Effects of two volatile anesthetics (sevoflurane and halothane) on the hypothalamic noradrenaline release in rat brain.

Abstract:

:There are marked increases in noradrenaline (NA) release during emergence from general anesthesia induced with volatile anesthestics. These changes in NA in the posterior hypothalamus of the rat were assessed by intracranial microdialysis. Sevoflurane and halothane in equipotent concentrations were used to obtain the same depth of anesthesia. NA release increased similarly with the two agents during recovery. However, NA release remained elevated longer with halothane, from which recovery was also slower.

journal_name

Brain Res

journal_title

Brain research

authors

Chave S,Kushikata T,Ohkawa H,Ishiara H,Grimaud D,Matsuki A

doi

10.1016/0006-8993(95)01080-7

subject

Has Abstract

pub_date

1996-01-15 00:00:00

pages

293-6

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(95)01080-7

journal_volume

706

pub_type

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