Abstract：
:Extracellular and intracellular recordings have been made from non-pyramidal neurones in the rat hippocampus in vivo and in vitro. These cells were situated in the stratum pyramidale but were orthodromically activated with a lower threshold than pyramidal neurones in response to stimulation of the Schaffer collateral/commissural afferents. Cells fired earlier than pyramidal neurones in response to suprathreshold stimulation and, in contrast to pyramidal cells, often fired a burst of action potentials. The non-pyramidal neurones also appeared to be orthodromically activated on stimulating the alveus and fired later than antidromically activated pyramidal cells. A very short action potential duration and the ability to fire at high frequencies in response to long depolarizing current pulses also distinguished these neurons from pyramidal cells. It is suggested that these non-pyramidal cells are interneurones which could mediate an early feed-forward activity onto pyramidal cells such as feed-forward inhibition. They may also be recurrently activated and hence could conceivably mediate a recurrent inhibition.
journal_name
Brain Resjournal_title
Brain researchauthors
Ashwood TJ,Lancaster B,Wheal HVdoi
10.1016/0006-8993(84)91235-6subject
Has Abstractpub_date
1984-02-20 00:00:00pages
279-91issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(84)91235-6journal_volume
293pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:In this study the laminar localization of binding sites for the muscarinic radioligand [3H]3-quinuclidinylbenzilate was studied in somatosensory cortex of infant rat. Using light autoradiographic techniques, [3H]QNB was found to be concentrated in layer IV. Atropine-pretreated pups showed evenly dispersed, nonspecific...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(83)90018-4
更新日期：1983-06-01 00:00:00
abstract：:Transcranial magnetic stimulation (TMS) of human lower limb motor cortex paired with common peroneal nerve electrical stimulation produces a lasting modulation of motor cortex excitability following the principles of spike-timing-dependent plasticity. We previously demonstrated that this "paired associative stimulatio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.03.062
更新日期：2007-06-11 00:00:00
abstract：:The pre- and postsynaptic elements of the calyx-type synapse in the chick ciliary ganglion were stained with Lucifer yellow in situ, and the structure of this synapse was examined after enzymatic dissociation of the ganglion. Back-staining of the ciliary nerve resulted in darkly stained neuronal cell bodies. Foreward-...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91309-6
更新日期：1987-09-22 00:00:00
abstract：:The neuropeptide nociceptin/orphanin FQ (N/OFQ) and its receptor are members of the endogenous opioid peptide family. In mammals N/OFQ modulates a variety of biological functions such as nociception, food intake, endocrine, control of neurotransmitter release, among others. In the molluscs Cepea nemoralis and Helix as...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.02.007
更新日期：2013-04-10 00:00:00
abstract：:Following pulse labeling with [3H]arachidonic acid ([3H]AA), its incorporation pattern in brain reflects regional changes in neurotransmitter signal transduction using phospholipase A2, that is, functional activity. In a rat model of Parkinson's disease, unilateral 6-hydroxydopamine lesion in the substantia nigra, [3H...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00751-3
更新日期：1998-10-05 00:00:00
abstract：:Data are presented which show a different pattern of dopamine and noradrenaline utilization in terminal regions of the A9 and A10 dopaminergic systems and in terminal regions of the dorsal noradrenergic bundle after electrical stimulation of the ventral tegmental area and an adjacent area. At the sites of the electrod...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90505-x
更新日期：1983-06-06 00:00:00
abstract：:In a previous study, we demonstrated that cholera toxin-A subunit, as well as the whole toxin, selectively blocks opioid-induced prolongation of the Ca2+ component of the action potential duration (APD) in dorsal root ganglion (DRG) neurons, indicating mediation of this excitatory effect by Gs-linked opioid receptors....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90751-v
更新日期：1990-10-29 00:00:00
abstract：:Axoaxonic synapses are common features of hair-follicle afferent boutons. We have attempted to discover the identity of the neurotransmitter in the associated axon terminals by combining intra-axonal labelling of hair-follicle afferent axons with immunocytochemistry in a correlated light and electron microscopical stu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90394-5
更新日期：1987-04-07 00:00:00
abstract：:Few clinical or experimental studies have carried out systematic investigations of cutaneous and deep sensibility in areas with referred muscle pain. Therefore, no clear signs of increased or decreased psychophysical responses to various somatosensory stimuli are found in referred pain areas. In the present study, a t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01077-3
更新日期：1997-01-02 00:00:00
abstract：:Reflexes evoked by applying non-painful taps to an incisor tooth were recorded from the jaw closing masseter and temporal muscles of 21 human subjects. A series of inhibitory, excitatory, inhibitory and excitatory waves (the 'Q, R, S and T' waves of the post-stimulus electromyographic complex (PSEC)) occurred in full-...
journal_title：Brain research
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-07-08 00:00:00
abstract：:Finger representation on the first somatosensory cortex was mapped in conscious monkeys by single-unit recording. While representation was somatotopic in area 3, this was not the case in area 2, where the representation of different fingers overlapped. Our results indicate that area 2 is not a pure replica of the rece...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)91139-7
更新日期：1980-09-22 00:00:00
abstract：:Immunolabelling for synaptophysin and chromogranin A, two polypeptides associated with small clear and large dense core synaptic vesicles respectively, has been performed on tissue sections of the temporal cortex in Alzheimer's disease in combination with anti-A4 amyloid labelling. The dystrophic neurites in many seni...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90697-t
更新日期：1991-01-18 00:00:00
abstract：:Prenatal cocaine exposure causes alterations in auditory brainstem response in children and experimental animals and has adverse effects on auditory information processing and language skills in children. These effects may result from lesions in the cochlea since this organ is particularly sensitive to chemical insult...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.02.066
更新日期：2006-05-01 00:00:00
abstract：:An in vitro preparation of the medulla oblongata of the rat was used to examine the responses to reducing pH, at constant CO2, of neurons in several identified nuclei. Neurons in an area close to the ventral surface, which is thought to be the location of pH-sensitive central respiratory chemoreceptors, did not respon...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90300-1
更新日期：1983-07-25 00:00:00
abstract：:The existence of spinal neuron collaterals projecting to the intralaminar thalamic nuclei (ILN) and the periaqueductal gray (PAG) was determined in the rat using double-labeling, fluorescent, retrograde axoplasmic transport techniques. Distinctively double-labeled neurons, although not numerous, were found in the enti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90731-6
更新日期：1986-02-12 00:00:00
abstract：:Natural stimulation was used to map the receptive fields of single cells recorded from the rostral medial portion of the dorsal accessory olive (rDAO) and the subjacent principal olive (PO) of the barbiturate anesthetized cat. Previous reports indicated a somatotopic mapping of the entire contralateral body within the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91742-b
更新日期：1993-03-12 00:00:00
abstract：:The purpose of the present study was to examine the effects of N-methyl-D-aspartate (NMDA) receptor blockade on the activity of tuberoinfundibular dopaminergic (TIDA) neurons in male and female rats. TIDA neuronal activity was estimated by measuring either the accumulation of 3,4-dihydroxyphenylalanine (DOPA) 30 min a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91785-q
更新日期：1993-05-14 00:00:00
abstract：:The duration of the sensitive period of the kitten visual cortex to the effects of monocular deprivation was explored by studies of the behavioral and physiological recovery from extended periods of monocular occlusion imposed from birth, and by examination of the physiological effects of a 3 month period of monocular...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)91303-7
更新日期：1980-06-09 00:00:00
abstract：:In the present study we analyzed the effect of ascorbate (0.8 mM)/Fe2+ (2.5 microM)-induced membrane lipid peroxidation on the levels of intracellular free calcium,[Ca2+]i and on the possible mechanisms involved in the perturbation of intracellular calcium homeostasis during oxidative stress. For this purpose, the inf...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01554-x
更新日期：1996-03-25 00:00:00
abstract：:In zebra finches, androgens stimulate song production and promote growth of the neural regions controlling song. Early exposure to estrogen establishes this sensitivity to androgens and increases the number of androgen-accumulating cells in two song regions, the hyperstriatum ventralis pars caudalis (HVc) and the magn...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90715-4
更新日期：1989-05-29 00:00:00
abstract：:We previously reported that glial fibrillary acidic protein (GFAP) levels increased significantly at 3 days after stab wounds, relative to sham-operated controls, reaching a maximum of 200% of control value at 5-7 days. They then fell to near-normal values by 21 days. To determine whether these protein changes correla...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90142-x
更新日期：1990-11-26 00:00:00
abstract：:Acutely (by 48 h), as well as after one month survival, morphine (20 mg/kg) significantly potentiated the extent of noradrenergic degeneration in the forebrain of newborn rats caused by 50 mg/kg of 6-hydroxydopamine (6-OHDA) s.c. This was associated with increased regenerative sprouting in the cerebellum and pons-medu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(85)90167-1
更新日期：1985-10-01 00:00:00
abstract：:Electrical stimulation of the chorda tympani nerve (CT; innervating taste buds on the rostral tongue) is known to initiate recurrent inhibition in cells in the nucleus of the solitary tract (NTS, the first central relay in the gustatory system). Here, we explored the relationship between inhibitory circuits and the br...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.03.069
更新日期：2009-06-12 00:00:00
abstract：:The distribution of immunoreactive (IR) axons and neurons in the rat central nervous system (CNS) has been studied with an antiserum directed against the C-terminal sequence of rat a-calcitonin gene-related peptide (CGRP) and a durable peroxidase reaction product for detailed analysis in relation to normal cytoarchite...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90395-2
更新日期：1988-11-01 00:00:00
abstract：:Oxygen therapy (OT) with hyperbaric oxygen (HBO) or normobaric hyperoxia (NBO) improves the oxygenation of penumbral tissue in experimental ischemic stroke. However, whether this results in the improvement of energy metabolism is unclear. We investigated the effect of both OTs on tissue acidosis and on ATP production....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.07.064
更新日期：2011-09-30 00:00:00
abstract：:We elucidated how Alzheimer-type pathologies of amyloid beta-protein (Abeta) and tau spatiotemporally emerge in brains of nontransgenic nonhuman primate, cynomolgus monkey, in the present study. To examine the accumulation of deposited Abeta, phosphorylated tau accumulation, intracellular tau accumulation, and neurofi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.12.005
更新日期：2010-02-22 00:00:00
abstract：:It is well known that the nerve growth factor (NGF) may serve as a link between inflammation and hyperalgesia. Recent experiments showed that systemic injection of NGF dramatically stimulated the expression of brain-derived neurotrophic factor (BDNF) mRNA in the dorsal root ganglion (DRG). In the present study, we eva...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/S0006-8993(97)00048-6
更新日期：1997-02-28 00:00:00
abstract：:Extracellular recordings were made from a type of relay neurons of the superior laryngeal nerve (SLN) afferents in the vicinity of the retrofacial nucleus (RFN) in either pentobarbitone-anesthetized or unanesthetized and decerebrate cats, which were paralyzed and artificially ventilated. A total of 26 neurons that cou...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91156-m
更新日期：1993-12-31 00:00:00
abstract：:A rabbit polyclonal antibody (91-01) was raised against recombinant human glia maturation factor beta (r-hGMF-beta). The antibody did not cross-react with a number of other growth factors on ELISA test. When compared with the monoclonal antibody G2-09 previously obtained, 91-01 immunoblotted the same protein band in r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90971-b
更新日期：1992-09-18 00:00:00
abstract：:Nitric oxide (NO), a potent vasodilator and nontraditional neurotransmitter, is an important mediator of the changes in cerebral blood flow (CBF) associated with increased neuronal activity (neurovascular coupling). In the present work, we investigated the role of NO and of its newly recognized precursor, nitrite, in ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.06.045
更新日期：2011-08-17 00:00:00
