Post-transcriptional regulation of loss of rat striatal D2 dopamine receptor during aging.

abstract：:Mounting evidence suggests that sleep loss negatively affects learning and memory processes through disruption of hippocampal function. In the present study, we examined whether sleep loss alters the generation, differentiation, and survival of new cells in the dentate gyrus. Rats were sleep restricted by keeping them...

journal_title：Brain research

authors： Roman V,Van der Borght K,Leemburg SA,Van der Zee EA,Meerlo P

更新日期：2005-12-14 00:00:00

abstract：:Defined concentrations of quinolinate (QUIN) were administered to murine cortical neurons in culture impaled for intracellular recording. In physiological recording medium containing 1 mM Mg, concentrations of QUIN up to 2 mM had minimal effect on membrane potential and input resistance; only at higher concentrations ...

journal_title：Brain research

authors： Peters S,Choi DW

更新日期：1987-09-08 00:00:00

abstract：:We previously reported the presence of Erk2 type mitogen-activated protein kinase (MAPK) and enrichment of its substrates in the post-synaptic density (PSD) fraction, and suggested a role for MAPK in the synaptic transmission and its modulation [Suzuki, T., Okumura-Noji, K., Nishida, E., ERK2-type mitogen-activated pr...

journal_title：Brain research

authors： Suzuki T,Mitake S,Murata S

更新日期：1999-09-04 00:00:00

abstract：:The recruitment of performance control was recently explained in terms of the detection of response conflict. One recent hypothesis claims that the degree of response conflict is reflected in an electroencephalographical component, the Error Negativity (Ne). Indeed, in the framework of simulations, variations of the N...

journal_title：Brain research

authors： Carbonnell L,Falkenstein M

更新日期：2006-06-20 00:00:00

abstract：:In recent years estradiol has emerged as a potential regulator of transient receptor potential vanilloid (TRPV) cationic channels in the peripheral tissues and sensory neurons, however, its analogous role in the CNS is poorly understood. TRPV channels modulate Ca2+ signalling, neurotransmission and behaviour, and expr...

journal_title：Brain research

authors： Kumar S,Singh O,Singh U,Goswami C,Singru PS

更新日期：2018-12-15 00:00:00

abstract：:Single unit extracellular recordings were obtained from cat lumbar spinal cord dorsal horn neurons activated by cutaneous inputs. The effect of electrical conditioning stimuli applied to the red nucleus (RN) was predominantly that of inhibition although in some cases excitation was seen. All the neurons that projected...

journal_title：Brain research

authors： Gray BG,Dostrovsky JO

更新日期：1984-10-08 00:00:00

abstract：:Our previous studies have shown that there is a lower cGMP concentration in the aged brain as well as an alteration in the activity of cGMP-hydrolyzing phosphodiesterases (PDEs) and nitric oxide synthase (NOS). The aim of this study was to investigate the effect of specific inhibitors of selected PDEs on object recogn...

journal_title：Brain research

authors： Domek-Łopacińska K,Strosznajder JB

更新日期：2008-06-24 00:00:00

abstract：:Poor sleep and insomnia have been recognized to be strongly correlated with the development of depression. The exploration of the basic mechanism of sleep disturbance could provide the basis for improved understanding and treatment of insomnia and prevention of depression. In this study, 31 subjects with insomnia symp...

journal_title：Brain research

authors： Liu CH,Liu CZ,Zhang J,Yuan Z,Tang LR,Tie CL,Fan J,Liu QQ

更新日期：2016-10-01 00:00:00

abstract：:Placental Opioid-Enhancing Factor (POEF) is a substance found in amniotic fluid (AF) that, when ingested, potentiates opioid-mediated, but not non-opioid-mediated, hypoalgesia. Vaginal-cervical stimulation (VCS) produces a stimulus-bound, partially opioid-mediated hypoalgesia that previous research has shown to be pot...

journal_title：Brain research

authors： Hoey RF,Hurley SW,Daniels D,Kristal MB

更新日期：2011-02-28 00:00:00

abstract：:This report deals with a comparison of total and regional cerebral blood flow with red cell velocity in the microcirculation of the ecto- and suprasylvian areas of the cerebral cortex of the cat and their response to changes in systemic blood pressure. Total and regional blood flows were measured during a steady-state...

journal_title：Brain research

authors： Chang BL,Santillan G,Bing RJ

更新日期：1984-08-06 00:00:00

abstract：:In the brain, nitric oxide (NO) has been identified as a messenger molecule and a mediator of excitatory amino acid-induced neurotoxicity. In this study, the effects of NO on serum-induced mitogenesis and cell proliferation of the cerebellar glial cells were assessed. NO-generating agent, S-nitroso-N-acetylpenicillami...

journal_title：Brain research

authors： Garg UC,Devi L,Turndorf H,Goldfrank LR,Bansinath M

更新日期：1992-10-02 00:00:00

abstract：:Lesions of the insular cortex (IC) attenuate acquisition of conditioned taste aversions (CTAs). We have suggested that this impairment is the expected consequence of a failure of IC-lesioned (ICX) rats to recognize unfamiliar taste stimuli as novel. That is, ICX rats treat novel taste stimuli as if they are familiar a...

journal_title：Brain research

authors： Roman C,Lin JY,Reilly S

更新日期：2009-03-09 00:00:00

abstract：:Fetal mouse dorsal root ganglion (DRG) neurons were maintained in primary dissociated cell culture for periods of 7 days to 3 months. Intracellular recordings from these cells revealed the presence of spontaneous subthreshold potentials in 101/177 neurons studied. When measured at the resting membrane potential, these...

journal_title：Brain research

authors： Mathers DA,Barker JL

更新日期：1984-02-13 00:00:00

abstract：:Met-enkephalin-like immunoreactivity in microdialysates from the respiratory-related nucleus tractus solitarii was determined simultaneously with ventilatory responses in seven, spontaneously breathing, developing swine under conditions of normoxia, hypoxia and recovery from hypoxia for 30 min each. Assayed levels of ...

journal_title：Brain research

authors： Yan S,Zhang C,Laferrière,Moss IR

更新日期：1995-07-31 00:00:00

abstract：:The effects of forced swimming for 30 min on extracellular 5-hydroxytryptamine (5-HT) levels were examined in five brain regions in rats using in vivo microdialysis. A single dialysis probe was implanted under surgical anesthesia into either the striatum, ventral hippocampus, frontal cortex, amygdala, or lateral septu...

journal_title：Brain research

authors： Kirby LG,Allen AR,Lucki I

更新日期：1995-06-05 00:00:00

abstract：:Biocytin is useful for intracellular filling in living slices because it is soluble, has high electrophoretic mobility and a high affinity for avidin. In fixed slices, however, membrane potential cannot be used to signify that a cell is impaled. Thus, it is necessary to inject a fluorescent molecule so that impalement...

journal_title：Brain research

authors： Liu WL,Behbehani MM,Shipley MT

更新日期：1993-04-09 00:00:00

abstract：:In barbiturate-anaesthetized spinal cats, antibody microprobes were used to examine immunoreactive substance P (irSP) release at sites within the spinal cord following cutaneous stimuli. A basal level of irSP release was detected in the region of the substantia gelatinosa of the lumbar spinal cord. No increase in this...

journal_title：Brain research

authors： Duggan AW,Hendry IA,Morton CR,Hutchison WD,Zhao ZQ

更新日期：1988-06-07 00:00:00

abstract：:A substantial projection from the retina to the dorsal raphe nucleus (DRN) has been demonstrated in the Chilean degus, a diurnal/crepuscular hystricomorph rodent. Following intraocular injection of cholera toxin subunit B (CTB), immunocytochemically labeled CTB-positive axons and terminals were observed in all major r...

journal_title：Brain research

authors： Fite KV,Janusonis S

更新日期：2001-03-23 00:00:00

abstract：:The major initiation process of intracranial aneurysms is thought to involve endothelial dysfunction due to hemodynamic stress. Angiotensin II type 1 receptor blockers and statins improve vascular endothelium function. The effects of olmesartan and pravastatin were investigated on the development of experimental aneur...

journal_title：Brain research

authors： Kimura N,Shimizu H,Eldawoody H,Nakayama T,Saito A,Tominaga T,Takahashi A

更新日期：2010-03-31 00:00:00

abstract：:Neurokinins, such as substance P (SP), modulate the reflex regulation of cardiovascular and respiratory function in the CNS, particularly in the nucleus tractus solitarius (NTS). There is considerable evidence of the action of SP in the NTS, but the precise effects have not yet been determined. Voltage-dependent Ca2+ ...

journal_title：Brain research

authors： Endoh T

更新日期：2006-09-19 00:00:00

abstract：:The mechanism of the antinociceptive effect of the tricyclic antidepressant imipramine was investigated in mice. Intrathecal (i.t.) administration of imipramine produced dose-dependent antinociception in the tail-pinch and tail-flick tests with ED50 values (95% confidence limit) of 27.5 (17.0-43.9) and 20.2 (12.6-32.2...

journal_title：Brain research

authors： Iwashita T,Shimizu T

更新日期：1992-05-22 00:00:00

abstract：:Beta-amyloid(1-42) peptide (betaAP) was injected into the right nucleus basalis magnocellularis (nbm) of rats. After a 14-day survival time, the acetylcholinesterase and choline acetyltransferase activities and the number of muscarinic receptors were found biochemically to be significantly reduced in the ipsilateral f...

journal_title：Brain research

authors： Harkany T,Lengyel Z,Soós K,Penke B,Luiten PG,Gulya K

更新日期：1995-10-09 00:00:00

abstract：:Hepatocyte growth factor (HGF/SF), is a heparin-binding polypeptide which stimulates DNA synthesis in a variety of cell types and also promotes cell migration and morphogenesis. HGF/SF mRNA has been found in a variety of tissues, including brain. In a previous study, we showed that basic fibroblast growth factor (bFGF...

journal_title：Brain research

authors： Fenton H,Finch PW,Rubin JS,Rosenberg JM,Taylor WG,Kuo-Leblanc V,Rodriguez-Wolf M,Baird A,Schipper HM,Stopa EG

更新日期：1998-01-01 00:00:00

abstract：:Although dendritic release was first proposed in the 1970s, the mechanism of release is still subject to debate. We have used in vivo microdialysis to study the acute effects of botulinum toxin A, B and tetanus toxin injected in the substantia nigra or striatum of freely moving rats. Spontaneous and evoked dopamine re...

journal_title：Brain research

authors： Bergquist F,Niazi HS,Nissbrandt H

更新日期：2002-09-20 00:00:00

abstract：:Opioid receptor subtype antagonists differentially alter food intake under deprivation (24 h), glucoprivic (2-deoxy-D-glucose, 500 mg/kg, i.p.) or palatable (10% sucrose) conditions with mu (beta-funaltrexamine) and kappa (nor-binaltorphamine), but not delta1 ([D-Ala2,Leu5,Cys6]enkephalin) opioid antagonists reducing ...

journal_title：Brain research

authors： Ragnauth A,Ruegg H,Bodnar RJ

更新日期：1997-08-29 00:00:00

abstract：:To test the hypothesis that there is a functional modulation of conventional EEG bands associated with preparatory attention, putative changes in the spontaneous brain rhythms and their associated cerebral sources were addressed. The goals of the present report were, first, to find the brain areas with maximal rhythmi...

journal_title：Brain research

authors： Gómez CM,Marco-Pallarés J,Grau C

更新日期：2006-08-30 00:00:00

abstract：:The density of specific prostaglandin E2 (PGE2) binding sites was quantitatively mapped in the rat brain using in vitro autoradiography. The anterior wall of the third ventricle and the nucleus solitary tract were found to have a very high density of binding sites (greater than 15 fmol/mg tissue). Two thalamic nuclei ...

journal_title：Brain research

authors： Matsumura K,Watanabe Y,Imai-Matsumura K,Connolly M,Koyama Y,Onoe H,Watanabe Y

更新日期：1992-05-29 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) is a major neural signal for hypothalamic control of gonadotropin secretion which in turn influences gonadal steroid synthesis. Progesterone (P) is known to affect release and content of GnRH. The action mechanism of P on GnRH mRNA level remains, however, to be resolved. Here we r...

journal_title：Brain research

authors： Cho BN,Seong JY,Cho H,Kim K

更新日期：1994-07-25 00:00:00

abstract：:Astrogliogenesis in the human fetal cerebellum was examined in 46 cerebella obtained from hysterotomy specimens ranging between 9 and 20 weeks of ovulation age. By correlating the results obtained by rapid Golgi and Golgi-Cox methods, the indirect immunofluorescence technique for glial fibrillary acidic protein, and e...

journal_title：Brain research

authors： Choi BH,Lapham LW

更新日期：1980-05-26 00:00:00

abstract：:Cingulate cortex (CC) unit responses to hippocampal volleys and afterdischarges were studied in 4 awake unsedated squirrel monkeys using extracellular microelectrodes. Stimuli were delivered via bipolar electrodes chronically implanted bilaterally in anterior and posterior hippocampus. A total of 412 units in 21 track...

journal_title：Brain research

authors： Dagi TF,Poletti CE

更新日期：1983-01-24 00:00:00