Ultrastructural evidence for peptidergic innervation of the apical region of frog olfactory epithelium.

abstract：:When one eye of a rat is removed at birth an increased projection to the brain is found from the remaining eye. This projection arises from the whole retina and mainly from ganglion cells which project to only one hemisphere of the brain. In the normal course of development many of these cells die and the uncrossed pr...

journal_title：Brain research

authors： Jeffery G,Perry VH

更新日期：1981-08-01 00:00:00

abstract：:This study investigated the long-lasting effects of chronic ethanol consumption on the distribution of Schaffer collateral-commissural (SCH/COM) afferents within stratum radiatum of rat hippocampal CA1. Experimental animals were fed an ethanol-containing liquid diet for 20 weeks but were withdrawn from the special die...

journal_title：Brain research

authors： Abraham WC,Manis PB,Hunter BE,Zornetzer SF,Walker DW

更新日期：1982-04-08 00:00:00

abstract：:Hypothalamic stimulation generally inhibits baroreflex-induced bradycardia. However, we have noted discrete areas of the rat hypothalamus which facilitate reflex bradycardia. The effects of hypothalamic stimulation on baroreflex-induced changes in heart rate were investigated in urethane-anesthetized rats (1.2 g/kg, i...

journal_title：Brain research

authors： Pardini BJ,Patel KP,Schmid PG,Lund DD

更新日期：1986-10-08 00:00:00

abstract：:Chronic administration of caffeine (s.c. for a period of 14 days in escalating doses of 10-70 mg/kg) increased the sensitivity of rat cerebral cortical neurons to the inhibitory action of microiontophoretically applied adenosine. The sensitivity of spontaneously firing rat cerebral cortical neurons in caffeine-treated...

journal_title：Brain research

authors： Lin Y,Phillis JW

更新日期：1990-06-18 00:00:00

abstract：:Perfusion of artificial CSF from a lateral ventricle to the cerebral cortical subarachnoid space in anaesthetized cats was used to study the contribution of the cerebral cortex to the concentration of 5-hydroxyindoleacetic acid (5-HIAA) in CSF. The technique did not cause rupture of the meninges. The use of [14C]5-HIA...

journal_title：Brain research

authors： Min-Chu L,Mackenna BR,Watt JA

更新日期：1981-03-23 00:00:00

abstract：:The possible involvement of protein kinase A (PKA) in the muscarinic inhibition of the slow afterhyperpolarizing current (IAHP) was investigated in rat hippocampal pyramidal cells. IAHP was recorded using the whole cell method in hippocampal slices, and Rp-cAMPS, a PKA antagonist, was applied intracellularly. The inhi...

journal_title：Brain research

authors： Blitzer RD,Wong T,Nouranifar R,Landau EM

更新日期：1994-05-23 00:00:00

abstract：:Previous research has demonstrated that in the Siberian hamster, both photoperiod and estrous cyclicity alter the profile of noradrenergic activity with the paraventricular nucleus of the hypothalamus (PVN), and that noradrenergic activity is correlated with changes in circulating levels of prolactin. Work from our la...

journal_title：Brain research

authors： Dodge JC,Badura LL

更新日期：2004-08-06 00:00:00

abstract：:Embryonic day 15 rostral tectum (presumptive superior colliculus) was transplanted into the occipital cortex of newborn rats. One to two months later, the transplants were visualized and injected with either horseradish peroxidase (HRP) or wheat germ agglutinin conjugated with HRP (WGA/HRP). After the appropriate surv...

journal_title：Brain research

authors： Sharkey MA,Steedman JG,Lund RD,Dom RM

更新日期：1987-01-01 00:00:00

abstract：:Expertise offers a unique insight into how our brain functions. The purpose of this experiment was to determine if motor system activity and functional connectivity between the cognitive system and sensorimotor system is differentially modulated by an individual's level of expertise. This goal was achieved through the...

journal_title：Brain research

authors： Tomasino B,Maieron M,Guatto E,Fabbro F,Rumiati RI

更新日期：2013-12-02 00:00:00

abstract：:Ovine corticotropin releasing factor (CRF) given intracerebroventricularly to rhesus monkeys at doses of 0.1-1 microgram/kg activates the pituitary-adrenal axis. The increases of plasma cortisol concentrations after intraventricular injection of CRF were similar to those observed after intravenous administration of th...

journal_title：Brain research

authors： Rock JP,Oldfield EH,Schulte HM,Gold PW,Kornblith PL,Loriaux L,Chrousos GP

更新日期：1984-12-10 00:00:00

abstract：:We report an fMRI experiment on deductive reasoning with acoustically presented problems. Twelve volunteers received problems in which an acoustic stimulus came from the left or the right of another stimulus. The participants then heard a third stimulus coming from the left or the right of one of the proceeding stimul...

journal_title：Brain research

authors： Fangmeier T,Knauff M

更新日期：2009-01-16 00:00:00

abstract：:The objective of this study was to determine whether the aging process influences the changes in the electrophysiological properties of motoneurons that occur as a consequence of axotomy. Accordingly, using intracellular recording and stimulating techniques, the basic electrical properties of control (unaxotomized) an...

journal_title：Brain research

authors： Yamuy J,Engelhardt JK,Morales FR,Chase MH

更新日期：1992-01-20 00:00:00

abstract：:The optic nerve of anesthetized cats was completely cut and the autologous sciatic nerve was transplanted. Sixty days later some populations of retinal ganglion cells were shown to regenerate the axon with retrograde HRP labeling. We verified that ganglion cells that had projected to the lateral geniculate nucleus (LG...

journal_title：Brain research

authors： Watanabe M,Sawai H,Fukuda Y

更新日期：1991-09-27 00:00:00

abstract：:Lysosomal storage diseases are a heterogeneous group of hereditary disorders characterized by a deficiency in lysosomal function. Although these disorders differ in their etiology and phenotype those that affect the nervous system generally manifest as a profound deterioration in neurologic function with age. Over the...

journal_title：Brain research

authors： Phinney DG,Isakova IA

更新日期：2014-07-21 00:00:00

abstract：:Myelination is an important process in brain development, and delays or abnormalities in this process have been associated with a number of conditions including autism, developmental delay, attention deficit disorder, and schizophrenia. Myelination can be sensitive to developmental experience; however, although the ad...

journal_title：Brain research

authors： Markham JA,Herting MM,Luszpak AE,Juraska JM,Greenough WT

更新日期：2009-09-08 00:00:00

abstract：:gamma-L-Glutamyl-L-aspartic acid (gamma-LGLA) has been isolated from Datura stramonium; its structure has been determined and it was then synthesized. In male Swiss mice intraperitoneal administration of the natural peptide (125 nmol/kg) or of the synthetic peptide (25-2500 nmol/kg) 24 h after acquisition of a Y-maze ...

journal_title：Brain research

authors： Ungerer A,Schmitz-Bourgeois M,Mélan C,Boulanger Y,Reinbolt J,Amiri I,de Barry J

更新日期：1988-04-19 00:00:00

abstract：:As in many humans suffering from lupus erythematosus, the development of systemic autoimmunity and inflammation in Fas-deficient MRL-lpr mice is accompanied by CNS dysfunction of unknown etiology. Experimental studies revealed infiltration of lymphoid cells into the choroid plexus, reduced neuronal complexity, retarde...

journal_title：Brain research

authors： Ballok DA,Millward JM,Sakic B

更新日期：2003-02-28 00:00:00

abstract：:Choline molecules are needed for the synthesis of acetylcholine and phospholipids in the mammalian brain. An enzymatic activity capable of forming lecithin (phosphatidylcholine) from the step-by-step methylation of phosphatidylethanolamine is identified in the bovine brain. This enzyme(s), phosphatidylethanolamine-N-m...

journal_title：Brain research

authors： Blusztajn JK,Zeisel SH,Wurtman RJ

更新日期：1979-12-28 00:00:00

abstract：:Spreading depression (SD) is characterized by a transient breakdown of neuronal function concomitant with a massive failure of ion homeostasis. It is a phenomenon that can be induced in neocortical tissue by raising excitability, e.g. injection of K(+), application of glutamatergic agonists, or blocking Na(+)/K(+) ATP...

journal_title：Brain research

authors： Köhling R,Koch UR,Hagemann G,Redecker C,Straub H,Speckmann EJ

更新日期：2003-06-13 00:00:00

abstract：:Humans flexibly adapt their behavior using feedback from their environment. This ability is impaired in old age, but recent research suggests this mainly concerns processing of negative feedback and that positive feedback might be spared. The aim of this study was to test this idea of an age-related positivity bias ag...

journal_title：Brain research

authors： Ferdinand NK

更新日期：2019-08-15 00:00:00

abstract：:The discriminative stimulus properties of ethanol are functionally regulated by ionotropic GABA(A) and NMDA receptors in specific limbic brain regions including the nucleus accumbens, amygdala, and hippocampus, as determined by microinjection studies. The purpose of the present work was to further investigate potentia...

journal_title：Brain research

authors： Besheer J,Schroeder JP,Stevenson RA,Hodge CW

更新日期：2008-09-26 00:00:00

abstract：:In most cases obesity, a major risk factor for diabetes mellitus type 2 and other associated chronic diseases, is generated by excessive eating. For a better understanding of eating behavior, it is necessary to determine how it is modulated by factors such as the calorie content of food, satiety and gender. Twelve hea...

journal_title：Brain research

authors： Frank S,Laharnar N,Kullmann S,Veit R,Canova C,Hegner YL,Fritsche A,Preissl H

更新日期：2010-09-02 00:00:00

abstract：:To determine whether the idiosyncratic distribution of transduction mechanisms for bitter tastants in rat taste receptor cells (TRCs) could be inferred from the neural activity they evoke, single neuron responses to ten bitter-tasting compounds were recorded from rat glossopharyngeal (n = 30) and chorda tympani (n = 2...

journal_title：Brain research

authors： Dahl M,Erickson RP,Simon SA

更新日期：1997-05-09 00:00:00

abstract：:The effects of acute ethanol exposure of chick spinal cord neurons were studied in tissue culture, using whole-cell voltage-clamp techniques. Results indicate that ethanol produces a persistent increase in the sensitivity of spinal neurons to GABA and glycine, with no change in input resistance or resting membrane pot...

journal_title：Brain research

authors： Celentano JJ,Gibbs TT,Farb DH

更新日期：1988-07-12 00:00:00

abstract：:Cell death was due to activation of the receptor responsive to N-methyl-D-aspartate (NMDA). Even during a 30-min incubation, glutamate toxicity was unaffected by 5 microM CNQX and was greater than 90% blocked by 160 nM MK-801, a specific antagonist of the NMDA receptor. The extent of toxicity was dependent on the age ...

journal_title：Brain research

authors： Eimerl S,Schramm M

更新日期：1991-09-27 00:00:00

abstract：:Lesions to the ventromedial hypothalamus (VMH) inhibit receptive sexual behavior in the whiptail lizard, Cnemidophorus uniparens, an all-female species. All lesions to the VMH that effectively abolished receptivity specifically damaged the dorsal lateral VMH, an area containing high concentrations of estrogen receptor...

journal_title：Brain research

authors： Kendrick AM,Rand MS,Crews D

更新日期：1995-05-22 00:00:00

abstract：:The distributions and inductions of Cu/Zn superoxide dismutase (SOD), neuronal and endothelial nitric oxide (NO) synthase (nNOS and eNOS), and nitrotyrosine (NT) were immunohistochemically examined in rabbit spinal cords after 5 and 15 min of transient ischemia. The neurons in the anterior horns (AH) were selectively ...

journal_title：Brain research

authors： Watanabe M,Sakurai M,Abe K,Aoki M,Sadahiro M,Tabayashi K,Okamoto K,Shoji M,Itoyama Y

更新日期：1996-09-02 00:00:00

abstract：:In order to establish the basic connectivity of physiologically identified somatosensory regions of the thalamus and telencephalon in the pigeon, injections of wheatgerm agglutinin-horseradish peroxidase were made under electrophysiological control and the projections were charted following conventional neurohistochem...

journal_title：Brain research

authors： Wild JM

更新日期：1987-06-02 00:00:00

abstract：:In our previous study, we have found that leucine-rich repeats and immunoglobulin-like domains 1(LRIG1) can improve the chemosensitivity in U251 cells whereas the role of LRIG1 in multidrug resistance (MDR) remains unknown. Here, we reported that LRIG1 can reverse MDR by inhibiting epidermal growth factor (EGF) recept...

journal_title：Brain research

authors： Liu B,Guo Z,Dong H,Daofeng T,Cai Q,Ji B,Zhang S,Wu L,Wang J,Wang L,Zhu X,Liu Y,Chen Q

更新日期：2015-06-22 00:00:00

abstract：:We have investigated the possibility that there is a correlation between female sexual receptivity and CNS serotonergic activity. In ovariectomized rats primed with a submaximal steroid regime of 2 micrograms oestradiol benzoate (OB) plus 0.2 mg progesterone (P), so that only a proportion were receptive, the 5-hydroxy...

journal_title：Brain research

authors： Wilson CA,Hunter AJ

更新日期：1985-05-06 00:00:00