Abstract：
:Cingulate cortex (CC) unit responses to hippocampal volleys and afterdischarges were studied in 4 awake unsedated squirrel monkeys using extracellular microelectrodes. Stimuli were delivered via bipolar electrodes chronically implanted bilaterally in anterior and posterior hippocampus. A total of 412 units in 21 tracks were studied and tested to single and multiple shock stimulation. Spontaneous firing rates were approximately equally distributed among slow (0.25 spikes/s), medium (2.5-10), and fast (10-25). Only 2% of cingulate units (9/412) responded orthodromically to hippocampal stimulation: 5 with initial excitation; 4 with initial inhibition. Eight responses had initial latencies from 100-200 ms; one unit a latency of 25 ms. Three units displayed periodic, almost cyclical, excitation. All unit response thresholds were 1 shock, 0.25 mA or less. Hippocampal afterdischarge activity influenced the firing pattern of 17 units: 16 showed intraictal excitation and 1 inhibition. In comparison with the preceding studies in the same model these results indicate that the influence of hippocampal stimulation on cingulate cortex is not nearly as prominent as either the fornix or non-fornix hippocampal influence on hypothalamic, preoptic, and basal forebrain structures. It is proposed that the cingulate cortex is not a prominent link in the Papez circuit.
journal_name
Brain Resjournal_title
Brain researchauthors
Dagi TF,Poletti CEdoi
10.1016/0006-8993(83)91253-2subject
Has Abstractpub_date
1983-01-24 00:00:00pages
229-36issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(83)91253-2journal_volume
259pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Sleep-suppressive activity of prostaglandin synthesis inhibitors, diclofenac sodium (DF) and indomethacin (IM), was examined in unrestrained male rats. An intraperitoneal injection of 5 mg/kg IM, or an oral administration of 5 mg/kg DF and 10 mg/kg IM at an early phase of the light period transiently decreased slow wa...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90173-4
更新日期：1988-06-21 00:00:00
abstract：:High cell density, with attendant aggregation, selectively increases expression of substance P (SP) and choline acetyltransferase (ChAT) in virtually pure neonatal sympathetic neuronal cultures. To investigate the specific role of cell contact in selective transmitter expression, SP content and ChAT activity were exam...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(86)80202-5
更新日期：1986-12-01 00:00:00
abstract：:Motor-related regions of parietal and prefrontal cortices have been shown to selectively activate when observers passively view objects that afford manual grasping. Yet, it remains unknown whether these cortical responses depend on prior motor-related experience with the object being observed. To address this question...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.04.059
更新日期：2006-06-30 00:00:00
abstract：:Bombesin (BN)- and substance P (SP)-containing neurons are found in the dorsal root ganglia, and project to the dorsal horn of the spinal cord. The present study was undertaken to determine if chronic deafferentation of the cat spinal cord would affect BN or SP receptors in the spinal cord. Ten and 30 days after a uni...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90744-9
更新日期：1985-09-23 00:00:00
abstract：:Previous studies have shown that preganglionic nerve stimulation in vitro increases acutely the activity of tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine biosynthesis, in sympathetic neuronal cell bodies in the rat superior cervical ganglion (SCG). In the present study, we have examined whether ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90506-7
更新日期：1990-07-30 00:00:00
abstract：:Data are presented which show a different pattern of dopamine and noradrenaline utilization in terminal regions of the A9 and A10 dopaminergic systems and in terminal regions of the dorsal noradrenergic bundle after electrical stimulation of the ventral tegmental area and an adjacent area. At the sites of the electrod...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90505-x
更新日期：1983-06-06 00:00:00
abstract：:Although an auditory area has been found over the exposed area of lobules VI-VIII in the posterior cerebellar vermis of the cat, there has been little information on its buried portion. This point should be of some concern, since very little of the brain tissue in lobules VI-VIII of the cerebellar cortex is exposed. W...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90825-g
更新日期：1991-07-12 00:00:00
abstract：:The present study sought to determine if axonal connectivity is established between 6-month-old neostriatal transplants and the host substantia nigra. Cell suspensions of fetal neostriatum were transplanted into the adult rat neostriatum lesioned previously by kainic acid. Horseradish peroxidase injections into the ip...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91256-0
更新日期：1989-01-09 00:00:00
abstract：:The effects of a 5-day ganglioside (GM1) treatment (30 mg/kg) on body weight and water intake subsequent to medial septal lesions were evaluated for 44 consecutive days. In addition, activity, rearing, and repetitive motor acts were measured on postsurgery days 5, 10, 40, and 60. The rate of increase in the body weigh...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90235-7
更新日期：1989-08-28 00:00:00
abstract：:Quantal analysis of transmitter release is useful in examining presynaptic mechanisms involved in synaptic transmission. However, in central neurons, the presence of multiple synapses makes it difficult to use the traditional quantal analysis, developed for the neuromuscular transmission. We developed a method to mini...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.02.056
更新日期：2008-05-01 00:00:00
abstract：:It has been hypothesized on the basis of animal models of epilepsy that abnormal neural activity in epilepsy may be related to reorganized neural circuits that facilitate epileptogenesis. Little evidence of this was available for human epilepsy. This paper provides the first evidence of such reorganization of a hippoc...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90234-5
更新日期：1989-08-28 00:00:00
abstract：:Recent research suggests that attributing human movement to ambiguous and static Rorschach stimuli (M responses) is associated with EEG mu suppression, and that disrupting the left inferior gyrus (LIFG; a putative area implicated in mirroring activity) decreases the tendency to see human movement when exposed to the R...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2017.12.007
更新日期：2018-02-01 00:00:00
abstract：:Intracellular free calcium concentration ([Ca2+]i) was measured in cultured explants of myenteric plexus neurones by using the fluorescent calcium indicator Indol in combination with patch-clamp techniques. The basal [Ca2+]i was 94 nM and spontaneous oscillations in the internal free calcium concentration were recorde...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90065-u
更新日期：1993-10-08 00:00:00
abstract：:Excitatory actions of acromelic acid were investigated in the isolated newborn rat spinal cord. Test compounds were added to the perfusing fluid and the responses were recorded from the ventral root extracellularly. Acromelic acid caused a depolarizing response in a dose-dependent manner and the depolarizing activity ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90456-8
更新日期：1988-12-06 00:00:00
abstract：:N2O antinociception was assessed in eight inbred and two outbred mouse strains. Results indicated the following order of responsiveness among the 10 strains: A/J (most sensitive), C57BL/6ByJ, C57BL/6J, BALB/cByJ, C3H/HeJ, Swiss-Webster, CXBK/ByJ, ICR, CBA/J and DBA/2J (least sensitive). These results demonstrate signi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91017-m
更新日期：1993-06-18 00:00:00
abstract：:Primary gaze fixation in healthy individuals is frequently interrupted by microsaccades and saccadic intrusions (SI). The neural systems responsible for the control of attention and eye movements are believed to overlap and in line with this, the behaviour of microsaccades appears to be affected by exogenous and endog...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.01.047
更新日期：2007-04-13 00:00:00
abstract：:We have previously described a rodent model of brief (30 min) middle cerebral artery occlusion followed by reperfusion, in which infarction develops gradually, reaching completion more than 3 days after ischemia, accompanied by morphological, biochemical, and pharmacological evidence of apoptosis. In the present study...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02822-0
更新日期：2001-11-02 00:00:00
abstract：:Prominent cellular responses to axonal interruption include enhanced synthesis of RNA and protein in the neuronal perikaryon, and proliferation of reactive Schwann cells. Since morphine has been shown to significantly depress cellular metabolism, we examined its effect on these and other reparative responses underlyin...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(79)91010-2
更新日期：1979-10-19 00:00:00
abstract：:Erythropoietin (EPO) provides neuroprotection and neurorestoration after traumatic brain injury (TBI). The EPO doses used for treatment of TBI significantly increase hematocrit, which may affect the efficacy of EPO therapy for TBI. The aim of this study was to investigate whether normalization of hematocrit would affe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.07.077
更新日期：2009-10-19 00:00:00
abstract：:Arg-vasopressin (AVP) containing neurons are one of the output paths from the suprachiasmatic nucleus (SCN), the center of the biological clock. AVP mRNA transcription is controlled by a negative feedback loop of clock genes. Circadian rhythm of melatonin release from the pineal gland is regulated by the SCN via the p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.04.052
更新日期：2004-07-09 00:00:00
abstract：:Loss of dopaminergic neurons from the pars compacta of the substantia nigra is the pathological hallmark of Parkinson's disease (PD) and results in a partial deafferentation to the striatum. Since deafferentation is known to induce transynaptic atrophy of postsynaptic cells, we examined by Golgi impregnation the morph...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90124-2
更新日期：1988-07-05 00:00:00
abstract：:The influence of the cortico-geniculate pathway on identified X and Y lateral geniculate cells was studied by reversibly cooling visual cortical areas 17 and 18. The majority (86.5%) of cells changed their response to visual stimulation when cortex was inactivated, and both X- and Y-cells were modulated by the cortica...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90568-0
更新日期：1981-03-16 00:00:00
abstract：:The role of central delta-opioid receptors in the mediation of opioid reinforcement and endogenous reward processes was examined using a non-biased place-preference conditioning procedure. Intracerebroventricular (i.c.v.) administration of the selective delta-receptor agonist, [D-Pen2, D-Pen5]-enkephalin (DPDPE, 10.0-...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91667-2
更新日期：1987-12-15 00:00:00
abstract：:Measurements of extracellular Ca2+ and K+ activities [( Ca2+]o, [K+]o) in the superfused cat carotid body in vitro with triple-barrelled ion-selective electrodes have shown that hypoxia induced a decrease in [Ca2+]o of 0.035 +/- 0.17 mM (mean +/- S.D.; n = 17) and a biphasic change in [K+]o which consisted of an incre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91186-4
更新日期：1989-03-20 00:00:00
abstract：:The distributions and inductions of Cu/Zn superoxide dismutase (SOD), neuronal and endothelial nitric oxide (NO) synthase (nNOS and eNOS), and nitrotyrosine (NT) were immunohistochemically examined in rabbit spinal cords after 5 and 15 min of transient ischemia. The neurons in the anterior horns (AH) were selectively ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00490-8
更新日期：1996-09-02 00:00:00
abstract：:Developmental delay, cognitive impairment, and refractory epilepsy are the most frequent consequences found in patients suffering from malformations of cortical development (MCD). However, therapeutic options for these psychiatric and neurological comorbidities are currently limited. The development of white matter un...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.07.012
更新日期：2015-10-05 00:00:00
abstract：:An immunoneutralization technique with specific antibodies was used to explore the role of endogenous neuropeptide Y (NPY) in the adrenocorticotropic hormone (ACTH) release after hypoglycemic stress in the dog. Dogs received injections of rabbit antihuman NPY gamma-globulin (anti-NPY) or normal gamma-globulin (NGG) in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91369-r
更新日期：1990-03-05 00:00:00
abstract：:We carried out ligand binding experiments on membranes from rat brain cortical grey matter using radioiodinated beta/A4 8-17, with non-specific binding determined by the addition of 10 microM unlabelled peptide. Specific, reversible binding amounted to 60-75% of total binding and showed a clear dependence on time, tem...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90905-b
更新日期：1991-06-14 00:00:00
abstract：:Two distinct patterns of terminal labeling were seen after injections of [3H]amino acids into the second somatosensory area (S2) and the retroinsular area (Ri). The first pattern, seen both in S2 after an injection in Ri and in the granular or dysgranular insular fields after an injection in S2, is characterized by he...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)91103-4
更新日期：1983-08-22 00:00:00
abstract：:Reports suggested that the predominant site of action for the antihypertensive effects of clonidine is the rostral ventrolateral medulla (RVL), the presumed tonic vasomotor center. This study examined whether clonidine directly interacts with nerve terminal alpha 2-adrenergic receptors in the RVL to inhibit the releas...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90355-f
更新日期：1990-12-24 00:00:00
