Abstract：
:Antagonism of the alpha receptor sub-type at gamma-aminobutyric acid (GABA) recognition sites in developing pigs was evaluated using the GABAA receptor antagonist bicuculline. The effect of bicuculline infusions was to produce an increase of phrenic and hypoglossal discharge amplitudes. This bicuculline-induced effect on discharge amplitude was manifested in autopower spectra as an increase in the power of peaks located in the medium-frequency (10-50 Hz) band. More importantly, coherence estimates were increased by bicuculline administration demonstrating GABA-mediated influences on a central pattern generator with output in the 10-50 Hz band.
journal_name
Brain Resjournal_title
Brain researchauthors
Steele AM,Siddiqi ZA,Sica ALdoi
10.1016/0006-8993(94)90222-4subject
Has Abstractpub_date
1994-07-04 00:00:00pages
166-9issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(94)90222-4journal_volume
650pub_type
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