Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion.

abstract：:Chick embryos ranging in age from 4.0 to 18 days of incubation and 1-2-day-old hatchlings received injections of HRP solutions directly into the leg musculature. After survival periods of from 5 to 25 h motoneurons and cells in the spinal sensory ganglia were found to be stained with the HRP reaction product. It was f...

journal_title：Brain research

authors： Oppenheim RW,Heaton MB

更新日期：1975-11-14 00:00:00

abstract：:Prolonged exposure of opioid receptors to agonists leads to their regulation by the classical process of clathrin-dependent internalization, followed by their intracellular degradation (down regulation). We have previously shown that the opioid agonist etorphine induced an additional process of down regulation of mu-o...

journal_title：Brain research

authors： Kaplan E,Binyaminy B,Gafni M,Keren O,Sarne Y

更新日期：2011-04-22 00:00:00

abstract：:The responsiveness of the tonically firing single motor units (SMU) to Ia afferent volleys elicited by either mechanical (T-reflex) or electrical nerve stimulation (H-reflex) was tested in the extensor carpi radialis muscle (ECR) while the subjects were maintaining a steady wrist extension force using visual feedback ...

journal_title：Brain research

authors： Nafati G,Rossi-Durand C,Schmied A

更新日期：2004-08-27 00:00:00

abstract：:Diverse neuropsychiatric diseases were recently linked to specific anti-neuronal autoantibodies targeting synaptic proteins. Symptoms can range from epileptic seizures to cognitive impairment to movement disorders, commonly responding to treatment with immunotherapy. Several of these autoantibodies target inhibitory s...

journal_title：Brain research

authors： Prüss H,Kirmse K

更新日期：2018-12-15 00:00:00

abstract：:Interhemispheric connections were studied by injecting a mixture of horseradish peroxidase (HRP) and wheatgerm agglutinin conjugated with horseradish peroxidase (WGA-HRP) into multiple sites in dorsolateral occipital and parietal cortex of one cerebral hemisphere of three galagos (Galago crassicaudatus) and two owl mo...

journal_title：Brain research

authors： Beck PD,Kaas JH

更新日期：1994-07-18 00:00:00

abstract：:We have examined the saturation features (Kd and Bmax) of [3H]naloxone binding in rat brain regions in cytoarchitectonically intact tissues of naive, morphine dependent and precipitated withdrawal states using quantitative film autoradiography. Sixty-one saturation experiments in 13 regions of naive rat brains yielded...

journal_title：Brain research

authors： Geary WA 2nd,Wooten GF

更新日期：1985-12-23 00:00:00

abstract：:A major effect of volatile anesthetics is to reduce excitatory synaptic transmission. In the present study the stimulated release of glutamate under the influence of increasing concentrations of isoflurane was studied in vitro by utilizing hippocampal slices from Wistar rats. Ca(2+)-dependent release was calculated by...

journal_title：Brain research

authors： Larsen M,Grøndahl TO,Haugstad TS,Langmoen IA

更新日期：1994-11-14 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-like immunoreactivity was examined in the rat olfactory bulb by an immunohistochemical method using antiserum against the tripeptide TRH. TRH-immunoreactive neurons and neuronal processes were localized in both main and accessory olfactory bulb, including the glomerular layer, exter...

journal_title：Brain research

authors： Tsuruo Y,Hökfelt T,Visser TJ

更新日期：1988-04-26 00:00:00

abstract：:Rarely do we encounter a single odorant in our environment. Perception of odours, therefore, usually depends on the reception and neural processing of many components. However, little is known about how and where odour mixtures are processed. Evidence is presented here that suppression of one odour by another, a commo...

journal_title：Brain research

authors： Bell GA,Laing DG,Panhuber H

更新日期：1987-11-17 00:00:00

abstract：:Horseradish peroxidase (HRP, 30% solution, 0.1-0.3 mul, 72 h) was injected unilaterally into the basal striatum (STR) and the dorsal ventricular ridge (DVR) of adult turtles (Chrysemys picta) in order to demonstrate the cells of origin of some afferents to these telencephalic structures. After selective STR injection,...

journal_title：Brain research

authors： Parent A

更新日期：1976-05-21 00:00:00

abstract：:The regional distribution of proline biosynthetic enzymes, ornithine-delta-aminotransferase and delta 1-pyrroline-5-carboxylate reductase, in the rat brain, and basic conditions for proline synthesis from ornithine in rat and chicken brain slices and chicken retinas were investigated. The cerebral regions relating to ...

journal_title：Brain research

authors： Matsuzawa T,Obara Y

更新日期：1987-06-16 00:00:00

abstract：:The changes in the excitability of lumbosacral spinothalamic neurons produced by activating afferents in the trigeminal nerve using electrical or mechanical stimuli was investigated in cats anesthetized with alpha-chloralose. In most spinothalamic neurons, weak electrical stimuli or step indentations of the skin of th...

journal_title：Brain research

authors： McCreery DB,Bloedel JR,Hames EG

更新日期：1979-11-16 00:00:00

abstract：:The dominant pacemaker of the mammalian circadian clock, located in the suprachiasmatic nucleus (SCN), is of special interest for many pharmacological, physiological and immunohistological studies on angiotensins and their receptors. Based on its role in the circadian modulation of blood pressure and vasopressin relea...

journal_title：Brain research

authors： Thomas MA,Fleissner G,Stöhr M,Hauptfleisch S,Lemmer B

更新日期：2004-05-22 00:00:00

abstract：:The major initiation process of intracranial aneurysms is thought to involve endothelial dysfunction due to hemodynamic stress. Angiotensin II type 1 receptor blockers and statins improve vascular endothelium function. The effects of olmesartan and pravastatin were investigated on the development of experimental aneur...

journal_title：Brain research

authors： Kimura N,Shimizu H,Eldawoody H,Nakayama T,Saito A,Tominaga T,Takahashi A

更新日期：2010-03-31 00:00:00

abstract：:The possibility that gamma-aminobutyric acid (GABA) could modulate sympathetic neurotransmission in the cerebrovascular bed of the goat has been investigated by means of 3 experimental approaches: measurement of cerebral blood flow in the anesthetized animal, recording of isometric tension in isolated cerebral arterie...

journal_title：Brain research

authors： Miranda FJ,Torregrosa G,Salom JB,Campos V,Alabadí JA,Alborch E

更新日期：1989-07-17 00:00:00

abstract：:There are marked increases in noradrenaline (NA) release during emergence from general anesthesia induced with volatile anesthestics. These changes in NA in the posterior hypothalamus of the rat were assessed by intracranial microdialysis. Sevoflurane and halothane in equipotent concentrations were used to obtain the ...

journal_title：Brain research

authors： Chave S,Kushikata T,Ohkawa H,Ishiara H,Grimaud D,Matsuki A

更新日期：1996-01-15 00:00:00

abstract：:The role of descending monoaminergic pathways in the antinociceptive effect of baclofen following intraperitoneal (i.p.) administration was investigated by determining the effect of intrathecal (i.t.) administration of neurotoxins [6-hydroxydopamine (6-OHDA) and 5,6-dihydroxytryptamine (5,6-DHT)] and receptor antagoni...

journal_title：Brain research

authors： Sawynok J,Dickson C

更新日期：1985-05-27 00:00:00

abstract：:The effects of norepinephrine (NE) on inhibitory synaptic potentials were studied on CA1 pyramidal neurons in the hippocampal slice in vitro. Norepinephrine caused the appearance of multiple population spikes in the CA1 region of the hippocampal slice, reminiscent of the actions of gamma-aminobutyric acid (GABA) antag...

journal_title：Brain research

authors： Madison DV,Nicoll RA

更新日期：1988-02-23 00:00:00

abstract：:Patches excised from fields CA1 and CA3 of the hippocampus were used to study AMPA receptor responses to repetitive application of brief pulses of agonist. AMPA receptors in field CA1 exhibited a larger degree of paired-pulse depression and a slower recovery rate from desensitization than those from CA3 patches. Respo...

journal_title：Brain research

authors： Arai A,Lynch G

更新日期：1996-04-15 00:00:00

abstract：:Treatment with thyrotropin-releasing hormone (TRH) significantly improved survival following induction of fatal systemic anaphylaxis in mice. The protective effect was mediated centrally since survival was increased by intracerebroventricular (i.c.v.) administration of TRH at doses which had no effect when given syste...

journal_title：Brain research

authors： Amir S,Harel M,Schachar A

更新日期：1984-04-30 00:00:00

abstract：:The effects of acute ethanol exposure of chick spinal cord neurons were studied in tissue culture, using whole-cell voltage-clamp techniques. Results indicate that ethanol produces a persistent increase in the sensitivity of spinal neurons to GABA and glycine, with no change in input resistance or resting membrane pot...

journal_title：Brain research

authors： Celentano JJ,Gibbs TT,Farb DH

更新日期：1988-07-12 00:00:00

abstract：:The present study examined the effects of stereotaxic delivery of corticosterone to the amygdala on anxiety-like behavior and corticotropin-releasing factor (CRF) mRNA level in the central nucleus of the amygdala (CeA). Micropellets (30 microg) of crystalline corticosterone or cholesterol (control) were implanted bila...

journal_title：Brain research

authors： Shepard JD,Barron KW,Myers DA

更新日期：2000-04-10 00:00:00

abstract：:The dmy rat is an autosomal recessive mutant that exhibits severe myelin destruction throughout the white matter of the central nervous system. Recently, a point mutation in intron 3 of the Mrs2 has been found in the dmy rat. Mrs2 encodes an essential component of the major electrophoretic Mg(2+) influx system in mito...

journal_title：Brain research

authors： Kuwamura M,Inumaki K,Tanaka M,Shirai M,Izawa T,Yamate J,Franklin RJ,Kuramoto T,Serikawa T

更新日期：2011-05-10 00:00:00

abstract：:Adaptive behaviour requires that organisms continuously monitor the environment for potentially significant information and evaluate whether currently unattended stimuli afford a behavioural change. Here we used event-related functional magnetic resonance imaging in humans to assess the neural mechanisms underlying th...

journal_title：Brain research

authors： Gruber O,Diekhof EK,Kirchenbauer L,Goschke T

更新日期：2010-09-10 00:00:00

abstract：:The presynaptic neurotoxin omega-conotoxin (omega-CgTx) was tested for its ability to inhibit voltage-dependent calcium flux and transmitter release in rat brain synaptosomes. Conotoxin (0.001-10 microM) had no effect on calcium uptake or endogenous dopamine release from rat striatal synaptosomes in the absence of pot...

journal_title：Brain research

authors： Woodward JJ,Rezazadeh SM,Leslie SW

更新日期：1988-12-13 00:00:00

abstract：:The effect of chronic ethanol administration on the density of basket cells in the dentate gyrus of mice selectively bred for their sensitivity to acute ethanol exposure (long-sleep, LS and short-sleep, SS) was assessed in two experiments. In addition, the effect of chronic ethanol on the density of dentate granule ce...

journal_title：Brain research

authors： Scheetz AJ,Markham JA,Fifková E

更新日期：1988-09-20 00:00:00

abstract：:The putative involvement of the dopaminergic innervation of the medial part of the prefrontal cortex (PFC) in short-term memory functioning was investigated by evaluating the effects of local infusions of dopaminergic drugs into the ventral part of the medial PFC of rats in an operant delayed-matching-to-position (DMT...

journal_title：Brain research

authors： Broersen LM,Heinsbroek RP,de Bruin JP,Uylings HB,Olivier B

更新日期：1995-03-20 00:00:00

abstract：:To determine whether oculomotor internuclear neurons (INOs) establish unilateral or bilateral connections with the abducens nucleus (nVI), horseradish peroxidase (HRP) and either DAPI or Nuclear Yellow (NY) were injected into nVI and the oculomotor complex (nIII) examined for retrogradely labeled cells. Such injection...

journal_title：Brain research

authors： Maciewicz R,Phipps BS

更新日期：1983-02-28 00:00:00

abstract：:The effects of partial metabolic inhibition (induced by 2 h exposure to low concentrations of cyanide (NaCN)) on the glutamate receptor agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA)-induced excitotoxicity and elevation of free cytoplasmic Ca2+ levels ([Ca2+]i) were studied in glucose-deprived pri...

journal_title：Brain research

authors： Cebers G,Cebere A,Liljequist S

更新日期：1998-01-01 00:00:00

abstract：:Recently it was reported that there is an increase in monoamine oxidase B (MAO-B) activity in post-mortem brains of patients with Alzheimer's disease. It was postulated that this increase in MAO-B activity was due to gliosis associated with neuronal degeneration. The aim of the present investigation was to evaluate th...

journal_title：Brain research

authors： Jossan SS,Hiraga Y,Oreland L

更新日期：1989-01-09 00:00:00