Enhanced neural response by adult rats to odors experienced early in life.

Abstract:

:The enhanced olfactory bulb neural response to familiar odors by young rats persists into adulthood. Ninety-day-old rats who had received neonatal odor exposure had an enhanced uptake of [14C]2-deoxyglucose (2-DG) when exposed to the familiar odor. The odor-familiar rats did not have an increased respiration rate during the 2-DG test. A long-lasting change in neuronal response is consistent with the observation of behavioral effects of early odor experience persisting into adulthood.

journal_name

Brain Res

journal_title

Brain research

authors

Coopersmith R,Leon M

doi

10.1016/0006-8993(86)90384-7

subject

Has Abstract

pub_date

1986-04-23 00:00:00

pages

400-3

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(86)90384-7

journal_volume

371

pub_type

杂志文章
  • Glutamate induces the expression and release of tumor necrosis factor-alpha in cultured hypothalamic cells.

    abstract::Tumor necrosis factor-alpha (TNFalpha) affects several CNS functions such as regulation of sleep, body temperature, and feeding during pathology. There is also evidence for TNFalpha involvement in physiological sleep regulation, e.g., TNFalpha induces sleep and brain levels of TNFalpha increase during prolonged wakefu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.06.044

    authors: De A,Krueger JM,Simasko SM

    更新日期:2005-08-16 00:00:00

  • Early changes in protein synthesis following spinal cord hemisection in the Cebus monkey (Cebus apella).

    abstract::The short term effects of spinal cord hemisection on protein synthesis in the Cebus monkey were studied by measuring the uptake of [3H]lysine into the trichloroacetic acid (TCA) precipitable and non-precipitable fractions of spinal cord. Animals were sacrificed 3, 6, or 13 days after hemisection. Two normal animals an...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(76)91046-5

    authors: Wells MR,Bernstein JJ

    更新日期:1976-07-23 00:00:00

  • The effects of N-methyl-D-aspartate receptor blockade with MK-801 upon the relationship between cerebral blood flow and glucose utilisation.

    abstract::The local cerebral circulatory and metabolic effects of MK-801, a selective non-competitive N-methyl-D-aspartate receptor antagonist have been examined in conscious rats with quantitative autoradiographic techniques using [14C]iodoantipyrine and [14C]2-deoxyglucose as tracers. Local cerebral blood flow (CBF) and local...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90172-8

    authors: Nehls DG,Park CK,MacCormack AG,McCulloch J

    更新日期:1990-03-19 00:00:00

  • Afferent cortical connections and architectonics of the superior temporal sulcus and surrounding cortex in the rhesus monkey.

    abstract::A cyto- and myeloarchitectonic parcellation of the superior temporal sulcus and surrounding cortex in the rhesus monkey has been correlated with the pattern of afferent cortical connections from ipsilateral temporal, parietal and occipital lobes, studied by both silver impregnation and autoradiographic techniques. The...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(78)90584-x

    authors: Seltzer B,Pandya DN

    更新日期:1978-06-23 00:00:00

  • Regulation of glutamate receptors: possible role of phosphatidylserine.

    abstract::The polar head group of the phospholipid phosphatidylserine is similar in structure to the glutamate analogue 2-amino-4-phosphonobutyric acid (APB), an antagonist of excitatory transmission in the brain. When tested in ligand binding assays phosphatidylserine and its polar head group components O-phosphoserine and L-a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90328-6

    authors: Foster AC,Fagg GE,Harris EW,Cotman CW

    更新日期:1982-06-24 00:00:00

  • Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-κB pathway and the NLRP3 inflammasome may be involved in the mechanism.

    abstract::Early brain injury (EBI) plays a pivotal role in the prognosis of patients with subarachnoid haemorrhage (SAH). Dexmedetomidine (DEX), a highly selective α2 receptor agonist, is reported to exert multiple protective effects in many neurological diseases. This study was designed to investigate whether DEX had neuroprot...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2018.05.040

    authors: Yin D,Zhou S,Xu X,Gao W,Li F,Ma Y,Sun D,Wu Y,Guo Q,Liu H,Han L,Wang Z,Wang Y,Zhang J

    更新日期:2018-11-01 00:00:00

  • Hydrogen peroxide as a source of molecular oxygen for in vitro mammalian CNS preparations.

    abstract::Using an isolated neonatal rat spinal cord preparation, we have studied the ability of hydrogen peroxide to act as a source of oxygen for mammalian central nervous system (CNS) maintained in vitro. We report here that hydrogen peroxide, in low concentrations (0.001-0.004%), can effectively provide the only source, or ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90280-9

    authors: Walton K,Fulton B

    更新日期:1983-11-14 00:00:00

  • Late-phase recovery in the cochlear lateral wall following severe degeneration by acute energy failure.

    abstract::We previously reported a model of acute cochlear energy failure using a mitochondrial toxin, 3-nitropropionic acid (3-NP), to study mechanisms of inner ear disorders such as inner ear ischemia. In this model, the main cause of hearing loss is apoptosis of fibrocytes in the cochlear lateral wall. Here, we analyzed the ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.08.062

    authors: Mizutari K,Nakagawa S,Mutai H,Fujii M,Ogawa K,Matsunaga T

    更新日期:2011-10-24 00:00:00

  • The vestibulo ocular reflex (VOR) in otoconia deficient head tilt (het) mutant mice versus wild type C57BL/6 mice.

    abstract::The horizontal and vertical vestibulo ocular reflex (VOR) of head tilted (het) mutant mice was compared to C57BL/6 controls. Eye movements were recorded in darkness using a temporarily attached search coil. Contributions of semicircular canal versus otolith organ signals were investigated by providing a canal only (ve...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)02505-8

    authors: Harrod CG,Baker JF

    更新日期:2003-05-16 00:00:00

  • Electrical activity of neurosecretory axons from the brain of Rhodnius prolixus: relation of changes in the pattern of activity to endocrine events during the moulting cycle.

    abstract::Ongoing electrical activity was recorded from the axons of neurosecretory cells from the brain of 5th instar Rhodnius prolixus throughout the moulting cycle. Dramatic changes in both the frequency and pattern of electrical activity occur at specific times during the cycle, enabling the timing of release of neurohormon...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90314-5

    authors: Orchard I,Steel CG

    更新日期:1980-06-02 00:00:00

  • Morphology of peptide-containing neurons in the rat basolateral amygdaloid nucleus.

    abstract::The peroxidase-antiperoxidase (PAP) immunohistochemical technique was used to identify neurons in the basolateral amygdaloid nucleus (BL) that contain vasoactive intestinal polypeptide (VIP), somatostatin (SOM) or cholecystokinin (CCK). Examination of immunostained neurons demonstrated that most, if not all, of these ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90266-5

    authors: McDonald AJ

    更新日期:1985-07-08 00:00:00

  • A test of the spine resistance hypothesis for LTP expression.

    abstract::Long-term potentiation (LTP) consists of an enhanced response to released transmitter by the quisqualate/AMPA subclass of glutamate receptors with little change in the slower currents generated by the NMDA receptor subclass. Recent computer simulations suggest that a decrease in the resistance of dendritic spines woul...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90454-4

    authors: Larson J,Lynch G

    更新日期:1991-01-11 00:00:00

  • Simulation of cerebral hemodynamics for preoperative risk assessment.

    abstract:BACKGROUND:An important part of the medical treatment of many cerebrovascular diseases is the occlusion of brain supplying arteries. Until now, the risk of this intervention can only be estimated by invasive diagnostics including the risk of cerebrovascular accidents. METHODS AND RESULTS:As a supporting tool, a comput...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.08.021

    authors: Roessler FC,Reith W,Siegel G

    更新日期:2006-11-06 00:00:00

  • Cytosolic prostaglandin E2 synthase (cPGES) expression is decreased in discrete cortical regions in psychiatric disease.

    abstract::The number of adults in the US affected by bipolar disorder, depression, or schizophrenia is approaching 15 million. Despite decades of research, etiologies of these illnesses remain elusive. Theories of aberrant brain morphology, neurotransmission, and signal conduction have provided the heuristic framework for a lar...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.05.048

    authors: Maida ME,Hurley SD,Daeschner JA,Moore AH,O'Banion MK

    更新日期:2006-08-04 00:00:00

  • MicroRNA overexpression increases cortical neuronal vulnerability to injury.

    abstract::Previously we reported that several microRNAs (miRNA) are upregulated following experimentally induced traumatic brain injury (TBI) using both in vivo and in vitro approaches. Specific miRNAs were found to be sensitive to therapeutic hypothermia and may therefore be important targets for neuroprotective strategies. In...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.08.011

    authors: Truettner JS,Motti D,Dietrich WD

    更新日期:2013-10-02 00:00:00

  • The entopeduncular nucleus regulates muscle tone in genetically spastic rats: role of substance P and gamma-aminobutyric acid.

    abstract::Microinjections of the substance P (SP) antagonist (D-pro2,D-phe7,D-trp9)-SP, or the gamma-aminobutyric acid (GABA) agonist, muscimol, into the entopeduncular nucleus reduced muscle tone in genetically spastic rats in a dose- and time-dependent manner. Similar injections into the ventral thalamus, zona incerta or amyg...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90564-r

    authors: Turski L,Klockgether T,Turski WA,Schwartz M,Sontag KH

    更新日期:1990-02-19 00:00:00

  • Hippocampus activation related to 'real-time' processing of visuospatial change.

    abstract::The delay associated with cerebral processing time implies a lack of real-time representation of changes in the observed environment. To bridge this gap for motor actions in a dynamical environment, the brain uses predictions of the most plausible future reality based on previously provided information. To optimise th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2016.10.010

    authors: Beudel M,Leenders KL,de Jong BM

    更新日期:2016-12-01 00:00:00

  • Acupuncture inhibits microglial activation and inflammatory events in the MPTP-induced mouse model.

    abstract::Using a mouse model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease (PD), this study investigated on the neuroprotective effects of acupuncture by examining whether acupuncture contributed to inhibiting microglial activation and inflammatory events. C57BL/6 mice were treated with MPT...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.10.089

    authors: Kang JM,Park HJ,Choi YG,Choe IH,Park JH,Kim YS,Lim S

    更新日期:2007-02-02 00:00:00

  • Axonal regeneration in dorsal spinal roots is accelerated by peripheral axonal transection.

    abstract::Regeneration of crushed axons in rat dorsal spinal roots was measured to investigate the transganglionic influence of an additional peripheral axonal injury. The right sciatic nerve was cut at the hip and the left sciatic nerve was left intact. One week later, both fifth lumbar dorsal roots were crushed and subsequent...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91096-1

    authors: Richardson PM,Verge VM

    更新日期:1987-05-19 00:00:00

  • Neuroprotection and immunomodulation in the gut of parkinsonian mice with a plasmalogen precursor.

    abstract::Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. It is typically associated with motor symptoms originating from the degeneration of nigrostriatal dopamine (DA) neurons. Early stages of PD have been associated with an alteration in DA production in intestinal DAergic neurons alon...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.146460

    authors: Nadeau J,Smith T,Lamontagne-Proulx J,Bourque M,Al Sweidi S,Jayasinghe D,Ritchie S,Di Paolo T,Soulet D

    更新日期:2019-12-15 00:00:00

  • Central leptin suppresses splenic lymphocyte functions through activation of the corticotropin-releasing hormone-sympathetic nervous system.

    abstract::Leptin is one of the key afferent signals that regulate food intake and energy expenditure by acting on specific receptors in the hypothalamus. Recently, leptin was reported to activate the peripheral immune system by acting directly on lymphocytes. To elucidate the brain-mediated participation of leptin in the modula...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)02409-9

    authors: Okamoto S,Irie Y,Ishikawa I,Kimura K,Masayuki Saito

    更新日期:2000-02-07 00:00:00

  • Guanethidine adrenergic neuropathy: an animal model of selective autonomic neuropathy.

    abstract::Chronic administration of guanethidine to adult rats induces a selective autoimmune adrenergic neuropathy. Physiological and biochemical features of this disorder in the peripheral nervous system were explored in young adult Sprague-Dawley rats given daily intraperitoneal guanethidine monosulfate for 5 weeks. Control ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90720-2

    authors: Zochodne DW,Ward KK,Low PA

    更新日期:1988-09-27 00:00:00

  • CB1 cannabinoid receptor agonist mouse VD-hemopressin(α) produced supraspinal analgesic activity in the preclinical models of pain.

    abstract::Mouse VD-hemopressin(α) (VD-Hpα) is an undecapeptide that selectively activates CB1 cannabinoid receptor in in vitro functional tests, and exerts CB1-mediated central antinociception in the mouse tail-flick assay. The aim of the present study was to further investigate the analgesic properties of supraspinal mouse VD-...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2017.12.013

    authors: Zheng T,Zhang R,Zhang T,Zhang MN,Xu B,Song JJ,Li N,Tang HH,Wang P,Wang R,Fang Q

    更新日期:2018-02-01 00:00:00

  • Ontogenesis of proenkephalin products in rat striatum and the inhibitory effects of low-level lead exposure.

    abstract::Certain developmental abnormalities have been associated with environmental exposure to lead and our previous studies have indicated that the endogenous opioid system is disrupted by this metal. In connection with this we report the ontogeny of proenkephalin products in the rat striatum determined by combined HPLC and...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(85)90070-7

    authors: Bailey C,Kitchen I

    更新日期:1985-09-01 00:00:00

  • Dissociation of IGF2 and H19 imprinting in human brain.

    abstract::The human IGF2 and H19 genes are imprinted in most normal tissues. Alterations of genomic imprinting or loss of imprinting (LOI) have been observed in a number of malignant tumors. Although LOI has been linked to tumorigenesis, loss of IGF2 imprinting has also been observed in choroid plexus and leptomeninges in norma...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00783-5

    authors: Pham NV,Nguyen MT,Hu JF,Vu TH,Hoffman AR

    更新日期:1998-11-09 00:00:00

  • Involvement of nitric oxide in the induction of interleukin-1 beta in microglia.

    abstract::In response to in vitro stimulation with lipopolysaccharide (LPS), microglia induce the production of the inflammatory cytokine interleukin-1 beta (IL-1β) together with nitric oxide (NO) and superoxide anion (O2(-)). Here we investigated the role of NO and O2(-) in the signaling mechanism by which IL-1β is induced in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.08.030

    authors: Sudo K,Takezawa Y,Kohsaka S,Nakajima K

    更新日期:2015-11-02 00:00:00

  • Nipecotic acid, an uptake blocker, prevents fading of the gamma-aminobutyric acid effect.

    abstract::In rats under urethane, iontophoretic applications of GABA (30-60 nA) in the str. pyramidale of CA1, showed a rapidly fading inhibitory effect. By contrast, GABA had a well-maintained inhibitory effect in str. radiatum. During iontophoresis of nipecotic acid (30-85 nA) identical applications of GABA in str. pyramidale...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91309-0

    authors: Dalkara T

    更新日期:1986-02-26 00:00:00

  • Intraventricular carbachol mimics the phase-shifting effect of light on the circadian rhythm of wheel-running activity.

    abstract::Intraventricular injections of carbachol, a cholinergic agonist, into free-running mice can cause phase dependent phase shifts, in both directions, in the circadian rhythm of wheel-running activity. These effects mimic the action of light in entraining the circadian pacemaker, and suggest that acetylcholine may play a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90059-7

    authors: Zatz M,Herkenham MA

    更新日期:1981-05-11 00:00:00

  • Cytoarchitectonic distribution of zinc in the hippocampus of man and the rat.

    abstract::Zinc was measured in whole hippocampus and in hippocampal sub-regions by stable-isotope dilution mass spectrometry. In both man and the rat, the most zinc (102-145 ppm, dry weight) was found in the hilar region, the least (27-35) in the fimbria. The amount of zinc directly associated with mossy-fiber axons was estimat...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90858-2

    authors: Frederickson CJ,Klitenick MA,Manton WI,Kirkpatrick JB

    更新日期:1983-08-29 00:00:00

  • Serotonergic antagonists impair arousal-induced phase shifts of the circadian system of the syrian hamster.

    abstract::Single episodes of arousal of Syrian hamsters 2 h before projected activity onset (i.e., CT 10) phase-advanced their free-running circadian rhythm of wheel-running. Serial arousal once every 23 h or once every 23.5 h for 7 days caused large composite phase-advances to the wheel-running rhythm, the latter period being ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01314-8

    authors: Sumova A,Maywood ES,Selvage D,Ebling FJ,Hastings MH

    更新日期:1996-02-12 00:00:00