Abstract：
:The present study sought to determine if axonal connectivity is established between 6-month-old neostriatal transplants and the host substantia nigra. Cell suspensions of fetal neostriatum were transplanted into the adult rat neostriatum lesioned previously by kainic acid. Horseradish peroxidase injections into the ipsilateral ventral midbrain labelled the lesion site and the intact neostriatum extensively, but no appreciable anterograde or retrograde label was found within the graft. These results demonstrate a paucity of connectivity between neostriatal grafts and the host brain at a time when other investigators have described transplant-mediated recovery of function.
journal_name
Brain Resjournal_title
Brain researchauthors
McAllister JP 2nd,Cober SR,Schaible ER,Walker PDdoi
10.1016/0006-8993(89)91256-0subject
Has Abstractpub_date
1989-01-09 00:00:00pages
345-50issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(89)91256-0journal_volume
476pub_type
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