Sex-dependent and region-specific changes in TrkB signaling in BDNF heterozygous mice.

abstract：:Finger representation on the first somatosensory cortex was mapped in conscious monkeys by single-unit recording. While representation was somatotopic in area 3, this was not the case in area 2, where the representation of different fingers overlapped. Our results indicate that area 2 is not a pure replica of the rece...

journal_title：Brain research

authors： Iwamura Y,Tanaka M,Hikosaka O

更新日期：1980-09-22 00:00:00

abstract：:Odorant-stimulated formation of cAMP in olfactory receptor neurons may mediate olfactory signal transduction. The response is short and desensitization occurs rapidly, possibly by induction of cyclic nucleotide phosphodiesterase (PDE) activity. Previously, we showed that two low Km PDEs regulate hydrolysis of cAMP in ...

journal_title：Brain research

authors： Borisy FF,Hwang PN,Ronnett GV,Snyder SH

更新日期：1993-05-07 00:00:00

abstract：:NK1 receptor antagonists have been shown to act centrally and to produce a broad-spectrum anti-emetic action. To determine precisely the site of this action, we microinjected GR205171, an NK1 receptor antagonist, into the left medulla oblongata in decerebrate paralyzed dogs. The right medulla was transected 2.5 mm ros...

journal_title：Brain research

authors： Fukuda H,Nakamura E,Koga T,Furukawa N,Shiroshita Y

更新日期：1999-02-13 00:00:00

abstract：:We have investigated the receptor subtype(s) mediating the noradrenergic inhibition of cerebellar Purkinje cell spontaneous firing rate using local application of specific agonists and antagonists, in situ, via pressure microejection. Extracellular action potentials were recorded from Purkinje neurons in anesthetized ...

journal_title：Brain research

authors： Parfitt KD,Freedman R,Bickford-Wimer PC

更新日期：1988-10-18 00:00:00

abstract：:Recent studies have reported microglia that are activated in the central nervous system (CNS) in patients with temporal lobe epilepsy and animal models of epilepsy. However, limited data are available on the dynamic changes of the proportions of various phenotypes of microglia throughout epileptogenesis and whether IL...

journal_title：Brain research

authors： Li T,Zhai X,Jiang J,Song X,Han W,Ma J,Xie L,Cheng L,Chen H,Jiang L

更新日期：2017-02-15 00:00:00

abstract：:Seventy-two hybridoma lines that produce monoclonal antibodies to molecules of a rat synaptosomal plasma membrane fraction (SPM) were generated. The topographical distribution of the antigens in the cerebellum and other areas of the brain was studied by light microscopy immunocytochemistry. Some of the antibodies reco...

journal_title：Brain research

authors： De Blas A,Kuljis RO,Cherwinski HM

更新日期：1984-11-26 00:00:00

abstract：:During the re-entrainment of the rat pineal N-acetyltransferase (NAT) rhythm to an 8-h advance of a light-dark (LD) cycle accomplished by shortening of one dark period, the advanced light period phase-delayed the evening NAT rise and phase-advanced the morning decline. The phase-relationship between the rise and the d...

journal_title：Brain research

authors： Illnerová H

更新日期：1989-08-14 00:00:00

abstract：:Electrophysiological studies on the entopedunculo- and cerebello-thalamic projections were performed by intracellular recordings in the thalamic VA, VL and VM nuclei of cats under sodium pentobarbital anesthesia. Identification of the thalamic neurons were performed electrophysiologically by antidromic activation on s...

journal_title：Brain research

authors： Yamamoto T,Noda T,Miyata M,Nishimura Y

更新日期：1984-06-03 00:00:00

abstract：:Active substance P binding sites were solubilized from rat brain membranes by treatment with 0.125% sodium glycodeoxycholate and 1 M NaCl. About 50% of the binding activity in membrane-bound binding sites was recovered in the solubilized fraction after centrifugation at 105,000 g for 1 h. [3H]Substance P absorbed exte...

journal_title：Brain research

authors： Maruyama M

更新日期：1986-04-02 00:00:00

abstract：:Using gold-labelled somatostatin, somatostatin binding sites were predominantly found in laminae I-III, X and on motorneurones of the rat lumbar spinal cord. A comparison with immunohistochemical staining using antisera against somatostatin receptor sequences revealed that the marked binding in laminae I-III coincided...

journal_title：Brain research

authors： Segond von Banchet G,Schindler M,Hervieu GJ,Beckmann B,Emson PC,Heppelmann B

更新日期：1999-01-16 00:00:00

abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...

journal_title：Brain research

authors： Zhao XC,Zhang LM,Li Q,Tong DY,Fan LC,An P,Wu XY,Chen WM,Zhao P,Wang J

更新日期：2013-11-06 00:00:00

abstract：:Experiments were carried out on hippocampal slices from rats pretreated with a unilateral intraventricular injection of kainic acid. The kainic acid produced a lesion of the CA3 area in the hippocampus ipsilateral to the site of injection. The resulting neuroanatomically modified hippocampal slices allowed the indepen...

journal_title：Brain research

authors： Wheal HV,Lancaster B,Bliss TV

更新日期：1983-08-08 00:00:00

abstract：:The amygdala has long been implicated in conditioned fear. The mesencephalic dopaminergic system provides a rich innervation to the amygdala [J.H. Fallon, P. Ciofi, Distribution of monoamines within the amygdala, in: J.P. Aggleton (Ed.), The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction, ...

journal_title：Brain research

authors： Guarraci FA,Frohardt RJ,Kapp BS

更新日期：1999-05-08 00:00:00

abstract：:In freely-moving female rats the effects of intraventricular infusion of norepinephrine (NE) on multiunit activity (MUA) were examined in the Diagonal Band of Broca (DBB), medial preoptic area (MPOA) and anterior hypothalamic area (AHA), regions containing neurons producing luteinizing hormone-releasing hormone (LHRH)...

journal_title：Brain research

authors： Leung PC,Whitmoyer DI,Arendash GW,Sawyer CH

更新日期：1981-12-07 00:00:00

abstract：:The rat mutant dystonic displays an autosomal recessive neurological disease characterized by slow, twisting movements of the limbs and trunk. Rats displaying clinical signs also show a decreased behavioral response to the dopaminergic blocker, haloperidol. Investigation of the development of the cataleptic response t...

journal_title：Brain research

authors： McKeon TW,Lorden JF,Oltmans GA,Beales M,Walkley SU

更新日期：1984-08-06 00:00:00

abstract：:An increasing number of studies suggest that learning to read changes the way the brain processes spoken language. Yet, there is still a hot debate about the locus of these literacy effects. While most psycholinguists would argue that these effects are late and postlexical, interactive theories of word recognition sug...

journal_title：Brain research

authors： Perre L,Ziegler JC

更新日期：2008-01-10 00:00:00

abstract：:Gonadal steroids have previously been shown to enhance neuritic outgrowth from mouse preoptic area explants in vitro. To examine effects within the explant proper, dendritic fields of Golgi-stained neurons of estradiol-treated and untreated cultures were compared quantitatively. Neurons of gonadal steroid-treated cult...

journal_title：Brain research

authors： Toran-Allerand CD,Hashimoto K,Greenough WT,Saltarelli M

更新日期：1983-03-01 00:00:00

abstract：:Accumulating evidence indicates that extensive microglia activation-mediated local inflammation contributes to neuronal injury in cerebral ischemia. We have previously shown that 4-(2-butyl-6, 7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid (DCPIB), a potent volume-regulated anion channel (VRAC) inhibitor, s...

journal_title：Brain research

authors： Han Q,Liu S,Li Z,Hu F,Zhang Q,Zhou M,Chen J,Lei T,Zhang H

更新日期：2014-01-13 00:00:00

abstract：:We investigated the effect of losartan, a nonpeptide angiotensin II (Ang II)-type 1 (AT1) receptor antagonist, on the responses evoked by Ang II and L-glutamate (L-Glu) in the rostral ventrolateral medulla (RVLM). Adult spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats were anesthetized with halothane ...

journal_title：Brain research

authors： Averill DB,Tsuchihashi T,Khosla MC,Ferrario CM

更新日期：1994-12-05 00:00:00

abstract：:Little is known about the movement of 5-aminolevulinic acid (delta-aminolevulinic acid; ALA) between blood and brain. This is despite the fact that increases in brain ALA may be involved in generating the neuropsychiatric symptoms in porphyrias and that systemic administration of ALA is currently being used to delinea...

journal_title：Brain research

authors： Ennis SR,Novotny A,Xiang J,Shakui P,Masada T,Stummer W,Smith DE,Keep RF

更新日期：2003-01-10 00:00:00

abstract：:Anorexia nervosa is associated with vasopressin, oxytocin and serotonin abnormalities. Because of the relationship between exercise and anorexia nervosa, we explored the weight-loss syndrome produced by wheel running in food-deprived rats. Its effects on regional vasopressin and oxytocin concentrations were determined...

journal_title：Brain research

authors： Aravich PF,Rieg TS,Ahmed I,Lauterio TJ

更新日期：1993-05-28 00:00:00

abstract：:Statistical analysis techniques that permit detection and quantification of EEG-single unit correlations were employed in a study of generalized penicillin epilepsy in the cat. Single unit activity was recorded in cerebral and cerebellar cortices and compared to the locally recorded EEG. It was found that during gener...

journal_title：Brain research

authors： Wray DV,Hablitz JJ

更新日期：1978-10-13 00:00:00

abstract：:The mammalian circadian clock in the suprachiasmatic nuclei (SCN) can be phase-shifted in vitro by the serotonin agonist quipazine. Here we show that quipazine resets the SCN clock in the presence of tetrodotoxin or 10 mM Mg2+, treatments that block Na+ action potentials and Ca2+ channels, respectively. These results ...

journal_title：Brain research

authors： Prosser RA,Heller HC,Miller JD

更新日期：1992-02-28 00:00:00

abstract：:Several regulated mRNAs were detected by applying differential display to the mouse cerebellum during postnatal development. One cDNA fragment, referred to as CPD1 (GenBank U89345), was characterized and cloned. Northern blots showed maximum mRNA expression at postnatal day seven (P7). The mRNA encodes a protein of 26...

journal_title：Brain research

authors： Radrizzani M,Vilá-Ortiz G,Cafferata EG,Di Tella MC,González-Guerrico A,Perandones C,Pivetta OH,Carminatti H,Idoyaga Vargas VP,Santa-Coloma TA

更新日期：2001-07-13 00:00:00

abstract：:Bilateral lesions of the amygdaloid complex in C57BL/6 mice prevented the occurrence of morphine-induced hypermotility (running fit). This effect, that was different from that observed after hippocampal lesions but similar to that observed after caudate lesions, confirms the role of the basal ganglia catecholaminergic...

journal_title：Brain research

authors： Libri V,Ammassari-Teule M,Castellano C

更新日期：1989-02-06 00:00:00

abstract：:During functional spinal neural network activity motoneurons receive massive synaptic excitation and inhibition, and their membrane conductance increases considerably - they are switched to a high-conductance state. High-conductance states can substantially alter response properties of motoneurons. In the present stud...

journal_title：Brain research

authors： Grigonis R,Guzulaitis R,Buisas R,Alaburda A

更新日期：2016-10-01 00:00:00

abstract：:Neuropeptide-Y (NPY) cells in the intergeniculate leaflet (IGL) are known to modulate effects of arousal on the mammalian circadian system. However, the route through which this information reaches the IGL has not been established. Here, we provide evidence that the orexins (hypocretins) are uniquely positioned as a p...

journal_title：Brain research

authors： Nixon JP,Smale L

更新日期：2005-08-16 00:00:00

abstract：:Immunocytochemistry and high-performance liquid chromatography with electrochemical detection (HPLC-ED) were used, more than 76 days after infraorbital nerve (ION) transection, to examine the distribution and density of serotonin-immunoreactive (5-HTIR) axons, as well as serotonin (5-HT) and 5-hydroxyindoleacetic acid...

journal_title：Brain research

authors： Klein BG,Blaker WD

更新日期：1990-12-17 00:00:00

abstract：:L-Tryptophan produces a significant antihypertensive effect in spontaneously hypertensive rats while D-tryptophan does not change blood pressure. Both isomers of tryptophan significantly increase brain serotonin to the same extent at a time when the antihypertensive effect of L-tryptophan is maximal. Thus, the antihyp...

journal_title：Brain research

authors： Wolf WA,Kuhn DM

更新日期：1984-03-19 00:00:00

abstract：:We have used magnetic resonance imaging (MRI) of the living rat brain to longitudinally analyze the ontogenesis of an ibotenic acid lesion targeted at the piriform cortex. The MRI data were systematically compared with data obtained from a battery of histopathological techniques, including Nissl stain, hematoxylin sta...

journal_title：Brain research

authors： Ben-Horin N,Hazvi S,Bendel P,Schul R

更新日期：1996-04-29 00:00:00