Abstract：
:Previous studies employing systemic administration of the dopamine agonist apomorphine have shown that the dose response curves for apomorphine's effects on penile reflexes and seminal emission differ, suggesting that experimentally separable populations of dopamine receptors regulate these two responses. The present experiments examined the locations of central nervous system DA receptors mediating genital responses in the restrained, supine rate by injecting apomorphine into the medial preoptic area and the paraventricular nucleus through chronic, indwelling cannulae. Medial preoptic area injections facilitated penile reflexes, but not seminal emission, while paraventricular injections facilitated seminal emission. These results suggest that systemically administered apomorphine may facilitate penile reflexes by acting on the medial preoptic area and may enhance seminal emission by acting on the paraventricular nucleus.
journal_name
Brain Resjournal_title
Brain researchauthors
Pehek EA,Thompson JT,Hull EMdoi
10.1016/0006-8993(89)90328-4subject
Has Abstractpub_date
1989-10-23 00:00:00pages
325-32issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(89)90328-4journal_volume
500pub_type
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