An intracellular study of Renshaw cells.

abstract：:The relationship between the dorsal raphe neurons projecting to the caudate-putamen and those projecting to the substantia nigra was investigated using a fluorescent retrograde double labeling technique in the rat. The majority of the dorsal raphe neurons projecting to the substantia nigra were found to project also t...

journal_title：Brain research

authors： van der Kooy D,Hattori T

更新日期：1980-03-17 00:00:00

abstract：:Female B6C3F1 mice were rendered tolerant-dependent on morphine by a combination of injections and pellet implantation. Mice were injected with morphine sulfate (20 mg/kg, s.c.) twice a day on day 1. On day 2, they were implanted s.c. with a 75 mg morphine pellet for 3 days. On day 5, the pellets were either left inta...

journal_title：Brain research

authors： Bhargava HN,Thomas PT,Thorat S,House RV

更新日期：1994-04-11 00:00:00

abstract：:By using immunocytochemistry we tested whether neurotransmitters, and enzymes specific to neurotransmitters synthesis are rhythmically expressed in the suprachiasmatic nuclei of the hypothalamus of Ruin lizards Podarcis sicula either kept in light-dark cycles or constant darkness. Within the suprachiasmatic nuclei, pr...

journal_title：Brain research

authors： Magnone MC,Bertolucci C,Piazza F,Foà A

更新日期：2003-05-23 00:00:00

abstract：:Post-traumatic invasion of macrophages into the cochlear nerve of the rat and measurement of how their invasion was modified by the administration of methylprednisolone were investigated for the first time by using a reproducible and quantifiable experimental model of cochlear nerve injury. Two weeks after precise coc...

journal_title：Brain research

authors： Sekiya T,Tanaka M,Shimamura N,Suzuki S

更新日期：2001-06-29 00:00:00

abstract：:Mice pretreated with the benzodiazepine antagonist, CGS 8216 (2.5, 10, or 40 mg/kg, i.p.) learned a T-maze discrimination to a fixed performance criterion more rapidly than vehicle-treated mice. In retention tests conducted one week later, the drug-treated groups had better first-trial recall and greater difficulty re...

journal_title：Brain research

authors： Kumar BA,Forster MJ,Lal H

更新日期：1988-09-13 00:00:00

abstract：:A motor disorder similar to idiopathic Parkinson's Disease develops in rhesus monkeys after several daily repeated doses of N-methyl-4-phenyl, 1,2,3,6-tetrahydropyridine (MPTP). The concentrations of peptides derived from proenkephalin A, proenkephalin B, substance P and somatostatin were measured by specific radioimm...

journal_title：Brain research

authors： Zamir N,Skofitsch G,Bannon MJ,Helke CJ,Kopin IJ,Jacobowitz DM

更新日期：1984-11-26 00:00:00

abstract：:There is a sizeable literature concerning basal ganglia (BG) functioning that is based on data from experiments employing a method of analysis that is traditionally used with other motor areas. A brief review of this literature is presented and the following conclusion is reached: as compared to the success of traditi...

journal_title：Brain research

authors： Lidsky TI,Manetto C,Schneider JS

更新日期：1985-06-01 00:00:00

abstract：:Transthyretin (TTR) is mainly expressed in the liver and choroid plexus of the brain. The majority of familial amyloidotic polyneuropathy cases are caused by a mutant TTR gene. The origin of the TTR deposited in the peripheral nervous system is unknown. We studied the expression of TTR in the peripheral nerves of norm...

journal_title：Brain research

authors： Murakami T,Ohsawa Y,Zhenghua L,Yamamura K,Sunada Y

更新日期：2010-08-12 00:00:00

abstract：:In a previous study the collateralization of the rubrospinal tract in the spinal cord of rat, cat and monkey was studied by means of the fluorescent retrograde double labeling technique. In the present study the existence of rubrospinal collaterals to the cerebellar interpositus nucleus (NI) has been studied using the...

journal_title：Brain research

authors： Huisman AM,Kuypers HG,Condé F,Keizer K

更新日期：1983-04-04 00:00:00

abstract：:Although transsynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characterized, several methodological issues related to central application of this tracer have not been addressed. In the present study, we addressed the following three issues by using microinjection of a cockta...

journal_title：Brain research

authors： Chen S,Yang M,Miselis RR,Aston-Jones G

更新日期：1999-08-14 00:00:00

abstract：:Iontophoretic application of carbachol caused excitation of CA1 neurones and decreased the amplitude of antidromic CA1 population spikes recorded extracellularly. Adenosine, adenosine triphosphate (ATP) and the purine analogues N-ethylcarboxamide adenosine (NECA) and R- and S-phenylisopropyladenosine (PIA) reduced the...

journal_title：Brain research

authors： Brooks PA,Stone TW

更新日期：1988-08-16 00:00:00

abstract：:Exposure of newborn rats to antiepileptics such as barbiturates has long-lasting detrimental effects on the hippocampus and hippocampus-dependent behavior. However, the long-term consequences of neonatal administration with barbiturates on the hippocampal synaptic plasticity remain unresolved. In this study, we invest...

journal_title：Brain research

authors： Tachibana K,Hashimoto T,Kato R,Tsuruga K,Ito R,Morimoto Y

更新日期：2011-05-04 00:00:00

abstract：:Heme oxygenase-carbon monoxide-cGMP (HO-CO-cGMP) pathway has been reported to be involved in peripheral and spinal modulation of inflammatory pain. However, the involvement of this pathway in the modulation of acute painful stimulus in the absence of inflammation remains unknown. Thus, we evaluated the involvement of ...

journal_title：Brain research

authors： Carvalho PG,Branco LG,Panissi CR

更新日期：2011-04-18 00:00:00

abstract：:Systemic administration of 3-nitropropionic acid (3-NP) results in striatal atrophy by irreversibly inhibiting the citric acid cycle, and thereby resulting in cellular ATP depletion. The neuropathological outcome following 3-NP injections is thought to resemble that seen in Huntington's disease (HD) [1]. The current s...

journal_title：Brain research

authors： Koutouzis TK,Borlongan CV,Scorcia T,Creese I,Cahill DW,Freeman TB,Sanberg PR

更新日期：1994-05-23 00:00:00

abstract：:The rostral projection of A delta and C primary afferents in Lissauer's tract (LT) was studied by assessing how far, rostrally, axons entering at a given level could be activated by electrical stimulation. Sural A delta primary afferents in LT exhibited a rostral projection at least as far as the L3/L4 border, 4 segme...

journal_title：Brain research

authors： Traub RJ,Sedivec MJ,Mendell LM

更新日期：1986-12-03 00:00:00

abstract：:The possible involvement of protein kinase A (PKA) in the muscarinic inhibition of the slow afterhyperpolarizing current (IAHP) was investigated in rat hippocampal pyramidal cells. IAHP was recorded using the whole cell method in hippocampal slices, and Rp-cAMPS, a PKA antagonist, was applied intracellularly. The inhi...

journal_title：Brain research

authors： Blitzer RD,Wong T,Nouranifar R,Landau EM

更新日期：1994-05-23 00:00:00

abstract：:Responses to rotation in many vertical and horizontal planes were studied in electrically identified secondary vestibular neurons of alert cats. This report concerns secondary neurons that gave responses which could not be explained as due to a summation of semicircular canal inputs. These cells responded to sinusoida...

journal_title：Brain research

authors： Baker J,Goldberg J,Hermann G,Peterson B

更新日期：1984-02-27 00:00:00

abstract：:Available evidence suggests that a portion of the septohippocampal pathway may form inhibitory synapses on inhibitory interneurons in the dentate gyrus. In contrast, a portion of the commissural input from the contralateral hilus may form excitatory synapses on inhibitory interneurons. To ascertain whether these pathw...

journal_title：Brain research

authors： Bilkey DK,Goddard GV

更新日期：1987-03-10 00:00:00

abstract：:The effects of neonatal dopamine depletion on activity levels and locomotor patterns were tested in rats at 4 months of age. Measurements were taken using an activity pattern monitor. The lesioned group was significantly hypoactive in comparison to the control animals during the initial exposures to the monitor. Exami...

journal_title：Brain research

authors： Moy SS,Breese GR,Eckerman DA

更新日期：1994-05-09 00:00:00

abstract：:To determine the involvement of vasoactive intestinal polypeptide (VIP) in the development of kindling in rats, VIP or antibody to VIP (anti-VIP) was injected into the third ventricle after the daily stimulation of the basolateral amygdala. The number of stimulations required to reach full amygdaloid kindling was sign...

journal_title：Brain research

authors： Funabashi T,Hiruma H,Arita J,Kimura F

更新日期：1991-02-08 00:00:00

abstract：:Recent evidence has suggested that cholecystokinin (CCK) may act as a physiological opiate antagonist. Both the overlap of CCK and opiate systems within the central nervous system and the fact that exogenous CCK can antagonize opiate analgesia suggest that endogenous CCK systems interact with opiate-mediated pain inhi...

journal_title：Brain research

authors： Watkins LR,Kinscheck IB,Mayer DJ

更新日期：1985-02-18 00:00:00

abstract：:The acute intravenous administration of high doses of methylprednisolone sodium succinate (15-90 mg/kg) to cats enhanced (Na+ + K+)-ATPase activity as much as 2-fold in synaptosomes prepared from lumbar spinal cord removed following drug administration. The effect was apparent within 5 min and was statistically signif...

journal_title：Brain research

authors： Braughler JM,Hall ED

更新日期：1981-08-31 00:00:00

abstract：:Zinc was measured in whole hippocampus and in hippocampal sub-regions by stable-isotope dilution mass spectrometry. In both man and the rat, the most zinc (102-145 ppm, dry weight) was found in the hilar region, the least (27-35) in the fimbria. The amount of zinc directly associated with mossy-fiber axons was estimat...

journal_title：Brain research

authors： Frederickson CJ,Klitenick MA,Manton WI,Kirkpatrick JB

更新日期：1983-08-29 00:00:00

abstract：:Tetanic stimulation at 50 Hz elicited long-term potentiation (LTP) in the hippocampal CA1 region of 28-day-old control animals. In contrast, no significant potentiation was seen following the same tetanus in animals chronically exposed to 1000 ppm of lead acetate during development. Gender differences were observed in...

journal_title：Brain research

authors： Zaiser AE,Miletic V

更新日期：2000-09-08 00:00:00

abstract：:The effect of microinfusions of cholecystokinin octapeptide (CCK8) and its antagonist L364,718 on duodenal and jejunal motility were evaluated by electromyography in fasted and fed rats. The rats were chronically fitted with electrodes implanted on the duodeno-jejunal wall. Steel cannulas were placed bilaterally in ei...

journal_title：Brain research

authors： Liberge M,Arruebo P,Bueno L

更新日期：1990-01-29 00:00:00

abstract：:The possibility that the opioid delta-receptor mediates antinociception in tests where heat is the noxious stimulus was investigated using highly selective mu- and delta-agonist and -antagonists. Antinociceptive dose-response curves were constructed for mu ([D-Ala2,NMePhe4,Gly-ol]enkephalin, DAGO; morphine) and delta ...

journal_title：Brain research

authors： Heyman JS,Mulvaney SA,Mosberg HI,Porreca F

更新日期：1987-09-08 00:00:00

abstract：:Indirect immunofluorescence cytochemistry of ovine corticotropin releasing factor (oCRF) was performed by use of an antiserum raised against a conjugate of oCRF and bovine thyroglobulin. The staining intensity was quantitated by use of an automated microfluorimeter. In cryostat sections of formaldehyde fixed oCRF cont...

journal_title：Brain research

authors： Schipper J,Werkman TR,Tilders FJ

更新日期：1984-02-13 00:00:00

abstract：:Lithium is detected in the mouse brain with the aid of a (n,alpha) nuclear reaction. The resolving power is of a few micron. The detection efficiency is estimated in a first series of experiments with brain sections of progressively increasing thickness. This allows us to make the microlocation of lithium in the brain...

journal_title：Brain research

authors： Thellier M,Heurteaux C,Wissocq JC

更新日期：1980-10-13 00:00:00

abstract：:Poor sleep and insomnia have been recognized to be strongly correlated with the development of depression. The exploration of the basic mechanism of sleep disturbance could provide the basis for improved understanding and treatment of insomnia and prevention of depression. In this study, 31 subjects with insomnia symp...

journal_title：Brain research

authors： Liu CH,Liu CZ,Zhang J,Yuan Z,Tang LR,Tie CL,Fan J,Liu QQ

更新日期：2016-10-01 00:00:00

abstract：:The effect of immunoneutralization of hypothalamic neuropeptide Y (NPY) on food intake was examined to clarify the involvement of NPY in the control mechanism of feeding behavior. Injection of anti-NPY gamma-globulin into the bilateral hypothalamic paraventricular nuclei of 24-h food-deprived rats significantly inhibi...

journal_title：Brain research

authors： Shibasaki T,Oda T,Imaki T,Ling N,Demura H

更新日期：1993-01-22 00:00:00