Schwann cells can misdirect regrowing neuronal processes.

abstract：:Monoclonal antibody N1 reacts by indirect immunofluorescence with the cell surface of tetanus toxin-positive neurons from early postnatal mouse cerebellum. In freshly trypsinized single cell suspensions from early postnatal mouse cerebellum, 5-10% of all viable cells express N1 antigen on their surface. After 3-24 h o...

journal_title：Brain research

authors： Schnitzer J,Kim SU,Schachner M

更新日期：1984-07-01 00:00:00

abstract：:Long-term potentiation (LTP) has a memory-like consolidation period during which it becomes progressively stabilized. However, it is unknown how the consolidation is achieved. The present study demonstrates that nicotine reverses stabilized LTP in the hippocampal CA1 region, providing the first evidence that consolida...

journal_title：Brain research

authors： Guan X,Nakauchi S,Sumikawa K

更新日期：2006-03-17 00:00:00

abstract：:Highly specific antibodies to dynorphin A(1-13), infused into the lateral ventricle, elevated brain stimulation threshold for eliciting feeding behavior. Antibodies to beta-endorphin had little or no effect. Temporal analysis of the anorectic action indicated a striking similarity to the effect of systemically adminis...

journal_title：Brain research

authors： Carr KD,Bak TH,Gioannini TL,Simon EJ

更新日期：1987-10-06 00:00:00

abstract：:Animal models of cerebral infarction are crucial to understanding the mechanisms of neuronal survival following ischemic brain injury and to the development of therapeutic interventions for victims of all types of stroke. Rodents have been used extensively in such research. One rodent model of stroke utilizes either p...

journal_title：Brain research

authors： Duckworth EA,Butler TL,De Mesquita D,Collier SN,Collier L,Pennypacker KR

更新日期：2005-04-25 00:00:00

abstract：:The cloned 5-HT3 receptor from NCB-20 neuroblastoma cells was expressed in Xenopus oocytes. In these oocytes, 5-HT, the selective 5-HT3 receptor agonists, 2-methyl-5-HT and m-chlorophenylbiguanide activated an inward current which was sensitive to the specific 5-HT3 receptor antagonist LY278584. Cocaine (0.1 to 10 mic...

journal_title：Brain research

authors： Fan P,Oz M,Zhang L,Weight FF

更新日期：1995-03-06 00:00:00

abstract：:Chick embryos ranging in age from 4.0 to 18 days of incubation and 1-2-day-old hatchlings received injections of HRP solutions directly into the leg musculature. After survival periods of from 5 to 25 h motoneurons and cells in the spinal sensory ganglia were found to be stained with the HRP reaction product. It was f...

journal_title：Brain research

authors： Oppenheim RW,Heaton MB

更新日期：1975-11-14 00:00:00

abstract：:It has been confirmed that gabapentin (GBP) induced a inhibition of the voltage-gated persistent sodium current in chronically compressed dorsal root ganglion (DRG) neurons. The persistent sodium current is found in excitable DRG neurons of painful diabetic neuropathy (PDN) rats where it is mediated by tetrodotoxin (T...

journal_title：Brain research

authors： Zhang JL,Yang JP,Zhang JR,Li RQ,Wang J,Jan JJ,Zhuang Q

更新日期：2013-02-01 00:00:00

abstract：:The effect of high concentrations of L-ascorbic acid on the in vivo and in vitro growth of human neuroblastoma has been investigated. Directly implemented into cell culture it decreased the DNA, RNA and protein synthesis, and mitosis of neuroblastoma cells, without affecting normal neuronal cells. In vivo treatment of...

journal_title：Brain research

authors： Pavelić K

更新日期：1985-09-09 00:00:00

abstract：:Monkeys made hemiparkinsonian by infusion of a solution of MPTP into one carotid artery appeared to ignore food presented from the contralateral side. Initial observations suggested neglect of visual stimuli presented as fruit treats by automated delivery system in the half-field contralateral to MPTP treatment. Furth...

journal_title：Brain research

authors： Bankiewicz KS,Oldfield EH,Plunkett RJ,Schuette WH,Cogan DG,Hogan N,Zuddas A,Kopin IJ

更新日期：1991-02-08 00:00:00

abstract：:Degeneration of noradrenergic neurons in the locus coeruleus (LC) and dysfunction of the prefrontal cortex were regarded as playing a specific role in the occurrence of non-motor symptoms in Parkinson's disease. The present study examined the spontaneous firing rate and firing pattern of medial prefrontal cortex (mPFC...

journal_title：Brain research

authors： Wang Y,Zhang QJ,Liu J,Ali U,Gui ZH,Hui YP,Wang T,Chen L,Li Q

更新日期：2010-04-09 00:00:00

abstract：:Rats were administered haloperidol (0.5 mg/kg/day) for 21 days. Twenty percent of locus coeruleus (LC) neurons recorded were not spontaneously active, while no such neuron was observed in control animals. A further 22% of neurons (spontaneously active) had rates greater than 2 standard deviations from the mean of LC c...

journal_title：Brain research

authors： Dinan TG,Aston-Jones G

更新日期：1985-01-28 00:00:00

abstract：:Male rats were treated with barbital in their drinking fluid for about 40 weeks (daily dose 200 mg/kg). The treatment was stopped on day 0 and the number of muscarinic binding sites was measured in 3 brain parts (striatum; cortex and hippocampus; medulla oblongata and midbrain) during the abstinence with labeled quinu...

journal_title：Brain research

authors： Nordberg A,Wahlström G

更新日期：1982-08-19 00:00:00

abstract：:Increased neurogenesis by promoting proliferation of neural precursor cells in the adult dentate gyrus might be beneficial for the treatment of psychiatric disorders. Results demonstrate that bFGF is necessary for the proliferation of neural precursor cells and that the glycogen synthase kinase-3β (GSK-3β) and β-caten...

journal_title：Brain research

authors： Boku S,Nakagawa S,Toda H,Kato A,Takamura N,Omiya Y,Inoue T,Koyama T

更新日期：2013-01-25 00:00:00

abstract：:It has been shown that glucagon like peptide-1 (GLP-1) acts on the central nervous system (CNS), in addition to its peripheral actions. Central administration of glucagon like peptide-1 (GLP-1) delays liquid gastric emptying via non-adrenergic, non-cholinergic neurons in rats. However, it remains unclear how central G...

journal_title：Brain research

authors： Nakade Y,Tsukamoto K,Pappas TN,Takahashi T

更新日期：2006-09-21 00:00:00

abstract：:Amyloid precursor protein (APP) is a ubiquitously expressed membrane spanning glycoprotein which is endoproteolytically processed to Abeta, a 39-43 amino acid peptide that is the main component of senile plaques in Alzheimer Disease (AD). APP is a member of a highly conserved gene family, including Amyloid Precursor-L...

journal_title：Brain research

authors： McNamara MJ,Ruff CT,Wasco W,Tanzi RE,Thinakaran G,Hyman BT

更新日期：1998-08-31 00:00:00

abstract：:Microinjection of apomorphine into the ventral tegmental area (VTA) of male rats was previously shown to delay the onset of copulation and slow its rate, presumably by stimulating impulse-regulating autoreceptors on cell bodies of the A10 mesocorticolimbic dopamine tract. Such stimulation would be expected to slow the...

journal_title：Brain research

authors： Hull EM,Weber MS,Eaton RC,Dua R,Markowski VP,Lumley L,Moses J

更新日期：1991-07-19 00:00:00

abstract：:We have previously reported that intracerebroventricular injection of prostaglandin E2 (PGE2) induces hyperthermia possibly through EP1 receptors in the rat. In the present study, to determine the sites in the brain where PGE2 induces hyperthermia through EP1 receptors, we microinjected an EP1 receptor agonist, 17-phe...

journal_title：Brain research

authors： Oka K,Oka T,Hori T

更新日期：1997-08-29 00:00:00

abstract：:The cholinergic neurotoxin, AF64A-picrylsulfonate, was unilaterally infused into the dorsal hippocampus of Wistar rats (2 nmol/2 microliters/4 min; A 6.2, Ls 1.5, H 6.5, Paxinos and Watson). After 19 days the for immunohistochemical staining of choline acetyltransferase (ChAT). Morphometry and counting of ChAT-immunor...

journal_title：Brain research

authors： Tonnaer JA,Lammers AJ,Wieringa JH,Steinbusch HW

更新日期：1986-04-02 00:00:00

abstract：:The specific benzodiazepine antagonist, Ro14-7437, in nanomolar concentrations, caused depolarization, increased spontaneous spiking, and conductance decrease when applied to CA1 cells in vitro. These effects were resistant to intracellularly injected Cl- ions or synaptic blockade by TTX, were prevented in Ca2+-free m...

journal_title：Brain research

authors： Carlen PL,Gurevich N,Polc P

更新日期：1983-07-18 00:00:00

abstract：:Flexion movements induced by cortical stimulation and the associated postural adjustments in bilaterally pyramidotomised cats have been studied by means of an apparatus which measures separately the changes of force under each limb in the upright position of the animal. The results show: (1) The general motor behaviou...

journal_title：Brain research

authors： Nieoullon A,Gahéry Y

更新日期：1978-06-23 00:00:00

abstract：:An isoindolin-1-one derivate, JM-1232(-), was recently developed as a sedative and hypnotic agent with a strong affinity for the central benzodiazepine binding site of gamma-aminobutyric acid(A) (GABA(A)) receptors. The purpose of this study was to examine the effects of JM-1232(-) on the cardiovascular and sympatheti...

journal_title：Brain research

authors： Shirasaka T,Kunitake T,Tsuneyoshi I

更新日期：2009-12-01 00:00:00

abstract：:The purpose of this study was to determine whether treatment with high-dose human serum albumin (HSA) would offer protection in a model of high-grade transient forebrain ischemia. Twenty-six fasted Wistar rats underwent bilateral common carotid artery occlusion and severe hypotension (50 mmHg) for 10 min. The agent (2...

journal_title：Brain research

authors： Belayev L,Saul I,Huh PW,Finotti N,Zhao W,Busto R,Ginsberg MD

更新日期：1999-10-16 00:00:00

abstract：:Opioid antagonists block the positive hedonic response to food taste and are potent inhibitors of palatability-driven feeding. However, the specific brain regions within which opioid peptide secretion contributes to the maintenance of palatability-driven feeding have not been clearly established. In the present study,...

journal_title：Brain research

authors： Park TH,Carr KD

更新日期：1998-09-14 00:00:00

abstract：:The anatomical localization of nociceptin receptors was examined by in vitro quantitative autoradiography techniques in rat spinal cord sections by using [(125)I-Tyr(14)]nociceptin. [(125)I-Tyr(14)]nociceptin appeared to interact with a single class of binding sites (K(D)=0.1 nM) present in the grey matter in all lami...

journal_title：Brain research

authors： Gouardères C,Tafani JA,Meunier JC,Jhamandas K,Zajac JM

更新日期：1999-08-14 00:00:00

abstract：:The present study examines age-related changes in the subcellular localization of cathepsin B (cath B) and cathepsin D (cath D), as well as morphological features of the cathepsin-immunoreactive (ir) neurons in rat cerebral cortex. Sprague-Dawley rats were studied at 3 and 26 months. By immunoelectron microscopy cath ...

journal_title：Brain research

authors： Jung H,Lee EY,Lee SI

更新日期：1999-10-09 00:00:00

abstract：:Single-electrode depth profiles of the hippocampal EEG were made in urethane-anesthetized rats and rats trained in an alternating running/drinking task. Current source density (CSD) was computed from the voltage as a function of depth. A problem inherent to AC-coupled profiles was eliminated by incorporating sustained...

journal_title：Brain research

authors： Brankack J,Stewart M,Fox SE

更新日期：1993-07-02 00:00:00

abstract：:The aim of this work was to characterize the interaction of the Na+-channel toxin, purified from venom of the scorpion Leiurus quinquestriatus, with microtubule proteins in vitro. The toxin enhanced microtubule assembly, causing the formation of microtubule 'bundles'. It interacted with the Na+-channel 270 kDa subunit...

journal_title：Brain research

authors： Hargreaves AJ,Montejo de Garcini E,Avila J

更新日期：1986-07-01 00:00:00

abstract：:Sterol regulatory element binding protein (SREBP)-1 is a membrane-bound transcription factor that regulates the expression of several genes involved in cellular fatty acid synthesis in the peripheral tissues, including liver. Although SREBP-1 is expressed in brain, little is known about its function. The aim of the pr...

journal_title：Brain research

authors： Okamoto K,Kakuma T,Fukuchi S,Masaki T,Sakata T,Yoshimatsu H

更新日期：2006-04-07 00:00:00

abstract：:Different groups of rats received three injections of either D-amphetamine (2.5 micrograms/0.5 microliters/side) or saline into the ventral tegmental area (VTA), one injection every third day. Two weeks following the last injection, dopamine (DA) neurotransmission in the nucleus accumbens (N. Acc.) was assessed with i...

journal_title：Brain research

authors： Vezina P

更新日期：1993-03-12 00:00:00

abstract：:Cerebellar explants derived from neonatal mice were exposed to cytosine arabinoside, an inhibitor of DNA synthesis. Following such exposure, the cortical regions of the explants contained numerous closely packed large neurons with few intervening elements and without lamination. The surviving large cortical neurons in...

journal_title：Brain research

authors： Seil FJ,Leiman AL,Woodward WR

更新日期：1980-03-31 00:00:00