ASIC3-immunoreactive neurons in the rat vagal and glossopharyngeal sensory ganglia.

Abstract:

:ASIC3-immunoreactivity (ir) was examined in the rat vagal and glossopharyngeal sensory ganglia. In the jugular, petrosal and nodose ganglia, 24.8%, 30.8% and 20.6% of sensory neurons, respectively, were immunoreactive for ASIC3. These neurons were observed throughout the ganglia. A double immunofluorescence method demonstrated that many ASIC3-immunoreactive (ir) neurons co-expressed calcitonin gene-related peptide (CGRP)- or vanilloid receptor subtype 1 (VRL-1)-ir in the jugular (CGRP, 77.8%; VRL-1, 28.0%) and petrosal ganglia (CGRP, 61.7%; VRL-1, 21.5%). In the nodose ganglion, however, such neurons were relatively rare (CGRP, 6.3%; VRL-1, 0.4%). ASIC3-ir neurons were mostly devoid of tyrosine hydroxylase in these ganglia. However, some ASIC3-ir neurons co-expressed calbindin D-28k in the petrosal (5.5%) and nodose ganglia (3.8%). These findings may suggest that ASIC3-containing neurons have a wide variety of sensory modalities in the vagal and glossopharyngeal sensory ganglia.

journal_name

Brain Res

journal_title

Brain research

authors

Fukuda T,Ichikawa H,Terayama R,Yamaai T,Kuboki T,Sugimoto T

doi

10.1016/j.brainres.2006.01.039

subject

Has Abstract

pub_date

2006-04-07 00:00:00

pages

150-5

issue

1

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(06)00108-9

journal_volume

1081

pub_type

杂志文章
  • Three dimensional representation of bulbo-pontine respiratory networks architecture from unit density maps.

    abstract::Results of the preceding paper32 suggest that bulbo-pontine respiration related units (RRU) could be classed into 4 populations according to the relation of their peak firing frequency to the respiratory cycle: one inspiratory (I) and 3 expiratory (E) (early, mid and late). A further study of their spatial distributio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(76)90668-5

    authors: Vibert JF,Bertrand F,Denavit-Saubié M,Hugelin A

    更新日期:1976-09-17 00:00:00

  • The cholinergic neurotoxin ethylcholine mustard aziridinium (AF64A) induces an increase in MAO-B activity in the rat brain.

    abstract::Recently it was reported that there is an increase in monoamine oxidase B (MAO-B) activity in post-mortem brains of patients with Alzheimer's disease. It was postulated that this increase in MAO-B activity was due to gliosis associated with neuronal degeneration. The aim of the present investigation was to evaluate th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)91249-3

    authors: Jossan SS,Hiraga Y,Oreland L

    更新日期:1989-01-09 00:00:00

  • GABAB-mediated modulation of ionic conductances in type I hair cells isolated from guinea-pig semicircular canals.

    abstract::Mammalian vestibular type I hair cells (VIHCs) are innervated by an afferent synaptic calyx which contains vesicles and is immunoreactive for GABA. We describe here the effects of GABA on electrophysiological properties and on cytosolic free-calcium levels ([Ca2+]i) of VIHCs isolated from guinea-pig ampullae. Whole-ce...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90882-n

    authors: Lapeyre PN,Kolston PJ,Ashmore JF

    更新日期:1993-04-23 00:00:00

  • Specificity of glucocorticoid receptor primary antibodies for analysis of receptor localization patterns in cultured cells and rat hippocampus.

    abstract::After glucocorticoid stimulation, glucocorticoid receptors (GRs) are translocated to the nucleus to modulate transcription of glucocorticoid target genes. The subcellular distribution and trafficking of GR in cultured cells has been studied quite intensively using several techniques. However, the intracellular localiz...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.03.052

    authors: Sarabdjitsingh RA,Meijer OC,de Kloet ER

    更新日期:2010-05-17 00:00:00

  • Tachykinins protect cholinergic neurons from quinolinic acid excitotoxicity in striatal cultures.

    abstract::The neuroprotective effect of tachykinins against excitotoxic death of cholinergic neurons was studied in rat striatal cell cultures. Quinolinic acid (QUIN) and kainic acid (KA) produced a dose dependent decrease in choline acetyltransferase activity, but KA was more potent. Our results show that substance P (SP) tota...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(96)00879-7

    authors: Calvo N,Reiriz J,Pérez-Navarro E,Alberch J

    更新日期:1996-11-18 00:00:00

  • Thalamic nuclei that project to reptilian telencephalon lack GABA and GAD immunoreactive neurons and puncta.

    abstract::Brains of reptiles, Caiman crocodilus, were processed by standard immunocytochemical methodology using a polyclonal antibody to gamma-aminobutyric acid (GABA) raised in rabbit and a polyclonal antibody to glutamic acid decarboxylase (GAD) raised in sheep. No GABA(+) or GAD(+) cells or puncta were observed over any tha...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90068-6

    authors: Pritz MB,Stritzel ME

    更新日期:1988-08-02 00:00:00

  • The lipid and protein content of cholinergic synaptic vesicles from the electric organ of Torpedo marmorata purified to constant composition: implications for vesicle structure.

    abstract::The lipid, protein, acetylcholine and ATP content of cholinergic synaptic vesicles isolated from the richly innervated electric organ of Torpedo marmorata and purified to constant composition has been determined. The number of vesicles present in the preparations has been estimated by quantitative electron microscopy ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(79)90674-7

    authors: Ohsawa K,Dowe GH,Morris SJ,Whittaker VP

    更新日期:1979-02-09 00:00:00

  • Changes in neuropeptide Y immunoreactivity in the arcuate nucleus during and after food restriction in lactating rats.

    abstract::Previous studies have demonstrated that food restriction during lactation extends the length of lactational infertility in rats. In order to determine whether Neuropeptide Y (NPY) plays a role in the increased length of lactational infertility seen in food-restricted rats, NPY immunoreactivity in the arcuate nucleus o...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00351-x

    authors: Abizaid A,Walker CD,Woodside B

    更新日期:1997-07-04 00:00:00

  • Age-effects on associative object-location memory.

    abstract::Aging is accompanied by an impairment of associative memory. The medial temporal lobe and fronto-striatal network, both involved in associative memory, are known to decline functionally and structurally with age, leading to the so-called associative binding deficit and the resource deficit. Because the MTL and fronto-...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.12.011

    authors: Meulenbroek O,Kessels RP,de Rover M,Petersson KM,Rikkert MG,Rijpkema M,Fernández G

    更新日期:2010-02-22 00:00:00

  • Synaptic adhesion molecule OBCAM; synaptogenesis and dynamic internalization.

    abstract::Opioid-binding cell adhesion molecule (OBCAM) is the member of the IgLON family, a subgroup of the immunoglobulin superfamily. In the present study, the functions and dynamics of OBCAM were investigated in hippocampal neurons in vitro. Western blotting revealed that OBCAM expression was low at early stages of culture ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.04.062

    authors: Yamada M,Hashimoto T,Hayashi N,Higuchi M,Murakami A,Nakashima T,Maekawa S,Miyata S

    更新日期:2007-08-24 00:00:00

  • Involvement of NFκB signaling in mediating the effects of GRK5 on neural stem cells.

    abstract::Nuclear factor κB (NFκB) signaling plays ubiquitous roles in inflammation, immune response and neurogenesis. G protein-coupled receptor kinase 5 (GRK5) can protect neurons from degeneration. GRK5 also mediates tumor necrosis factor-α (TNFα)-induced NFκB signaling through the phosphorylation of IκBα. Here, we show that...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.02.041

    authors: Zhang Y,Shen GL,Shangguan LJ,Yu Y,He ML

    更新日期:2015-05-22 00:00:00

  • Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation.

    abstract::Alcohols and volatile anesthetics modulate the function of cys-loop ligand-gated ion channels, binding to a putative site between transmembrane domains two and three. The extracellular linker between these two domains is important in the transduction of the gating signal from the glycine binding site to the channel ga...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.03.031

    authors: Dupre ML,Broyles JM,Mihic SJ

    更新日期:2007-06-04 00:00:00

  • Neuronal correlates of classically conditioned bradycardia in the rabbit: studies of the medial prefrontal cortex.

    abstract::Multiple-unit activity (MUA) in the agranular medial prefrontal cortex (PFC) was recorded in conscious rabbits during a classical conditioning procedure involving repeated pairings of a 4-s tone conditioned stimulus (CS) with eye shock. Prior to behavioral training, significant tone-evoked increases in prefrontal MUA ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)91435-7

    authors: Gibbs CM,Powell DA

    更新日期:1988-02-23 00:00:00

  • Dopamine uptake in serotoninergic terminals in vitro: a valuable tool for the histochemical differentiation of catecholaminergic and serotoninergic terminals in rat cerebral structures.

    abstract::An in vitro method was developed to separately visualize dopaminergic, noradrenergic and serotoninergic terminals in the cerebral, hippocampal and cerebellar cortices of the rat, by means of the glyoxylic histochemical fluorescence method. Animals were pretreated with alpha-methylparatyrosine to deplete catecholamine ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(78)90770-9

    authors: Berger B,Glowinski J

    更新日期:1978-05-19 00:00:00

  • Mechanism of the cardiovascular effects of GABAB receptor activation in the nucleus tractus solitarii of the rat.

    abstract::The effects of baclofen microinjected into the nucleus tractus solitarii (NTS) on blood pressure, heart rate and baroreflex bradycardia were studied in urethane-anesthetized rats. Baclofen caused dose-dependent pressor and tachycardic effects and inhibited the reflex bradycardia elicited by i.v. phenylephrine. The eff...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91609-k

    authors: Florentino A,Varga K,Kunos G

    更新日期:1990-12-10 00:00:00

  • Genetically determined differences in noradrenergic function: The spontaneously hypertensive rat model.

    abstract::While genetic predisposition is a major factor, it is not known how development of attention-deficit/hyperactivity disorder (ADHD) is modulated by early life stress. The spontaneously hypertensive rat (SHR) displays the behavioral characteristics of ADHD (poorly sustained attention, impulsivity, hyperactivity) and is ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.11.019

    authors: Sterley TL,Howells FM,Russell VA

    更新日期:2016-06-15 00:00:00

  • The neuromechanism underlying verbal analogical reasoning of metaphorical relations: an event-related potentials study.

    abstract::Using event-related potentials (ERPs), this study investigated the neuromechanism underlying verbal analogical reasoning of two different metaphorical relations: attributive metaphor and relational metaphor. The analogical reasoning of attributive metaphor (AM-AR) involves a superficial similarity between analogues, w...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.09.041

    authors: Zhao M,Meng H,Xu Z,Du F,Liu T,Li Y,Chen F

    更新日期:2011-11-24 00:00:00

  • Progesterone stimulates sexual behaviour in female rats by increasing 5-HT activity on 5-HT2 receptors.

    abstract::We have investigated the possibility that there is a correlation between female sexual receptivity and CNS serotonergic activity. In ovariectomized rats primed with a submaximal steroid regime of 2 micrograms oestradiol benzoate (OB) plus 0.2 mg progesterone (P), so that only a proportion were receptive, the 5-hydroxy...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91575-6

    authors: Wilson CA,Hunter AJ

    更新日期:1985-05-06 00:00:00

  • Are the dorsal noradrenergic bundle projections from the locus coeruleus important for neocortical or hippocampal activation?

    abstract::Three different methods were used to examine the importance of the dorsal noradrenergic bundle projections from the locus coeruleus (LC) in activation of the neocortex and hippocampus in freely moving rats. (1) After cerebral norepinephrine (NE) was depleted by systemic neonatal injections of 6-hydroxydopamine (6-OHDA...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(77)90785-5

    authors: Robinson TE,Vanderwolf CH,Pappas BA

    更新日期:1977-12-09 00:00:00

  • Calcium/calmodulin-dependent protein kinase II and protein phosphatase 2B (calcineurin) immunoreactivity in the rat hippocampus long after ischemia.

    abstract::Calcium/calmodulin-dependent protein kinase II (kinase II) and protein phosphatase 2B (calcineurin) immunoreactivity in the rat hippocampus was studied 100 days after ischemic damage to hippocampal CA1 pyramidal neurons. One-hundred days after ischemia, only a few CA1 pyramidal neurons survived and they exhibited enha...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00382-z

    authors: Onodera H,Yamasaki Y,Kogure K,Miyamoto E

    更新日期:1995-06-26 00:00:00

  • Increased number of unmyelinated axons in optic nerves of adult mice deficient in the myelin-associated glycoprotein (MAG).

    abstract::We have recently demonstrated that the formation of myelin sheaths in the optic nerve of young postnatal mice deficient in the myelin-associated glycoprotein (MAG) is retarded when compared to age-matched wild-type mice. In the present study, we analyzed whether impaired myelination of retinal ganglion cell axons is d...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00484-8

    authors: Bartsch S,Montag D,Schachner M,Bartsch U

    更新日期:1997-07-11 00:00:00

  • Spatiotemporal brain signal associated with high and low levels of proactive motor response inhibition.

    abstract::Proactive motor response inhibition is used to strategically restrain actions in preparation for stopping. In this study, we first examined the event related potential (ERP) elicited by low and high level of proactive response inhibition, as assessed by the stop-signal task. Corroborating previous studies, we found an...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2020.147064

    authors: Brevers D,Cheron G,Dahman T,Petieau M,Palmero-Soler E,Foucart J,Verbanck P,Cebolla AM

    更新日期:2020-11-15 00:00:00

  • Dexmedetomidine inhibits apoptosis of astrocytes induced by oxygen-glucose deprivation via targeting JAK/STAT3 signal pathway.

    abstract:OBJECTIVE:There is an increasing interest concerning the contribution of astrocytes to the intrinsic bioremediation of ischemic brain injury. The aim of this work was to disclose the effects and mechanism of dexmedetomidine (DEX) on the apoptosis of astrocytes under oxygen glucose deprivation (OGD) condition. METHODS:...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2020.147141

    authors: Feng P,Zhang A,Su M,Cai H,Wang X,Zhang Y

    更新日期:2021-01-01 00:00:00

  • Functional significance of projection from the cerebellar nuclei to the motor cortex in the cat.

    abstract::The functional organization of projections from the cerebellar subcortical nuclei to the motor cortex through the nucleus ventralis lateralis (VL) of the thalamus was studied using tungsten microelectrodes for stimulation and recordings in acute and chronic cats. The following results were obtained. (1) Microstimulati...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(75)90510-7

    authors: Asanuma H,Hunsperger RW

    更新日期:1975-11-07 00:00:00

  • The distribution of somatostatin-immunoreactive neurons in the visual cortex of adult rabbits and during postnatal development.

    abstract::In the adult rabbit, the somatostatin-immunoreactive neurons are seen in all visual cortical layers, with the majority of them being found in layers II-III, V and VI. During postnatal development, we can see labeled cells in layer VI at birth and in layers V and VI on the 3rd day. The labeled cells are seen in layers ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91456-8

    authors: Ramón y Cajal-Agüeras S,Contamina P,Parra P,Martinez-Millán L,De Carlos JA,Ramo C

    更新日期:1985-12-16 00:00:00

  • Diethyldithiocarbamate and dithizone augment the toxicity of kainic acid.

    abstract::Male Fischer-344 rats were injected i.p. with diethyldithiocarbamate or dithizone 15 min after kainic acid (KA), s.c. Diethyldithiocarbamate and dithizone reduced both the number of wet dog shakes and the latency to onset of seizures induced by KA. Moreover, they increased the severity of seizures. These compounds may...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91273-j

    authors: Mitchell CL,Barnes MI,Grimes LM

    更新日期:1990-01-08 00:00:00

  • Modulation of saccadic intrusions by exogenous and endogenous attention.

    abstract::Primary gaze fixation in healthy individuals is frequently interrupted by microsaccades and saccadic intrusions (SI). The neural systems responsible for the control of attention and eye movements are believed to overlap and in line with this, the behaviour of microsaccades appears to be affected by exogenous and endog...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.01.047

    authors: Gowen E,Abadi RV,Poliakoff E,Hansen PC,Miall RC

    更新日期:2007-04-13 00:00:00

  • Enhanced analgesic potency and reduced tolerance of morphine in 129/SvEv mice: evidence for a deficiency in GM1 ganglioside-regulated excitatory opioid receptor functions.

    abstract::10-fold higher doses in SW mice. Furthermore, cotreatment of 129/SvEv mice with morphine plus a low dose of naltrexone (ca. 0.1 microgram/kg) that markedly enhances and prolongs morphine's antinociceptive effects in SW mice did not enhance, and often attenuated6 h. The marked GM1-induced attenuation of morphine's anti...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)02446-4

    authors: Crain SM,Shen K

    更新日期:2000-02-21 00:00:00

  • Expression of functional receptors and transmitter enzymes in cultured Muller cells.

    abstract::Glia represents the most numerous group of nervous system cells and CNS development and function depend on glial cells. We developed a purified Muller glia culture to investigate the expression of several neurotransmitter markers on these cells, such as dopaminergic, cholinergic, GABAergic and peptidergic receptors or...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.01.031

    authors: Kubrusly RC,da Cunha MC,Reis RA,Soares H,Ventura AL,Kurtenbach E,de Mello MC,de Mello FG

    更新日期:2005-03-21 00:00:00

  • Neuronal responses to motion and apparent motion in the optic tectum of chickens.

    abstract::The ability to detect moving objects is crucial for survival and is a basic capability in the animal kingdom. In the optic tectum, a major center of the visual pathway of birds, neurons have been found that seem to be perfectly suited to encode motion. These cells, located in the stratum griseum centrale, receive a di...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2016.01.022

    authors: Verhaal J,Luksch H

    更新日期:2016-03-15 00:00:00