeled with a D2-receptor specific antibod...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90095-q
更新日期：1992-03-20 00:00:00
