Biochemical and anatomical consequences of adult infraorbital nerve transection for serotonergic afferents within rat trigeminal subnuclei interpolaris and caudalis.

abstract：:Ascending auditory projections to the nucleus mesencephalicus lateralis pars dorsalis (MLd) were studied in white Leghorn chickens by means of unilateral injections of horseradish peroxidase into the MLd and by injections of tritiated leucine into nucleus angularis or the combined nucleus magnocellularis and nucleus l...

journal_title：Brain research

authors： Conlee JW,Parks TN

更新日期：1986-03-05 00:00:00

abstract：:It has been proposed that disruption of cholinergic input to the hippocampus and cortex contributes to the learning and memory deficits associated with aging. The data reviewed here, however, suggest that the oft-stated generalization that normal aging is characterized by disruption of cholinergic input to the hippoca...

journal_title：Brain research

authors： Decker MW

更新日期：1987-11-01 00:00:00

abstract：:Previous data suggest a relationship between the loss of response to levodopa in Parkinson's disease (PD) patients with the co-occurrence of dementia, but the role of alterations in the dopamine system has not been explored. We measured the extent of striatal DA loss and changes in striatal DA D(2) and D(3) receptors ...

journal_title：Brain research

authors： Joyce JN,Ryoo HL,Beach TB,Caviness JN,Stacy M,Gurevich EV,Reiser M,Adler CH

更新日期：2002-11-15 00:00:00

abstract：:In the neonatal kitten, cuneate neurones activated by tactile stimulation of the forelimb foot pads are divisible into 3 functional classes each of which appears to receive its glabrous skin input selectively from a single class of tactile receptors. Their properties suggest that the functionally specific patterns of ...

journal_title：Brain research

authors： Ferrington DG,Rowe MJ

更新日期：1981-06-01 00:00:00

abstract：:Vascular dysfunction is important in the pathogenesis of peripheral complications of diabetes. However, the effects of diabetes on cerebral blood flow and the role of vascular deficits in the pathogenesis of diabetic encephalopathy are still unknown. The present study examined whether experimental diabetes is associat...

journal_title：Brain research

authors： Manschot SM,Biessels GJ,Cameron NE,Cotter MA,Kamal A,Kappelle LJ,Gispen WH

更新日期：2003-03-21 00:00:00

abstract：:Axonal and glial cell development within rat optic nerve in which gliogenesis was altered by systemic injection of 5-azacytidine (5-AZ) was examined by quantitative electron microscopy. In neonatal (0-2 days) rat optic nerves, all fibers are premyelinated, and they exhibit a fairly uniform diameter (approximately 0.22...

journal_title：Brain research

authors： Black JA,Waxman SG,Ransom BR,Feliciano MD

更新日期：1986-08-13 00:00:00

abstract：:The present experiments showed that there is a cortico-thalamo-cortical projection system in the cat, which originates from the primary visual cortex, relayed by the lateral part of the lateral posterior nucleus of the thalamus, and reaching the medial bank of the lateral suprasylvian visual area. This finding suggest...

journal_title：Brain research

authors： Kato N

更新日期：1990-02-12 00:00:00

abstract：:We have applied a technique involving multi-channel linear filtering to the problem of sorting and identifying singly unit neuronal activity in records containing several simultaneously active units. The technique is effective even when the waveforms of two or more nerve impulses are superimposed. We have applied it s...

journal_title：Brain research

authors： Roberts WM,Hartline DK

更新日期：1975-08-22 00:00:00

abstract：:gamma-Aminobutyric acid (GABA) synthesis in the brain is mediated by two major isoforms of glutamic acid decarboxylase, GAD(65) and GAD(67). The contribution of these isoforms to GABA synthesis flux (V(GAD)) is not known quantitatively. In the present study we compared V(GAD) in cortex of control and vigabatrin-treate...

journal_title：Brain research

authors： Mason GF,Martin DL,Martin SB,Manor D,Sibson NR,Patel A,Rothman DL,Behar KL

更新日期：2001-09-28 00:00:00

abstract：:In continuation of our quantitative studies on 15-day fetal rat brain development, evidence was obtained of ventricular mitoses whose spindles are perpendicular to the surface of the ventricle. In most locations the proportion (ratio) between cells with perpendicular mitoses and predominant cells with mitoses parallel...

journal_title：Brain research

authors： Zamenhof S

更新日期：1987-01-01 00:00:00

abstract：:The herpes virus suis has been used as a tracer for the pathways in the central nervous system of the rat. The viruses have been inoculated in various peripheral structures innervated by the trigeminal nerve, namely in the cornea by instillation or scarification, in the anterior chamber of the eye by injection and als...

journal_title：Brain research

authors： Martin X,Dolivo M

更新日期：1983-08-29 00:00:00

abstract：:In neonates, ventilatory responses to hypoxia are 'biphasic,' with an augmentation followed by a decline. The hypoxia-induced augmentations in ventilation are attenuated and the depressions are accentuated following denervation of the peripheral chemoreceptors. Piglets that were decerebrated at a rostral mesencephalic...

journal_title：Brain research

authors： St-John WM,St Jacques R,Li A,Darnall RA

更新日期：1999-02-20 00:00:00

abstract：:In the present study we found that mesencephalic trigeminal (Mes-V) neurons of the rat are innervated by nitrergic fibers and that nitric oxide (NO) modifies the electrophysiological properties of these cells. Mes-V neurons were surrounded by a network of fibers that contained neuronal nitric oxide synthase (nNOS); th...

journal_title：Brain research

authors： Pose I,Sampogna S,Chase MH,Morales FR

更新日期：2003-01-17 00:00:00

abstract：:Afferent pathways innervating the urinary bladder consist of myelinated Adelta- and unmyelinated C-fibers, the neuronal cell bodies of which correspond to medium and small-sized cell populations of dorsal root ganglion (DRG) neurons, respectively. Since hyperpolarization-activated cyclic nucleotide-gated cation (HCN) ...

journal_title：Brain research

authors： Matsuyoshi H,Masuda N,Chancellor MB,Erickson VL,Hirao Y,de Groat WC,Wanaka A,Yoshimura N

更新日期：2006-11-13 00:00:00

abstract：:The two neurosteroids 3alpha-hydroxy-5alpha-pregnane-20-one (allopregnanolone; AlloP) and pregnenolone sulfate (PregS) affect neuronal GABA(A) receptors differently. While AlloP mainly potentiates the currents through GABA(A) receptors, PregS reduces such currents. The present study aimed at clarifying the interaction...

journal_title：Brain research

authors： Haage D,Bäckström T,Johansson S

更新日期：2005-02-01 00:00:00

abstract：:The effect of arginine vasopressin (AVP) on protein phosphorylation in rat hippocampal synaptic plasma membranes (SPM) was examined. With a crude SPM preparation, AVP (10(-8)-10(-5) M) stimulated phosphorylation of a number of proteins which included a brain-specific protein of 48 kDa called B50 or protein F1, which i...

journal_title：Brain research

authors： Hinko A,Kim Y,Pearlmutter AF

更新日期：1986-10-01 00:00:00

abstract：INTRODUCTION:Ischemic postconditioning (IpostC) has been described in both heart and brain. The first aim of this study was to evaluate the effects of IpostC on brain infarct size and neurological function in the middle cerebral artery occlusion (MCAO) model. The second aim was to determine the involvement of the mitoc...

journal_title：Brain research

authors： Robin E,Simerabet M,Hassoun SM,Adamczyk S,Tavernier B,Vallet B,Bordet R,Lebuffe G

更新日期：2011-02-23 00:00:00

abstract：:Specific binding of [3H]naloxone to rat brain tissue in vitro was inhibited by the excitant organochlorinated insecticides (OCI), by ether (E) and octanol (OCT), and by the convulsant indoklon (IND) and its anesthetic isomer, isoindoklon (ISO). In the presence of 100 mM NaCl the inhibition of naloxone binding by E, OC...

journal_title：Brain research

authors： Labella FS

更新日期：1981-08-24 00:00:00

abstract：:Inflammation probably plays a significant role in perinatal brain injury. To study the contribution of locally produced cytokines, the effect on cell death of addition of IL-8 and MCP-1 or antibodies to these, and the impact of acidosis, human postmitotic NT2-N neurons were exposed to 3 h of hypoxia and glucose depriv...

journal_title：Brain research

authors： Frøyland E,Pedersen ED,Kvissel AK,Almaas R,Pharo A,Skålhegg BS,Mollnes TE,Rootwelt T

更新日期：2006-10-03 00:00:00

abstract：:5-Hydroxytryptamine (5-HT) has been shown to activate the hypothalamo-pituitary-adrenal axis, possibly by a direct action on hypothalamic CRF synthesis and release. In order to study the mechanisms involved in this effect, foetal hypothalamic cells were cultured and corticotropin-releasing factor-41 (CRF) release was ...

journal_title：Brain research

authors： Hu SB,Lightman SL,Tannahill LA

更新日期：1992-03-06 00:00:00

abstract：:Short, high frequency stimulation bursts (4 pulses at 100 Hz) were applied to Schaffer/commissural projections to the CA1 field of rat hippocampal slices at 0.1, 0.2, 1.0 or 2.0-s intervals to assess their efficacy in eliciting long-term potentiation (LTP). Bursts repeated at 2-s intervals induced very little LTP; sho...

journal_title：Brain research

authors： Larson J,Wong D,Lynch G

更新日期：1986-03-19 00:00:00

abstract：:Astaxanthin (AST) is a powerful antioxidant that occurs naturally in a wide variety of living organisms. Much experimental evidence has proved that AST has the function of eliminating oxygen free radicals and can protect organisms from oxidative damage. The present study was carried out to further investigate the neur...

journal_title：Brain research

authors： Lu YP,Liu SY,Sun H,Wu XM,Li JJ,Zhu L

更新日期：2010-11-11 00:00:00

abstract：:Fetal exposure to diazepam (DZ), a positive modulator of GABA(A) receptors and an agonist at mitochondrial benzodiazine receptors, induces long-term neural and behavioral effects. This study evaluated whether the early manipulation influenced the normal development of brain levels of neurosteroids or altered steroid a...

journal_title：Brain research

authors： Kellogg CK,Kenjarski TP,Pleger GL,Frye CA

更新日期：2006-01-05 00:00:00

abstract：:The present study investigated whether the effects of central cholinergic stimulation on thermoregulation during exercise are modulated by arterial baroreceptors. Wistar rats were submitted to sinoaortic denervation (SAD) or sham denervation (SHAM) and then fitted with a chronic guide cannula into the lateral cerebral...

journal_title：Brain research

authors： Pires W,Wanner SP,Lima MR,Oliveira BM,Guimarães JB,de Lima DC,Haibara AS,Rodrigues LO,Coimbra CC,Lima NR

更新日期：2010-12-17 00:00:00

abstract：:The immunocytochemical localization of L-glutamate decarboxylase (GAD), the enzyme which which forms gamma-aminobutyric acid (GABA), has been studied in developing rodent cerebellum. During the first 3-4 postnatal days, GAD is distributed along non-terminal portions of axonal processes in close association with small ...

journal_title：Brain research

authors： McLaughlin BJ,Wood JG,Saito K,Roberts E,Wu JY

更新日期：1975-03-07 00:00:00

abstract：:The effect of microinfusions of cholecystokinin octapeptide (CCK8) and its antagonist L364,718 on duodenal and jejunal motility were evaluated by electromyography in fasted and fed rats. The rats were chronically fitted with electrodes implanted on the duodeno-jejunal wall. Steel cannulas were placed bilaterally in ei...

journal_title：Brain research

authors： Liberge M,Arruebo P,Bueno L

更新日期：1990-01-29 00:00:00

abstract：:Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved in ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and neurological deficits in a standardized model of transient focal cerebra...

journal_title：Brain research

authors： Candelario-Jalil E,González-Falcón A,García-Cabrera M,León OS,Fiebich BL

更新日期：2004-05-08 00:00:00

abstract：:Endothelin-1 (ET-1) has been implicated in hematoma-induced cerebral vasoconstriction and modification of cerebral microvascular reactivity, particularly attenuation of vasodilation to cAMP-dependent dilators and enhanced vasoconstriction to ET-1. We examined effects of the ET-1 antagonist, BQ-123, on hematoma-induced...

journal_title：Brain research

authors： Yakubu MA,Leffler CW

更新日期：1996-09-23 00:00:00

abstract：:Oxidative stress has been implicated as a pathogenic mediator of neuronal perikarya cell death. Axons and oligodendrocytes, components of white matter, could also be vulnerable to oxidative damage. An experimental model of oxidative stress was induced by systemic injection of 3-nitropropionic acid (3-NPA). Animals rec...

journal_title：Brain research

authors： McCracken E,Dewar D,Hunter AJ

更新日期：2001-02-23 00:00:00

abstract：:In zebra finches, androgens stimulate song production and promote growth of the neural regions controlling song. Early exposure to estrogen establishes this sensitivity to androgens and increases the number of androgen-accumulating cells in two song regions, the hyperstriatum ventralis pars caudalis (HVc) and the magn...

journal_title：Brain research

authors： Sohrabji F,Nordeen KW,Nordeen EJ

更新日期：1989-05-29 00:00:00