Daily variations of various parameters of serotonin metabolism in the rat brain. I. Circadian variations of tryptophan-5-hydroxylase in the raphe nuclei and the striatum.

abstract：:When a pair of stimuli separated by an appropriate interval is given to the right visceropleural connective of Aplysia californica the amplitude of the second EPSP elicited in cell R15 is usually smaller than the amplitude of the first EPSP. In the present paper we show that this phenomenon, synaptic depression, can b...

journal_title：Brain research

authors： Woodson PB,Schlapfer WT,Tremblay JP,Barondes SH

更新日期：1976-06-04 00:00:00

abstract：:The studies were performed on operation material from 17- to 63-year-old patients and on fetuses at 19-23 weeks gestational age. Formaldehyde histofluorescence showed the presence of numerous perivascular adrenergic nerves around pial and intracerebral vessels, the carotid system being better supplied than the vertebr...

journal_title：Brain research

authors： Edvinsson L,Owman C,Sjöberg NO

更新日期：1976-10-22 00:00:00

abstract：:Electrophysiological studies have suggested that the excitatory actions of opioids in the hippocampal formation are mediated by inhibition of interneurons containing GABA; however, an anatomical basis for this interaction has never been established. Thus, we sought to determine the relationship between leu-enkephalin ...

journal_title：Brain research

authors： Commons KG,Milner TA

更新日期：1996-06-10 00:00:00

abstract：:Aluminum (Al) concentrations of the rat frontal cortex, parietal cortex, and hippocampus were measured by atomic absorption spectroscopy 16 days after a unilateral intracerebroventricular injection of Na gluconate, Al gluconate, or the cholinotoxin AF64A. A fourth group of rats were injected with AF64A 6 days before i...

journal_title：Brain research

authors： Szerdahelyi P,Kása P

更新日期：1988-03-22 00:00:00

abstract：:Kinins, such as bradykinin and Lys-bradykinin, are important mediators in peripheral inflammation. Although the existence of the components necessary for generating kinins has been demonstrated in the brain, a functional role of the kinin-generating system in cerebral inflammation remains to be defined. The aim of the...

journal_title：Brain research

authors： Takano M,Horie M,Yayama K,Okamoto H

更新日期：2003-07-18 00:00:00

abstract：:We previously reported that glial fibrillary acidic protein (GFAP) levels increased significantly at 3 days after stab wounds, relative to sham-operated controls, reaching a maximum of 200% of control value at 5-7 days. They then fell to near-normal values by 21 days. To determine whether these protein changes correla...

journal_title：Brain research

authors： Hozumi I,Aquino DA,Norton WT

更新日期：1990-11-26 00:00:00

abstract：:The 2009 influenza A(H1N1) pandemic led to a particularly high risk of morbidity and mortality among pregnant women. Therefore, inactivated influenza vaccines have been widely recommended for women in any period of gestation. Recent studies have shown that the peripheral adaptive immune system plays an important role ...

journal_title：Brain research

authors： Xia Y,Qi F,Zou J,Yao Z

更新日期：2014-12-10 00:00:00

abstract：:The subunit composition of α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors (AMPARs) is an important determinant of AMPAR biophysical properties and trafficking. To date, AMPAR subunit composition has been quantitatively evaluated only for the hippocampus, where different experimental approaches have yield...

journal_title：Brain research

authors： Reimers JM,Milovanovic M,Wolf ME

更新日期：2011-01-07 00:00:00

abstract：:Cyclic nucleotide phosphodiesterase-4 (PDE4) is a component of signaling pathways involved in the mediation of antidepressant activity. Of the four PDE4 subtypes, PDE4D appears to be of particular importance, given the finding that PDE4D-deficient mice exhibit an antidepressant-like behavioral phenotype. In mouse hipp...

journal_title：Brain research

authors： Dlaboga D,Hajjhussein H,O'Donnell JM

更新日期：2006-06-22 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs) react rapidly to brain and spinal cord injuries. This reaction is characterized by the retraction of cell processes, cell body swelling and increased expression of the NG2 chondroitin sulfate proteoglycan. Reactive OPCs rapidly divide and accumulate surrounding the injury site wh...

journal_title：Brain research

authors： Levine J

更新日期：2016-05-01 00:00:00

abstract：:Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation...

journal_title：Brain research

authors： Novak JC,Lovell JA,Stuesse SL,Cruce WL,McBurney DL,Crisp T

更新日期：1999-07-03 00:00:00

abstract：:The morphology of so-called interplexiform (IP) cells immunoreactive to tyrosine hydroxylase (TH) or somatostatin (SOM) in the rat retina was described in comparison with those in the carp retina. In frozen cross-sections of the rat retina, many processes of TH-like immunoreactive cells were found to extend toward the...

journal_title：Brain research

authors： Negishi K,Kato S,Teranishi T,Kiyama H,Katayama Y,Tohyama M

更新日期：1985-10-28 00:00:00

abstract：:Substance P (SP) has been proposed as a nociceptive transmitter/modulator in the dorsal horn of the spinal cord. Formalin used as a nociceptive stimulus has been shown to increase, in a biphasic manner, the amount of immunoreactive SP in the dorsal horn. The time course of the changes in substance P-like immunoreactiv...

journal_title：Brain research

authors： Holland LN,Goldstein BD

更新日期：1990-12-24 00:00:00

abstract：:We compared the relative abilities of a series of calmodulin inhibitors and protein kinase C inhibitors to influence 45Ca2+ influx through voltage-dependent Ca2+ channels in PC12, a clonal neural cell line. K+-depolarization-dependent 45Ca2+ uptake was reduced by the calmodulin inhibitors calmidazolium, trifluoperazin...

journal_title：Brain research

authors： Greenberg DA,Carpenter CL,Messing RO

更新日期：1987-02-24 00:00:00

abstract：:Effects of methamphetamine (MAP) on the extracellular neuropeptide Y (NPY) and noradrenaline (NA) levels were examined in the vicinity of the paraventricular nucleus (PVN) of freely moving rats by means of push-pull perfusion. The NA and NPY levels increased significantly in 30-60 min and reached the maximum level in ...

journal_title：Brain research

authors： Yoshihara T,Honma S,Mitome M,Honma K

更新日期：1996-01-22 00:00:00

abstract：:Previous studies showed the role of basolateral amygdala (BLA) in cannabinoid-induced antinociception. Furthermore, the nucleus accumbens (NAc) plays an important role in mediating the suppression of pain in animal models. The present study extended the role of dopamine receptors within the NAc in antinociceptive effe...

journal_title：Brain research

authors： Haghparast A,Ghalandari-Shamami M,Hassanpour-Ezatti M

更新日期：2012-08-30 00:00:00

abstract：:Previous studies have indicated that amyloid precursor protein (APP) might be a trophic agent in the nervous system, possibly through the regulation of cell adhesion and the protease/protease inhibitor activity. Additionally, APP is upregulated during the development of the nervous system. In order to further study th...

journal_title：Brain research

authors： Masliah E,Mallory M,Ge N,Saitoh T

更新日期：1992-10-16 00:00:00

abstract：:The horizontal and vertical vestibulo ocular reflex (VOR) of head tilted (het) mutant mice was compared to C57BL/6 controls. Eye movements were recorded in darkness using a temporarily attached search coil. Contributions of semicircular canal versus otolith organ signals were investigated by providing a canal only (ve...

journal_title：Brain research

authors： Harrod CG,Baker JF

更新日期：2003-05-16 00:00:00

abstract：:Hypothalamic nuclei close to the third ventricle (VIII) represent key structures in avian osmoregulation concerned with the control of salt gland activity and release of the antidiuretic hormone [Arg8]vasotocin (AVT). Nitric oxide (NO) acting as a paracrine transmitter in the hypothalamus has been shown to contribute ...

journal_title：Brain research

authors： Hübschle T,Küchenmeister I,Gerstberger R

更新日期：1999-04-17 00:00:00

abstract：:Acutely (by 48 h), as well as after one month survival, morphine (20 mg/kg) significantly potentiated the extent of noradrenergic degeneration in the forebrain of newborn rats caused by 50 mg/kg of 6-hydroxydopamine (6-OHDA) s.c. This was associated with increased regenerative sprouting in the cerebellum and pons-medu...

journal_title：Brain research

authors： Bardo MT,Schmidt RH,Bhatnagar RK

更新日期：1985-10-01 00:00:00

abstract：:Ascending and descending projections of the nucleus reticularis gigantocellularis (NRGc) were studied in the cat by the anterograde tracer, Phaseolus vulgaris leucoagglutinin. Ascending fibers from the left or the right NRGc coursed through the bilateral medial reticular formation and some of them reached the dienceph...

journal_title：Brain research

authors： Matsuyama K,Ohta Y,Mori S

更新日期：1988-09-13 00:00:00

abstract：:5-HT2 receptor binding sites were measured (by saturation binding of [3H]ketanserin) in brain tissue obtained at postmortem from 19 suicide victims with definite evidence of depression and 19 sex and age-matched control subjects. Five of the suicide victims were receiving antidepressant drugs prior to death; 13 suicid...

journal_title：Brain research

authors： Cheetham SC,Crompton MR,Katona CL,Horton RW

更新日期：1988-03-08 00:00:00

abstract：:Response conflict can be induced by priming multiple responses competing for control of action in trials. The N2 is one functionally-related cognitive control index for response conflict. And yet the underlying whiter matter neural substrates of inter-individual difference in conflict N2 remain unclear. So the aim of ...

journal_title：Brain research

authors： Gao S,Liu P,Guo J,Zhu Y,Liu P,Sun J,Yang X,Qin W

更新日期：2017-12-01 00:00:00

abstract：:Activation of the immune system in response to either infection or lipopolysaccharide (LPS) produces neurophysiological, neuroendocrine and behavioral changes. Some of the physiological consequences of LPS are mediated by endogenous opioid peptides. The following studies were designed to characterize the effects of LP...

journal_title：Brain research

authors： Yirmiya R,Rosen H,Donchin O,Ovadia H

更新日期：1994-06-13 00:00:00

abstract：:The effects of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS), a synthetic precursor of norepinephrine (NE), on the long-term potentiation (LTP) in the hippocampal mossy fiber-CA3 system was examined in urethane-anesthetized rats, the objective being to determine whether or not this drug acts as NE on the LTP. L-thr...

journal_title：Brain research

authors： Sakai N,Sasa M,Ishihara K,Komure O,Tanaka C,Takaori S

更新日期：1991-12-20 00:00:00

abstract：:Met-enkephalin-like immunoreactivity in microdialysates from the respiratory-related nucleus tractus solitarii was determined simultaneously with ventilatory responses in seven, spontaneously breathing, developing swine under conditions of normoxia, hypoxia and recovery from hypoxia for 30 min each. Assayed levels of ...

journal_title：Brain research

authors： Yan S,Zhang C,Laferrière,Moss IR

更新日期：1995-07-31 00:00:00

abstract：:The concentration of soluble glial fibrillary acidic (GFA) protein and the specific activity of glutamine synthetase (GS) were estimated in 11 central nervous system (CNS) regions of the 90-day-old rat. Marked differences were observed in the regional distribution of these astrocyte marker proteins. The striatum and s...

journal_title：Brain research

authors： Patel AJ,Weir MD,Hunt A,Tahourdin CS,Thomas DG

更新日期：1985-04-01 00:00:00

abstract：:Endogenous opioid systems (i.e. opioids and opioid receptors) play a role in regulating neural development. Using the cerebellar cortex of 6-day-old rats, the most potent opioid peptides involved with cell proliferation were assessed. In both the external germinal (granule) layer (EGL), a germinative matrix giving ris...

journal_title：Brain research

authors： Zagon IS,McLaughlin PJ

更新日期：1991-03-01 00:00:00

abstract：:The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual ...

journal_title：Brain research

authors： Golub MS,Slotkin TA,Tarantal AF,Pinkerton KE

更新日期：2007-06-02 00:00:00

abstract：:The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovarie...

journal_title：Brain research

authors： Pearson PL,Ross LR,Jacobson CD

更新日期：1993-07-16 00:00:00