Expression of mRNA for brain-derived neurotrophic factor in the dorsal root ganglion following peripheral inflammation.

abstract：:Field potentials and radial current source-densities (CSDs) evoked by optic tract stimulation were observed in goldfish tectum in vitro. The effects of different concentrations of calcium and magnesium were studied to improve understanding of component events in retinotectal transmission and interpretations of effects...

journal_title：Brain research

authors： Langdon RB,Manis PB,Freeman JA

更新日期：1988-02-16 00:00:00

abstract：:The aim of this study was (i) to compare the immunocytochemical distribution of the calcium-binding protein calbindin-D28k (CB) in the hippocampus of rats with the pattern of neurodegeneration following adrenalectomy (ADX) using silver impregnation, and (ii) to investigate the CB-immunoreactivity in the hippocampus fo...

journal_title：Brain research

authors： Krugers HJ,Medema RM,Postema F,Korf J

更新日期：1995-10-23 00:00:00

abstract：:Glial cells play a crucial role in the pathomechanism of perinatal hypoxic-ischemic brain injury (HI) and are involved in the maintenance of a chronic state of inflammation that causes delayed neuronal damage. Activation of astrocytes is one factor prolonging brain damage and contributing to the formation of a glial s...

journal_title：Brain research

authors： Wasielewski B,Jensen A,Roth-Härer A,Dermietzel R,Meier C

更新日期：2012-12-03 00:00:00

abstract：:Cingulate cortex (CC) unit responses to hippocampal volleys and afterdischarges were studied in 4 awake unsedated squirrel monkeys using extracellular microelectrodes. Stimuli were delivered via bipolar electrodes chronically implanted bilaterally in anterior and posterior hippocampus. A total of 412 units in 21 track...

journal_title：Brain research

authors： Dagi TF,Poletti CE

更新日期：1983-01-24 00:00:00

abstract：:The effect of lung inflation on the excitability of inspiratory neurons of the dorsal respiratory group was studied in decerebrate, paralyzed, artificially ventilated cats. Variations in the antidromic latency (AL) were used as a measure of the changes in excitability. The antidromic responses of single cells were rec...

journal_title：Brain research

authors： Davies RO,Metzler J,Silage DA,Pack AI

更新日期：1986-02-26 00:00:00

abstract：:Administration of methyl palmoxirate (MP), an inhibitor of fatty acid oxidation, stimulates eating behavior in rats. Fos immunohistochemistry was used to determine neural pathways that may play a role in the eating response to MP. The number of cells showing Fos-like immunoreactivity (Fos-li) was quantified by compute...

journal_title：Brain research

authors： Horn CC,Friedman MI

更新日期：1998-01-19 00:00:00

abstract：:The neocortex has proven resistant to LTP induction using standard in vitro and acute, in vivo preparations. Because the neocortex is widely thought to be involved in long-term information storage, this resistance raises questions about the validity of LTP as a memory model. Recently, we have shown that the neocortex ...

journal_title：Brain research

authors： Boyd TE,Trepel C,Racine RJ

更新日期：2000-10-20 00:00:00

abstract：:Nestin is an embryonic intermediate filament that transiently expressed in the neural stem/progenitor cells in the developing central nervous system (CNS). Growing evidence has shown that abundant expression of nestin also occurs in both pathological glial-derived tumor cells and reactive astrocytes in various CNS inj...

journal_title：Brain research

authors： Wei LC,Shi M,Cao R,Chen LW,Chan YS

更新日期：2008-02-27 00:00:00

abstract：:Nitric oxide (NO) production in the sensory neurons of the rad nodose ganglion was studied by examining the distribuiotn of NO synthase (NOS) by use of NADPH diaphorase (NADPHD) histochemistry and immunohistochemistry ofr the presence of isoformes of NOS: neuronal (nNOS), endothelial (eNOS) and the inducible isoform (...

journal_title：Brain research

authors： Yamamoto Y,Henrich M,Snipes RL,Kummer W

更新日期：2003-01-24 00:00:00

abstract：:Three priming injections with the D1/D2 dopamine agonist apomorphine permits a challenge with the D2 agonist quinpirole to elicit robust contralateral rotation and ipsilateral striatal Fos expression in 6-hydroxydopamine lesioned rats. Pretreatment with NMDA glutamate antagonists MK-801 or CPP dose-dependently attenua...

journal_title：Brain research

authors： Pollack AE,Haisley EC

更新日期：2001-04-06 00:00:00

abstract：:Tumor suppressor p53 has recently been reported to have numerous functions independent of tumorigenesis, including neuronal survival during ischemia. The mammalian target of rapamycin (mTOR) signaling pathway plays a central role in the regulation of metabolism, cell growth, development, and cell survival. Our recent ...

journal_title：Brain research

authors： Li X,Gu S,Ling Y,Shen C,Cao X,Xie R

更新日期：2015-04-24 00:00:00

abstract：:Long-term potentiation (LTP) has received considerable attention as a neurophysiological model for studying the biology of memory. The present experiments examined the susceptibility of LTP in the dentate gyrus to modification by peripheral injections of amphetamine and epinephrine. Both drugs enhanced the development...

journal_title：Brain research

authors： Gold PE,Delanoy RL,Merrin J

更新日期：1984-07-02 00:00:00

abstract：:Direct microinjection of cholinergic compounds into pontine reticular formation furnishes an excellent phenomenological model of the rapid eye movement phase of sleep (REM), but the mechanisms underlying this effect and whether they mimic the cellular events of natural REM remain unknown. Data presented here from intr...

journal_title：Brain research

authors： Greene RW,Gerber U,McCarley RW

更新日期：1989-01-02 00:00:00

abstract：:Several studies have demonstrated in the past that endogenous opioid peptides and opioid receptors may be involved as mediators of brain tissue growth and function in the neonate. Applying histological and autoradiographic methods, we have examined the effect of the mu-receptor-specific antagonist, naltrexone, on the ...

journal_title：Brain research

authors： Schmahl W,Funk R,Miaskowski U,Plendl J

更新日期：1989-05-08 00:00:00

abstract：:Recent neurocognitive studies of visual word recognition provide information about neuronal networks correlated with processes involved in lexical access and their time course (e.g., [Holcomb, Ph.J., Grainger J. and O'Rourke, T. (2002). An Electrophysiological Study of the Effects of Orthographic Neighborhood Size on ...

journal_title：Brain research

authors： Braun M,Jacobs AM,Hahne A,Ricker B,Hofmann M,Hutzler F

更新日期：2006-02-16 00:00:00

abstract：:The N-methyl-d-aspartate (NMDA) receptor, a glutamate receptor subtype, is a ligand-gated ion channel. Overstimulation of NMDA receptors may increase intracellular Ca2+ concentrations to lethal levels in neurodegenerative disorders affecting the basal ganglia. Such excitotoxicity may also contribute to the loss of med...

journal_title：Brain research

authors： Hopkins KJ,Oster-Granite ML

更新日期：1998-06-29 00:00:00

abstract：:One hour after long-term potentiation (LTP) in the intact hippocampus, a selective increase in protein F1 in vitro phosphorylation was observed in homogenate prepared from dorsal hippocampus. Protein F1 phosphorylation was directly related to the magnitude and persistence of potentiation. No other phosphoprotein studi...

journal_title：Brain research

authors： Lovinger DM,Colley PA,Akers RF,Nelson RB,Routtenberg A

更新日期：1986-12-10 00:00:00

abstract：:The hallucinogen d-lysergic acid diethylamide (d-LSD) evokes dramatic somatic and psychological effects. In order to analyze the neural activation induced by this unique psychoactive drug, we tested the hypothesis that expression of the immediate-early gene product c-Fos is induced in specific regions of the rat foreb...

journal_title：Brain research

authors： Frankel PS,Cunningham KA

更新日期：2002-12-27 00:00:00

abstract：:Both enkephalin and 5-hydroxytryptamine (5-HT) have been implicated in neural mechanisms underlying the central control of respiration. In view of the role of the nuclei tractus solitarii (NTS) in respiratory regulation, we carried out a study in artificially ventilated, chloralose-anaesthetized cats of the effects of...

journal_title：Brain research

authors： Sessle BJ,Henry JL

更新日期：1985-02-18 00:00:00

abstract：:The distribution of substance P receptors was examined by autoradiography at all levels of the human postmortem spinal cord using the ligand [125I]Bolton-Hunter substance P. Adjacent sections were used to localize substance P-like immunoreactivity by a radioimmunohistochemical technique. In the control spinal cord sub...

journal_title：Brain research

authors： Dietl MM,Sanchez M,Probst A,Palacios JM

更新日期：1989-03-27 00:00:00

abstract：:This study attempted to ascertain whether heatstroke-induced ischemia is associated with augmented striatal glutamate release and can be attenuated by NMDA receptor antagonists. Mean arterial pressure (MAP), striatal cerebral blood flow (CBF), striatal glutamate release and striatal neuronal damage score were assessed...

journal_title：Brain research

authors： Yang YL,Pan WH,Chiu TH,Lin MT

更新日期：1998-06-08 00:00:00

abstract：:Little is known about putative transmitters in the nucleus ambiguus (NA) mediating parasympathetic control of the heart, although Met-enkephalin (m-ENK), Leu-enkephalin (l-ENK), substance P (SP) and acetylcholine (Ach) have been detected in the cell bodies and fibers of this nucleus. The effects of these substances on...

journal_title：Brain research

authors： Agarwal SK,Calaresu FR

更新日期：1991-11-01 00:00:00

abstract：:The synaptic connections between frog retinal ganglion cells and tectal neurons were examined by whole-cell recordings in vivo combined with nystatin perforated patch-clamp technique and pulse-triggered averaging analysis. In five tectal neurons, monosynaptic EPSPs from seven R3 retinal ganglion cells were observed. O...

journal_title：Brain research

authors： Nakagawa H,Kikkawa S,Matsumoto N

更新日期：1994-12-05 00:00:00

abstract：:Acute forebrain ischemia reduced protein kinase C (PKC) activity in the adult rat cortex, striatum and hippocampus by 60-70% after 20 min ischemia episodes, followed by 48 h of recirculation. Ischemia of 1 min, followed by recirculation, produced a less pronounced but significant decrease in PKC activity. The ischemia...

journal_title：Brain research

authors： Louis JC,Magal E,Brixi A,Steinberg R,Yavin E,Vincendon G

更新日期：1991-02-08 00:00:00

abstract：:The present study examined the antioxidant effect of phytic acid on iron (II)-enhanced hydroxyl radical (*OH) generation induced by 1-methyl-4-phenylpyridinium ion (MPP(+)) in the extracellular fluid of rat striatum. Rats were anesthetized, and sodium salicylate in Ringer's solution (0.5 nmol/microl/min) was infused t...

journal_title：Brain research

authors： Obata T

更新日期：2003-07-18 00:00:00

abstract：:We examined the electrophysiological properties of cholinergic and non-cholinergic neurons in the medial septum-diagonal band complex (MSDB) of the rat in the in vitro slice preparation. Cells were identified electrophysiologically, filled with Lucifer yellow, fixed and processed for immunohistochemistry with fluoresc...

journal_title：Brain research

authors： Markram H,Segal M

更新日期：1990-04-09 00:00:00

abstract：:Fluorescence resonance energy transfer (FRET) is a widely utilized optical technique for measuring small distances of 1-10 nm in live cells. In recent years, its application has been greatly popularized by the discovery of green fluorescent protein (GFP) and many improved variants which make good donor-acceptor fluoro...

journal_title：Brain research

authors： Takanishi CL,Bykova EA,Cheng W,Zheng J

更新日期：2006-05-26 00:00:00

abstract：:Amphetamine withdrawal is associated with heightened anxiety-like behavior, which is directly driven by blunted stress-induced glucocorticoid receptor-dependent serotonin release in the ventral hippocampus. This suggests that glucocorticoid availability in the ventral hippocampus during stress may be reduced during am...

journal_title：Brain research

authors： Bray B,Scholl JL,Tu W,Watt MJ,Renner KJ,Forster GL

更新日期：2016-08-01 00:00:00

abstract：:Ventilation is peripherally controlled by afferent activity arising from the peripheral chemoreceptors. In the rat, chemosensory activity is conveyed to the central nervous system through axons of neurons located in the nodose-petrosal-jugular-complex. These neurons have distinct electrophysiological properties, inclu...

journal_title：Brain research

authors： Alcayaga J,Oyarce MP,Del Rio R

更新日期：2016-10-15 00:00:00

abstract：:Mutations in two genes, alpha-synuclein and parkin, have been identified as some rare causes for familial Parkinson's disease (PD). alpha-Synuclein and parkin protein have subsequently been identified in Lewy bodies (LB). To gain further insight into the pathogenesis of PD we investigated the role of neurofilament lig...

journal_title：Brain research

authors： Rahner N,Holzmann C,Krüger R,Schöls L,Berger K,Riess O

更新日期：2002-09-27 00:00:00