Abstract：
:During early postnatal development in reeler mutant mice, lectin binding delineates prospective abnormal barrels as they will appear in the adult mutant somatosensory cortex. Glial fibers also may be more condensed within fascicles in developing reeler barrels. These fibers also appear to be misaligned, coursing predominantly in the tangential plane within the abnormal reeler barrel sides as opposed to having a radial orientation as seen in normal mouse barrels. The thalamic barreloid complex, however, reveals a disposition of glycoconjugates that is completely normal in reeler. Thus, there are anomalies in glia and associated glycoconjugates during mainly cortical development in the reeler mutant mouse that might be related to the primary action of the abnormal gene.
journal_name
Brain Resjournal_title
Brain researchauthors
O'Brien TF,Steindler DA,Cooper NGdoi
10.1016/0165-3806(87)90112-xsubject
Has Abstractpub_date
1987-04-01 00:00:00pages
309-17issue
2eissn
0006-8993issn
1872-6240journal_volume
429pub_type
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