Abstract：
:The taste reactivity test described in the preceding paper was used to begin determining the capacity of brain stem structures to execute and regulate ingestive behavior. Both chronic thalamic and chronic decerebrate rat preparations were examined repeatedly, and their gustatory mimetic responses compared through frame-by-frame videotape analysis with the responses of neurologically normal controls. In response to orally injected taste stimuli, chronic decerebrate rats executed the same mimetic response components, and very similar response sequences observed in intact rats. In contrast, all taste stimuli elicited a quinine-like rejection sequence from chronic thalamic rats. In thalamic rats mimetic responses associated with ingestion were completely absent. Based on the similarities in the ingestion and rejection responses of decerebrate and intact rats, it appears that discriminative responses to taste result from integrative mechanisms complete within, or caudal to, the midbrain. Since decerebrate rats have the capacity to execute both ingestion and rejection response sequences, neural mechanisms rostral to the midbrain in some way suppress ingestion and/or releaser ejection responses in the thalamic preparation.
journal_name
Brain Resjournal_title
Brain researchauthors
Grill HJ,Norgren Rdoi
10.1016/0006-8993(78)90569-3subject
Has Abstractpub_date
1978-03-24 00:00:00pages
281-97issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(78)90569-3journal_volume
143pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Histochemical and immunochemical techniques are used to locate 2',3'-cyclic nucleotide-3'-phosphohydrolase (2',3'-cNMP-3'ase) within cells of the vertebrate retina. A new histochemical method is described which links the hydrolysis of 2',3'-cNADP to the formation of a reduced, insoluble tetrazolium formazan. Photorece...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90335-9
更新日期：1983-04-18 00:00:00
abstract：:Previous studies in this laboratory have demonstrated that cholinergic receptors within the spinal cord play an important role in the expression of naloxone-precipitated withdrawal symptoms in the morphine-dependent rat. Related cardiovascular studies in non-dependent animals have demonstrated that this spinal choline...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00203-3
更新日期：1995-05-15 00:00:00
abstract：:The neurophysiological effects of a novel, orally active, competitive N-methyl-D-aspartate (NMDA) receptor antagonist (DL-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester), CGP 39551, on the high pressure neurological syndrome (HPNS) were investigated in the non-human primate Papio anubis. Six animals wer...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90817-7
更新日期：1993-09-17 00:00:00
abstract：:The resurgent Na(+) current (I(NaR)) is a component of neuronal voltage-dependent Na(+) currents that is activated by repolarization and is believed to result from an atypical path of Na(+)-channel recovery from inactivation. So far, I(NaR) has only been identified in a small number of central neuronal populations in ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.05.065
更新日期：2007-08-13 00:00:00
abstract：:The electroretinogram (ERG) of the dark-adapted goldfish was examined before and after intravitreal injection of DL-2-amino-4-phosphonobutyric acid (APB). APB abolished the b-wave and decreased absolute sensitivity of the remaining waveform, which was composed of a vitreal-negative component followed by a vitreal-posi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91194-3
更新日期：1989-03-20 00:00:00
abstract：:Visuomotor behavior and pattern discrimination were studied in a group of cats raised with one eye closed by eyelid suturing 7-10 days after birth. At the age of 8-10 months the animals were forced to use their deprived eye by reversal of eye closure (closing the normal eye and opening the deprived one). Visuomotor be...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90771-x
更新日期：1976-07-30 00:00:00
abstract：:The use of two different radioligands, [125I]Leu8, D-Tryp22,Tyr25-somatostatin-28 and the stable somatostatin octapeptide analog [125I]204-090, D-Phe-Cys[125I]Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), allowed to differentiate between two somatostatin receptor subpopulations in the human cortex. In homogenates, octapeptide somato...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90813-4
更新日期：1987-03-17 00:00:00
abstract：:Neonatal rat superior cervical ganglia were mechanically dissociated, and the sympathetic neurons grown in dispersed cell cultures. Intracellular microelectrodes were used to study the effects of tetraethylammonium (TEA+), a blocker of outward K+ currents, on the excitable properties of these neurons. Addition of TEA+...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91234-4
更新日期：1984-02-20 00:00:00
abstract：:NK1 receptor antagonists have been shown to act centrally and to produce a broad-spectrum anti-emetic action. To determine precisely the site of this action, we microinjected GR205171, an NK1 receptor antagonist, into the left medulla oblongata in decerebrate paralyzed dogs. The right medulla was transected 2.5 mm ros...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)01324-9
更新日期：1999-02-13 00:00:00
abstract：:Threohydroxyaspartate (THA)-induced glutamate excitotoxicity in organotypic culture of rat spinal cord is a well-known model of motor neuron degeneration. THA causes accumulation of synaptic glutamate and over stimulation of the postsynaptic receptor by inhibiting glutamate uptake. This model has also been used to ide...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.12.030
更新日期：2009-02-27 00:00:00
abstract：:We employed a highly sensitive combination method of retrograde tracing and immunohistochemistry to identify calcitonin gene-related peptide (CGRP)-containing fiber pathways in the rat from the ventrolateral part of the ventrolateral thalamic nucleus (vl-vl) and the caudal continuation to the insular cortex. Biotin-wh...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91211-9
更新日期：1985-09-30 00:00:00
abstract：:The presence and localization of synapsin I were investigated in the cat vestibular epithelium, using a rabbit anti-synapsin I antibody. The staining was performed by immunofluorescence or by a peroxidase-anti-peroxidase technique. A strong immunoreactivity was observed with both methods. It appeared as spherical patc...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91176-5
更新日期：1986-10-08 00:00:00
abstract：:Administration of aminooxyacetic acid, (an inhibitor of gamma-aminobutyric acid (GABA)-transaminase which enhances the hypothalamic GABA content) increased luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels in prepubertal rats (16 days of age), and decreased the levels of these pituitary hormones i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91508-x
更新日期：1991-11-01 00:00:00
abstract：:Altered expression of neurotrophins may contribute to the pathogenesis of schizophrenia. Several studies suggest sex steroid hormones may be involved in the regulation of brain-derived neurotrophic factor (BDNF) signaling, as well as the symptoms of schizophrenia. This study aimed to identify sex differences in BDNF-T...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.01.060
更新日期：2011-04-12 00:00:00
abstract：:The involvement of endogenous serotonergic pathways in the mediation of antinociception has been indicated by electrophysiological, pharmacological and behavioral experiments. However, manipulation of the indole pathway, either by lesioning of raphe nuclei or drug intervention, often produces disparate results. In par...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90883-3
更新日期：1987-11-24 00:00:00
abstract：:Immunohistochemical studies with an antiserum raised against tyrosine hydroxylase have allowed us to demonstrate a dense dopaminergic innervation of the globus pallidus in the squirrel monkey. This innervation derived mostly from two fascicles that detached themselves from the major ascending dopaminergic bundle arisi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90896-1
更新日期：1987-11-24 00:00:00
abstract：:The present study was designed to evaluate the sleep pattern of rats submitted to chronic stressors (restraint, electrical footshock, swimming and cold) applied to male rats. After 48 h-baseline recording, rats were submitted to 4 days of chronic stress, and electrocorticogram recordings were carried out continuously....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.08.021
更新日期：2005-10-26 00:00:00
abstract：:Manipulations of either discrete emotions (e.g. happiness) or affective dimensions (e.g. positivity) have a long tradition in emotion research, but interactive effects have never been studied, based on the assumption that the two underlying theories are incompatible. Recent theorizing suggests, however, that the human...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.03.045
更新日期：2014-05-20 00:00:00
abstract：:Reducing external calcium from 1.0 to 0.1 mM increased the flash sensitivity and the time-to-peak (tp) of linear responses of rod photoreceptors. The quantitative relation between flash sensitivity and tp was the same as during light adaptation. However, the calcium ionophore A23187 reduced sensitivity without affecti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90405-6
更新日期：1985-04-15 00:00:00
abstract：:Immunocytochemistry and high-performance liquid chromatography with electrochemical detection (HPLC-ED) were used, more than 76 days after infraorbital nerve (ION) transection, to examine the distribution and density of serotonin-immunoreactive (5-HTIR) axons, as well as serotonin (5-HT) and 5-hydroxyindoleacetic acid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90040-i
更新日期：1990-12-17 00:00:00
abstract：:Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00208-x
更新日期：1998-06-08 00:00:00
abstract：:Cocaine was injected intravenously to non-anesthetized, freely moving adult male rats and caused dose-dependent elevations in plasma adrenocorticotropin (ACTH) levels. The observation that this stimulatory effect was completely abolished by pretreatment with a corticotropin-releasing factor (CRF) antiserum, coupled wi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90953-x
更新日期：1987-10-06 00:00:00
abstract：:The effects of local and global context on concurrent sound segregation were examined using a mistuned harmonic paradigm. Presented with the same sounds over three conditions, participants were asked to either categorise the incoming complex according to pitch or harmonicity (active listening) or watch a muted subtitl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.10.093
更新日期：2008-01-16 00:00:00
abstract：:Recently the nuclear proto-oncogene c-fos has been shown to be rapidly and transiently expressed following seizures in many types of epilepsies. Until now, immunohistochemical as well as in situ hybridization studies have reported that the dentate gyrus of the hippocampus and most of the cortical areas were invariably...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90988-n
更新日期：1990-06-04 00:00:00
abstract：:In chloralose-urethane anaesthetized cats and in one unanesthetized decerebrate cat, the possibility of a baroreceptor pathway exerting an inhibitory effect directly on the sympathetic preganglionic neurone (SPN) was examined. Stimulation of excitatory points in the brain stem and spinal cord evoked responses in T3 wh...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90212-2
更新日期：1981-09-07 00:00:00
abstract：:The phenomenon of unidirectional non-cross tolerance (UNCT) to etorphine was observed in adult male rats tolerant to morphine. Using a morphine pellet (four 75 mg morphine pellets) implantation protocol, a 10-fold increase in the analgesic ED50 value, obtained by tail-flick assay, was observed for morphine sulfate, wi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91502-1
更新日期：1985-02-18 00:00:00
abstract：:To investigate whether tactile spatial attention is modulated by perceptual load, behavioural and electrophysiological measures were recorded during two spatial cuing tasks in which the difficulty of the target/non-target discrimination was varied (High and Low load tasks). Moreover, to study whether attentional modul...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2017.08.007
更新日期：2017-10-15 00:00:00
abstract：:A feature of neurodegenerative disease is the accumulation of insoluble protein aggregates in the brain. In some conditions, including Amyotrophic Lateral Sclerosis and Frontotemporal lobar degeneration, the primary aggregating entities are RNA binding proteins. Through regulated prion-like assembly, RNA binding prote...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.05.052
更新日期：2014-10-10 00:00:00
abstract：:Previous studies employing systemic administration of the dopamine agonist apomorphine have shown that the dose response curves for apomorphine's effects on penile reflexes and seminal emission differ, suggesting that experimentally separable populations of dopamine receptors regulate these two responses. The present ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90328-4
更新日期：1989-10-23 00:00:00
abstract：:Selective D1 (SCH-23390) and D2 (eticlopride and sulpiride) dopamine receptor antagonists were assessed for their ability to reverse the effects of 1.0 mg/kg D-amphetamine on excitatory motor-related neurons in the striatum of freely moving rats. SCH-23390 (0.125, 0.25, 0.5 and 1.0 mg/kg) rapidly and consistently bloc...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91633-4
更新日期：1993-08-13 00:00:00
