Caffeine-diazepam interaction and local cerebral glucose utilization in the conscious rat.

abstract：:Wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) was used to study transneuronal transport in the developing rat visual pathways. Intraocular injections of WGA-HRP were made in neonatal albino rat pups at different ages from the day of birth, postnatal day 0 (P0), to one month of age. Transneuronal...

journal_title：Brain research

authors： Itaya SK

更新日期：1988-01-01 00:00:00

abstract：:These experiments examined the effects of intra-amygdala injections of NMDA receptor antagonists on the acquisition and retention of inhibitory avoidance. In Expt. I, rats received bilateral intra-amygdala injections of the NMDA antagonists D,L-AP5 (1-10 micrograms), D-AP5 (0.03-1 micrograms), CPP (0.125 or 0.375 micr...

journal_title：Brain research

authors： Kim M,McGaugh JL

更新日期：1992-07-10 00:00:00

abstract：:Picture-word interference is a widely employed paradigm to investigate lexical access in word production: Speakers name pictures while trying to ignore superimposed distractor words. The distractor can be congruent to the picture (pictured cat, word cat), categorically related (pictured cat, word dog), or unrelated (p...

journal_title：Brain research

authors： Piai V,Roelofs A,van der Meij R

更新日期：2012-04-23 00:00:00

abstract：:Magnetoencephalography (MEG) was used to investigate the response to speech sounds that differ in onset dynamics, parameterized as words that have initial stop consonants (e.g., /b/, /t/) or do not (e.g., /m/, /f/). Latency and amplitude of the M100 auditory evoked neuromagnetic field, recorded over right and left aud...

journal_title：Brain research

authors： Gage N,Poeppel D,Roberts TP,Hickok G

更新日期：1998-12-14 00:00:00

abstract：:A growth hormone (GH) injection is able to induce the phosphorylated form of the signal transducer and activator of transcription 5 (pSTAT5) in a large number of cells throughout the mouse brain. The present study had the objective to map the distribution of GH-responsive cells in the brain of rats that received an in...

journal_title：Brain research

authors： Wasinski F,Klein MO,Bittencourt JC,Metzger M,Donato J Jr

更新日期：2021-01-15 00:00:00

abstract：:During aging, estrogen production and circulating levels of estrogen are markedly decreased in females. Although several differences exist in the process of reproductive aging between women and female rats, the results of many studies suggest that the female rat, especially the middle-aged or aged ovariectomized femal...

journal_title：Brain research

authors： Yamaguchi N,Yuri K

更新日期：2014-01-16 00:00:00

abstract：:Breakdown products (BDPs) resulting from the partial proteolysis of spectrin were examined in hippocampal slices after periods of hypoxia lasting for 5 or 10 min. The concentration of a approximately 155 kDa BDP increased nearly twofold after 5 min of hypoxia; further increases were not seen with 10 min episodes or 10...

journal_title：Brain research

authors： Arai A,Vanderklish P,Kessler M,Lee K,Lynch G

更新日期：1991-08-02 00:00:00

abstract：:Intraocular injections of several different retrograde tracers were made in albino rats. Retrogradely filled neurons were observed in two locations: the medial pretectal area and the contralateral periaqueductal grey matter, indicating that the pretectum and the mesencephalon are sources of centrifugal innervation to ...

journal_title：Brain research

authors： Itaya SK,Itaya PW

更新日期：1985-02-11 00:00:00

abstract：:The effects of intracerebroventricular (i.c.v.) infusion of arginine vasopressin (AVP) on intracranial pressure (ICP), blood pressure (BP) and plasma AVP were investigated in conscious goats. The animals were implanted with ventricular (V) and cisternal (C) cannulae under halothane anaesthesia and allowed to recover p...

journal_title：Brain research

authors： Seckl JR,Lightman SL

更新日期：1987-10-13 00:00:00

abstract：:The possible involvement of the nitric oxide (NO)-cyclic GMP (cGMP)-protein kinase G (PKG) pathway on bovine lactoferrin (BLF)-induced spinal antihyperalgesic activity was elucidated in sciatic nerve injured rats. Intrathecal BLF reduced thermal hyperalgesia in a dose-dependent manner. Pretreatment with NG-L-nitro-arg...

journal_title：Brain research

authors： Wang J,Zhang LC,Lv YW,Ji Y,Yan XJ,Xue JP

更新日期：2008-05-13 00:00:00

abstract：:Regulation of the intracellular calcium concentration ([Ca(2+)](i)) is of critical importance for synaptic function. Therefore, neurons buffer [Ca(2+)](i) using intracellular Ca(2+)-binding proteins (CaBPs). Previous evidence suggests that Calbindin-D(28K) (CB), an abundantly expressed endogenous fast CaBP, plays an i...

journal_title：Brain research

authors： Westerink RH,Beekwilder JP,Wadman WJ

更新日期：2012-04-23 00:00:00

abstract：:The effects of streptozotocin-induced diabetes mellitus on the activity of discrete regions of the brain were studied with histochemical localization and photodensitometric quantification of the metabolic enzyme, hexokinase. Two weeks after a single injection of streptozotocin (65 mg/kg, i.p.), plasma glucose and osmo...

journal_title：Brain research

authors： Krukoff TL,Patel KP

更新日期：1990-07-02 00:00:00

abstract：:Traumatic brain injury (TBI) causes impairments of both motor and spatial memory performances. Research is only beginning to reveal the biochemical mechanism(s) underlying these deficits. It has been postulated that reactive oxygen species such as the superoxide and hydroxyl radicals, as well as the peroxynitrite anio...

journal_title：Brain research

authors： Long DA,Ghosh K,Moore AN,Dixon CE,Dash PK

更新日期：1996-04-22 00:00:00

abstract：:An endogenous asymmetry in striatal dopaminergic function has been identified in rats, and related to spontaneous and drug-induced circling (rotation, turning). We have developed an electronic device for measuring in humans the same kinds of rotational movements observed in rats. Our data indicate that, without being ...

journal_title：Brain research

authors： Bracha HS,Seitz DJ,Otemaa J,Glick SD

更新日期：1987-05-19 00:00:00

abstract：:Brevetoxins (PbTx) are potent allosteric enhancers of voltage-gated sodium channel (VGSC) function and are associated with periodic "red tide" blooms. These neurotoxins produce neuronal injury and death in cerebellar granule cells (CGC) following acute exposure. In murine neocortical neurons, brevetoxin induces Ca(2+)...

journal_title：Brain research

authors： Dravid SM,Baden DG,Murray TF

更新日期：2005-01-07 00:00:00

abstract：:The distribution of AMPA-type glutamate receptor (GluR) subunits was studied in the Edinger-Westphal nucleus (EW) of chicks and pigeons. GluR1, GluR2, GluR3 and GluR4 subunits appeared to be present in EW neurons of both species, but interspecific differences were observed in the abundance of the different types of su...

journal_title：Brain research

authors： Toledo CA,Britto LR,Pires RS,Veenman CL,Reiner A

更新日期：2002-08-23 00:00:00

abstract：:Following injection of the acylating reagent N-succinimidyl [3H]propionate into the optic nerve of goldfish, labeled protein appeared in the ipsilateral retina and contralateral tectum in a time-dependent manner. Autoradiography indicated the presence of the labeled material in the neuroplasm of the retinal ganglion c...

journal_title：Brain research

authors： Williams LR,Agranoff BW

更新日期：1983-01-24 00:00:00

abstract：:In freely-moving rats treated with a combination of reserpine (10 mg/kg, i.p.) and scopolamine (5 mg/kg, i.p.), neocortical low voltage fast activity (LVFA) associated with continuous multiunit activity (MUA) was abolished and replaced by 2-6 Hz large irregular slow activity (LISA) above 1.5 mV associated with a burst...

journal_title：Brain research

authors： Dringenberg HC,Vanderwolf CH

更新日期：1996-07-29 00:00:00

abstract：:Nitric oxide (NO) is a neuronal messenger that it is thought to be involved in the nociceptive transmission modulation. The activity of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) was shown to be identical to NOS activity in the brain. Since the periaqueductal gray matter (PAG) plays an important ...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1998-05-18 00:00:00

abstract：:During early postnatal development in reeler mutant mice, lectin binding delineates prospective abnormal barrels as they will appear in the adult mutant somatosensory cortex. Glial fibers also may be more condensed within fascicles in developing reeler barrels. These fibers also appear to be misaligned, coursing predo...

journal_title：Brain research

authors： O'Brien TF,Steindler DA,Cooper NG

更新日期：1987-04-01 00:00:00

abstract：:The putative neurotransmitter substance P was localized in the embryonic and neonatal mouse trigeminal nerve by indirect immunofluorescence. Central terminals in the nucleus caudalis gave a positive substance P-like immunofluorescence (SPLI) reaction of E13-E14. SPLI subsequently appeared in the peripheral mucous and ...

journal_title：Brain research

authors： Mohamed SS,Atkinson ME

更新日期：1982-07-01 00:00:00

abstract：:Extracellular amino acids were followed in the hippocampus during sustained seizures induced by systemic administration of kainic acid (KA) or bicuculline (BC). KA epilepsy was associated with marked increases in phosphoethanolamine (PEA) and taurine. Alanine and ethanolamine were moderately raised while other amino a...

journal_title：Brain research

authors： Lehmann A,Hagberg H,Jacobson I,Hamberger A

更新日期：1985-12-16 00:00:00

abstract：:Catecholamine-containing fibers have been examined in the cerebella of normal and hypocerebellar mutant mice using Falck-Hillarp and glyoxylic acid histofluorescence techniques. The amounts of norepinephrine and dopamine were also determined chemically in the same mutants. Green fluorescent fibers in cerebella of norm...

journal_title：Brain research

authors： Landis SC,Shoemaker WJ,Schlumpf M,Bloom FE

更新日期：1975-08-08 00:00:00

abstract：:A systematic clinical neuroscience protocol is described for the use to examine the trigemino-cardiac reflex (TCR) response in humans. Target neurosurgical conditions are operations that require manipulations around the peripheral and central part of the trigeminal nerve and its branches, e.g. the cerebellopontine ang...

journal_title：Brain research

authors： Schaller BJ,Weigel D,Filis A,Buchfelder M

更新日期：2007-05-29 00:00:00

abstract：:Reward deficit, expressed as anhedonia, is one of the major symptoms associated with neuropsychiatric disorders, but the underlying maladaptations have not been understood. Herein, we test the hypothesis that the neuropeptide cocaine- and amphetamine-regulated transcript (CART) may participate in the process. The stud...

journal_title：Brain research

authors： Somalwar AR,Choudhary AG,Balasubramanian N,Sakharkar AJ,Subhedar NK,Kokare DM

更新日期：2020-02-01 00:00:00

abstract：:MicroRNAs (miRNAs) are short, non-coding RNAs that negatively regulate target gene expression, and play an important role in cerebral ischemic injury. MiR-146a has been reported to be highly related to cell invasion, metastasis, immunity, inflammation and apoptosis. Previous studies have indicated that miR-146a can ei...

journal_title：Brain research

authors： Zhou X,Su S,Li S,Pang X,Chen C,Li J,Liu J

更新日期：2016-10-01 00:00:00

abstract：:Previous studies have shown that microinjection of morphine into the prefrontal ventrolateral orbital cortex (VLO) produces antinociception. The current study examined whether gamma-aminobutyric acid (GABA) containing neurons in the VLO were involved in this antinociception. Under light anesthesia, the GABA(A) recepto...

journal_title：Brain research

authors： Qu CL,Tang JS,Jia H

更新日期：2006-02-16 00:00:00

abstract：:Intracellular recordings and labelings with horseradish peroxidase (HRP) of expiratory (E) neurons were performed in decerebrate, paralyzed, and ventilated rats. A total of 37 neurons were recorded, from which 4 cells and 1 axon were labeled. They were located in two regions of the ventrolateral medulla. One was in th...

journal_title：Brain research

authors： Zheng Y,Barillot JC,Bianchi AL

更新日期：1992-04-03 00:00:00

abstract：:Stroke-prone spontaneously hypertensive rats (SHRSP) are a well-characterized, genetic model for stroke. We showed earlier that the structure and function of the tight junctions in SHRSP blood-brain barrier endothelial cells is disturbed prior to stroke. To investigate the molecular events leading to endothelial dysfu...

journal_title：Brain research

authors： Kirsch T,Wellner M,Luft FC,Haller H,Lippoldt A

更新日期：2001-08-10 00:00:00

abstract：:Kernicterus is a bilirubin-induced encephalopathy in newborn. Its spectrum ranges from subtle extrapyramidal to acute encephalopathy and chronic posticteric sequelae. Current treatment of this serious problem is far from optimal. Taurine has been documented to have protective effects on neuronal cells against ischemia...

journal_title：Brain research

authors： Zhang B,Yang X,Gao X

更新日期：2010-03-12 00:00:00