当前位置： SCI文献检索 > BRAIN RESEARCH期刊下所有文献 > Daily and circadian rhythms of neurotransmitters and related compounds in the hypothalamic suprachiasmatic nuclei of a diurnal vertebrate.

Daily and circadian rhythms of neurotransmitters and related compounds in the hypothalamic suprachiasmatic nuclei of a diurnal vertebrate.

Abstract：

:By using immunocytochemistry we tested whether neurotransmitters, and enzymes specific to neurotransmitters synthesis are rhythmically expressed in the suprachiasmatic nuclei of the hypothalamus of Ruin lizards Podarcis sicula either kept in light-dark cycles or constant darkness. Within the suprachiasmatic nuclei, prominent 24 h rhythms under 12:12 light-dark cycles were found for vasoactive intestinal polypeptide (VIP) and for tyrosine hydroxylase (TH). Peaks of both VIP and TH fell in the light phase of the cycle. Rhythmic expression of TH persisted under constant temperature and darkness, demonstrating the existence of circadian rhythms of TH in the suprachiasmatic nuclei. No rhythmic expression of neurotransmitters and related compounds was found in the periventricular nuclei, the supraoptic nuclei, and the rest of the hypothalamus. Our data are the first demonstration of rhythmic expression of neurotransmitters and related compounds in the suprachiasmatic nuclei of a non-mammalian vertebrate. The demonstration of a diurnal peak of VIP in a diurnal reptile-vs. nocturnal peak of VIP typical of nocturnal mammals-provides new information for comparative studies on the circadian physiology of the suprachiasmatic nuclei across vertebrate classes and their adaptation strategies to different temporal niches.

journal_name

Brain Res

journal_title

Brain research

authors

Magnone MC,Bertolucci C,Piazza F,Foà A

doi

10.1016/s0006-8993(03)02567-8

subject

Has Abstract

pub_date

2003-05-23 00:00:00

pages

115-21

issue

1

eissn

0006-8993

issn

1872-6240

pii

S0006899303025678

journal_volume

973

pub_type

杂志文章

相关文献

BRAIN RESEARCH文献大全
  • Chronic estradiol treatment alters central cholinergic function in the female rat: effect on choline acetyltransferase activity, acetylcholine content, and nicotinic autoreceptor function.

    abstract：:The purpose of the present study was to determine the effects of chronic (2-month) estradiol (E2) treatment on cholinergic function in the frontal cortex, hippocampus and hypothalamus of the female rat. Chronic E2 treatment selectively increased choline acetyltransferase (ChAT) activity in the frontal cortex and decre...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(90)90871-8

    authors： Lapchak PA,Araujo DM,Quirion R,Beaudet A

    更新日期：1990-08-20 00:00:00

  • Stress rapidly increases alpha 1d adrenergic receptor mRNA in the rat dentate gyrus.

    abstract：:The hippocampal formation is a highly plastic brain region that is sensitive to stress. It receives extensive noradrenergic projections, and noradrenaline is released in the hippocampus in response to stressor exposure. The hippocampus expresses particularly high levels of the alpha(1D) adrenergic receptor (ADR) and w...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2010.01.084

    authors： Campeau S,Nyhuis TJ,Kryskow EM,Masini CV,Babb JA,Sasse SK,Greenwood BN,Fleshner M,Day HE

    更新日期：2010-04-06 00:00:00

  • Sleep restriction by forced activity reduces hippocampal cell proliferation.

    abstract：:Mounting evidence suggests that sleep loss negatively affects learning and memory processes through disruption of hippocampal function. In the present study, we examined whether sleep loss alters the generation, differentiation, and survival of new cells in the dentate gyrus. Rats were sleep restricted by keeping them...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2005.10.020

    authors： Roman V,Van der Borght K,Leemburg SA,Van der Zee EA,Meerlo P

    更新日期：2005-12-14 00:00:00

  • Effects of nicotinic agonists on the NMDA receptor.

    abstract：:The cholinergic nicotinic agonists (-)nicotine and lobeline were observed to partially inhibit whole-cell N-methyl-D-aspartate (NMDA)-induced responses in rat cortical neurons in culture. In addition we found that (-)nicotine, (+)nicotine, and lobeline, but not the nicotine metabolite (-)cotinine nor acetylcholine, we...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(91)90958-x

    authors： Aizenman E,Tang LH,Reynolds IJ

    更新日期：1991-06-14 00:00:00

  • Blockade of the spinal excitatory effect of cAMP on the startle reflex by intrathecal administration of the isoquinoline sulfonamide H-8: comparison to the protein kinase C inhibitor H-7.

    abstract：:Drugs thought to inhibit the actions of protein kinase C (PKC) and cAMP dependent protein kinase (A-kinase) were infused intrathecally into the subarachnoid space of the lumbar region of the spinal cord, and the effects on acoustic startle were measured. Previous work has shown that intrathecal infusion of drugs thoug...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(90)90864-8

    authors： Boulis NM,Davis M

    更新日期：1990-08-20 00:00:00

  • Stimulation-induced status epilepticus: role of the hippocampal mossy fibers in the seizures and associated neuropathology.

    abstract：:A study of seizure activity and neuronal cell death produced by intracerebroventricular kainic acid had suggested that seizures conveyed by the hippocampal mossy fibers are more damaging to CA3 pyramidal cells than seizures conveyed by other pathways. To test this idea, the effects of a unilateral mossy fiber lesion w...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(90)91171-c

    authors： Vicedomini JP,Nadler JV

    更新日期：1990-03-26 00:00:00

  • Evidence that both intragastric and subcutaneous administration of methylenedioxymethylamphetamine (MDMA) produce serotonin neurotoxicity in rhesus monkeys.

    abstract：:It has been demonstrated that repeated, subcutaneous administration of 3,4-methylenedioxymethamphetamine (MDMA) to rats, guinea pigs, and squirrel monkeys produces long-lasting depletions of serotonin (5-hydroxytryptamine; 5-HT) in several brain regions. Since evidence of degenerating 5-HT neurons has been observed in...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(89)90700-2

    authors： Kleven MS,Woolverton WL,Seiden LS

    更新日期：1989-05-29 00:00:00

  • Mitochondrial energy metabolism and apoptosis regulation in glioblastoma.

    abstract：:Glioblastoma is the most aggressive form of gliomas and is associated with short survival. Recent advancements in molecular genetics resulted in the identification of glioma genomic, epigenomic and transcriptomic hallmarks, and multidimensional data allowed clustering of glioblastomas into molecular subtypes. Parallel...

    journal_title：Brain research

    pub_type： 杂志文章,评审

    doi：10.1016/j.brainres.2014.10.062

    authors： Nagy A,Eder K,Selak MA,Kalman B

    更新日期：2015-01-21 00:00:00

  • Kindling of the ventral tegmental area induces supersensitivity in the central dopamine system.

    abstract：:Kindling of the ventral tegmental area (VTA), a major source of the mesolimbic dopamine pathway, was examined in rats. We applied two quantitative measurements of dopamine sensitivity before and 2 weeks after VTA kindling (20 times electrical stimulations (100 microA at 1 min intervals) delivered once per day for 14 c...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2004.01.006

    authors： Watanabe T,Morimoto K,Nakamura M,Hirao T,Ninomiya T,Ando N,Suwaki H

    更新日期：2004-04-02 00:00:00

  • Remote astrocytic response of prefrontal cortex is caused by the lesions in the nucleus basalis of Meynert, but not in the ventral tegmental area.

    abstract：:The nucleus basalis of Meynert (nbM) was lesioned by injection of ibotenic acid, in 200 g male Wistar rats. The rats were killed 1, 3, 7 or 21 days after surgery, the brains were removed and the prefrontal cortices were subjected to immunohistochemical and Western blot analysis for the expression of glial fibrillary a...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(92)90800-o

    authors： Anezaki T,Yanagisawa K,Takahashi H,Nakajima T,Miyashita K,Ishikawa A,Ikuta F,Miyatake T

    更新日期：1992-03-06 00:00:00

  • Aspartate-immunoreactive primary sensory neurons in the mouse trigeminal ganglion.

    abstract：:Aspartate-immunoreactivity (ir) was examined in the mouse trigeminal ganglion (TG). The ir was detected in 34% of TG neurons and their cell bodies were of various sizes (mean +/- S.D. = 1,234 +/- 543 microm(2)). A triple immunofluorescence method revealed the co-expression of aspartate with calcitonin gene-related pep...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2006.01.092

    authors： Ichikawa H,Matsuo S,Terayama R,Yamaai T,Sugimoto T

    更新日期：2006-04-12 00:00:00

  • Effects of different corticosteroids on the brain weight and hippocampal neuronal loss in rats.

    abstract：:Equivalent antiinflammatory doses of steroids including betamethasone, methylprednisolone and dexamethasone were administered in the neonatal period in a rat model. In situ cell death in hippocampus quantified by Terminal Deoxynucleated Transferase Nick-End Labeling and on ratio of brain to body weight was investigate...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2008.10.051

    authors： Duksal F,Kilic I,Tufan AC,Akdogan I

    更新日期：2009-01-23 00:00:00

  • The growth compromised HSV-2 mutant DeltaRR prevents kainic acid-induced apoptosis and loss of function in organotypic hippocampal cultures.

    abstract：:We have previously shown that the HSV-2 anti-apoptotic protein ICP10PK is delivered by the replication incompetent virus mutant DeltaRR and prevents kainic acid (KA)-induced epileptiform seizures and neuronal cell loss in the mouse and rat models of temporal lobe epilepsy. The present studies used DeltaRR and the ICP1...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2006.08.078

    authors： Gober MD,Laing JM,Thompson SM,Aurelian L

    更新日期：2006-11-13 00:00:00

  • Plasma epinephrine modulates the cerebrovasodilation evoked by electrical stimulation of dorsal medulla.

    abstract：:We examined whether plasma epinephrine contributes to the increase in regional cerebral blood flow (rCBF) evoked by electrical stimulation of the dorsal medullary reticular formation (DMRF). Rats were anesthetized (alpha-chloralose, 30 mg/kg, s.c.), paralyzed and artificially ventilated. The DMRF was electrically stim...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(90)91203-s

    authors： Lacombe PM,Iadecola C,Underwood MD,Sved AF,Reis DJ

    更新日期：1990-01-01 00:00:00

  • Effects of atorvastatin on blood-brain barrier permeability during L-NAME hypertension followed by angiotensin-II in rats.

    abstract：:Recent studies suggest that 3-hydroxy-3 methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, statins, can have direct effects on blood vessels beyond their cholesterol-lowering effects. We investigated the effects of atorvastatin on the functional and structural properties of blood-brain barrier (BBB) and the act...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2005.02.044

    authors： Kalayci R,Kaya M,Elmas I,Arican N,Ahishali B,Uzun H,Bilgic B,Kucuk M,Kudat H

    更新日期：2005-05-03 00:00:00

  • Paraventricular hypothalamic influences on spinal nociceptive processing.

    abstract：:Oxytocin properties have been studied in different experimental models in order to obtain evidence for its analgesic properties. The analgesic effect of an oxytocinergic pathway descending from the hypothalamus reaching the dorsal horn of the spinal cord has been studied. In anesthetized rats, we recorded single units...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2006.01.050

    authors： Condés-Lara M,Rojas-Piloni G,Martínez-Lorenzana G,Rodríguez-Jiménez J,López Hidalgo M,Freund-Mercier MJ

    更新日期：2006-04-07 00:00:00

  • The effects of antidromic discharges on orthodromic firing of primary afferents in the cat.

    abstract：:This study investigated the effects of antidromically conducted nerve impulses on the transmission of orthodromic volleys in primary afferents of the hindlimb in decerebrated paralyzed cats. Two protocols were used: (A) Single skin and muscle afferents (N=20) isolated from the distal part of cut dorsal rootlets (L7-S1...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/s0006-8993(99)01236-6

    authors： Gossard JP,Bouyer L,Rossignol S

    更新日期：1999-04-17 00:00:00

  • Immunohistochemical presence of 5 alpha-reductase rat type 1-containing cells in the rat brain.

    abstract：:We showed immunohistochemically the localization of 5 alpha-reductase-containing cells in the rat brain, using a rabbit antibody generated against 5 alpha-reductase rat type 1. The antibody was produced by injecting the synthetic peptide corresponding to the amino acids 38-53 of 5 alpha-reductase rat type 1, conjugate...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(96)00188-6

    authors： Tsuruo Y,Miyamoto T,Yokoi H,Kitagawa K,Futaki S,Ishimura K

    更新日期：1996-05-25 00:00:00

  • ERP correlates of recognition memory: effects of retention interval and false alarms.

    abstract：:Within the framework of the dual process model of recognition memory, prior work with event-related potentials (ERPs) has suggested that an early component, the FN400, is a correlate of familiarity while a later component, the Late Positive Complex (LPC), is a correlate of recollection. However, other work has questio...

    journal_title：Brain research

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.brainres.2006.04.050

    authors： Wolk DA,Schacter DL,Lygizos M,Sen NM,Holcomb PJ,Daffner KR,Budson AE

    更新日期：2006-06-22 00:00:00

  • Bulbar pathway for contralateral lingual nerve-evoked reflex vasodilatation in cat palate.

    abstract：:We investigated the brain-stem pathway(s) by which electrical stimulation of the central cut end of the lingual nerve (LN) evokes parasympathetic reflex vasodilatation in the palate contralateral to the stimulated side. This occurs in artificially ventilated, cervically vagosympathectomized cats deeply anesthetized wi...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2004.06.010

    authors： Mizuta K,Izumi H

    更新日期：2004-09-10 00:00:00

  • Locomotor activity in the ischemic gerbil.

    abstract：:Previous studies have shown that within 24 h after ischemic insult, gerbils exhibit an increase in locomotor activity. Because activity gradually diminishes to normal levels with repeated testing, it has been argued that this behavior represents a reversible or transient effect of ischemia. The present study challenge...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(93)91081-3

    authors： Babcock AM,Baker DA,Lovec R

    更新日期：1993-10-22 00:00:00

  • Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.

    abstract：:Hydrogen-rich water (HRW) has anti-oxidant activities, and it exerts neuroprotective effects during ischemia-reperfusion brain injury. Parvalbumin and hippocalcin are two calcium buffering proteins, which are involved in neuronal differentiation, maturation and apoptosis. The aim of this study was to investigate wheth...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2015.04.038

    authors： Han L,Tian R,Yan H,Pei L,Hou Z,Hao S,Li YV,Tian Q,Liu B,Zhang Q

    更新日期：2015-07-30 00:00:00

  • Localization of angiotensin-converting enzyme, angiotensin II, angiotensin II receptor subtypes, and vasopressin in the mouse hypothalamus.

    abstract：:The hypothalamic angiotensin II (Ang II) system plays an important role in pituitary hormone release. Little is known about this system in the mouse brain. We studied the distribution of angiotensin-converting-enzyme (ACE), Ang II, Ang II receptor subtypes, and vasopressin in the hypothalamus of adult male mice. Autor...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/s0006-8993(97)00220-5

    authors： Jöhren O,Imboden H,Häuser W,Maye I,Sanvitto GL,Saavedra JM

    更新日期：1997-05-23 00:00:00

  • Freeze-fracture ultrastructure of the perinodal astrocyte and associated glial junctions.

    abstract：:Freeze-fracture examination of nodes of Ranvier from adult rat optic nerve demonstrates the presence of astrocytic processes at the majority of nodes of Ranvier. Astrocytic processes often run along the entire length of the nodal gap, although they do not necessarily encircle the entire nodal circumference. The E- and...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(84)90919-3

    authors： Waxman SG,Black JA

    更新日期：1984-08-06 00:00:00

  • Response of rat brain to calcitonin alteration.

    abstract：:Endogenous calcitonin was altered in rats by thyroparathyroidectomy, followed by supplementation with thyroxine and calcium. As a result, a reduction in the content of 5-hydroxytryptamine in the brain together with an increase in the concentration of tryptophan in the plasma were observed. The changes were accompanied...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(82)90129-9

    authors： Nakhla AM,Latif A

    更新日期：1982-04-29 00:00:00

  • Medullary expiratory neurons in the decerebrate rat: an intracellular study.

    abstract：:Intracellular recordings and labelings with horseradish peroxidase (HRP) of expiratory (E) neurons were performed in decerebrate, paralyzed, and ventilated rats. A total of 37 neurons were recorded, from which 4 cells and 1 axon were labeled. They were located in two regions of the ventrolateral medulla. One was in th...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(92)90687-5

    authors： Zheng Y,Barillot JC,Bianchi AL

    更新日期：1992-04-03 00:00:00

  • Release of excitatory and inhibitory amino acids from the locus coeruleus of conscious rats by cardiovascular stimuli and various forms of acute stress.

    abstract：:The release of amino acids in the locus coeruleus (LC) of conscious, freely moving rats was studied in time periods of 3 min by use of push-pull superfusion under basal conditions and during application of various experimental stimuli known to influence the activity of the LC-noradrenergic system. Tail pinch for 3 min...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(95)01102-1

    authors： Singewald N,Zhou GY,Schneider C

    更新日期：1995-12-15 00:00:00

  • Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man.

    abstract：:Recently, the gene encoding the cerebrovascular and neuritic plaque amyloid, a pathologic stigma of Alzheimer's disease (AD), has been molecularly cloned and mapped to human chromosome 21, band q21. Changes in the brains of individuals with trisomy 21 (Down syndrome, DS) over 35 years of age closely resemble AD neurop...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0169-328x(87)90028-3

    authors： Reeves RH,Robakis NK,Oster-Granite ML,Wisniewski HM,Coyle JT,Gearhart JD

    更新日期：1987-09-01 00:00:00

  • Identification of differentially expressed proteins in the spinal cord of neuropathic pain models with PKCgamma silence by proteomic analysis.

    abstract：:In order to elucidate the mechanisms that PKCγ regulates neuropathic pain (NP), and detect proteins that are associated with the function of PKCγ in NP, we exploited a chronic constriction injury (CCI)-induced neuropathic pain rat (CCI-NP rat) model in which PKCγ knockdown in the spinal cord was successfully carried o...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2011.12.046

    authors： Zou W,Zhan X,Li M,Song Z,Liu C,Peng F,Guo Q

    更新日期：2012-02-27 00:00:00

  • Topographical distribution of dopaminergic innervation and of dopaminergic receptors in the rat striatum. II. Distribution and characteristics of dopamine adenylate cyclase--interaction of d-LSD with dopaminergic receptors.

    abstract：:The characteristics of dopamine adenylate cyclase in the rat striatum were first studied on homogenates of fresh tissues. In the assay conditions used, dopamine (10(-4) M) stimulated the enzyme activity by 250%. This effect was completely blocked by fluphenazine (10(-5) M; Ki=9X10(-9) M) and by phentolamine (10(-5) M;...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(76)90228-6

    authors： Bockaert J,Premont J,Glowinski J,Thierry AM,Tassin JP

    更新日期：1976-05-07 00:00:00