Electrical stimulation of the dorsal hippocampus caused a long lasting inhibition of ACTH and adrenocortical responses to photic stimuli in freely moving rats.

abstract：:The role of nicotinic cholinergic transmission in cold stress-induced alterations in rat adrenomedullary tyrosine hydroxylase (TH) mRNA was investigated by RNA dot-blot hybridization, using a cloned TH cDNA probe. Chlorisondamine, a ganglionic blocking agent, greatly attenuated the induction of TH mRNA levels caused b...

journal_title：Brain research

authors： Stachowiak M,Stricker EM,Zigmond MJ,Kaplan BB

更新日期：1988-04-01 00:00:00

abstract：:The core neuropsychological processes underlying post-traumatic stress disorder (PTSD) have yet to be elucidated, and the association between anatomical and functional deficits in PTSD remains largely unknown. The aim of our study was to investigate the alterations in cortical thickness and amplitude of low-frequency ...

journal_title：Brain research

authors： Bing X,Ming-Guo Q,Ye Z,Jing-Na Z,Min L,Han C,Yu Z,Jia-Jia Z,Jian W,Wei C,Han-Jian D,Shao-Xiang Z

更新日期：2013-01-15 00:00:00

abstract：:We have previously found that crocin (crocetin di-gentiobiose ester) antagonizes the inhibitory effect of ethanol on long-term potentiation in the rat hippocampus in vivo and in vitro. To explore mechanisms underlying the antagonism of crocin against ethanol, we investigated the effects of ethanol and crocin on synapt...

journal_title：Brain research

authors： Abe K,Sugiura M,Shoyama Y,Saito H

更新日期：1998-03-16 00:00:00

abstract：:The hypothesis according to which BoTx and TeTx block neuromuscular transmission by impairing Ca2+ influx was tested by recording presynaptic membrane currents at motor endplates of the mouse by means of external electrodes. The use of K-channel blockers allowed us to observe inward Ca current which was unaffected by ...

journal_title：Brain research

authors： Dreyer F,Mallart A,Brigant JL

更新日期：1983-07-04 00:00:00

abstract：:Repeated sensory exposure through frequent consumption of certain foods leads to changes in the processing of sensory cues. We investigated the influence of frequent minty chewing gum consumption on the neurobehavioral processing of intranasal trigeminal and olfactory stimuli. fMRI responses to a trigeminal minty odor...

journal_title：Brain research

authors： Han P,Penzler M,Jonathan W,Hummel T

更新日期：2020-03-01 00:00:00

abstract：:Microinfusion of the metabolically stable substance P (SP) agonist, [pGlu5,MePhe8,Sar9]-SP5-11 (DiMe-C7), into the ventral tegmental area (VTA) of rat brain increased levels of the dopamine (DA) metabolite dihydroxyphenylacetic acid in the prefrontal cortex (+ 120%) and nucleus accumbens (+30%) but not in other region...

journal_title：Brain research

authors： Elliott PJ,Alpert JE,Bannon MJ,Iversen SD

更新日期：1986-01-15 00:00:00

abstract：:Glial-cell-line-derived neurotrophic factor (GDNF), neurturin (NRTN), artemin (ARTN) and persephin (PSPN), known as the GDNF family ligands (GFLs), influence the development, survival and differentiation of cultured dopaminergic neurons from ventral mesencephalon (VM). Detailed knowledge about the effects of GFLs on o...

journal_title：Brain research

authors： Ducray A,Krebs SH,Schaller B,Seiler RW,Meyer M,Widmer HR

更新日期：2006-01-19 00:00:00

abstract：:The first phase of this study involves injecting a different fluorescent retrograde axonal tracer into the subthalamic nucleus, the substantia nigra, and the mesopontine tegmentum. Multiple labeled cells are found within the caudal third of the globus pallidus. The entopeduncular nucleus and adjacent basal forebrain s...

journal_title：Brain research

authors： Schmued L,Phermsangngam P,Lee H,Thio S,Chen E,Truong P,Colton E,Fallon J

更新日期：1989-05-15 00:00:00

abstract：:A motor disorder similar to idiopathic Parkinson's Disease develops in rhesus monkeys after several daily repeated doses of N-methyl-4-phenyl, 1,2,3,6-tetrahydropyridine (MPTP). The concentrations of peptides derived from proenkephalin A, proenkephalin B, substance P and somatostatin were measured by specific radioimm...

journal_title：Brain research

authors： Zamir N,Skofitsch G,Bannon MJ,Helke CJ,Kopin IJ,Jacobowitz DM

更新日期：1984-11-26 00:00:00

abstract：:Electrophysiological studies suggest that an increase in excitatory amino acid release may occur in the locus coeruleus during opiate withdrawal. The present study examined directly by microdialysis in anesthetized rats the effect of naltrexone-precipitated opiate withdrawal on the efflux of excitatory amino acids in ...

journal_title：Brain research

authors： Aghajanian GK,Kogan JH,Moghaddam B

更新日期：1994-02-04 00:00:00

abstract：:We previously reported a model of acute cochlear energy failure using a mitochondrial toxin, 3-nitropropionic acid (3-NP), to study mechanisms of inner ear disorders such as inner ear ischemia. In this model, the main cause of hearing loss is apoptosis of fibrocytes in the cochlear lateral wall. Here, we analyzed the ...

journal_title：Brain research

authors： Mizutari K,Nakagawa S,Mutai H,Fujii M,Ogawa K,Matsunaga T

更新日期：2011-10-24 00:00:00

abstract：:Visual spatial orienting of attention towards exogenous cues has been one of the attentional functions considered to be spared in ADHD. Here we present a design in which 60 (30 ADHD) children, age: 10.9±1.4, were asked to covertly orient their attention to one or two (out of four) cued locations, and search for a targ...

journal_title：Brain research

authors： Ortega R,López V,Carrasco X,Anllo-Vento L,Aboitiz F

更新日期：2013-02-01 00:00:00

abstract：:Glutamate is a major neurotransmitter in the CNS. Its release activates NMDA and non-NMDA receptors on the postsynaptic membrane. NMDA receptor activation is shown to be important in physiological and pathological events. The modulatory sites on the NMDA receptor-channel ionophore complex are important in the regulati...

journal_title：Brain research

authors： Saybasili H

更新日期：1998-03-09 00:00:00

abstract：:We have examined the soma diameters and distribution of catecholaminergic (CA) cells in human retinae, by using an antibody to tyrosine hydroxylase (TH), the rate limiting enzyme in the production of catecholamines. TH-immunoreactivity was detected in two classes of cells (CA1 and CA2 cells). CA1 cells had relatively ...

journal_title：Brain research

authors： Mitrofanis J,Provis JM

更新日期：1990-09-10 00:00:00

abstract：:The effects of cocaine administration and withdrawal on D1 and D2 dopamine receptor number, affinity, and mRNA levels were examined in rats trained to self-administer cocaine for four weeks on a continuous reinforcement schedule. Two hours after the last infusion of cocaine there was a decrease in the number and agoni...

journal_title：Brain research

authors： Laurier LG,Corrigall WA,George SR

更新日期：1994-01-14 00:00:00

abstract：:Anticipation of an unavoidable painful stimulation, i.e. anticipation stress, induces analgesia. This analgesia may result from activation of the endogenous opioid peptide system as it is blocked by naloxone. The present paper characterizes the anticipation stress further by following the kinetics of the analgesia ris...

journal_title：Brain research

authors： Sumová A,Jakoubek B

更新日期：1989-12-04 00:00:00

abstract：:Single-electrode depth profiles of the hippocampal EEG were made in urethane-anesthetized rats and rats trained in an alternating running/drinking task. Current source density (CSD) was computed from the voltage as a function of depth. A problem inherent to AC-coupled profiles was eliminated by incorporating sustained...

journal_title：Brain research

authors： Brankack J,Stewart M,Fox SE

更新日期：1993-07-02 00:00:00

abstract：:Early brain injury (EBI) refers to the direct injury to the brain during the first 72 h after subarachnoid hemorrhage (SAH), which is one of the major causes for the poor clinical outcome after SAH. In this study, we investigated the effect and the related mechanism of Salvinorin A (SA), a selective kappa opioid recep...

journal_title：Brain research

authors： Sun J,Yang X,Zhang Y,Zhang W,Lu J,Hu Q,Liu R,Zhou C,Chen C

更新日期：2019-09-15 00:00:00

abstract：:The triggering of ectopic action potentials (APs) at axon terminals in a chronic epileptic cobalt focus was investigated in thalamocortical (TC) neurons of rats under urethane anesthesia. TC cells which were in register with an active epileptic aggregate discharged bursts of 2-11 APs. According to the rules of the col...

journal_title：Brain research

authors： Pinault D

更新日期：1992-03-27 00:00:00

abstract：:The pedunculopontine tegmental nucleus (PPT) has been implicated in the generation and/or maintenance of both active sleep (AS) and wakefulness (W). GABAergic neurons are present within this nucleus and recent studies have shown that these neurons are active during AS. In order to examine the role of mesopontine GABAe...

journal_title：Brain research

authors： Torterolo P,Morales FR,Chase MH

更新日期：2002-07-19 00:00:00

abstract：:The cell-mediated inflammatory component of experimental autoimmune encephalomyelitis (EAE) in mice is measured by the radioisotopic technique. Mice are challenged with autologous spinal cord homogenate in Freund's complete adjuvant and at various time intervals after such immunization given [125I]5-iodo-2'-deoxyuridi...

journal_title：Brain research

authors： Linthicum DS,Horvath L,Carnegie PR

更新日期：1979-10-05 00:00:00

abstract：:Extracellular recordings of action potentials were made from neurones antidromically identified as neurosecretory cells in the paraventricular and supraoptic nuclei of urethane-anesthetized female rats. Eighty-six neurones were examined for their responsiveness to 10 ng of angiotensin II (AII) injected into the third ...

journal_title：Brain research

authors： Akaishi T,Negoro H,Kobayasi S

更新日期：1980-04-28 00:00:00

abstract：:In the brain, nitric oxide (NO) has been identified as a messenger molecule and a mediator of excitatory amino acid-induced neurotoxicity. In this study, the effects of NO on serum-induced mitogenesis and cell proliferation of the cerebellar glial cells were assessed. NO-generating agent, S-nitroso-N-acetylpenicillami...

journal_title：Brain research

authors： Garg UC,Devi L,Turndorf H,Goldfrank LR,Bansinath M

更新日期：1992-10-02 00:00:00

abstract：:Activation of the immune system produces psychological and physiological effects, which resemble the characteristics of depression. The present study was designed to investigate further, in rats, the similarity between the behavioral effects of immune activation and a model of depression in animals. Reduction in the p...

journal_title：Brain research

authors： Yirmiya R

更新日期：1996-03-04 00:00:00

abstract：:Glutamate is an excitatory neurotransmitter implicated in the pathogenesis of psychiatric disorders. Glutamate results in the activation of an enzyme called glycogen synthase kinase-3 (GSK-3) acting through N-methyl-d-aspartate (NMDA) receptors. Impaired expression of GSK-3 affects behavior and neurochemicals level in...

journal_title：Brain research

authors： Walia V,Garg C,Garg M

更新日期：2019-02-01 00:00:00

abstract：:The monovalent lithium ion inhibits the enzyme myo-inositol-1-phosphatase at concentrations comparable to those which are useful in the treatment of manic depressive illness. However, dialyzed cortical homogenates from rats which have been fed diets containing lithium carbonate demonstrate increased myo-inositol-1-pho...

journal_title：Brain research

authors： Renshaw PF,Joseph NE,Leigh JS Jr

更新日期：1986-08-20 00:00:00

abstract：:We monitored biosynthetic activity of optic tract glia during regeneration of retinal ganglion cell axons in the goldfish and found that the greatest level of incorporated [3H]thymidine and [3H]leucine occurred in glia by 10-15 days after axotomy. During this period there was a marked increase in the number of oligode...

journal_title：Brain research

authors： Giulian D,Iwanij V,Stuckenbrok H

更新日期：1985-07-22 00:00:00

abstract：:The acute stroke phase is a critical time frame used to evaluate stroke severity, therapeutic options, and prognosis while also serving as a major tool for the development of diagnostics. To further understand stroke pathophysiology and to enhance the development of treatments, our group developed a translational pig ...

journal_title：Brain research

authors： Kaiser EE,Waters ES,Fagan MM,Scheulin KM,Platt SR,Jeon JH,Fang X,Kinder HA,Shin SK,Duberstein KJ,Park HJ,West FD

更新日期：2020-06-01 00:00:00

abstract：:We investigated the effects of a novel Na(+)/H(+) exchanger-1 (NHE-1) inhibitor KR-33028 on glutamate excitotoxicity in cultured neuron cells in vitro and cerebral infarct in vivo by comparing its potency with that of zoniporide, a well-known, highly potent NHE-1 inhibitor. KR-33028 inhibited NHE-1 activation in a con...

journal_title：Brain research

authors： Lee BK,Lee DH,Park S,Park SL,Yoon JS,Lee MG,Lee S,Yi KY,Yoo SE,Lee KH,Kim YS,Lee SH,Baik EJ,Moon CH,Jung YS

更新日期：2009-01-12 00:00:00

abstract：:It is suggested that altered neuroplasticity contributes to the pathophysiology of schizophrenia and antipsychotics may exhibit some of their therapeutic efficacies by improving neurogenesis and/or proliferation of neural progenitors. The aim of this study is to investigate whether chronic antipsychotics treatment aff...

journal_title：Brain research

authors： Chikama K,Yamada H,Tsukamoto T,Kajitani K,Nakabeppu Y,Uchimura N

更新日期：2017-12-01 00:00:00