Synthesis of lecithin (phosphatidylcholine) from phosphatidylethanolamine in bovine brain.

abstract：:An antagonist to amino acid evoked excitation, gamma-D-glutamylglycine (gamma-DGG) inhibits, dose-dependently, nociceptive C-fibre evoked field potentials and neuronal discharges in single nociceptive neurons in rat spinal cord. It is concluded that amino acids are possible transmitter substance(s) in nociceptive affe...

journal_title：Brain research

authors： Schouenborg J,Sjölund BH

更新日期：1986-08-06 00:00:00

abstract：:Averaged evoked potentials and unitary discharges in response to tooth pulp and acoustic click stimuli were recorded from the hippocampus of freely moving rats. The spatial distribution of evoked field responses to tooth pulp stimulation and acoustic clicks were identical. Averaged evoked potentials consisted of a lar...

journal_title：Brain research

authors： Brankack J,Buzsáki G

更新日期：1986-07-23 00:00:00

abstract：:To determine if aging in rats is associated with insensitivity of cerebral tissue to thyroid hormones (TH), the expression of a TH responsive protein or (THRP) in cerebral tissue was studied in male Fischer rats at 4, 12 and 24 months of age during euthyroid, hypothyroid and hyperthyroid states. The basal levels of TH...

journal_title：Brain research

authors： Mooradian AD,Li J,Shah GN

更新日期：1998-05-18 00:00:00

abstract：:This freeze-fracture study examines the development of myelinated fibers in the rat optic nerve. Axolemma of optic nerve fibers were studied before, during, and after myelination. At birth, the optic nerve is composed entirely of non-myelinated (premyelinated) axons, while in the adult, virtually all fibers acquire co...

journal_title：Brain research

authors： Black JA,Foster RE,Waxman SG

更新日期：1982-10-28 00:00:00

abstract：:A review of the available literature reveals that proliferation of ependyma occurs during embryological and early postnatal periods of development. Turnover, however, declines significantly during postnatal life and only low levels of residual activity persist into adulthood under normal conditions. In some regions of...

journal_title：Brain research

authors： Bruni JE,Del Bigio MR,Clattenburg RE

更新日期：1985-04-01 00:00:00

abstract：:The reactivity of dopaminergic (DA) terminals in the nucleus accumbens was investigated in male rats submitted to tail-pinch or various social interactions. The DA activity was assessed by measurement of the presynaptic metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) by using differential pulse voltammetry in free m...

journal_title：Brain research

authors： Louilot A,Le Moal M,Simon H

更新日期：1986-11-12 00:00:00

abstract：:The mechanism(s) underlying age-associated diminutions in the rat striatal D2 dopamine receptor (D2-receptor) number was investigated. The levels of D2-receptor mRNA in 4-, 12- and 18-month-old rat striata were found not to change. In contrast, the levels of 110 kDa protein, labeled with a D2-receptor specific antibod...

journal_title：Brain research

authors： Sakata M,Farooqui SM,Prasad C

更新日期：1992-03-20 00:00:00

abstract：:Single episodes of arousal of Syrian hamsters 2 h before projected activity onset (i.e., CT 10) phase-advanced their free-running circadian rhythm of wheel-running. Serial arousal once every 23 h or once every 23.5 h for 7 days caused large composite phase-advances to the wheel-running rhythm, the latter period being ...

journal_title：Brain research

authors： Sumova A,Maywood ES,Selvage D,Ebling FJ,Hastings MH

更新日期：1996-02-12 00:00:00

abstract：:Synapses from Mauthner to giant fibers in the hatchetfish are chemically transmitting excitatory axo-axonic synapses located in the medulla. The synapses are 4--10 mum in diameter and easily identified for electron microscopy. Presynaptic vesicles are clustered near the contact regions and are round, clear and 40-60 n...

journal_title：Brain research

authors： Model PG,Highstein SM,Bennett MV

更新日期：1975-11-14 00:00:00

abstract：:Three types of hyperpolarization in response to applied acetylcholine (ACh) were observed in 4 identified neurones (RP1, RP2, RP3 and RP4) in the right parietal ganglion of the African giant snail, Achatina fulica Férussac. In order to clarify the ionic mechanisms of these responses, the neurones were voltage-clamped ...

journal_title：Brain research

authors： Furukawa Y,Kobayashi M

更新日期：1986-05-28 00:00:00

abstract：:Rats anticipate a scheduled daily meal by entrainment of a circadian pacemaker separate from the light-entrainable circadian pacemaker located in the suprachiasmatic nuclei (SCN). The site and molecular mechanisms of the food-entrainable pacemaker are unknown. The intrinsic period (tau) of the SCN pacemaker is signifi...

journal_title：Brain research

authors： Mistlberger RE,Marchant EG,Kippin TE

更新日期：2001-11-23 00:00:00

abstract：:Male rats were treated with barbital supplied in their drinking water (daily dose around 200 mg/kg) for 50 weeks. When the treatment was stopped (day 0) spontaneous convulsions were monitored for the first 3 days of the abstinence. On day 3 a convulsion was induced by electricity in half of the rats (controls and barb...

journal_title：Brain research

authors： Wahlström G

更新日期：1983-05-05 00:00:00

abstract：:The present study aimed to evaluate the therapeutic potential of apocynin, an NADPH oxidase assembly inhibitor, on traumatic brain injury. Rat traumatic brain injury (TBI) was performed using a weight drop model. Apocynin (100mg/kg) was injected into the intraperitoneal space 15 min before TBI. Reactive oxygen species...

journal_title：Brain research

authors： Choi BY,Jang BG,Kim JH,Lee BE,Sohn M,Song HK,Suh SW

更新日期：2012-10-24 00:00:00

abstract：:Multiple sclerosis patients typically experience increased pain that is relatively insensitive to opiate treatment. The mechanistic basis for this increased nociception is currently poorly understood. In the present study, we utilized the Theiler's murine encephalomyelitis virus (TMEV) model of MS to examine possible ...

journal_title：Brain research

authors： Lynch JL,Alley JF,Wellman L,Beitz AJ

更新日期：2008-01-29 00:00:00

abstract：:Male Wistar rats were anaesthetized, injected intracisternally (i.c.) with saline or colchicine and were decapitated at various time intervals. Trunk blood was collected for the determination of immunoreactive adrenocorticotropic hormone (ACTHi) by radioimmunoassay (RIA) and of corticosterone by a fluorometric assay. ...

journal_title：Brain research

authors： Berkenbosch F,Tilders FJ

更新日期：1988-03-01 00:00:00

abstract：:The distribution of iron in the brain of a vocal learning parrot, the budgerigar (Melopsittacus undulatus), was examined using iron histochemistry. In mammals, iron is a highly specific stain for the dorsal and ventral pallidal subdivision as well as specific cell groups in the brainstem, including the substantia nigr...

journal_title：Brain research

authors： Roberts TF,Brauth SE,Hall WS

更新日期：2001-12-07 00:00:00

abstract：:Natural food sources constitute a promising source of new compounds with neuroprotective properties, once they have the ability to reach the brain. Our aim was to evaluate the brain accessibility of quercetin, epigallocatechin gallate (EGCG) and cyanidin-3-glucoside (C3G) in relation to their neuroprotective capabilit...

journal_title：Brain research

authors： Pogačnik L,Pirc K,Palmela I,Skrt M,Kim KS,Brites D,Brito MA,Ulrih NP,Silva RF

更新日期：2016-11-15 00:00:00

abstract：:Recently, the gene encoding the cerebrovascular and neuritic plaque amyloid, a pathologic stigma of Alzheimer's disease (AD), has been molecularly cloned and mapped to human chromosome 21, band q21. Changes in the brains of individuals with trisomy 21 (Down syndrome, DS) over 35 years of age closely resemble AD neurop...

journal_title：Brain research

authors： Reeves RH,Robakis NK,Oster-Granite ML,Wisniewski HM,Coyle JT,Gearhart JD

更新日期：1987-09-01 00:00:00

abstract：:We describe a method to produce frog olfactory epithelium with a population of developmentally synchronized receptor cells suitable for electrophysiological studies. The epithelium is ablated with ZnSO4 and allowed to regenerate for 10 days. Generation of new cells is then blocked by continuous treatment with hydroxyu...

journal_title：Brain research

authors： Lidow MS,Gesteland RC,Shipley MT,Kleene SJ

更新日期：1987-02-01 00:00:00

abstract：:Tetanic stimulation of fibers in the hippocampal slice preparation produces long-term potentiation (LTP) and also decreases the in vitro incorporation of phosphate into the alpha subunit of pyruvate dehydrogenase (alpha PDH). This paper describes 6 experiments that were undertaken to replicate this observation. Hippoc...

journal_title：Brain research

authors： Hoch DB,Dingledine RJ,Wilson JE

更新日期：1984-06-04 00:00:00

abstract：:To determine if ventrolateral periaqueductal gray contains neurons that selectively increase their discharge activity before and during rapid eye movement (REM) sleep, and hence might furnish GABAergic inhibition of monoaminergic neurons, we recorded the extracellular activity of 33 neurons across sleep-wakefulness in...

journal_title：Brain research

authors： Thakkar MM,Strecker RE,McCarley RW

更新日期：2002-08-02 00:00:00

abstract：:Increasing evidence have shown that beta-amyloid (Abeta) induced hyperphosphorylation of tau, which eventually resulted in the disruption of microtubule (MT) integrity. Cyclin-dependent kinase 5 (CDK5) and its activator p35 are required for neurite outgrowth. The cleavage of p35 to p25, mediated by calpain and calcium...

journal_title：Brain research

authors： Chen X,Huang T,Zhang J,Song J,Chen L,Zhu Y

更新日期：2008-03-20 00:00:00

abstract：:The tegmentopontine reticular nucleus (nucleus of Bechterew) plays a crucial role in the generation of horizontal saccades and smooth pursuit movement of the eyes. The evolution of Alzheimer's disease-related cytoskeletal pathology was studied of this nucleus was studied in 27 autopsy cases at different stages of the ...

journal_title：Brain research

authors： Rüb U,Schultz C,Del Tredici K,Braak H

更新日期：2001-07-27 00:00:00

abstract：:The rostral brainstem and thalamus of awake cats were studied for depth correlates of a surface-recorded midlatency auditory evoked potential, wave "A', with a latency range of 17-25 ms. In response to clicks or pure tones, midlatency potentials were recorded from the level of the cuneiform nucleus (14-15 ms latencies...

journal_title：Brain research

authors： Hinman CL,Buchwald JS

更新日期：1983-03-28 00:00:00

abstract：:Type 2 iodothyronine deiodinase, an enzyme involved in the conversion of thyroxin to the biologically active 3,5, 3'-triiodothyronine, is highly concentrated in a group of specialized ependymal cells, tanycytes, lining the wall and floor of the third ventricle. As this distribution is highly reminiscent of the distrib...

journal_title：Brain research

authors： Fekete C,Mihály E,Herscovici S,Salas J,Tu H,Larsen PR,Lechan RM

更新日期：2000-04-17 00:00:00

abstract：:In synaptosomal preparations from rat cerebral cortex, ouabain-sensitive Rb+ uptake was stimulated by ethanol (20-80 mM). Based on differential sensitivity to ouabain, 80% of this Na+,K(+)-ATPase activity represented activity of the alpha 1 isozyme while 20% was due to the alpha 2 and/or alpha 3 isozymes (alpha 2/ alp...

journal_title：Brain research

authors： Foley TD,Rhoads DE

更新日期：1994-08-08 00:00:00

abstract：:By means of an immunohistochemical technique, we examined the neuronal induction of 72-kDa heat shock protein (HSP72) in response to methamphetamine-induced hyperthermia in the mouse hippocampus. Strong HSP72 immunoreactivity (ir) was found in the neurons of hippocampus proper, particularly in the CA1/2 and medical CA...

journal_title：Brain research

authors： Goto S,Korematsu K,Oyama T,Yamada K,Hamada J,Inoue N,Nagahiro S,Ushio Y

更新日期：1993-10-29 00:00:00

abstract：:Parkinson's disease is characterized by a loss of dopaminergic neurons in the substantia nigra and, in the most severe cases, by degeneration of mesopontine cholinergic neurons. In a monkey model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine we report that, despite a severe loss of dop...

journal_title：Brain research

authors： Herrero MT,Hirsch EC,Javoy-Agid F,Obeso JA,Agid Y

更新日期：1993-10-08 00:00:00

abstract：:Neurofilaments were assembled in vitro from the high speed supernatant of mammalian CNS homogenate in a disassembly buffer containing 4-morpholine-ethane sulfonic acid, MgCl2 and EGTA at 4 degrees C in the presence of 4 M glycerol. The assembled neurofilaments were depolymerized by dialysis against the disassembly buf...

journal_title：Brain research

authors： Iqbal K,Grundke-Iqbal I,Merz PA,Wisniewski HM,Zaidi T

更新日期：1987-07-01 00:00:00

abstract：:This work describes the change in an active electrogenesis of the command neurons responsible for defensive closure of a snail's pneumostome during elaborating, extinction and restoration of a classical conditioned defensive reflex to a tactile stimulus. Tactile stimulations applied to different parts of a snail's bod...

journal_title：Brain research

authors： Tsitolovsky LE,Babkina NV

更新日期：1992-11-06 00:00:00