Abstract:
:Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation of the left sciatic nerve. The extent to which the aging process affects the thermal hyperalgesic responsiveness of these animals was investigated. The results demonstrate that the aging process differentially alters nociceptive processing.
journal_name
Brain Resjournal_title
Brain researchauthors
Novak JC,Lovell JA,Stuesse SL,Cruce WL,McBurney DL,Crisp Tdoi
10.1016/s0006-8993(99)01522-xsubject
Has Abstractpub_date
1999-07-03 00:00:00pages
308-10issue
2eissn
0006-8993issn
1872-6240pii
S0006-8993(99)01522-Xjournal_volume
833pub_type
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