Abstract:
:Proactive motor response inhibition is used to strategically restrain actions in preparation for stopping. In this study, we first examined the event related potential (ERP) elicited by low and high level of proactive response inhibition, as assessed by the stop-signal task. Corroborating previous studies, we found an increased amplitude of the contingent negative variation (CNV) in the high level of proactive inhibition. As the main goal of the present study, swLORETA was used to determine the neural generators characterising CNV differences between low and high levels of proactive inhibition. Results showed that the higher level of proactive inhibition involved numerous generators, including within the middle and medial frontal gyrus. Importantly, we observed that the lower level of proactive inhibition also involved a specific neural generator, within the frontopolar cortex. Altogether, present findings identified the specific brain sources of ERP signals involved in the later phase of motor preparation under low or high levels of proactive motor response inhibition.
journal_name
Brain Resjournal_title
Brain researchauthors
Brevers D,Cheron G,Dahman T,Petieau M,Palmero-Soler E,Foucart J,Verbanck P,Cebolla AMdoi
10.1016/j.brainres.2020.147064subject
Has Abstractpub_date
2020-11-15 00:00:00pages
147064eissn
0006-8993issn
1872-6240pii
S0006-8993(20)30422-4journal_volume
1747pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The blockade of the lateral parabrachial nucleus (LPBN) with GABA(A) receptor agonist muscimol induces robust hypertonic NaCl and water intake by rats. In the present study we investigated the effects of previous injections of losartan (AT(1) angiotensin receptor antagonist) into the LPBN on 0.3M NaCl and water intake...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.06.004
更新日期:2011-07-27 00:00:00
abstract::Febrile seizure (FS) remains the most common childhood neurological emergency. Although many studies have been done, controversy exists as to whether these seizures are associated with a significant risk for cognitive impairment. The aim of our study is to check whether there is a spatial learning and memory deficit i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.02.026
更新日期:2014-04-04 00:00:00
abstract::We previously reported that abdominal surgery induces Fos expression in specific hypothalamic and medullary nuclei and also causes gastric stasis. The gastric ileus is reduced by systemic capsaicin and abolished by central injection of corticotropin-releasing factor (CRF) antagonist. We studied the influence of system...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(96)01281-4
更新日期:1997-02-14 00:00:00
abstract::The development of hypertension in spontaneously hypertensive rats (SHR) and hyperactive voiding in rats with urethral obstruction are characterized by abnormal smooth muscle growth, increased tissue levels of nerve growth factor (NGF) and altered patterns of innervation. The present study was undertaken to determine ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00061-4
更新日期:1998-04-20 00:00:00
abstract::In vivo microdialysis techniques were used to examine the effects of estrogen on potassium-stimulated acetylcholine release in the hippocampus and overlying cortex of adult, ovariectomized rats. Estrogen treatment resulted in a significant increase in the percent change in acetylcholine release induced by potassium re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(96)01375-3
更新日期:1997-02-21 00:00:00
abstract::Apoptosis has been shown to be induced by some pathological stimuli. MPP+ is a neurotoxin and an inducer of parkinsonism. When SH-SY5Y cells, human neuroblastoma cell line, were treated with MPP+, cell death estimated by lactate dehydrogenase (LDH) leakage assay occurred. The cell death was associated with the DNA fra...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01120-x
更新日期:1995-12-18 00:00:00
abstract::Electrical and pharmacological properties of currents induced by compounds having affinities for putative sigma receptors were investigated with NCB20 cells by use of the whole-cell patch-clamp technique. Antipsychotics and naloxone induced inward currents with a decrease in membrane conductance at a holding potential...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91232-7
更新日期:1994-02-21 00:00:00
abstract::We investigated the effect of losartan, a nonpeptide angiotensin II (Ang II)-type 1 (AT1) receptor antagonist, on the responses evoked by Ang II and L-glutamate (L-Glu) in the rostral ventrolateral medulla (RVLM). Adult spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats were anesthetized with halothane ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91344-7
更新日期:1994-12-05 00:00:00
abstract::We investigated the effects of neonatal optic nerve transection on cortical acetylcholinesterase (AChE) activity in hooded rats during postnatal development and following behavioral manipulation after weaning. AChE reaction product was quantified on digitized images of histochemically stained sections in layer IV of p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.12.080
更新日期:2007-03-30 00:00:00
abstract::The present study describes the time course of recovery in the fast axonal transport of 3H-labeled proteins in the nerve and the electrophysiological parameters in the extensor muscle of rats after single subperineural injection of batrachotoxin (BTX) (9.3 x 10(-12) mol) into the peroneal nerve. The fast axonal transp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90322-x
更新日期:1981-11-23 00:00:00
abstract::The effects of forced swimming for 30 min on extracellular 5-hydroxytryptamine (5-HT) levels were examined in five brain regions in rats using in vivo microdialysis. A single dialysis probe was implanted under surgical anesthesia into either the striatum, ventral hippocampus, frontal cortex, amygdala, or lateral septu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00349-u
更新日期:1995-06-05 00:00:00
abstract::The anesthetic-sedative barbiturate pentobarbital (PB) and the anticonvulsant barbiturate phenobarbital (PhB) were applied to mammalian spinal cord neurons in primary dissociated cell culture to assess their effects on: (1) postsynaptic GABA-responses; (2) paroxysmal activity produced by the convulsant bicuculline; (3...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)91179-3
更新日期:1981-03-23 00:00:00
abstract::[3H]Paroxetine binding to human brain tissue was characterized. Competition studies in the putamen and frontal cortex revealed single-site binding models for binding sensitive to 5-hydroxytryptamine (5-HT) (Ki 1-3 microM) and citalopram (Ki 0.6 nM), which displaced the same amount of binding. However, desipramine, nor...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90511-8
更新日期:1989-05-08 00:00:00
abstract::We investigated the effects of collagen II-induced arthritis on two cerebrospinal fluid (CSF) enzymes converting dynorphin A and substance P (SP), namely dynorphin-converting enzyme (DCE) and substance P endopeptidase (SPE). The products generated by these enzymes are the bioactive fragments Leu-enkephalin-Arg6 and su...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90718-o
更新日期:1992-05-29 00:00:00
abstract::Extracellular levels of acetylcholine (ACh) were measured in the central nucleus of the amygdala using microdialysis in 20-min intervals before, during, and after 1 h feeding in food-deprived rats. The results were compared to the effects of peripheral injections of glucose or 'low' (200 mU) and 'high' (1 U) doses of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)01291-2
更新日期:1998-02-23 00:00:00
abstract::Many of our everyday actions are only appropriate in certain situations and selecting the appropriate behavior requires that we use current context and previous experience to guide our decisions. The current study examined hippocampal functional connectivity with prefrontal and striatal regions during a task that requ...
journal_title:Brain research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brainres.2011.09.038
更新日期:2011-11-14 00:00:00
abstract::Antibodies were raised in rabbits against the neuropeptide N-acetyl-L-aspartyl-L-glutamate (NAAG) coupled to bovine serum albumin via a carbodiimide linkage. One of these rabbit antisera, which preferentially recognizes coupled NAAG-like immunoreactivity (LIR), has been previously used to immunocytochemically localize...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0169-328x(88)90045-9
更新日期:1988-06-01 00:00:00
abstract::[d-Ala(2)-d-Leu(5)]-Enkephalin (DADLE) has shown promising results in protecting neurons from damages. However, the mechanism for this protection is still under investigation. The current study was carried out to test the hypothesis that DADLE may regulate cellular transcription in neurons. SH-SY5Y cells and primary c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.04.007
更新日期:2014-05-27 00:00:00
abstract::In decerebrate rats, the responses of tilt-sensitive neurons in the lateral and descending vestibular nuclei were studied during constant velocity 10 degrees off-vertical axis rotations (OVAR) in the clockwise (VW) and counterclockwise (CCW) directions. Seventy three otolith-related units showed a sinusoidal position-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00687-l
更新日期:1995-09-25 00:00:00
abstract::Following injection of the acylating reagent N-succinimidyl [3H]propionate into the optic nerve of goldfish, labeled protein appeared in the ipsilateral retina and contralateral tectum in a time-dependent manner. Autoradiography indicated the presence of the labeled material in the neuroplasm of the retinal ganglion c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)91251-9
更新日期:1983-01-24 00:00:00
abstract::Experimental studies and clinical observations show that spinal cord lesions are greatly enlarged by a process called secondary cell death. A detailed understanding of the molecular and cellular processes underlying these events is still lacking. In clinical studies using methylprednisolone in spinal cord injured pati...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01410-j
更新日期:1995-02-20 00:00:00
abstract::In anaesthetized, spontaneously breathing cats and dogs, extracellular recordings were made of the spontaneous activities of 28 single neurones with cardiac rhythm. It was confirmed by histological examination that the neurones were situated in the mediodorsal portion of the nucleus of the solitary tract. Different di...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90049-x
更新日期:1977-09-09 00:00:00
abstract::Explosive running is a reliable initial component of audiogenic seizures (AS) induced by acoustic stimulation in genetically prone rodents. This profound locomotor activation is usually considered as a convulsive manifestation of AS although some studies attribute running to a panic-like response. Increase in central ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.02.017
更新日期:2007-05-07 00:00:00
abstract::Insular cortex (INS) plays a critical role in pain processing and shows sex differences in functional activation during noxious visceral stimulation. Less is known regarding functional interactions within the INS and between this structure and other parts of the brain. Cerebral blood flow mapping was performed using [...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.04.005
更新日期:2019-08-15 00:00:00
abstract::After glucocorticoid stimulation, glucocorticoid receptors (GRs) are translocated to the nucleus to modulate transcription of glucocorticoid target genes. The subcellular distribution and trafficking of GR in cultured cells has been studied quite intensively using several techniques. However, the intracellular localiz...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.03.052
更新日期:2010-05-17 00:00:00
abstract::Neuronal degeneration was detected in the tenia tecta and other regions of the anterior limbic system of male weanling rats 3 days after four doses of 5 mg/kg d-amphetamine (4 x 5 mg/kg AMPH) when seizures occurred during AMPH exposure. Neurodegeneration in the parietal cortex, loss of tyrosine hydroxylase immunoreact...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02925-5
更新日期:2000-12-08 00:00:00
abstract::When nomifensine is employed to inhibit neuronal uptake, exposure to dopamine (DA) (0.1-0.3 microM) or apomorphine (0.01-0.1 microM) inhibited, in a concentration-dependent manner, the electrically evoked release of [3H]dopamine from slices of the rabbit caudate nucleus. Apomorphine inhibited transmitter release indep...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91605-1
更新日期:1985-06-24 00:00:00
abstract::Rats with unilateral 6-hydroxydopamine lesions of the substantia nigra became briefly sedated and hypothermic after the acute injection of nicotine s.c. (0.4 or 0.8 mg/kg free base). When nicotine was repeated 5 days per week there was rapid tolerance for the sedation and slower tolerance for the hypothermia and the l...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91114-0
更新日期:1987-03-31 00:00:00
abstract::Five pairs of neurosecretory cells in the subesophageal ganglion of the silkmoth Bombyx mori discharge action potentials in (near) synchrony to release a pheromone biosynthesis-activating neuropeptide (PBAN). Waveforms of compound action potentials recorded extracellularly from axonal tracts were analyzed to determine...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)03349-2
更新日期:2002-03-08 00:00:00
abstract::Receptors for alpha-bungarotoxin are found on the surface of parasympathetic neurons in the frog cardiac ganglion by light microscopic autoradiography. Competition studies suggest that these receptors are cholinergic and indicate that they are also recognized by neuronal bungarotoxin (kappa-bungarotoxin). These recept...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00250-t
更新日期:1995-05-22 00:00:00